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Department of Molecular Biology and Genetics

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Latest peer-reviewed publications at MBG

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Displaying results 4201 to 62 out of 62

Peer-reviewed publications at MBG - all years

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Laursen, K. B., Mielke, E., Iannaccone, P. & Füchtbauer, E.-M. (2007). Mechanism of transcriptional activation by the proto-oncogene twist1. Journal of Biological Chemistry, 282, 34623-34633.

Fedosov, S., Fedosova, N. U., Kräutler, B., Nexø, E. & Petersen, T. E. (2007). Mechanisms of discrimination between cobalamins and their natural analoques during their binding to the specific B₁₂-transporting proteins. Biochemistry, 46(21), 6446-6458.

Desler, C., Munch-Petersen, B., Stevnsner, T. V., Matsui, S.-I., Kulawiec, M., Singh, K. & Rasmussen, L. J. (2007). Mitochondria as determinant of nucleotide metabolism and chromosomal stability. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 625, 112-124. https://doi.org/10.1016/j.mrfmmm.2007.06.002

Sehgal, P., Bang Nielsen, S., Pedersen, S., Wimmer, R. & Otzen, D. (2007). Modulation of cutinase structure and stability by phospholipid detergents. Biochim. Biophys. Acta., (1774), 1544-1554.

Howard, K. A., Dong, M., Oupicky, D., Bisht, H. S., Buss, C., Besenbacher, F. & Kjems, J. (2007). Nanocarrier stimuli-activated gene delivery. Small, 3(1), 54-7. https://doi.org/10.1002/smll.200600328

Nielsen, A. F., Leuschner, P. J. F. & Martinez, J. (2007). Not miR-ly a splicing factor: hnRNP A1 succumbs to microRNA temptation. Nature Structural and Molecular Biology, 14(7), 572-3. https://doi.org/10.1038/nsmb0707-572

Kehlet, C., Bjerring, M., Sivertsen, A. C., Kristensen, T., Enghild, J. J., Glaser, S. J., Khaneja, N. & Nielsen, N. C. (2007). Optimal control based NCO and NCA experiments for spectral assignment in biological solid-state NMR spectroscopy. Journal of Magnetic Resonance, 188(2), 216-230. https://doi.org/10.1016/j.jmr.2007.06.011

Agnholt, J., Kelsen, J., Schack, L., Hvas, C. L., Dahlerup, J. F. & Sørensen, E. S. (2007). Osteopontin, a protein with cytokine-like properties, is associated with inflammation in Crohn's disease. Scand. J. Immunol., 65, 453-60.

Lykke-Andersen, S. & Jensen, T. H. (2007). Overlapping pathways dictate termination of RNA polymerase II transcription: RNA polymerase II termination. Biochimie, 89(10), 1177-1182.

Møller, I. M., Jensen, P. E. & Hansson, A. (2007). Oxidative Modifications to Cellular Components in Plants. Annual Review of Plant Physiology and Plant Molecular Biology, 58, 459-481. https://doi.org/10.1146/annurev.arplant.58.032806.103946

Song, Y. J. C., Lundvig, D. M. S., Huang, Y., Gai, W. P., Blumbergs, P. C., Højrup, P., Otzen, D., Halliday, G. M. & Jensen, P. H. (2007). p25a Relocalizes in Oligodendroglia from Myelin to Cytoplasmic Inclusions in Multiple System Atrophy. Am. J. Path., (171), 1291-1303.

Skivesen, N., Têtu, A., Kristensen, M., Kjems, J., Frandsen, L. H. & Borel, P. I. (2007). Photonic-crystal waveguide biosensor. Optics Express, 15(6), 3169-3176.

Howard, K. A. & Kjems, J. (2007). Polycation-based nanoparticle delivery for improved RNA interference therapeutics. Expert opinion on biological therapy, 7(12), 1811-1822. https://doi.org/10.1517/14712598.7.12.1811

Howard, K. A. & Kjems, J. (2007). Polycation-based nanoparticle delivery for improved RNAi therapeutics. Expert Opin. Biol. Ther, 7, 1811-1822.

Gododkin, J., Cirera, S., Hedegaard, J., Gilchrist, M. J., Panitz, F., Jørgensen, C., Scheibye-Knudsen, K., Arvin, T., Lumholdt, S., Sawera, M., Green, T., Nielsen, B. J., Havgaard, J. H., Rosenkilde, C., Wang, J., Li, H., Li, R., Liu, B., Hu, S. ... Fredholm, M. (2007). Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags. Genome Biology (Online Edition), 8(4), R45. https://doi.org/10.1186/gb-2007-8-4-r45

Wæhrens, L. N., Rasmussen, J. T., Heegaard, C. W. & Falborg, L. (2007). Preparation and in vitro evaluation of 99mTc-labelled bovine lactadherin as a novel radioligand for apoptosis detection. Journal of Labelled Compounds and Radiopharmaceuticals, 50, 211.

Gendron, C., Kashiwagi, M., Lim, N. H., Enghild, J. J., Thøgersen, I., Hughes, C., Catherson, B. & Nagase, H. (2007). Proteolytic activities of human ADAMTS-5: Comparative studies with human ADAMTS-4. Journal of Biological Chemistry.

Bisgaard, C., Jayatissa, M. N., Enghild, J. J., Sanchéz, C., Artemychyn, R. & Wiborg, O. (2007). Proteomic investigation of the ventral rat hippocampus links DRP-2 to escitalopram treatment resistance and SNAP to stress resilience in the chronic mild stress model of depression. Journal of Molecular Neuroscience, 32(2), 132-44.

Arendt, M., Rosenberg, R., Foldager, L., Perto, G. & Munk-Jørgensen, P. (2007). Psychopathology among cannabis-dependent treatment seekers and association with later substance abuse treatment. Journal of Substance Abuse Treatment, 32(2), 113-119.

Addison, W. N., Azari, F., Sørensen, E. S., Kaartinen, M. T. & McKee, M. D. (2007). Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, upregulating osteopontin and inhibiting alkaline phosphatase actvity. Journal of Biological Chemistry, 282, 15872-15883.

Nielsen, C. G., Christiansen, M. & Oxvig, C. (2007). Quantification of proteolytically active pregnancy-associated plasma protein-A using an assay based on quenched fluorescence. Clinical chemistry, 53, 947-954.

Nielsen, C. G. & Oxvig, C. (2007). Quantitative analysis of insulin-like growth factor (IGF) modulated proteolysis of IGF binding protein-4 and -5 by pregnancy-associated plasma protein-A. Biochemistry, 46, 1982-80.

Hovgaard, M. B., Dong, M., Otzen, D. E. & Besenbacher, F. (2007). Quartz crystal microbalance studies of multilayer glucagon fibrillation at the solid-liquid interface. Biophysical Journal, 93(6), 2162-9. https://doi.org/10.1529/biophysj.107.109686

Hovgaard, M. B., Dong, M., Otzen, D. & Besenbacher, F. (2007). Quartz crystal microbalance studies of multilayer glucagons fibrillation at the solid-liquid interface. Biophysical Journal, 93(6), 2162.

Thaysen-Andersen, M., Thøgersen, I., Nielsen, HJ., Lademann, U., Brunner, N., Enghild, J. J. & Højrup, P. (2007). Rapid and individual-specific glycoprofiling of a low- abundant N-glycosylated protein tissue inhibitor of metalloproteinases-1. Mol. Cell. Proteomics.

Laursen, L. S., Kjær-Sørensen, K., Andersen, M. H. & Oxvig, C. (2007). Regulation of insulin-like growth factor (IGF) bioactivity by sequential proteolytic cleavage of IGF binding protein-4 and -5. Molecular Endocrinology, 21(5), 1246-1257.

Blechingberg, J., Lykke-Andersen, S., Jensen, T. H., Jørgensen, A. L. & Nielsen, A. L. (2007). Regulatory mechanisms for 3'-end alternative splicing and polyadenylation of the Glial Fibrillary Acidic Protein, GFAP, transcript. Nucleic Acids Research, 35(22), 7636-50. https://doi.org/10.1093/nar/gkm931

Hede, M. S., Petersen, R. L., Krüger, D., Andersen, F. F., Andersen, A. H. & Knudsen, B. R. (2007). Resolution of Holliday junction substrates by human topoisomerase I. Journal of Molecular Biology.

Andersen, E. S., Lind-Thomsen, A., Knudsen, B., Kristensen, S. E., Havgaard, J. H., Torarinsson, E., Larsen, N., Zwieb, C., Sestoft, P., Kjems, J. & Gorodkin, J. (2007). Semiautomated improvement of RNA alignments. RNA, 13, 1850-1859.

Panitz, F., Stengaard, H., Hornshøj, H., Gorodkin, J., Hedegaard, J., Cirera, S., Thomsen, B., Madsen, L. B., Høj, A., Vingborg, R., Bujie, Z., Wang, X., Wang, X. F., Wernersson, R., Jørgensen, C. B., Scheibye-Knudsen, K., Arvin, T., Lumholdt, S., Sawera, M. ... Bendixen, C. (2007). SNP mining porcine ESTs with MAVIANT, a novel tool for SNP evaluation and annotation. Bioinformatics, 23(13), i387-i391. https://doi.org/10.1093/bioinformatics/btm192

Søe, R., Mosley, R. T., Justice, M., Nielsen-Kahn, J., Shastry, M., Merrill, A. R. & Andersen, G. R. (2007). Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2. Journal of Biological Chemistry, 282, 657-666.

Washietl, S., Pedersen, J. S., Korbel, J. O., Stocsits, C., Gruber, A. R., Hackermüller, J., Hertel, J., Lindemeyer, M., Reiche, K., Tanzer, A., Ucla, C., Wyss, C., Antonarakis, S. E., Denoeud, F., Lagarde, J., Drenkow, J., Kapranov, P., Gingeras, T. R., Guigó, R. ... Stadler, P. F. (2007). Structured RNAs in the ENCODE selected regions of the human genome. Genome Research, 17(6), 852-64. https://doi.org/10.1101/gr.5650707

Berge, U., Behrens, J. & Rattan, S. (2007). Sugar-induced premature aging and altered differentiation in human epidermal keratinocytes. New York Academy of Sciences. Annals, 1100, 524-529.

Fedosov, S., Berglund, L. E., Nexø, E. & Petersen, T. E. (2007). Tetrazole derivatives and matrices as novel cobalamin coordinating compounds. J. Organometallic Chem., 692, 1234-1242.

Jonstrup, A. T., Andersen, K. R., Van, L. B. & Brodersen, D. E. (2007). The 1.4-Å crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzyme. Nucleic Acids Research, 35(9), 3153-3164. https://doi.org/10.1093/nar/gkm178

Andersen, S. U., Algreen-Petersen, R. G., Hödl, M., Jurkiewicz, A., Cvitanich, C., Braunschweig, U., Schauser, L., Oh, S.-A., Twell, D. & Jensen, E. Ø. (2007). The conserved cysteine-rich domain of a tesmin/TSO1-like protein binds zinc in vitro and TSO1 is required for both male and female fertility in Arabidopsis thaliana. Journal of Experimental Botany, 58, 3657-3670. https://doi.org/10.1093/jxb/erm215

Lykke-Andersen, S., Piñol-Roma, S. & Kjems, J. (2007). The human ADAR1 transcripts contain an alternative retained intron within a region that functions both as a 5'UTR and an ORF. RNA, 89(10).

Liu, X., Howard, K. A., Dong, M., Andersen, M. Ø., Rahbek, U. L., Johnsen, M. G., Hansen, O. C., Besenbacher, F. & Kjems, J. (2007). The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing. Biomaterials, 28(6), 1280-8. https://doi.org/10.1016/j.biomaterials.2006.11.004

Valnickova, Z., Thøgersen, I., Potempa, J. & Enghild, J. J. (2007). The intrinsic enzymatic activity of procarboxypeptidase U (TAFI) does not significantly influence the fibrinolytic rate: reply to a rebuttal. J Thromb Haemost. 2007.

Morgensen, JE., Ferreras, M., Wimmer, R., Petersen, S. V., Enghild, J. J. & Otzen, D. (2007). The Major Allergen from Birch Tree Pollen, Bet v 1, Binds and Permeabilizes Membranes. Biochemistry.

Rattan, S. (2007). The science of healthy aging: genes, milieu, and chance. New York Academy of Sciences. Annals, 1114, 1-10.

Olesen, C., Picard, M., Winther, A.-M. L., Nielsen, C. G., Morth, J. P., Oxvig, C., Møller, J. V. & Nissen, P. (2007). The structural basis of calcium transport by the calcium pump. Nature, 450(7172), 1036-1042. https://doi.org/10.1038/nature06418

Petersen, S. V., Valnickova, Z., Oury, T. D., Crapo, J. D., Nielsen, N. C. & Enghild, J. J. (2007). The Subunit Composition of Human Extracellylar Superoxide Dismutate (EC-SOD) Regulate Enzymatic Activity. BMC Biochemistry, 8, 19.

Kuhn, R. M., Karolchik, D., Zweig, A. S., Trumbower, H., Thomas, D. J., Thakkapallayil, A., Sugnet, C. W., Stanke, M., Smith, K. E., Siepel, A., Rosenbloom, K. R., Rhead, B., Raney, B. J., Pohl, A., Pedersen, J. S., Hsu, F., Hinrichs, A. S., Harte, R. A., Diekhans, M. ... Pedersen, J. S. (2007). The UCSC genome browser database: update 2007. Nucleic Acids Research, 35(Database issue), D668-73. https://doi.org/10.1093/nar/gkl928

Valnickova, Z., Thøgersen, I., Potempa, J. & Enghild, J. J. (2007). Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase. Journal of Biological Chemistry, 282(2), 1072-9.

Barciszewska, M., Barciszewska, A. M. & Rattan, S. (2007). TLC-based detection of methylated cytosine: application to aging epigenetics. Biogerontology, 8(6), 673-678.

Novotny, G. W., Sonne, S., Nielsen, J. E., Jonstrup, S. P., Hansen, M. A., Skakkebaek, N. E., Rajpert-De Meyts, E., Kjems, J. & Leffers, H. (2007). Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster. Cell Death and Differentiation, 14(4), 879-882. https://doi.org/10.1038/sj.cdd.4402090

Leppälä, J., Bechsgaard, J. S., Schierup, M. H. & Savolainen, O. (2007). Transmission ratio distortion in Arabidopsis lyrata: effects of population divergence and the S-locus. Heredity, 100(1), 71-8. https://doi.org/10.1038/sj.hdy.6801066

Frøhlich, R. F., Veigaard, C., Andersen, F. F., McClendon, A. K., Gentry, A. K., Andersen, A. H., Osherroff, N., Stevnsner, T. V. & Knudsen, B. R. (2007). Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal. Nucleic Acid Res., 35, 6170-6180.

Nielsen, M. M., Andersen, K. K., Westh, P. & Otzen, D. (2007). Unfolding of ß-sheet proteins in SDS. Biophysical Journal, (92), 3674-3685.

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