Peer-reviewed articles

Publications from the department

Journal covers made by researchers from our department

Latest peer-reviewed publications at MBG

Sort by: Date | Author | Title

Peer-reviewed publications at MBG - all years

Sort by: Date | Author | Title

Skinkyte-Juskiene, R., Kogelman, L. J. A. & Kadarmideen, H. N. (2018). Transcription factor co-expression networks of adipose RNA-Seq data reveal regulatory mechanisms of obesity. Current genomics, 19(4), 289-299. https://doi.org/10.2174/1389202918666171005095059

Harboe, M., Torvund-Jensen, J., Kjaer-Sorensen, K. & Laursen, L. S. (2018). Ephrin-A1-EphA4 signaling negatively regulates myelination in the central nervous system. Glia, 66(5), 934-950. https://doi.org/10.1002/glia.23293

Andersen, K. K., Vad, B. S., Kjaer, L., Tolker-Nielsen, T., Christiansen, G. & Otzen, D. E. (2018). Pseudomonas aeruginosa rhamnolipid induces fibrillation of human α-synuclein and modulates its effect on biofilm formation. FEBS Letters, 592(9), 1484-1496. https://doi.org/10.1002/1873-3468.13038

Cediel, G., Rueda, F., Oxvig, C., Oliveras, T., Labata, C., de Diego, O., Ferrer, M., Aranda-Nevado, M. C., Serra-Gregori, J., Núñez, J., García, C. & Bayes-Genis, A. (2018). Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction. Cardiovascular Diabetology, 17, Article 63. https://doi.org/10.1186/s12933-018-0710-3

Jensen, R. K., Pihl, R., Gadeberg, T. A. F., Jensen, J. K., Andersen, K. R., Thiel, S., Laursen, N. S. & Andersen, G. R. (2018). A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement. Journal of Biological Chemistry, 293(17), 6269-6281. https://doi.org/10.1074/jbc.RA117.001179

Rouvière, J. O., Bulfoni, M., Tuck, A., Cosson, B., Devaux, F. & Palancade, B. (2018). A SUMO-dependent feedback loop senses and controls the biogenesis of nuclear pore subunits. Nature Communications, 9, Article 1665. https://doi.org/10.1038/s41467-018-03673-3

Ntini, E., Louloupi, A., Liz, J., Muino, J. M., Marsico, A. & Ørom, U. A. V. (2018). Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin. Nature Communications, 9, Article 1636. https://doi.org/10.1038/s41467-018-04100-3

Mortensen, S. A., Sander, B., Jensen, R. K., Pedersen, J. S., Golas, M. M., Thiel, S. & Andersen, G. R. (2018). Models of the complement C1 complex. Proceedings of the National Academy of Sciences (PNAS), 115(17), E3866. Article E3866. https://doi.org/10.1073/pnas.1803577115

Bertl, J., Guo, Q., Juul, M., Besenbacher, S., Nielsen, M. M., Hornshøj, H., Pedersen, J. S. & Hobolth, A. (2018). A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data. BMC Bioinformatics , 19(147), Article 147. https://doi.org/10.1186/s12859-018-2141-2

Rousselle, M., Mollion, M., Nabholz, B., Bataillon, T. & Galtier, N. (2018). Overestimation of the adaptive substitution rate in fluctuating populations. Biology Letters, 14(5), Article 20180055. https://doi.org/10.1098/rsbl.2018.0055

Taschner, M., Lorentzen, A., Mourão, A., Collins, T., Freke, G. M., Moulding, D., Basquin, J., Jenkins, D. & Lorentzen, E. (2018). Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis. eLife, 7, Article e33067. https://doi.org/10.7554/eLife.33067

Stenvang, M., Schafer, N. P., Malmos, K. G., Pérez, A.-M. W., Niembro, O., Sormanni, P., Basaiawmoit, R. V., Christiansen, G., Andreasen, M. & Otzen, D. E. (2018). Corneal dystrophy mutations drive pathogenesis by targeting TGFBIp stability and solubility in a latent amyloid-forming domain. Journal of Molecular Biology, 430(8), 1116-1140. https://doi.org/10.1016/j.jmb.2018.03.001

Klinkhammer, J., Schnepf, D., Ye, L., Schwaderlapp, M., Gad, H. H., Hartmann, R., Garcin, D., Mahlakõiv, T. & Staeheli, P. (2018). IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission. eLife, 7, Article e33354. https://doi.org/10.7554/eLife.33354

Alonso, C., Fuertes, M., Martín-Encinas, E., Selas, A., Rubiales, G., Tesauro, C., Knudssen, B. K. & Palacios, F. (2018). Novel topoisomerase I inhibitors. Syntheses and biological evaluation of phosphorus substituted quinoline derivates with antiproliferative activity. European Journal of Medicinal Chemistry, 149, 225-237. https://doi.org/10.1016/j.ejmech.2018.02.058

Jordan, V. E., Walker, J. A., Beckstrom, T. O., Steely, C. J., McDaniel, C. L., St Romain, C. P., The Baboon Genome Analysis Consortium, Worley, K. C., Phillips-Conroy, J., Jolly, C. J., Rogers, J., Konkel, M. K. & Batzer, M. A. (2018). A computational reconstruction of Papio phylogeny using Alu insertion polymorphisms. Mobile DNA, 9(1), Article 13. https://doi.org/10.1186/s13100-018-0118-3

Stambler, I., jin, K., Lederman, S., Barzilai, N., Olshansky, S. J., Omokaro, E., Barratt, J., Anisimov, V., Rattan, S., Yang, S., Forster, M. & Byles, J. (2018). Aging Health and R&D for Healthy Longevity Must Be Included into the WHO Work Program. Aging and Disease, 9(2), 331-333. https://doi.org/10.14336/AD.2017.1120

Wong, A., Bryzek, D., Dobosz, E., Scavenius, C., Svoboda, P., Rapala-Kozik, M., Lesner, A., Frydrych, I., Enghild, J., Mydel, P., Pohl, J., Thompson, P. R., Potempa, J. & Koziel, J. (2018). A Novel Biological Role for Peptidyl-Arginine Deiminases: Citrullination of Cathelicidin LL-37 Controls the Immunostimulatory Potential of Cell-Free DNA. Journal of Immunology, 200(7), 2327-2340. https://doi.org/10.4049/jimmunol.1701391

He, F., Bhoobalan-Chitty, Y., Van, L. B., Kjeldsen, A. L., Dedola, M., Makarova, K. S., Koonin, E. V., Brodersen, D. E. & Peng, X. (2018). Anti-CRISPR proteins encoded by archaeal lytic viruses inhibit subtype I-D immunity. Nature Microbiology, 3(4), 461-469. https://doi.org/10.1038/s41564-018-0120-z

Greve, A. N., Jepsen, J. R. M., Mortensen, E. L., Uher, R., Mackenzie, L., Foldager, L., Gantriis, D. L. L., Burton, B. K., Ellersgaard, D. V., Christiani, C. J., Spang, K. S., Hemager, N., Henriksen, M. T., Zahle, K. K., Stadsgaard, H. B., Thorup, A. A. E., Nordentoft, M., Plessen, K., Mors, O. & Bliksted, V. F. (2018). Associations between intelligence, verbal working memory and processing speed in parents with schizophrenia or bipolar disorder and their 7-year old offspring. Schizophrenia Bulletin, 44(Suppl_1), S252-S252.

Kaadt, E., Mumm, B. H., Andersen, S. N., Damgaard, C. K. & Elfving, B. (2018). Biomarkers of depression in skin - a novel approach. 1:1-23 (page 15). Abstract from SCNP - 2018, Aarhus.

Ernst, E. H., Franks, S., Hardy, K., Villesen, P. & Lykke-Hartmann, K. (2018). Granulosa cells from human primordial and primary follicles show differential global gene expression profiles. Human Reproduction, 33(4), 666-679. https://doi.org/10.1093/humrep/dey011

Østergaard, S. D., Foldager, L., Mors, O., Beck, P. & Correll, C. U. (2018). The validity and sensitivity of PANSS-6 in treatment-resistant schizophrenia. Schizophrenia Bulletin, 44(Suppl_1), S341-S342.

Hjortebjerg, R., Berryman, D. E., Comisford, R., List, E. O., Oxvig, C., Bjerre, M., Frystyk, J. & Kopchick, J. J. (2018). Depot-specific and GH-dependent regulation of IGF binding protein-4, pregnancy-associated plasma protein-A, and stanniocalcin-2 in murine adipose tissue. Growth Hormone & IGF Research, 39, 54-61. https://doi.org/10.1016/j.ghir.2018.01.001

Alsved, M., Holm, S., Christiansen, S., Smidt, M., Rosati, B., Ling, M., Boesen, T., Finster, K., Bilde, M., Löndahl, J. & Šantl-Temkiv, T. (2018). Corrigendum: Effect of aerosolization and drying on the viability of pseudomonas syringae cells (Front. Microbiol) 9, 3086, (10.3389/fmicb.2018.03086). Frontiers in Microbiology, 10(OCT), Article 2378. https://doi.org/10.3389/fmicb.2019.02378

Alsved, M., Holm, S., Christiansen, S., Smidt, M., Ling, M., Boesen, T., Finster, K., Bilde, M., Londahl, J. & Santl-Temkiv, T. (2018). Effect of Aerosolization and Drying on the Viability of Pseudomonas syringae Cells. Frontiers in Microbiology, 9, Article 3086. https://doi.org/10.3389/fmicb.2018.03086

Hannon, E., Schendel, D., Ladd-Acosta, C., Grove, J., Hansen, C. S., Andrews, S. V., Hougaard, D. M., Bresnahan, M., Mors, O., Hollegaard, M. V., Bækvad-Hansen, M., Hornig, M., Mortensen, P. B., Børglum, A. D., Werge, T., Pedersen, M. G., Nordentoft, M., Buxbaum, J., Daniele Fallin, M. ... iPSYCH-Broad ASD Group (Mette Nyegaard, Per Qvist, Jane Hvarregaard Christensen - members of -) (2018). Elevated polygenic burden for autism is associated with differential DNA methylation at birth. Genome Medicine, 10(1), Article 19. https://doi.org/10.1186/s13073-018-0527-4

The Baboon Genome Analysis Consortium (2018). Analysis of lineage-specific Alu subfamilies in the genome of the olive baboon, Papio anubis. Mobile DNA, 9(1), Article 10. https://doi.org/10.1186/s13100-018-0115-6

the iPSYCH-Broad autism group & the 23andMe Research Team (2018). Genome-wide analyses of self-reported empathy: Correlations with autism, schizophrenia, and anorexia nervosa. Translational Psychiatry, 8(1), Article 35. https://doi.org/10.1038/s41398-017-0082-6

Song, W., Yang, C., Svend Le, D. Q., Zhang, Y. & Kjems, J. (2018). Calcium-microRNA Complexes Functionalized Nanotubular Implant Surface for Highly Efficient Transfection and Enhanced Osteogenesis of Mesenchymal Stem Cells. A C S Applied Materials and Interfaces, 10(9), 7756-7764. https://doi.org/10.1021/acsami.7b18289

Kjeldsen, E., Nielsen, C. J. F., Roy, A., Tesauro, C., Jakobsen, A.-K., Stougaard, M. & Knudsen, B. R. (2018). Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5. Cancer Genomics & Proteomics, 15(2), 91-114. https://doi.org/10.21873/cgp.20068

Manav, M. C., Beljantseva, J., Bojer, M. S., Tenson, T., Ingmer, H., Hauryliuk, V. & Brodersen, D. E. (2018). Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP. Journal of Biological Chemistry, 293(9), 3254-3264. https://doi.org/10.1074/jbc.RA117.001374

Bussey, K. A., Lau, U., Schumann, S., Gallo, A., Osbelt, L., Stempel, M., Arnold, C., Wissing, J., Gad, H. H., Hartmann, R., Brune, W., Jänsch, L., Whitehouse, A. & Brinkmann, M. M. (2018). The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi’s sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein. PLoS Pathogens, 14(3), Article e1006937. https://doi.org/10.1371/journal.ppat.1006937

Zhang, M., Lykke-Andersen, S., Zhu, B., Xiao, W., Hoskins, J. W., Zhang, X., Rost, L. M., Collins, I., Bunt, M. V. D., Jia, J., Parikh, H., Zhang, T., Song, L., Jermusyk, A., Chung, C. C., Zhu, B., Zhou, W., Matters, G. L., Kurtz, R. C. ... Amundadottir, L. (2018). Characterising cis-regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues. Gut, 67(3), 521-533. https://doi.org/10.1136/gutjnl-2016-313146

Stoll, L., Sobel, J., Rodriguez-Trejo, A., Guay, C., Lee, K., Venø, M. T., Kjems, J., Laybutt, D. R. & Regazzi, R. (2018). Circular RNAs as novel regulators of β-cell functions in normal and disease conditions. Molecular Metabolism, 9, 69-83. https://doi.org/10.1016/j.molmet.2018.01.010

Bouwman, A. C., Daetwyler, H. D., Chamberlain, A. J., Ponce, C. H., Sargolzaei, M., Schenkel, F. S., Sahana, G., Govignon-Gion, A., Boitard, S., Dolezal, M., Pausch, H., Brøndum, R. F., Bowman, P. J., Thomsen, B., Guldbrandtsen, B., Lund, M. S., Servin, B., Garrick, D. J., Reecy, J. ... Hayes, B. J. (2018). Meta-analysis of genome-wide association studies for cattle stature identifies common genes that regulate body size in mammals. Nature Genetics, 50(3), 362-372. https://doi.org/10.1038/s41588-018-0056-5

Palkopoulou, E., Lipson, M., Mallick, S., Nielsen, S., Rohland, N., Baleka, S., Karpinski, E., Ivancevic, A. M., To, T.-H., Kortschak, R. D., Raison, J. M., Qu, Z., Chin, T.-J., Alt, K. W., Claesson, S., Dalén, L., MacPhee, R. D. E., Meller, H., Roca, A. L. ... Reich, D. (2018). A comprehensive genomic history of extinct and living elephants. Proceedings of the National Academy of Sciences (PNAS), 115(11), E2566-E2574. https://doi.org/10.1073/pnas.1720554115

Rattan, S., Demirovic, D. & Nizard, C. (2018). A preliminary attempt to establish multiple stress response profiles of human skin fibroblasts exposed to mild or severe stress during ageing in vitro. Mechanisms of Ageing and Development, 170(March), 92-97. https://doi.org/10.1016/j.mad.2017.09.005

Prabha, R. D., Kraft, D. C. E., Harkness, L., Melsen, B., Varma, H., Nair, P. D., Kjems, J. & Kassem, M. (2018). Bioactive Nano-fibrous Scaffold for Vascularized Craniofacial Bone Regeneration. Journal of Tissue Engineering and Regenerative Medicine, 12(3), e1537-e1548. https://doi.org/10.1002/term.2579

GERAD1 Consortium: (2018). Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 50(3), 381-389. https://doi.org/10.1038/s41588-018-0059-2