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Latest peer-reviewed publications at MBG

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Displaying results 2901 to 136 out of 136

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Erikstrup, L. T., Aarup, M., Hagemann-Madsen, R., Dagnaes-Hansen, F., Kristensen, B., Olsen, K. E. P. & Fuursted, K. (2015). Treatment of Clostridium difficile infection in mice with vancomycin alone is as effective as treatment with vancomycin and metronidazole in combination. BMJ Open Gastroenterology, 2(1), e000038. https://doi.org/10.1136/bmjgast-2015-000038

Ahn, B., Stevnsner, T. & Bohr, V. A. (2015). Werner syndrome: Association of premature aging and cancer predisposition. In E. P. Gelmann, C. L. Sawyers & F. J. Rauscher, III (Eds.), Molecular Oncology: Causes of Cancer and Targets for Treatment (pp. 423-433). Cambridge University Press. https://doi.org/10.1017/CBO9781139046947.036

Penner, R., Andersen, E. S., Jensen, J. L., Kantcheva, A. K., Bublitz, M., Nissen, P., Rasmussen, A. M. H., Svane, K. L., Hammer, B., Rezazadegan, R., Nielsen, N. C., Nielsen, J. T. & Andersen, J. E. (2014). Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture. Nature Communications, 5, Article 5803. https://doi.org/10.1038/ncomms6803

Jurkin, J., Henkel, T., Nielsen, A. F., Minnich, M., Popow, J., Kaufmann, T., Heindl, K., Hoffmann, T., Busslinger, M. & Martinez, J. (2014). The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells. EMBO Journal, 33(24), 2922-36. https://doi.org/10.15252/embj.201490332

Neumann, J., Klein, N., Otzen, D. & Schneider, D. (2014). Folding energetics and oligomerization of polytopic α-helical transmembrane proteins. Archives of Biochemistry and Biophysics, 564, 281–296. https://doi.org/10.1016/j.abb.2014.07.017

Otzen, D. (2014). Membrane protein folding and stability. Archives of Biochemistry and Biophysics, 564, 262-264. https://doi.org/10.1016/j.abb.2014.10.014

Ibsen, M. S., Gad, H. H., Thavachelvam, K., Boesen, T., Desprès, P. & Hartmann, R. (2014). The 2'-5'-Oligoadenylate Synthetase 3 Enzyme Potently Synthesizes the 2'-5'-Oligoadenylates Required for RNase L Activation. Journal of Virology, 88(24), 14222-14231. https://doi.org/10.1128/JVI.01763-14

Jarvis, E. D., Mirarab, S., Aberer, A. J., Li, B., Houde, P., Li, C., Ho, S. Y. W., Faircloth, B. C., Nabholz, B., Howard, J. T., Suh, A., Weber, C. C., da Fonseca, R. R., Li, J., Zhang, F., Li, H., Zhou, L., Narula, N., Liu, L. ... Zhang, G. (2014). Whole-genome analyses resolve early branches in the tree of life of modern birds. Science, 346(6215), 1320-31. https://doi.org/10.1126/science.1253451

De Orué Lucana, D. O., Fedosov, S. N., Wedderhoff, I., Che, E. N. & Torda, A. E. (2014). The extracellular heme-binding protein hbps from the soil bacterium Streptomyces reticuli is an aquo-cobalamin binder. Journal of Biological Chemistry, 289(49), 34214-34228. https://doi.org/10.1074/jbc.M114.585489

Pedersen, H. S., Løvendahl, P., Larsen, K. E., Madsen, L. B. & Callesen, H. (2014). mtDNA copy number in oocytes of different sizes from individual pre- and post-pubertal pigs. Reproduction, Fertility and Development, 27(1), 181-182. Article (abst 181). https://doi.org/10.1071/RDv27n1Ab181

Ferreira, J. B., Pimentel, L., Keasey, M. P., Lemos, R. R., Santos, L. M., Oliveira, M. F., Santos, S., Jensen, N., Teixeira, K., Pedersen, L., Rocha, C. R., Dias da Silva, M. R. & Oliveira, J. R. M. (2014). First Report of a De Novo Mutation at SLC20A2 in a Patient with Brain Calcification. Journal of Molecular Neuroscience, 54(4), 748-751. https://doi.org/10.1007/s12031-014-0357-9

Mourao, A., Nager, A. R., Nachury, M. V. & Lorentzen, E. (2014). Structural basis for membrane targeting of the BBSome by ARL6. Nat. Struct. Mol. Biol., 21(12), 1035-1041.

Kaalund, S. S., Venø, M. T., Bak, M., Møller, R. S., Laursen, H., Madsen, F., Broholm, H., Quistorff, B., Uldall, P., Tommerup, N., Kauppinen, S., Sabers, A., Fluiter, K., Møller, L. B., Nossent, A. Y., Silahtaroglu, A., Kjems, J., Aronica, E. & Tümer, Z. (2014). Aberrant expression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal sclerosis-Convergence on axonal guidance. Epilepsia, 55(12), 2017-2027. https://doi.org/10.1111/epi.12839

Andersen, K. K. & Otzen, D. (2014). Denaturation of α-lactalbumin and myoglobin by the anionic biosurfactant rhamnolipid. Biochimica et biophysica acta. Bioenergeticss, 1844(12), 2338-2345. https://doi.org/10.1016/j.bbapap.2014.10.005

Kaspersen, J. D., Pedersen, J. N., Hansted, J. G., Nielsen, S. B., Sakthivel, S., Wilhelm, K., Nemashkalova, E. L., Permyakov, S. E., Permyakov, E. A., Pinto Oliveira, C. L., Morozova-Roche, L. A., Otzen, D. & Pedersen, J. S. (2014). Generic Structures of Cytotoxic Liprotides: Nano-Sized Complexes with Oleic Acid Cores and Shells of Disordered Proteins. ChemBioChem, 10(18), 2693-2702. https://doi.org/10.1002/cbic.201402407

Grove, J., Børglum, A. & Pearce, B. D. (2014). GWAS, Cytomegalovirus Infection, and Schizophrenia. Current Behavioral Neuroscience Reports, 1(4), 215-223. https://doi.org/10.1007/s40473-014-0022-1

Blanquart, F., Achaz, G., Bataillon, T. & Tenaillon, O. (2014). Properties of selected mutations and genotypic landscapes under Fisher's geometric model. Evolution, 68(12), 3537-54. https://doi.org/10.1111/evo.12545

Hyldgaard, M., Mygind, T., Vad, B. S., Stenvang, M., Otzen, D. & Meyer, R. L. (2014). The Antimicrobial Mechanism of Action of Epsilon-Poly-L-Lysine. Applied and Environmental Microbiology, 80(24), 7758-7770 . https://doi.org/10.1128/AEM.02204-14

Lykke-Andersen, S., Chen, Y., Ardal, B., Lilje, B., Waage, J. E., Sandelin, A. G. & Jensen, T. H. (2014). Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes. Genes & Development, 28(22), 2498-2517. https://doi.org/10.1101/gad.246538.114

Knudsen, M., Søndergaard, D. & Pedersen, C. N. S. (2014). Combinatorics of Non-Ribosomal Peptide Synthetases.

Ottaviani, A., Tesauro, C., Fjelstrup, S., Hougaard, R. F., Fiorani, P., Desideri, A., Knudsen, B. R. & Ho, Y.-P. (2014). Extraction of Active Enzymes from "Hard-to-Break-Cells": Evaluation by a RCA-based Assay. Paper presented at IEEE Sensors 2014, Valencia, Spain. http://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=6985363

Malinauskaite, L., Quick, M., Reinhard, L., Lyons, J. A., Yano, H., Javitch, J. A. & Nissen, P. (2014). A mechanism for intracellular release of Na(+) by neurotransmitter/sodium symporters. Nature Structural and Molecular Biology, 21(11), 1006-1012. https://doi.org/10.1038/nsmb.2894

Koro, C., Bielecka, E., Dahl-Knudsen, A., Enghild, J. J., Scavenius, C., Brun, J. G., Binder, V., Hellvard, A., Bergum, B., Jonsson, R., Potempa, J., Blom, A. M. & Mydel, P. (2014). Carbamylation of immunoglobulin abrogates activation of the classical complement pathway. European Journal of Immunology, 44(11), 3403-3412. https://doi.org/10.1002/eji.201444869

Eller, F., Lambertini, C., Nielsen, M. W., Radutoiu, S. & Brix, H. (2014). Expression of major photosynthetic and salt-resistance genes in invasive reed lineages grown under elevated CO₂ and temperature. Ecology and Evolution, 4(21), 4161-4172. https://doi.org/10.1002/ece3.1282

Christensen, B., Zachariae, E. D., Scavenius, C., Thybo, M., Callesen, M. M., Kløverpris, S., Oxvig, C., Enghild, J. J. & Sørensen, E. S. (2014). Identification of transglutaminase reactive residues in human osteopontin and their role in polymerization. PLoS One, 9(11), Article e113650. https://doi.org/10.1371/journal.pone.0113650

Søndergaard, D., Knudsen, M. & Pedersen, C. N. S. (2014). Machine learning approaches to functional prediction of P-Type ATPases.

Bykova, N. V., Møller, I. M., Gardeström, P. & Igamberdiev, A. U. (2014). The function of glycine decarboxylase complex is optimized to maintain high photorespiratory flux via buffering of its reaction products. Mitochondrion, 19(B), 357-364. https://doi.org/10.1016/j.mito.2014.01.001

Mansfield, A. S., Visscher, D. W., Hart, S. N., Wang, C., Goetz, M. P., Oxvig, C. & Conover, C. A. (2014). Pregnancy-associated plasma protein-A expression in human breast cancer. Growth Hormone and IGF Research, 24(6), 264-267. https://doi.org/10.1016/j.ghir.2014.10.007

Wang, K., Sitsel, O., Meloni, G., Autzen, H. E., Andersson, M., Klymchuk, T., Nielsen, A. M., Rees, D. C., Nissen, P. & Gourdon, P. (2014). Structure and mechanism of Zn²⁺-transporting P-type ATPases. Nature, 514(7523), 518-522. https://doi.org/10.1038/nature13618

Andreasen, M., Skeby, K. K., Zhang, S., Nielsen, E. H., Klausen, L. H., Frahm, H., Christiansen, G., Skrydstrup, T., Dong, M., Schiøtt, B. & Otzen, D. (2014). The Importance of Being Capped: Terminal Capping of an Amyloidogenic Peptide Affects Fibrillation Propensity and Fibril Morphology. Biochemistry, 53(44), 6968-6980. https://doi.org/10.1021/bi500674u

Behrens, M. A., Sendall, T. J., Pedersen, J. S., Kjeldgaard, M., Huntington, J. A. & Jensen, J. K. (2014). The Shapes of Z-α1-Antitrypsin Polymers in Solution Support the C-Terminal Domain-Swap Mechanism of Polymerization. Biophysical Journal, 107(8), 1905-1912. https://doi.org/10.1016/j.bpj.2014.08.030

Bielecka, E., Scavenius, C., Kantyka, T., Jusko, M., Mizgalska, D., Szmigielski, B., Potempa, B., Enghild, J. J., Prossnitz, E., Blom, A. M. & Potempa, J. (2014). Peptidyl arginine deiminase from Porphyromonas gingivalis abolishes C5a activity. Journal of Biological Chemistry, 289, 32481-32487. https://doi.org/10.1074/jbc.C114.617142

Foldager, L., Als, T. D. & Grove, J. (2014). Comparing methods for genome-wide gene-environment interaction analysis.

Lindgreen, S., Krogh, A. & Pedersen, J. S. (2014). SNPest: a probabilistic graphical model for estimating genotypes. BMC Research Notes, 7, 698. https://doi.org/10.1186/1756-0500-7-698

Taschner, M., Kotsis, F., Braeuer, P., Kuehn, E. W. & Lorentzen, E. (2014). Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly. European Journal of Cell Biology, 207(2), 269-282.

Jacobsen, L. M. W., Pujolar, J. M., Bernatchez, L., Munch, K., Jian, J., Niu, Y. & Hansen, M. M. (2014). Genomic footprints of speciation in Atlantic eels (Anguilla anguilla and A. Rostrata). Molecular Ecology, 23(19), 4785-4798. https://doi.org/10.1111/mec.12896

Yang, C., Gao, S. & Kjems, J. (2014). Folic Acid Conjugated Chitosan for Targeted Delivery of siRNA to Activated Macrophages in vitro and in vivo. Journal of Materials Chemistry B, 48, 8608-8615. https://doi.org/10.1039/C4TB01374C

Holm, E., Gleberzon, J. S., Liao, Y., Sørensen, E. S., Beier, F., Hunter, G. K. & Hunter, G. K. (2014). Osteopontin mediates mineralization and not osteogenic cell development in vitro. Biochemical Journal, 464(3), 355-364. https://doi.org/10.1042/BJ20140702

Larsen, K. E., Momeni, J., Farajzadeh, L. & Bendixen, C. (2014). Porcine SLITRK1: Molecular cloning and characterization. F E B S Open Bio, 4, 872-878. https://doi.org/10.1016/j.fob.2014.10.001

Kogelman, L. J. A., Cirera, S., Zhernakova, D. V., Fredholm, M., Franke, L. & Kadarmideen, H. N. (2014). Identification of co-expression gene networks, regulatory genes and pathways for obesity based on adipose tissue RNA Sequencing in a porcine model. BMC Medical Genomics, 7(1), Article 57. https://doi.org/10.1186/1755-8794-7-57

Ostenfeld, M. S., Jeppesen, D. K., Laurberg, J. R., Boysen, A. T., Bramsen, J. B., Primdal-Bengtson, B., Hendrix, A., Lamy, P., Dagnaes-Hansen, F., Rasmussen, M. H., Bui, K. H., Fristrup, N., Christensen, E. I., Nordentoft, I., Morth, J. P., Jensen, J. B., Pedersen, J. S., Beck, M., Theodorescu, D. ... Orntoft, T. F. (2014). Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties. Cancer Research, 74(20), 5758-5771. https://doi.org/10.1158/0008-5472.CAN-13-3512

Jiang, L., Edwards, S. M., Thomsen, B., Workman, C. T., Guldbrandtsen, B. & Sørensen, P. (2014). A random set scoring model for prioritization of disease candidate genes using protein complexes and data-mining of GeneRIF, OMIM and PubMed records. BMC Bioinformatics , 15(315), 1-13. https://doi.org/10.1186/1471-2105-15-315

Sørensen, K. K., Simonsen, J. B., Maolanon, N. N., Stougaard, J. & Jensen, K. J. (2014). Chemically synthesized 58-mer LysM domain binds lipochitin oligosaccharide. ChemBioChem, 15(14), 2097-105. https://doi.org/10.1002/cbic.201402125

Lund, F. W., Jensen, M. L. V., Christensen, T., Nielsen, G. K., Heegaard, C. W. & Wüstner, D. (2014). SpatTrack: An Imaging Toolbox for Analysis of Vesicle Motility and Distribution in Living Cells. Traffic, 15(12), 1406-1429. https://doi.org/10.1111/tra.12228

Kjaer-Sorensen, K., Engholm, D. H., Jepsen, M. R., Morch, M. G., Weyer, K., Hefting, L. L., Skov, L. L., Laursen, L. S. & Oxvig, C. (2014). Pregnancy-associated plasma protein-A2 modulates development of cranial cartilage and angiogenesis in zebrafish embryos. Journal of Cell Science. https://doi.org/10.1242/jcs.152587

Tesauro, C., Graziani, G., Arnò, B., Zuccaro, L., Muzi, A., D Annessa, I., Santori, E., Tentori, L., Leonetti, C., Fiorani, P. & Desideri, A. (2014). Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers. Journal of Experimental and Clinical Cancer Research (Online), 33(71), 1-8. https://doi.org/10.1186/s13046-014-0071-z

Paslawski, W., Andreasen, M., Nielsen, S. B., Lorenzen, N., Thomsen, K., Kaspersen, J. D., Pedersen, J. S. & Otzen, D. (2014). High stability and cooperative unfolding of cytotoxic α-synuclein oligomers. Biochemistry, 53(39), 6252-6263. https://doi.org/10.1021/bi5007833

Gingold, H., Tehler, D., Christoffersen, N. R., Nielsen, M. M., Asmar, F., Kooistra, S. M., Christophersen, N. S., Christensen, L. L., Borre, M., Sørensen, K. D., Andersen, L. D., Andersen, C. L., Hulleman, E., Wurdinger, T., Ralfkiær, E., Helin, K., Grønbæk, K., Orntoft, T., Waszak, S. M. ... Pilpel, Y. (2014). A dual program for translation regulation in cellular proliferation and differentiation. Cell, 158(6), 1281-92. https://doi.org/10.1016/j.cell.2014.08.011

Kjær, K. H., Pahus, J., Hansen, M. F., Poulsen, J. B., Christensen, E. I., Justesen, J. & Martensen, P. M. (2014). Mitochondrial localization of the OAS1 p46 isoform associated with a common single nucleotide polymorphism. BMC Cell Biology, 15(33), 1-14. https://doi.org/10.1186/1471-2121-15-33

Song, J., Li, Q., Wang, X., Li, J., Zhang, S., Kjems, J., Besenbacher, F. & Dong, M. (2014). Evidence of Stranski-Krastanov growth at the initial stage of atmospheric water condensation. Nature Communications, 5, 1-8. Article 4837. https://doi.org/10.1038/ncomms5837

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