STEFFEN THIEL: Innate Immune system

Steffen Thiel’s research focus is the processes that create inflammation in the body and his group is among the leaders in the field of immune recognition.

Steffen Thiel has been deeply involved in the description of the proteins and processes in the part of the immune system referred to as the complement system.

Recent publications

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Sokołowska, A., Świerzko, A. S., Szala-Poździej, A., Augustynowicz-Kopeć, E., Kozińska, M., Niemiec, T., Błachnio, M., Borkowska-Tatar, D., Jensenius, J. C., Thiel, S., Dziadek, J. & Cedzyński, M. (2020). Selected factors of the innate immunity in Polish patients suffering from pulmonary tuberculosis. Immunobiology, 225(3), 151905. Artikel 151905. https://doi.org/10.1016/j.imbio.2020.151905

Bro-Jeppesen, J., Jeppesen, A. N., Haugaard, S., Troldborg, A., Hassager, C., Kjaergaard, J., Kirkegaard, H., Wanscher, M., Hvas, A.-M. & Thiel, S. (2020). The complement lectin pathway protein MAp19 and out-of-hospital cardiac arrest: Insights from two randomized clinical trials. European Heart Journal: Acute Cardiovascular Care, 9(4_Suppl), S145-S152. https://doi.org/10.1177/2048872619870031

Gregersen, E., Betzer, C., Kim, W. S., Kovacs, G., Reimer, L., Halliday, G. M., Thiel, S. & Jensen, P. H. (2021). Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity. Journal of Neuroinflammation, 18(1), Artikel 177. https://doi.org/10.1186/s12974-021-02225-9

Juul-Madsen, K., Troldborg, A., Wittenborn, T. R., Axelsen, M. G., Zhao, H., Klausen, L. H., Luecke, S., Paludan, S. R., Stengaard-Pedersen, K., Dong, M., Møller, H. J., Thiel, S., Jensen, H., Schuck, P., Sutherland, D. S., Degn, S. E. & Vorup-Jensen, T. (2021). Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus. Proceedings of the National Academy of Sciences (PNAS), 118(30), Artikel e2106647118. https://doi.org/10.1073/pnas.2106647118

Hoffmann-Petersen, I. T., Holt, C. B., Jensen, L., Hage, C., Mellbin, L. G., Thiel, S., Hansen, T. K. & Østergaard, J. A. (2021). Effect of dipeptidyl peptidase-4 inhibitors on complement activation. Diabetes/Metabolism Research and Reviews, 37(3), Artikel e3385. https://doi.org/10.1002/dmrr.3385

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Revideret 30.07.2026

Viktor Hauge Ladegaard