Kogelman, L. J. A., Zhernakova, D. V., Westra, H. J., Cirera, S., Fredholm, M., Franke, L.
& Kadarmideen, H. N. (2015).
An integrative systems genetics approach reveals potential causal genes and pathways related to obesity.
Genome Medicine,
7(1), 1-15. Article 105.
https://doi.org/10.1186/s13073-015-0229-0
Zeng, G., Vad, B. S., Dueholm, M. S., Christiansen, G., Nilsson, M., Tolker-Nielsen, T., Nielsen, P. H.
, Meyer, R. L. & Otzen, D. E. (2015).
Functional bacterial amyloid increases Pseudomonas biofilm hydrophobicity and stiffness.
Frontiers in Microbiology,
6, 1099.
https://doi.org/10.3389/fmicb.2015.01099
Hede, M. S., Nkem Okorie, P., Kirk Fruekilde, S.
, Fjelstrup, S., Thomsen, J., Franch, O., Tesauro, C., Tobias Bugge, M.
, Christiansen, M., Stephane, P., Lotsch, F., Ghyslain, M.-N., Mischlinger, J., Adegnika, A. A.
, Pedersen, F. S., Ho, Y.-P., Petersen, E., Stougaard, M., Ramharter, M.
& Knudsen, B. R. (2015).
Refined Method for Droplet Microfluidics-Enabled Detection of Plasmodium falciparum Encoded Topoisomerase I in Blood from Malaria Patients.
Micromachines,
6(10), 1505-1513.
https://doi.org/10.3390/mi6101432
Perrault, I., Halbritter, J., Porath, J. D., Gerard, X., Braun, D. A., Gee, H. Y., Fathy, H. M., Saunier, S., Cormier-Daire, V., Thomas, S. R., Attie-Bitach, T., Boddaert, N.
, Taschner, M., Schueler, M.
, Lorentzen, E., Lifton, R. P., Lawson, J. A., Garfa-Traore, M., Otto, E. A. ... Hildebrandt, F. (2015).
IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype.
American Journal of Medical Genetics. Part C: Seminars in Medical Genetics,
52(10), 657-665.
Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P.-R., Bhatia, G., Do, R., Hayeck, T., Won, H.-H., Kathiresan, S., Pato, M., Pato, C., Tamimi, R., Stahl, E., Zaitlen, N., Pasaniuc, B.
... Børglum, A. (2015).
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
American Journal of Human Genetics,
97(4), 576-92.
https://doi.org/10.1016/j.ajhg.2015.09.001
Bizet, A. A., Becker-Heck, A., Ryan, R., Weber, K., Filhol, E., Krug, P., Halbritter, J., Delous, M., Lasbennes, M. C., Linghu, B., Oakeley, E. J., Zarhrate, M., Nitschke, P., Garfa-Traore, M., Serluca, F.
, Yang, F., Bouwmeester, T., Pinson, L., Cassuto, E. ... Saunier, S. (2015).
Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization.
Nature Communications,
6, 8666.
Holt, D. B., Gupta, V., Meyer, D., Abel, N. B., Andersen, S. U., Stougaard, J. & Markmann, K. (2015).
micro RNA 172 (miR172) signals epidermal infection and is expressed in cells primed for bacterial invasion in Lotus japonicus roots and nodules.
New Phytologist,
208(1), 241-256.
https://doi.org/10.1111/nph.13445
Jiang, Z., Zhang, S., Yang, C., Zadegan, R. M., Kjems, J., Huang, Y.
, Besenbacher, F. & Dong, M. (2015).
Serum-induced degradation of 3D DNA box origami observed with high-speed atomic force microscopy (vol 8, pg 2170, 2015).
Nano Research,
8(10), 3446-3446.
https://doi.org/10.1007/s12274-015-0848-1
Patron, N. J., Orzaez, D., Marillonnet, S., Warzecha, H.
, Matthewman, C., Youles, M., Raitskin, O., Leveau, A., Farré, G., Rogers, C., Smith, A., Hibberd, J., Webb, A. A. R., Locke, J., Schornack, S., Ajioka, J., Baulcombe, D. C., Zipfel, C., Kamoun, S. ... Haseloff, J. (2015).
Standards for plant synthetic biology: a common syntax for exchange of DNA parts.
New Phytologist,
208(1), 13-9.
https://doi.org/10.1111/nph.13532
Sun, M., Yang, C., Zheng, J., Wang, M.
, Chen, M., Le, D. Q. S., Kjems, J. & Bünger, C. (2015).
Enhanced efficacy of chemotherapy for breast cancer stem cells by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense.
Acta Biomaterialia,
28, 171–182.
https://doi.org/10.1016/j.actbio.2015.09.029
Lauber, C., Vieyres, G.
, Terczynska-Dyla, E., Kusuma, A., Dijkman, R.
, Gad, H. H., Akhtar, H., Geffers, R., Vondran, F., Thiel, V., Kaderali, L., Pietschmann, T.
& Hartmann, R. (2015).
Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells. Genes and Immunity,
16, 414-421.
https://doi.org/10.1038/gene.2015.23
Pant, S. D., Karlskov-Mortensen, P., Jacobsen, M. J., Cirera, S., Kogelman, L. J. A., Bruun, C. S., Mark, T., Jørgensen, C. B., Grarup, N., Appel, E. V. R., Galjatovic, E. A. A., Hansen, T., Pedersen, O., Guerin, M., Huby, T., Lesnik, P., Meuwissen, T. H. E.
, Kadarmideen, H. N. & Fredholm, M. (2015).
Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans.
PLoS One,
10(9), Article e0137356.
https://doi.org/10.1371/journal.pone.0137356
Kløverpris, S., Mikkelsen, J. H., Pedersen, J. H., Jepsen, M. R., Laursen, L. S., Petersen, S. V. & Oxvig, C. (2015).
Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A.
Journal of Biological Chemistry,
290(36), 21915-21924.
https://doi.org/10.1074/jbc.M115.650143
Meier, S. M., Agerbo, E., Maier, R.
, Pedersen, C. B., Lang, M.
, Grove, J., Hollegaard, M. V., Demontis, D., Trabjerg, B. B., Hjorthøj, C., Ripke, S., Degenhardt, F., Nöthen, M. M., Rujescu, D., Maier, W., Werge, T.
, Mors, O., Hougaard, D. M., Børglum, A. D. ... MooDS SCZ Consortium (2015).
High loading of polygenic risk in cases with chronic schizophrenia.
Molecular Psychiatry, 1-6.
https://doi.org/10.1038/mp.2015.130
Buttenschøn, H. N., Foldager, L., Elfving, B., Plougmann, P. H., Uher, R.
& Mors, O. (2015).
Neurotrophic factors in depression in response to treatment. Journal of Affective Disorders,
183, 287-94.
Siupka, P., Hamming, O. T., Kang, L.
, Gad, H. H. & Hartmann, R. (2015).
A conserved sugar bridge connected to the WSXWS motif has an important role for transport of IL-21R to the plasma membrane.
Genes and Immunity,
16(6), 405-413.
https://doi.org/10.1038/gene.2015.22
Chen, M., Le, D. Q. S., Kjems, J., Bünger, C. & Lysdahl, H. (2015).
Improvement of distribution and osteogenic differentiation of human mesenchymal stem cells by hyaluronic acid and β-tricalcium phosphate-coated polymeric scaffold in vitro.
BioResearch Open Access,
4(1), 363-373.
https://doi.org/10.1089/biores.2015.0021
Steinberger, M., Föller, M., Vogelgesang, S., Krautwald, M., Landsberger, M., Winkler, C. K., Kasch, J.
, Füchtbauer, E. M., Kuhl, D., Voelkl, J., Lang, F. & Brinkmeier, H. (2015).
Lack of the serum- and glucocorticoid-inducible kinase SGK1 improves muscle force characteristics and attenuates fibrosis in dystrophic mdx mouse muscle.
Pflügers Archiv - European Journal of Physiology,
1965-1974(10), 1965-1974.
https://doi.org/10.1007/s00424-014-1645-5
Seweryn, P., Van, L. B., Kjeldgaard, M., J. Russo, C., A. Passmore, L., Hove-Jensen, B.
, Jochimsen, B. & Brodersen, D. E. (2015).
Structural insights into the bacterial carbon - phosphorus lyase machinery.
Nature,
525, 68-72.
https://doi.org/10.1038/nature14683
Vanwalleghem, G., Fontaine, F., Lecordier, L., Tebabi, P., Klewe, K., Nolan, D. P., Yamaryo-Botté, Y., Botté, C., Kremer, A., Burkard, G. S., Rassow, J., Roditi, I., Pérez-Morga, D. & Pays, E. (2015).
Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1.
Nature Communications,
6, Article 8078.
https://doi.org/10.1038/ncomms9078
Koldsø, H., Andersen, O. J., Nikolajsen, C. L., Scavenius, C., Sørensen, C. S., Underhaug, J., Runager, K., Nielsen, N. C., Enghild, J. J. & Schiøtt, B. (2015).
Early Events in the Amyloid Formation of the A546T Mutant of Transforming Growth Factor Beta Induced Protein (TGFBIp) in Corneal Dystrophies Compared to the Non-Fibrillating R555W and R555Q Mutants.
Biochemistry,
54(36), 55546-5556.
https://doi.org/10.1021/acs.biochem.5b00473
Thomsen, J., Hjortebjerg, R., Espelund, U., Ørtoft, G., Vestergaard, P., Magnusson, N. E., Conover, C. A.
, Tramm, T., Hager, H., Høgdall, C., Høgdall, E.
, Oxvig, C. & Frystyk, J. (2015).
PAPP-A proteolytic activity enhances IGF bioactivity in ascites from women with ovarian carcinoma.
OncoTarget,
6(31), 32266-32278.
https://doi.org/10.18632/oncotarget.5010
Altmeyer, M., Neelsen, K. J., Teloni, F., Pozdnyakova, I., Pellegrino, S., Grøfte, M., Rask, M.-B. D., Streicher, W., Jungmichel, S.
, Nielsen, M. L. & Lukas, J. (2015).
Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).
Nature Communications,
6, 1-12. Article 8088.
https://doi.org/10.1038/ncomms9088
Bøtkjær, J. A., Jeppesen, J. V., Wissing, M. L.
, Kløverpris, S., Oxvig, C., Mason, J. I., Borgbo, T. & Andersen, C. Y. (2015).
Pregnancy-associated plasma protein A in human ovarian follicles and its association with intrafollicular hormone levels.
Fertility and Sterility,
104(5), 1294-1301.
https://doi.org/10.1016/j.fertnstert.2015.07.1152
Allen, E. H. A., Courtney, D. G., Atkinson, S. D., Moore, J. E., Mairs, L.
, Toftgaard Poulsen, E., Schiroli, D., Maurizi, E., Cole, C., Hickerson, R. P., James, J., Murgatroyd, H., Smith, F. J. D., MacEwen, C.
, Enghild, J. J., Nesbit, M. A., Leslie Pedrioli, D. M., McLean, W. H. I. & Moore, C. B. T. (2015).
Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy.
Human Molecular Genetics,
25(6), 1176-1191.
https://doi.org/10.1093/hmg/ddw001
Mayle, R., Campbell, I. M., Beck, C. R.
, Yu, Y., Wilson, M., Shaw, C. A.
, Bjergbaek, L., Lupski, J. R. & Ira, G. (2015).
DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage.
Science,
349(6249), 742-747.
https://doi.org/10.1126/science.aaa8391
Jakobsen, A.-K., Lauridsen, K. L., Samuel, E. B., Proszek, J.
, Knudsen, B. R., Hager, H. & Stougaard, M. (2015).
Correlation between topoisomerase I and tyrosyl-DNA phosphodiesterase 1 activities in non-small cell lung cancer tissue.
Experimental and Molecular Pathology,
99(1), 56-64.
https://doi.org/10.1016/j.yexmp.2015.05.006
Ma, Z.
, Dagnaes-Hansen, F., Løvschall, H., Song, W., Nielsen, G. K., Yang, C., Wang, Q.
, Kjems, J. & Gao, S. (2015).
Macrophage-mediated nanoparticle delivery to the periodontal lesions in established murine model via Pg-LPS induction.
Journal of Oral Pathology & Medicine,
44(7), 538-542.
https://doi.org/10.1111/jop.12269
Wang, Z., D'Annessa, I.
, Tesauro, C., Croce, S., Ottaviani, A., Fiorani, P. & Desideri, A. (2015).
Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation.
Biochimica et Biophysica Acta - Proteins and Proteomics,
1854(8), 860-868.
https://doi.org/10.1016/j.bbapap.2015.04.017
Dutheil, J. Y.
, Munch, K., Nam, K., Mailund, T. & Schierup, M. H. (2015).
Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low Divergence.
PLoS Genetics,
11(8), e1005451.
https://doi.org/10.1371/journal.pgen.1005451
Frahm, H., Hansen, S. K., Vad, B. S., Nielsen, E. H., Nielsen, J. T., Vosegaard, T., Skrydstrup, T. & Otzen, D. E. (2015).
The natural, peptaibolic peptide SPF-5506-A4 adopts a β-bend spiral structure, shows low hemolytic activity and targets membranes through formation of large pores.
Biochimica et Biophysica Acta - Proteins and Proteomics,
1854(8), 882-889.
https://doi.org/10.1016/j.bbapap.2015.03.003
Clement, L. L., Tsakos, M., Schaffert, E. S., Scavenius, C., Enghild, J. J. & Poulsen, T. B. (2015).
The amido-pentadienoate-functionality of the rakicidins is a thiol reactive electrophile: development of a general synthetic strategy.
Chemical Communications,
51(62), 12427-12430.
https://doi.org/10.1039/c5cc04500b
Steffensen, L. B., Mortensen, M. B., Kjolby, M., Hagensen, M. K., Oxvig, C. & Bentzon, J. F. (2015).
Disturbed Laminar Blood Flow Vastly Augments Lipoprotein Retention in the Artery Wall: A Key Mechanism Distinguishing Susceptible From Resistant Sites.
Arteriosclerosis, Thrombosis, and Vascular Biology,
35, 1928-1935.
https://doi.org/10.1161/ATVBAHA.115.305874
Kawaharada, Y., Kelly, S., Nielsen, M. W., Hjuler, C. T.
, Gysel, K., Muszyński, A., Carlson, R. W.
, Thygesen, M. B., Sandal, N., Asmussen, M. H., Vinther, M., Andersen, S. U., Krusell, L., Thirup, S., Jensen, K. J., Ronson, C. W.
, Blaise, M., Radutoiu, S. & Stougaard, J. (2015).
Receptor-mediated exopolysaccharide perception controls bacterial infection.
Nature,
523, 308-312.
https://doi.org/10.1038/nature14611
Roedgaard, M., Fredsoe, J., Pedersen, J. M., Bjergbaek, L. & Andersen, A. H. (2015).
DNA Topoisomerases Are Required for Preinitiation Complex Assembly during GAL Gene Activation.
PLoS One,
10(7), 1-15. Article e0132739.
https://doi.org/10.1371/journal.pone.0132739
Zhang, H., Wang, W.-Q., Liu, S.-J.
, Møller, I. M. & Song, S.-Q. (2015).
Proteome Analysis of Poplar Seed Vigor.
PLoS One,
10(7), Article e0132509.
https://doi.org/10.1371/journal.pone.0132509
Perrault, I., Halbritter, J., Porath, J., Gerard, X., Braun, D., Gee, H., Fathy, H., Saunier, S., Cormier-Daire, V., Thomas, S., Attié-Bitach, T., Boddaert, N., Taschner, M., Schueler, M.
, Lorentzen, E., Lifton, R., Otto, E., Bastin, P., Kaplan, J. ... Rozet, J. M. (2015).
Mutations of IFT81, encoding an IFT-B core protein, as a rare cause of a ciliopathy.
Cilia, (SUPPLEMENT 1), Article P7.
https://doi.org/10.1186/2046-2530-4-S1-P7