Højgaard, C.
, Sørensen, H. V., Pedersen, J. S., Winther, J. R.
& Otzen, D. E. (2018).
Can a Charged Surfactant Unfold an Uncharged Protein? Biophysical Journal,
115(11), 2081-2086.
https://doi.org/10.1016/j.bpj.2018.10.022Favre-Bulle, I. A.
, Vanwalleghem, G., Taylor, M. A., Rubinsztein-Dunlop, H. & Scott, E. K. (2018).
Cellular-Resolution Imaging of Vestibular Processing across the Larval Zebrafish Brain.
Current Biology,
28(23), 3711-3722.e3.
https://doi.org/10.1016/j.cub.2018.09.060de Jong, S., Diniz, M. J. A., Saloma, A., Gadelha, A., Santoro, M. L., Ota, V. K., Noto, C., Curtis, C., Newhouse, S. J., Patel, H., Hall, L. S., O Reilly, P. F., Belangero, S. I., Bressan, R. A., Breen, G. & Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium (Per Qvist and Preben Bo Mortensen, members of-) (2018).
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.
Communications Biology,
1(1), Article 163.
https://doi.org/10.1038/s42003-018-0155-yHede, M. S., Fjelstrup, S., Lötsch, F., Zoleko, R. M., Klicpera, A., Groger, M., Mischlinger, J., Endame, L., Veletzky, L., Neher, R.
, Simonsen, A. K. W., Petersen, E., Mombo-Ngoma, G.
, Stougaard, M., Ho, Y.-P., Labouriau, R., Ramharter, M.
& Knudsen, B. R. (2018).
Detection of the Malaria causing Plasmodium Parasite in Saliva from Infected Patients using Topoisomerase I Activity as a Biomarker.
Scientific Reports,
8(1), 4122. Article 4122.
https://doi.org/10.1038/s41598-018-22378-7
Dahl, M.
, Daugaard, I., Andersen, M. S., Hansen, T. B., Grønbæk, K., Kjems, J. & Kristensen, L. S. (2018).
Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies.
Laboratory Investigation,
98(12), 1657–1669.
https://doi.org/10.1038/s41374-018-0108-6Maier, R. M., Zhu, Z., Lee, S. H., Trzaskowski, M., Ruderfer, D. M., Stahl, E. A., Ripke, S., Wray, N. R.
, Yang, J., Visscher, P. M., Robinson, M. R., Forstner, A. J., Mcquillin, A., Trubetskoy, V., Wang, W., Wang, Y., Coleman, J. R. I., Gaspar, H. A., De Leeuw, C. A. ... Zammit, S. (2018).
Improving genetic prediction by leveraging genetic correlations among human diseases and traits.
Nature Communications,
9(1), Article 989.
https://doi.org/10.1038/s41467-017-02769-6Greibe, E., Mahalle, N., Bhide, V.
, Heegaard, C. W., Naik, S.
& Nexø, E. (2018).
Increase in circulating holotranscobalamin after oral administration of cyanocobalamin or hydroxocobalamin in healthy adults with low and normal cobalamin status.
European Journal of Nutrition,
57(8), 2847-2855. Article 8.
https://doi.org/10.1007/s00394-017-1553-5
Koch, B. E. V., Yang, S., Lamers, G.
, Stougaard, J. & Spaink, H. P. (2018).
Intestinal microbiome adjusts the innate immune setpoint during colonization through negative regulation of MyD88.
Nature Communications,
9(1), Article 4099.
https://doi.org/10.1038/s41467-018-06658-4
Schmidt, E., Dhaouadi, I., Gaziano, I., Oliverio, M., Klemm, P., Awazawa, M., Mitterer, G., Fernandez-Rebollo, E., Pradas-Juni, M., Wagner, W., Hammerschmidt, P., Loureiro, R., Kiefer, C., Hansmeier, N. R., Khani, S., Bergami, M., Heine, M.
, Ntini, E., Frommolt, P. ... Kornfeld, J. W. (2018).
LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat.
Nature Communications,
9(1), Article 3622.
https://doi.org/10.1038/s41467-018-05933-8Fang, L., Sørensen, P., Sahana, G., Panitz, F., Su, G., Zhang, S., Yu, Y.
, Li, B., Ma, L., Liu, G.
, Lund, M. S. & Thomsen, B. (2018).
MicroRNA-guided prioritization of genome-wide association signals reveals the importance of microRNA-target gene networks for complex traits in cattle.
Scientific Reports,
8(1), Article 9345.
https://doi.org/10.1038/s41598-018-27729-y
Olagnier, D., Brandtoft, A. M., Gunderstofte, C., Villadsen, N. L., Krapp, C., Thielke, A. L., Laustsen, A., Peri, S.
, Hansen, A. L., Bonefeld, L., Thyrsted, J., Bruun, V., Iversen, M. B., Lin, L., Artegoitia, V. M., Su, C., Yang, L., Lin, R., Balachandran, S.
... Holm, C. K. (2018).
Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming.
Nature Communications,
9(1), Article 3506.
https://doi.org/10.1038/s41467-018-05861-7
Christensen, E., Nordentoft, I., Vang, S., Birkenkamp-Demtröder, K., Jensen, J. B., Agerbæk, M., Pedersen, J. S. & Dyrskjøt, L. (2018).
Optimized targeted sequencing of cell-free plasma DNA from bladder cancer patients.
Scientific Reports,
8(1), Article 1917.
https://doi.org/10.1038/s41598-018-20282-8
Hornshøj, H., Nielsen, M. M., Sinnott-Armstrong, N. A.
, Świtnicki, M. P., Juul, M., Madsen, T., Sallari, R., Kellis, M.
, Ørntoft, T., Hobolth, A. & Pedersen, J. S. (2018).
Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival.
npj Genomic Medicine,
3(1), 1. Article 40.
https://doi.org/10.1038/s41525-017-0040-5
Moller, A. M. J.
, Fuchtbauer, E.-M., Bruel, A., Andersen, T. L., Borggaard, X. G., Pavlos, N. J.
, Thomsen, J. S., Pedersen, F. S., Delaisse, J.-M. & Soe, K. (2018).
Septins are critical regulators of osteoclastic bone resorption.
Scientific Reports,
8(1), Article 13016.
https://doi.org/10.1038/s41598-018-31159-1Jabs, F., Plum, M., Laursen, N. S., Jensen, R. K., Mølgaard, B., Miehe, M., Mandolesi, M., Rauber, M. M., Pfützner, W., Jakob, T., Möbs, C.
, Andersen, G. R. & Spillner, E. (2018).
Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction.
Nature Communications,
9(1), Article 7.
https://doi.org/10.1038/s41467-017-02312-7
Fogh, M., Hollensted, M., Schnurr, T. M., Kloppenborg, J. T., Have, C. T., Ruest Haarmark Nielsen, T., Rask, J., Asp Vonsild Lund, M., Frithioff-Bøjsøe, C., Østergaard Johansen, M., Vincent Rosenbaum Appel, E., Mahendran, Y.
, Grarup, N., Kadarmideen, H. N., Pedersen, O., Holm, J.-C. & Hansen, T. (2018).
Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention in Danish Children.
Obesity,
26(12), 1915-1922.
https://doi.org/10.1002/oby.22308
Ivanovaite, L., Bjørnevad, M., Philippsen, B., Hoggard, C. S., Enghild, J. J., Scavenius, C., Vasiliauskaite, A., Dručkuvienė, G.
, Jensen, P., Maring, R., Dodd, J. A., Serwatka, K.
& Riede, F. (2018).
Making silent bones speak: The analysis of orphaned osseous tools illustrated with Mesolithic stray finds.
Archaeologia Baltica,
25, 53-70.
https://doi.org/10.15181/ab.v25i0.1830
Lloret-Llinares, M., Karadoulama, E., Chen, Y., Wojenski, L. A., Villafano, G. J., Bornholdt, J., Andersson, R., Core, L., Sandelin, A.
& Jensen, T. H. (2018).
The RNA exosome contributes to gene expression regulation during stem cell differentiation.
Nucleic Acids Research,
46(21), 11502-11513.
https://doi.org/10.1093/nar/gky817
Yatime, L., Merle, N. S.
, Hansen, A. G., Friis, N. A., Østergaard, J. A., Bjerre, M., Roumenina, L. T.
, Thiel, S., Kristensen, P. & Andersen, G. R. (2018).
A single-domain antibody targeting complement component c5 acts as a selective inhibitor of the terminal pathway of the complement system and thus functionally mimicks the c-terminal domain of the staphylococcus aureusSSL7 protein.
Frontiers in Immunology,
9, Article 2822.
https://doi.org/10.3389/fimmu.2018.02822
Compte, M.
, Harwood, S. L., Muñoz, I. G., Navarro, R., Zonca, M., Perez-Chacon, G., Erce-Llamazares, A., Merino, N., Tapia-Galisteo, A., Cuesta, A. M.
, Mikkelsen, K., Caleiras, E., Nuñez-Prado, N., Aznar, M. A.
, Lykkemark, S., Martínez-Torrecuadrada, J., Melero, I., Blanco, F. J., Bernardino de la Serna, J.
... Alvarez-Vallina, L. (2018).
A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity.
Nature Communications,
9, Article 4809 .
https://doi.org/10.1038/s41467-018-07195-wKurnik, M., Sahin, C., Andersen, C. B., Lorenzen, N., Giehm, L., Mohammad-Beigi, H., Jessen, C. M., Pedersen, J. S., Christiansen, G., Petersen, S. V., Staal, R., Krishnamurthy, G., Pitts, K., Reinhart, P. H.
, Mulder, F. A. A., Mente, S., Hirst, W. D.
& Otzen, D. E. (2018).
Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State.
Cell Chemical Biology,
25(11), 1389-1402.e9.
https://doi.org/10.1016/j.chembiol.2018.08.005
Jacobs, S., Wavreil, F., Schepens, B.
, Gad, H. H., Hartmann, R., Rocha-Pereira, J., Neyts, J., Saelens, X. & Michiels, T. (2018).
Species Specificity of Type III Interferon Activity and Development of a Sensitive Luciferase-Based Bioassay for Quantitation of Mouse Interferon-λ.
Journal of Interferon & Cytokine Research,
38(11), 469–479.
https://doi.org/10.1089/jir.2018.0066Christensen, L. F. B., Hansen, L. M.
, Finster, K., Christiansen, G., Nielsen, P. H.
, Otzen, D. E. & Dueholm, M. S. (2018).
The Sheaths of Methanospirillum Are Made of a New Type of Amyloid Protein.
Frontiers in Microbiology,
9(NOV), Article 2729.
https://doi.org/10.3389/fmicb.2018.02729,
https://doi.org/10.3389/fmicb.2018.02729
Wang, Q., Taschner, M., Ganzinger, K. A., Kelley, C., Villasenor, A., Heymann, M., Schwille, P.
, Lorentzen, E. & Mizuno, N. (2018).
Membrane association and remodeling by intraflagellar transport protein IFT172.
Nature Communications,
9(1), Article 4684.
https://doi.org/10.1038/s41467-018-07037-9Longhin, E., Grønberg, C., Hu, Q., Duelli, A. S.
, Andersen, K. R., Laursen, N. S. & Gourdon, P. (2018).
Isolation and Characterization of Nanobodies against a Zinc-Transporting P-Type ATPase.
Antibodies,
7(4), Article 39.
https://doi.org/10.3390/antib7040039Shliaha, P. V., Gibb, S., Gorshkov, V., Jespersen, M. S.
, Andersen, G. R., Bailey, D., Schwartz, J., Eliuk, S., Schwämmle, V. & Jensen, O. N. (2018).
Maximizing Sequence Coverage in Top-Down Proteomics by Automated Multimodal Gas-Phase Protein Fragmentation.
Analytical Chemistry,
90(21), 12519-12526.
https://doi.org/10.1021/acs.analchem.8b02344Hennessy, R. C., Jørgensen, N. O. G.
, Scavenius, C., Enghild, J. J., Greve-Poulsen, M., Sørensen, O. B.
& Stougaard, P. (2018).
A Screening Method for the Isolation of Bacteria Capable of Degrading Toxic Steroidal Glycoalkaloids Present in Potato.
Frontiers in Microbiology,
9, Article 2648.
https://doi.org/10.3389/fmicb.2018.02648Fragata, I., Matuszewski, S., Schmitz, M. A.
, Bataillon, T., Jensen, J. D. & Bank, C. (2018).
The fitness landscape of the codon space across environments.
Heredity,
121(5), 422-437.
https://doi.org/10.1038/s41437-018-0125-7Jacobsen, K. M., Villadsen, N. L., Tørring, T., Nielsen, C. B., Salomón, T., Nielsen, M. M., Tsakos, M., Sibbersen, C., Scavenius, C., Nielsen, R., Christensen, E. I., Guerra, P. F., Bross, P., Pedersen, J. S., Enghild, J. J., Johannsen, M., Frøkiær, J., Overgaard, J., Horsman, M. R. ... Poulsen, T. B. (2018).
APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells.
Cell Chemical Biology,
25(11), 1337-1349.e12.
https://doi.org/10.1016/j.chembiol.2018.07.010
Thornton, L. M., Munn-Chernoff, M. A., Baker, J. H., Juréus, A., Parker, R., Henders, A. K.
, Larsen, J. T., Petersen, L., Watson, H. J., Yilmaz, Z., Kirk, K. M., Gordon, S., Leppä, V. M., Martin, F. C., Whiteman, D. C., Olsen, C. M., Werge, T. M., Pedersen, N. L., Kaye, W. ... Bulik, C. M. (2018).
The anorexia nervosa genetics initiative (ANGI): Overview and methods.
Contemporary Clinical Trials,
74, 61-69.
https://doi.org/10.1016/j.cct.2018.09.015Smith, Y. E., Toomey, S., Napoletano, S., Kirwan, G., Schadow, C., Chubb, A. J.
, Mikkelsen, J. H., Oxvig, C. & Harmey, J. H. (2018).
Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer.
BMC Cancer,
18, Article 1016.
https://doi.org/10.1186/s12885-018-4950-0Greibe, E., Nymark, O., Fedosov, S., Heegaard, C. W. & Nexø, E. (2018).
Differences in tissue distribution of cyano-B12 and hydroxo-B12 one week after oral intake: An experimental study in male Wistar rats.
Nutrients,
10(10), Article 1487.
https://doi.org/10.3390/nu10101487
Bleem, A.
, Christiansen, G., Madsen, D. J., Maric, H., Strømgaard, K., Bryers, J. D., Daggett, V.
, Meyer, R. L. & Otzen, D. E. (2018).
Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms.
Journal of Molecular Biology,
430(20), 3751-3763.
https://doi.org/10.1016/j.jmb.2018.06.043Tsikou, D., Yan, Z., Holt, D. B., Abel, N. B., Reid, D. E., Madsen, L. H., Bhasin, H., Sexauer, M.
, Stougaard, J. & Markmann, K. (2018).
Systemic control of legume susceptibility to rhizobial infection by a mobile microRNA.
Science,
362(6411), 233-236.
https://doi.org/10.1126/science.aat6907
Ludvigsen, M., Bjerregård Pedersen, M., Lystlund Lauridsen, K., Svenstrup Poulsen, T.
, Hamilton-Dutoit, S. J., Besenbacher, S., Bendix, K., Møller, M. B.
, Nørgaard, P., d'Amore, F. & Honoré, B. (2018).
Proteomic profiling identifies outcome-predictive markers in patients with peripheral T-cell lymphoma, not otherwise specified.
Blood Advances,
2(19), 2533-2542.
https://doi.org/10.1182/bloodadvances.2018019893
Pujols, J.
, Peña-Díaz, S., Lázaro, D. F., Peccati, F.
, Pinheiro, F., González, D., Carija, A., Navarro, S., Conde-Giménez, M., García, J., Guardiola, S., Giralt, E., Salvatella, X., Sancho, J., Sodupe, M., Outeiro, T. F., Dalfó, E. & Ventura, S. (2018).
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
Proceedings of the National Academy of Sciences of the United States of America,
115(41), 10481-10486.
https://doi.org/10.1073/pnas.1804198115Shimizu, M., Narboux-Nême, N., Gitton, Y., de Lombares, C., Fontaine, A., Alfama, G.
, Kitazawa, T., Kawamura, Y., Heude, E., Marshall, L., Higashiyama, H., Wada, Y., Kurihara, Y., Kurihara, H. & Levi, G. (2018).
Probing the origin of matching functional jaws: roles of Dlx5/6 in cranial neural crest cells.
Scientific Reports,
8(1), 14975.
https://doi.org/10.1038/s41598-018-33207-2Lykke-Andersen, S., Ardal, B. K., Hollensen, A. K., Damgaard, C. K. & Jensen, T. H. (2018).
Box C/D snoRNP Autoregulation by a cis-Acting snoRNA in the NOP56 Pre-mRNA.
Molecular Cell,
72(1), 99-111.e5.
https://doi.org/10.1016/j.molcel.2018.08.017
