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Department of Molecular Biology and Genetics

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Latest peer-reviewed publications at MBG

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Displaying results 1951 to 95 out of 95

Peer-reviewed publications at MBG - all years

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Nadzieja, M., Kelly, S., Stougaard, J. & Reid, D. (2018). Epidermal auxin biosynthesis facilitates rhizobial infection in Lotus japonicus. Plant Journal, 95(1), 101-111. https://doi.org/10.1111/tpj.13934

Lukassen, M. V., Poulsen, E. T. & Enghild, J. J. (2018). Identification of redox-sensitive protein interactions in the human cornea. Abstract from Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu. https://iovs.arvojournals.org/article.aspx?articleid=2690443&resultClick=1

Kvirkvelia, N., Chikadze, N., Makinde, J., McBride, J. D., Porakishvili, N., Hills, F. A., Martensen, P. M., Justesen, J., Delves, P. J., Lund, T. & Roitt, I. M. (2018). Investigation of factors influencing the immunogenicity of hCG as a potential cancer vaccine. Clinical and Experimental Immunology, 193(1), 73-83. https://doi.org/10.1111/cei.13131

Subrizi, A., Yang, C., Ilmarinen, T., Skottman, H., Urtti, A. & Kjems, J. (2018). Lipidoid-siRNA formulations promote gene silencing in differentiated and nondividing ARPE-19, primary porcine and human embryonic stem cell-derived retinal pigment epithelial cells. Abstract from Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Honolulu. https://iovs.arvojournals.org/article.aspx?articleid=2693003&resultClick=1

Nielsen, N. S., Ammitzbøll, T. A., Thøgersen, I., Poulsen, E. T. & Enghild, J. J. (2018). Structural characterization of corneal dystrophy-related TGFBIp mutants. Investigative Ophthalmology & Visual Science, 59(9), Article E-Abstract 2254. https://iovs.arvojournals.org/article.aspx?articleid=2690435&resultClick=1

Jensen, A. B., Joergensen, H. B., Dam, V. S., Kamaev, D., Boedtkjer, D., Füchtbauer, E. M., Aalkjaer, C. & Matchkov, V. V. (2018). Variable Contribution of TMEM16A to Tone in Murine Arterial Vasculature. Basic and Clinical Pharmacology and Toxicology, 123(1), 30-41. https://doi.org/10.1111/bcpt.12984

Murra, M., Lützen, L., Barut, A., Zbinden, R., Lund, M., Villesen, P. & Nørskov-Lauritsen, N. (2018). Whole-genome sequencing of aggregatibacter species isolated from human clinical specimens and description of Aggregatibacter kilianii sp. Nov. Journal of Clinical Microbiology, 56(7), Article UNSP e00053-18. https://doi.org/10.1128/JCM.00053-18

Rattan, S. I. S. (2018). Biogerontology: research status, challenges and opportunities. Acta bio-medica : Atenei Parmensis, 89(2), 291-301. https://doi.org/10.23750/abm.v89i2.7403

Selnihhin, D., Sparvath, S. M., Preus, S., Birkedal, V. & Andersen, E. S. (2018). Multifluorophore DNA Origami Beacon as a Biosensing Platform. ACS Nano, 12(6), 5699–5708. https://doi.org/10.1021/acsnano.8b01510

Brainstorm Consortium (2018). Analysis of shared heritability in common disorders of the brain. Science, 360(6395), eaap8757. Article 8757. https://doi.org/10.1126/science.aap8757

Rennie, S., Dalby, M., Lloret-Llinares, M., Bakoulis, S., Dalager Vaagensø, C., Heick Jensen, T. & Andersson, R. (2018). Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter-encoded enhancer activities. Nucleic Acids Research, 46(11), 5455–5469. https://doi.org/10.1093/nar/gky244

Louloupi, A., Ntini, E., Conrad, T. & Ørom, U. A. V. (2018). Transient N-6-Methyladenosine Transcriptome Sequencing Reveals a Regulatory Role of m6A in Splicing Efficiency. Cell Reports, 23(12), 3429-3437. https://doi.org/10.1016/j.celrep.2018.05.077

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium (2018). Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. Cell, 173(7), 1705-1715.e16. https://doi.org/10.1016/j.cell.2018.05.046

Yang, C., Gao, S., Song, P., Dagnæs-Hansen, F., Jakobsen, M. V. & Kjems, J. (2018). Theranostic Niosomes for Efficient siRNA/microRNA Delivery and Activatable Near-Infrared Fluorescent Tracking of Stem Cells. A C S Applied Materials and Interfaces, 10(23), 19494–19503. https://doi.org/10.1021/acsami.8b05513

Torvund-Jensen, J., Steengaard, J., Askebjerg, L. B., Kjaer-Sorensen, K. & Laursen, L. S. (2018). The 3’UTRs of myelin basic protein mRNAs regulate transport, local translation and sensitivity to neuronal activity in zebrafish. Frontiers in Molecular Neuroscience, 11, Article 185. https://doi.org/10.3389/fnmol.2018.00185

Harms, A., Brodersen, D. E., Mitarai, N. & Gerdes, K. (2018). Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology. Molecular Cell, 70(5), 768-784. https://doi.org/10.1016/j.molcel.2018.01.003

Valero Moreno, J., Pal, N., Dhakal, S., Walter, N. G. & Famulok, M. (2018). A bio-hybrid DNA rotor–stator nanoengine that moves along predefined tracks. Nature Nanotechnology, 13(6), 496-503. https://doi.org/10.1038/s41565-018-0109-z

Feyera, T., Pedersen, T. F., Larsen, U. K., Foldager, L. & Theil, P. K. (2018). Impact of sow energy status during farrowing on farrowing kinetics, frequency of stillborn piglets, and farrowing assistance: Sow energy status and farrowing kinetics. Journal of Animal Science, 96(6), 2320–2331. Article 96. https://doi.org/10.1093/jas/sky141

Hashiguchi, M., Tanaka, H., Muguerza, M., Akashi, R., Sandal, N. N., Andersen, S. U. & Sato, S. (2018). Lotus japonicus Genetic, Mutant, and Germplasm Resources. Current Protocols in Plant Biology, 3(2), e20070. Article e20070. https://doi.org/10.1002/cppb.20070

Winge, S. B., Dalgaard, M. D., Belling, K. G., Jensen, J. M., Nielsen, J. E., Aksglaede, L., Schierup, M. H., Brunak, S., Skakkebæk, N. E., Juul, A., Rajpert-De Meyts, E. & Almstrup, K. (2018). Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells article. Cell Death and Disease, 9(6), Article 586. https://doi.org/10.1038/s41419-018-0671-1

Jørgensen, S. E., Christiansen, M., Ryø, L. B., Gad, H. H., Gjedsted, J., Staeheli, P., Mikkelsen, J. G., Storgaard, M., Hartmann, R. & Mogensen, T. H. (2018). Defective RNA sensing by RIG-I in severe influenza virus infection. Clinical and Experimental Immunology, 192(3), 366-376. https://doi.org/10.1111/cei.13120

Larsen, K. E., Kristensen, K. K. & Callesen, H. (2018). DNA methyltransferases and tRNA methyltransferase DNMT2 in developing pig brain - expression and promoter methylation. Gene Reports, 11, 42-51. https://doi.org/10.1016/j.genrep.2018.02.003

Tiwari, M. K., Leinisch, F., Sahin, C., Møller, I. M., Otzen, D., Davies, M. J. & Bjerrum, M. J. (2018). Early events in copper-ion catalyzed oxidation of α-synuclein. Free Radical Biology & Medicine, 121, 38-50. https://doi.org/10.1016/j.freeradbiomed.2018.04.559

Vanwalleghem, G. C., Ahrens, M. B. & Scott, E. K. (2018). Integrative whole-brain neuroscience in larval zebrafish. Current Opinion in Neurobiology, 50, 136-145. https://doi.org/10.1016/j.conb.2018.02.004

Magne, K., George, J., Berbel Tornero, A., Broquet, B., Madueño, F., Andersen, S. U. & Ratet, P. (2018). Lotus japonicus NOOT-BOP-COCH-LIKE1 is essential for nodule, nectary, leaf and flower development. Plant Journal, 94(5), 880-894. https://doi.org/10.1111/tpj.13905

Hansen, S. F., Petrat-Melin, B., Rasmussen, J. T., Larsen, L. B., S. Ostenfeld, M. & Wiking, L. (2018). Placing pasteurisation before or after microfiltration impacts the protein composition of milk fat globule membrane material. International Dairy Journal, 81, 35-41. https://doi.org/10.1016/j.idairyj.2017.12.015

Espelund, U., Renehan, A. G., Cold, S., Oxvig, C., Lancashire, L., Su, Z., Flyvbjerg, A. & Frystyk, J. (2018). Prognostic relevance and performance characteristics of serum IGFBP-2 and PAPP-A in women with breast cancer: a long-term Danish cohort study. Cancer Medicine, 7(6), 2391-2404. https://doi.org/10.1002/cam4.1504

Kornerup, L. S., Fedosov, S., Juul, C. B., Greibe, E., Heegaard, C. W. & Nexø, E. (2018). Tissue distribution of oral vitamin B12 is influenced by B12 status and B12 form: an experimental study in rats. European Journal of Nutrition, 57(4), 1459-1469. Article 4. https://doi.org/10.1007/s00394-017-1424-0

Zhang, N., Rao, R. S. P., Salvato, F., Havelund, J. F., Møller, I. M., Thelen, J. J. & Xu, D. (2018). MU-LOC: A machine-learning method for predicting mitochondrially localized proteins in plants. Frontiers in Plant Science, 9, Article 634. https://doi.org/10.3389/fpls.2018.00634

Aliakbari, F., Mohammad-Beigi, H., Rezaei-Ghaleh, N., Becker, S., Dehghani Esmatabad, F., Eslampanah Seyedi, H. A., Bardania, H., Tayaranian Marvian, A., Collingwood, J. F., Christiansen, G., Zweckstetter, M., Otzen, D. E. & Morshedi, D. (2018). The potential of zwitterionic nanoliposomes against neurotoxic alpha-synuclein aggregates in Parkinson's Disease. Nanoscale, 10(19), 9174-9185. https://doi.org/10.1039/c8nr00632f

Knudsen, C. H., ásgrímsdóttir, E. S., Rahimi, K., Gill, K. P., Frandsen, S., Buchholdt, S. H., Chen, M., Kjems, J., Febbraro, F. & Denham, M. (2018). A modified monomeric red fluorescent protein reporter for assessing CRISPR activity. Frontiers in Cell and Developmental Biology, 6(MAY), Article 54. https://doi.org/10.3389/fcell.2018.00054

Skotte, N. H., Andersen, J. V., Santos, A., Aldana, B. I., Willert, C. W., Nørremølle, A., Waagepetersen, H. S. & Nielsen, M. L. (2018). Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism. Cell Reports, 23(7), 2211-2224. https://doi.org/10.1016/j.celrep.2018.04.052

Silla, T., Karadoulama, E., Mąkosa, D., Lubas, M. & Jensen, T. H. (2018). The RNA Exosome Adaptor ZFC3H1 Functionally Competes with Nuclear Export Activity to Retain Target Transcripts. Cell Reports, 23(7), 2199-2210. https://doi.org/10.1016/j.celrep.2018.04.061

Kofoed, R. H., Betzer, C., Lykke-Andersen, S., Molska, E. & Jensen, P. H. (2018). Investigation of RNA Synthesis Using 5-Bromouridine Labelling and Immunoprecipitation. Journal of Visualized Experiments, 2018(135), Article e57056. https://doi.org/10.3791/57056

van der Weijden, V. A., Flöter, V. L. & Ulbrich, S. E. (2018). Gestational oral low-dose estradiol-17β induces altered DNA methylation of CDKN2D and PSAT1 in embryos and adult offspring. Scientific Reports, 8(1), 7494. https://doi.org/10.1038/s41598-018-25831-9

Christensen, L. F. B., Otzen, D. & Dueholm, M. S. (2018). High-quality draft genome sequence of Sphaerisporangium cinnabarinum ATCC 31213. Genome Announcements, 6(21), Article e00456-18. https://doi.org/10.1128/genomeA.00456-18

Skinkyte-Juskiene, R., Kogelman, L. J. A. & Kadarmideen, H. N. (2018). Transcription factor co-expression networks of adipose RNA-Seq data reveal regulatory mechanisms of obesity. Current Genomics, 19(4), 289-299. https://doi.org/10.2174/1389202918666171005095059

Harboe, M., Torvund-Jensen, J., Kjaer-Sorensen, K. & Laursen, L. S. (2018). Ephrin-A1-EphA4 signaling negatively regulates myelination in the central nervous system. Glia, 66(5), 934-950. https://doi.org/10.1002/glia.23293

Andersen, K. K., Vad, B. S., Kjaer, L., Tolker-Nielsen, T., Christiansen, G. & Otzen, D. E. (2018). Pseudomonas aeruginosa rhamnolipid induces fibrillation of human α-synuclein and modulates its effect on biofilm formation. FEBS Letters, 592(9), 1484-1496. https://doi.org/10.1002/1873-3468.13038

Cediel, G., Rueda, F., Oxvig, C., Oliveras, T., Labata, C., de Diego, O., Ferrer, M., Aranda-Nevado, M. C., Serra-Gregori, J., Núñez, J., García, C. & Bayes-Genis, A. (2018). Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction. Cardiovascular Diabetology, 17, Article 63. https://doi.org/10.1186/s12933-018-0710-3

Jensen, R. K., Pihl, R., Gadeberg, T. A. F., Jensen, J. K., Andersen, K. R., Thiel, S., Laursen, N. S. & Andersen, G. R. (2018). A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement. Journal of Biological Chemistry, 293(17), 6269-6281. https://doi.org/10.1074/jbc.RA117.001179

Rouvière, J. O., Bulfoni, M., Tuck, A., Cosson, B., Devaux, F. & Palancade, B. (2018). A SUMO-dependent feedback loop senses and controls the biogenesis of nuclear pore subunits. Nature Communications, 9, Article 1665. https://doi.org/10.1038/s41467-018-03673-3

Ntini, E., Louloupi, A., Liz, J., Muino, J. M., Marsico, A. & Ørom, U. A. V. (2018). Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin. Nature Communications, 9, Article 1636. https://doi.org/10.1038/s41467-018-04100-3

Mortensen, S. A., Sander, B., Jensen, R. K., Pedersen, J. S., Golas, M. M., Thiel, S. & Andersen, G. R. (2018). Models of the complement C1 complex. Proceedings of the National Academy of Sciences (PNAS), 115(17), E3866. Article E3866. https://doi.org/10.1073/pnas.1803577115

Hou, W., Nemitz, S., Schopper, S., Nielsen, M. L., Kessels, M. M. & Qualmann, B. (2018). Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl. Developmental Cell, 45(2), 262-275.e8. https://doi.org/10.1016/j.devcel.2018.03.007

Bertl, J., Guo, Q., Juul, M., Besenbacher, S., Nielsen, M. M., Hornshøj, H., Pedersen, J. S. & Hobolth, A. (2018). A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data. BMC Bioinformatics , 19(147), Article 147. https://doi.org/10.1186/s12859-018-2141-2

Rousselle, M., Mollion, M., Nabholz, B., Bataillon, T. & Galtier, N. (2018). Overestimation of the adaptive substitution rate in fluctuating populations. Biology Letters, 14(5), Article 20180055. https://doi.org/10.1098/rsbl.2018.0055

Taschner, M., Lorentzen, A., Mourão, A., Collins, T., Freke, G. M., Moulding, D., Basquin, J., Jenkins, D. & Lorentzen, E. (2018). Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis. eLife, 7, Article e33067. https://doi.org/10.7554/eLife.33067

Stenvang, M., Schafer, N. P., Malmos, K. G., Pérez, A.-M. W., Niembro, O., Sormanni, P., Basaiawmoit, R. V., Christiansen, G., Andreasen, M. & Otzen, D. E. (2018). Corneal dystrophy mutations drive pathogenesis by targeting TGFBIp stability and solubility in a latent amyloid-forming domain. Journal of Molecular Biology, 430(8), 1116-1140. https://doi.org/10.1016/j.jmb.2018.03.001

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