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Latest peer-reviewed publications at MBG

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Displaying results 1651 to 95 out of 95

Peer-reviewed publications at MBG - all years

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Martín-Encinas, E., Rubiales, G., Knudssen, B. R., Palacios, F. & Alonso, C. (2019). Straightforward synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents of hybrid Chromeno[4,3-b][1,5]Naphthyridines and Chromeno[4,3-b][1,5]Naphthyridin-6-ones. European Journal of Medicinal Chemistry, 178, 752-766. https://doi.org/10.1016/j.ejmech.2019.06.032

O'Brien, T. R., Hartmann, R. & Prokunina-Olsson, L. (2019). What makes the hepatitis C virus evolve? eLife, 8, Article e50148. https://doi.org/10.7554/eLife.50148

Alam, P., Bousset, L., Melki, R. & Otzen, D. E. (2019). α-synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities. Journal of Neurochemistry, 150(5), 522-534. https://doi.org/10.1111/jnc.14808

Karlsson, E., Andersson, E., Jones, N. C., Hoffmann, S. V., Jemth, P. & Kjærgaard, M. (2019). Coupled Binding and Helix Formation Monitored by Synchrotron-Radiation Circular Dichroism. Biophysical Journal, 117(4), 729-742. https://doi.org/10.1016/j.bpj.2019.07.014

Dupont, M. A., Humbert, C., Huber, C., Siour, Q., Guerrera, I. C., Jung, V., Christensen, A., Pouliet, A., Garfa-Traore, M., Nitschké, P., Injeyan, M., Millar, K., Chitayat, D., Shannon, P., Girisha, K. M., Shukla, A., Mechler, C., Lorentzen, E., Benmerah, A. ... Delous, M. (2019). Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion. Human Molecular Genetics, 28(16), 2720-2737. https://doi.org/10.1093/hmg/ddz091

Yang, A., Bofill-De Ros, X., Shao, T. J., Jiang, M., Li, K., Villanueva, P., Dai, L. & Gu, S. (2019). 3′ Uridylation Confers miRNAs with Non-canonical Target Repertoires. Molecular Cell, 75(3), 511-522.e4. https://doi.org/10.1016/j.molcel.2019.05.014

ElMaghraby, M. F., Andersen, P. R., Pühringer, F., Hohmann, U., Meixner, K., Lendl, T., Tirian, L. & Brennecke, J. (2019). A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production. Cell, 178(4), 964-979.e20. https://doi.org/10.1016/j.cell.2019.07.007

Song, P., Yang, C., Thomsen, J. S., Dagnaes-Hansen, F., Jakobsen, M., Bruel, A., Deleuran, B. & Kjems, J. (2019). Lipidoid-siRNA Nanoparticle-Mediated IL-1 beta Gene Silencing for Systemic Arthritis Therapy in a Mouse Model. Molecular Therapy, 27(8), 1424-1435. https://doi.org/10.1016/j.ymthe.2019.05.002

Bavafaye Haghighi, E., Knudsen, M., Laursen, B. E. & Besenbacher, S. (2019). Hierarchical classification of cancers of unknown primary using multi-omics data. Cancer Informatics, 18. https://doi.org/10.1177/1176935119872163

Samudyata, Amaral, P. P., Engström, P. G., Robson, S. C., Nielsen, M. L., Kouzarides, T. & Castelo-Branco, G. (2019). Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells. Experimental Cell Research, 381(1), 129-138. https://doi.org/10.1016/j.yexcr.2019.05.006

Jiang, M., Liu, Y., Li, R., Zheng, Y., Fu, H., Tan, Y., Moller, I. M., Fan, L., Shu, Q. & Huang, J. (2019). A Suppressor Mutation Partially Reverts the xantha Trait via Lowered Methylation in the Promoter of Genomes Uncoupled 4 in Rice. Frontiers in Plant Science, 10, Article 1003. https://doi.org/10.3389/fpls.2019.01003

Nadzieja, M., Stougaard, J. & Reid, D. (2019). A Toolkit for High Resolution Imaging of Cell Division and Phytohormone Signaling in Legume Roots and Root Nodules. Frontiers in Plant Science, 10, Article 1000. https://doi.org/10.3389/fpls.2019.01000

Anorexia Nervosa Genetics Initiative (2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics, 51(8), 1207-1214. https://doi.org/10.1038/s41588-019-0439-2

Hebelstrup, K. H. & Møller, I. M. (2019). Oxygen: Friend and foe! Biochemist, 41(4), 18-21. https://doi.org/10.1042/bio04104018

Tataru, P. & Bataillon, T. (2019). polyDFEv2.0: testing for invariance of the distribution of fitness effects within and across species. Bioinformatics (Oxford, England), 35(16), 2868-2869. https://doi.org/10.1093/bioinformatics/bty1060

Pedersen, D. V., Gadeberg, T. A. F., Thomas, C., Joram, N., Jensen, R. K., Mazarakis, S. M. M., Revel, M., El Sissy, C., Petersen, S. V., Lindorff-Larsen, K., Thiel, S., Laursen, N. S., Fremeaux-Bacchi, V. & Andersen, G. R. (2019). Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Frontiers in Immunology, 10, Article 2007. https://doi.org/10.3389/fimmu.2019.02007

Poulsen, E. T., Nielsen, N. S., Scavenius, C., Mogensen, E. H., Risør, M. W., Runager, K., Lukassen, M. V., Rasmussen, C. B., Christiansen, G., Richner, M., Vorum, H. & Enghild, J. J. (2019). The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation. Journal of Biological Chemistry, 294(31), 11817-11828. https://doi.org/10.1074/jbc.RA119.009050

Gerring, Z. F., Gamazon, E. R., Derks, E. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression. PLoS Genetics, 15(7), e1008245. Article e1008245. https://doi.org/10.1371/journal.pgen.1008245

Griffiths, A. G., Moraga, R., Tausen, M., Gupta, V., Bilton, T. P., Campbell, M. A., Ashby, R., Nagy, I., Khan, A., Larking, A., Anderson, C., Franzmayr, B., Hancock, K., Scott, A., Ellison, N. W., Cox, M. P., Asp, T., Mailund, T., Schierup, M. H. & Andersen, S. U. (2019). Breaking Free: The Genomics of Allopolyploidy-Facilitated Niche Expansion in White Clover. The Plant Cell, 31(7), 1466-1487. https://doi.org/10.1105/tpc.18.00606

Mikkelsen, K., Lykke Harwood, S., Compte, M., Merino, N., Molgaard, K., Lykkemark, S., Alvarez-Mendez, A., Blanco, F. J. & Alvarez-Vallina, L. (2019). Carcinoembryonic Antigen (CEA)-Specific 4-1BB-Costimulation Induced by CEA-Targeted 4-1BB-Agonistic Trimerbodies. Frontiers in Immunology, 10, 1791. Article 1791. https://doi.org/10.3389/fimmu.2019.01791

Calabrese, E. J., Dhawan, G., Mattson, M. P. & Rattan, S. (2019). Curcumin and hormesis with particular emphasis on neural cells. Food and Chemical Toxicology, 129, 399-404. https://doi.org/10.1016/j.fct.2019.04.053

Nielsen, T. B., Thomsen, R. P., Mortensen, M. R., Kjems, J., Nielsen, P. F., Nielsen, T. E., Kodal, A. L. B., Cló, E. & Gothelf, K. V. (2019). Peptide-Directed DNA-Templated Protein Labelling for The Assembly of a Pseudo-IgM. Angewandte Chemie International Edition, 58(27), 9068-9072. https://doi.org/10.1002/anie.201903134

GERAD1 Consortium: (2019). Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 51(7), 1193-1193. https://doi.org/10.1038/s41588-019-0450-7

Taylor, R., Long, J., Yoon, J. W., Childs, R., Sylvestersen, K. B., Nielsen, M. L., Leong, K. F., Iannaccone, S., Walterhouse, D. O., Robbins, D. J. & Iannaccone, P. (2019). Regulation of GLI1 by cis DNA elements and epigenetic marks. DNA Repair, 79, 10-21. https://doi.org/10.1016/j.dnarep.2019.04.011

Timcenko, M., Lyons, J. A., Januliene, D., Ulstrup, J. J., Dieudonné, T., Montigny, C., Ash, M. R., Karlsen, J. L., Boesen, T., Kühlbrandt, W., Lenoir, G., Moeller, A. & Nissen, P. (2019). Structure and autoregulation of a P4-ATPase lipid flippase. Nature, 571(7765), 366-370. https://doi.org/10.1038/s41586-019-1344-7

Jamal, A., Sato, Y., Shahi, S., Shamsi, W., Kondo, H. & Suzuki, N. (2019). Novel Victorivirus from a Pakistani Isolate of Alternaria alternata Lacking a Typical Translational Stop/Restart Sequence Signature. Viruses, 11(6). https://doi.org/10.3390/v11060577

Grelet, C., Froidmont, E., Hostens, M., Foldager, L., Salavati, M., Vanlierde, A., Sørensen, M. T., Ingvartsen, K. L., Crowe, M., Ferris, C. P., GplusE Consortium & Dehareng, F. (2019). A first approach to predict nitrogen efficiency of individual dairy cows through milk MIR spectra. Poster session presented at ICAR 2019, Prag, Czech Republic.

Richner, M., Pallesen, L. T., Ulrichsen, M., Poulsen, E. T., Holm, T. H., Login, H., Castonguay, A., Lorenzo, L.-E., Gonçalves, N. P., Andersen, O. M., Lykke-Hartmann, K., Enghild, J. J., Rønn, L. C. B., Malik, I. J., De Koninck, Y., Bjerrum, O. J., Vægter, C. B. & Nykjær, A. (2019). Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain. Science Advances, 5(6), Article eaav9946. https://doi.org/10.1126/sciadv.aav9946

Vang Nielsen, S., Turnbull, K. J., Roghanian, M., Bærentsen, R., Semanjski, M., Brodersen, D. E., Macek, B. & Gerdes, K. (2019). Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase. mBio, 10(3), Article e01138-19. https://doi.org/10.1128/mBio.01138-19

Drews, B., Rudolf Vegas, A., van der Weijden, V. A., Milojevic, V., Hankele, A. K., Schuler, G. & Ulbrich, S. E. (2019). Do ovarian steroid hormones control the resumption of embryonic growth following the period of diapause in roe deer (Capreolus capreolus)? Reproductive Biology, 19(2), 149-157. https://doi.org/10.1016/j.repbio.2019.04.003

Bechsgaard, J., Schou, M. F., Vanthournout, B., Hendrickx, F., Knudsen, B., Settepani, V., Schierup, M. H. & Bilde, T. (2019). Evidence for Faster X Chromosome Evolution in Spiders. Molecular Biology and Evolution, 36(6), 1281-1293. https://doi.org/10.1093/molbev/msz074

Stronen, A. V., Pertoldi, C., Iacolina, L., Kadarmideen, H. N. & Kristensen, T. N. (2019). Genomic analyses suggest adaptive differentiation of northern European native cattle breeds. Evolutionary Applications, 12(6), 1096-1113. https://doi.org/10.1111/eva.12783

Trebeschi, S., Drago, S. G., Birkbak, N. J., Kurilova, I., Cǎlin, A. M., Delli Pizzi, A., Lalezari, F., Lambregts, D. M. J., Rohaan, M. W., Parmar, C., Rozeman, E. A., Hartemink, K. J., Swanton, C., Haanen, J. B. A. G., Blank, C. U., Smit, E. F., Beets-Tan, R. G. H. & Aerts, H. J. W. L. (2019). Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers. Annals of Oncology, 30(6), 998-1004. Article mdz108. https://doi.org/10.1093/annonc/mdz108

Flygaard, R. K., Malacrida, B., Kiely, P. & Jenner, L. B. (2019). Purification and characterization of native human elongation factor 2. Protein Expression and Purification, 158, 15-19. https://doi.org/10.1016/j.pep.2019.02.005

Raniolo, S., Croce, S., Thomsen, R. P., Okholm, A. H., Unida, V., Iacovelli, F., Manetto, A., Kjems, J., Desideri, A. & Biocca, S. (2019). Cellular uptake of covalent and non-covalent DNA nanostructures with different sizes and geometries. Nanoscale, 11(22), 10808-10818. https://doi.org/10.1039/c9nr02006c

Ferrando, B., Furlanetto, A. L. D. M., Gredilla, R., Havelund, J. F., Hebelstrup, K. H., Møller, I. M. & Stevnsner, T. (2019). DNA repair in plant mitochondria - a complete base excision repair pathway in potato tuber mitochondria. Physiologia Plantarum, 166(2), 494-512. https://doi.org/10.1111/ppl.12801

Demontis, D., Rajagopal, V. M., Thorgeirsson, T. E., Als, T. D., Grove, J., Leppälä, K., Gudbjartsson, D. F., Pallesen, J., Hjorthøj, C., Reginsson, G. W., Tyrfingsson, T., Runarsdottir, V., Qvist, P., Christensen, J. H., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Huckins, L. M., Stahl, E. A., Timmermann, A. ... Børglum, A. D. (2019). Genome-wide association study implicates CHRNA2 in cannabis use disorder. Nature Neuroscience, 22, 1066-1074. https://doi.org/10.1038/s41593-019-0416-1

Zhang, Y., Gal, N., Itel, F., Westensee, I. N., Brodszkij, E., Mayer, D., Stenger, S., Castellote-Borrell, M., Boesen, T., Tabaei, S. R., Hook, F. & Stadler, B. (2019). Hybrid vesicles as intracellular reactive oxygen species and nitric oxide generators. Nanoscale, 11(24), 11530-11541. https://doi.org/10.1039/c9nr02584g

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O'Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C. ... Binder, E. B. (2019). Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. Nature Communications, 10, Article 2548. https://doi.org/10.1038/s41467-019-10461-0

Furlanetto, A. L. D. M., Cadena, S. M. S. C., Martinez, G. R., Ferrando, B., Stevnsner, T. & Møller, I. M. (2019). Short-term high temperature treatment reduces viability and inhibits respiration and DNA repair enzymes in Araucaria angustifolia cells. Physiologia Plantarum, 166(2), 513-524. https://doi.org/10.1111/ppl.12793

Lautrup, S., Caponio, D., Cheung, H. H., Piccoli, C., Stevnsner, T., Chan, W. Y. & Fang, E. F. (2019). Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases. Biogerontology, 20(3), 255-269. https://doi.org/10.1007/s10522-019-09798-2

Fedosov, S. N., Nexo, E. & Heegaard, C. W. (2019). Vitamin B ₁₂ and its binding proteins in milk from cow and buffalo in relation to bioavailability of B ₁₂. Journal of Dairy Science, 102(6), 4891-4905. https://doi.org/10.3168/jds.2018-15016

Kongsted, H., Foldager, L. & Sørensen, J. T. (2019). Tail bites in free-range based finisher pig systems: prevalence and risk factors. Abstract from 11th symposium of porcine health management, Utrecht, Netherlands.

Škugor , M., Valero Moreno, J., Murayama , K., Centola, M., Asanuma, H. & Famulok, M. (2019). Orthogonally Photocontrolled Non‐Autonomous DNA Walker. Angewandte Chemie International Edition, 58(21), 6948-6951. https://doi.org/10.1002/anie.201901272

Stougaard, M., Jakobsen, A.-K., Johnsen, L. Ø., Thomsen, R., Holm, K., Franch, O., Knudsen, B. R., Riber-Hansen, R., Steiniche, T. & Ulhøi, B. P. (2019). Comparison of FISH and NGS Based 1p/19q Co-Deletion in Gliomas.

Bofill-De Ros, X., Chen, K., Chen, S., Tesic, N., Randjelovic, D., Skundric, N., Nesic, S., Varjacic, V., Williams, E. H., Malhotra, R., Jiang, M. & Gu, S. (2019). QuagmiR: A cloud-based application for isomiR big data analytics. Bioinformatics, 35(9), 1576-1578. https://doi.org/10.1093/bioinformatics/bty843

Acosta-Jurado, S., Rodríguez-Navarro, D. N., Kawaharada, Y., Rodríguez-Carvajal, M. A., Gil-Serrano, A., Soria-Díaz, M. E., Pérez-Montaño, F., Fernández-Perea, J., Niu, Y., Alias-Villegas, C., Jiménez-Guerrero, I., Navarro-Gómez, P., López-Baena, F. J., Kelly, S., Sandal, N., Stougaard, J., Ruiz-Sainz, J. E. & Vinardell, J. M. (2019). Sinorhizobium fredii HH103 nolR and nodD2 mutants gain capacity for infection thread invasion of Lotus japonicus Gifu and Lotus burttii. Environmental Microbiology, 21(5), 1718-1739. https://doi.org/10.1111/1462-2920.14584

Hendriks, I. A., Larsen, S. C. & Nielsen, M. L. (2019). An advanced strategy for comprehensive profiling of ADP-ribosylation sites using mass spectrometry-based proteomics. Molecular and Cellular Proteomics, 18(5), 1010-1024. https://doi.org/10.1074/mcp.TIR119.001315

Wachter, S., Jung, J., Shafiq, S., Basquin, J., Fort, C., Bastin, P. & Lorentzen, E. (2019). Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly. EMBO Journal, 38(9), Article e101251. https://doi.org/10.15252/embj.2018101251

Polimanti, R., Peterson, R. E., Ong, J.-S., MacGregor, S., Edwards, A. C., Clarke, T.-K., Frank, J., Gerring, Z., Gillespie, N. A., Lind, P. A., Maes, H. H., Martin, N. G., Mbarek, H., Medland, S. E., Streit, F., Agrawal, A., Edenberg, H. J., Kendler, K. S., Lewis, C. M. ... Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium. Psychological Medicine, 49(7), 1218-1226. https://doi.org/10.1017/S0033291719000667

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Revised 17.02.2026

Lisbeth Heilesen

Department of Molecular Biology and Genetics

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