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Department of Molecular Biology and Genetics

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Latest peer-reviewed publications at MBG

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Displaying results 3451 to 62 out of 62

Peer-reviewed publications at MBG - all years

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Tzivelekidis, T., Jank, T., Pohl, C., Schlosser, A., Rospert, S., Knudsen, C. R., Rodnina, M., Belyi, Y. & Aktories, K. (2011). Aminoacyl-tRNA-charged eukaryotic elongation factor 1A is a bona fide substrate for Legionelle pneumophila effector glucosyltransferases. PLoS One, 6(12), e29525. https://doi.org/10.1371/journal.pone.0029525

Dienemann, C., Bøggild, A., Winther, K. S., Gerdes, K. & Brodersen, D. (2011). Crystal Structure of the VapBC Toxin–Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly. Journal of Molecular Biology, 414(5), 713-722. https://doi.org/10.1016/j.jmb.2011.10.024

Gårdsvoll, H., Kjærgaard, M., Jacobsen, B., Kriegbaum, M. C., Huang, M. & Ploug, M. (2011). Mimicry of the regulatory role of urokinase in lamellipodia formation by introduction of a non-native interdomain disulfide bond in its receptor. Journal of Biological Chemistry, 286(50), 43515-26. https://doi.org/10.1074/jbc.M111.300020

Kogelman, L. J. A., Byrne, K., Vuocolo, T., Watson-Haigh, N. S., Kadarmideen, H. N., Kijas, J. W., Oddy, H. V., Gardner, G. E., Gondro, C. & Tellam, R. L. (2011). Genetic architecture of gene expression in ovine skeletal muscle. BMC Genomics, 12, Article 607. https://doi.org/10.1186/1471-2164-12-607

Bak, M., Rasmussen, J. T. & Nielsen, N. C. (2011). SIMPSON - An important driver for numerical simulations in solid-state NMR spectroscopy. Journal of Magnetic Resonance, 213(2), 401-403. https://doi.org/10.1016/j.jmr.2011.08.002

Patro, B. S., Frøhlich, R., Bohr, V. A. & Stevnsner, T. (2011). WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes. Journal of Cell Science, 124(23), 3967-3979. https://doi.org/10.1242/jcs.081372

Abdallah, M., Grove, J., Hougaard, D. M., Nørgaard-Pedersen, B., Ibrahimov, F. & Mortensen, E. L. (2011). Autism Spectrum Disorders and Maternal Serum α-Fetoprotein Levels During Pregnancy. The Canadian Journal of Psychiatry, 56(12).

Chaudhary, S., Pak, J. E., Pedersen, B. P., Bang, L. J., Zhang, L. B., Ngaw, S. M. M., Green, R. G., Sharma, V. & Stroud, R. M. (2011). Efficient expression screening of human membrane proteins in transiently transfected Human Embryonic Kidney 293S cells. Methods, 55(4), 273-280. https://doi.org/10.1016/j.ymeth.2011.08.018

Kadarmideen, H. N., Ali, A. A., Thomson, P. C., Müller, B. & Zinsstag, J. (2011). Polymorphisms of the SLC11A1 gene and resistance to bovine tuberculosis in African Zebu cattle. Animal Genetics, 42(6), 656-658. https://doi.org/10.1111/j.1365-2052.2011.02203.x

Kjærgaard, M., Iešmantavičius, V. & Poulsen, F. M. (2011). The interplay between transient α-helix formation and side chain rotamer distributions in disordered proteins probed by methyl chemical shifts. Protein Science, 20(12), 2023-34. https://doi.org/10.1002/pro.726

Wiklund, E. D., Gao, S., Hulf, T., Sibbritt, T., Nair, S., Costea, D. E., Villadsen, S. B., Bakholdt, V., Bramsen, J. B., Sorensne, J. A., Krogdahl, A., Clark, S. J. & Kjems, J. (2011). MicroRNA Alterations and Associated Aberrant DNA Methylation Patterns across Multiple Sample Types in Oral Squamous Cell Carcinoma. PLoS One, 61(1), e27840 (1-11). http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0027840

Rao, R. S. P. & Møller, I. M. (2011). Pattern of occurrence and occupancy of carbonylation sites in proteins. Proteomics, 11(21), 4166-4173. https://doi.org/10.1002/pmic.201100223

Zhan, B., Fadista, J., Thomsen, B., Hedegaard, J., Panitz, F. & Bendixen, C. (2011). Global assessment of genomic variation in cattle by genome resequencing and high-throughput genotyping. BMC Genomics, 12(557). https://doi.org/10.1186/1471-2164-12-557

Larsen, J., Pettersson, O. J., Jakobsen, M., Thomsen, R., Pedersen, C. B., Hertz, J. M., Gregersen, N., Corydon, T. J. & Jensen, T. G. (2011). Myoblasts generated by lentiviral mediated MyoD transduction of myotonic dystrophy type 1 (DM1) fibroblasts can be used for assays of therapeutic molecules. BMC Research Notes, 4, 490. https://doi.org/10.1186/1756-0500-4-490

Nielsen, G. K., Dagnaes-Hansen, F., Holm, I. E., Meaney, S., Symula, D., Andersen, N. T. & Heegaard, C. W. (2011). Protein replacement therapy partially corrects the cholesterol-storage phenotype in a mouse model of Niemann-Pick type C2 disease. PLoS One, 6(11), e27287. https://doi.org/10.1371/journal.pone.0027287

Goodswen, S. J. & Kadarmideen, H. (2011). A Genetic Tool to Derive Haplotype Blocks and Measure Genomic Diversity in Populations Using SNP Genotypes: In Book: Bioinformatics – Trends and Methodologies, Edited by Dr. Mahmood A. Mahdavi. INTECH. https://doi.org/10.5772/22292

Du, X., Wang, L., Wang, Y., Andreasen, M., Zhan, D., Feng, Y., Li, M., Zhao, M., Otzen, D., Xue, D., Yang, Y. & Liu, R. (2011). Aβ_1-16Can Aggregate and induce the Production of Reactive Oxygen Species, Nitric Oxide, and Inflammatory Cytokines. Journal of Alzheimer's Disease, 27(2), 401-413. https://doi.org/10.3233/JAD-2011-110476

Zwieb, C., Nakao, Y., Nakashima, T., Takagi, H., Goda, S., Andersen, E. S., Kakuta, Y. & Kimura, M. (2011). Structural modeling of RNase P RNA of the hyperthermophilic archaeon Pyrococcus horikoshii OT3. Biochemical and Biophysical Research Communications, 414(3), 517-522. https://doi.org/10.1016/j.bbrc.2011.09.098

Hua, Y., Duan, S., Murmann, A. E., Larsen, N., Kjems, J., Lund, A. H. & Peter, M. E. (2011). miRConnect:Identifying effector genes of miRNAs and miRNA families in cancer cells. PLoS One, 6(10), e26521. https://doi.org/10.1371/journal.pone.0026521

Møller, I. M., Rogowska-Wrzesinska, A. & Rao, R. S. P. (2011). Protein carbonylation and metal-catalyzed protein oxidation in a cellular perspective. Journal of Proteomics, 74(11), 2228-2242. https://doi.org/10.1016/j.jprot.2011.05.004

Thorsen, K., Schepeler, T., Øster, B., Rasmussen, M. H., Vang, S., Wang, K., Hansen, K. Q., Lamy, P., Pedersen, J. S., Eller, A. Ø., Mansilla, F., Laurila, K., Wiuf, C. H., Laurberg, S., Dyrskjot, L., Orntoft, T. F. & Andersen, C. L. (2011). Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis. BMC Genomics, 12(1), 505. https://doi.org/10.1186/1471-2164-12-505

Abdallah, M., Greaves-Lord, K., Grove, J., Nørgaard-Pedersen, B., Hougaard, D. M. & Mortensen, E. L. (2011). Psychiatric Comorbidities in Autism Spectrum Disorders: Findings from a Danish Historic Birth Cohort. European Child & Adolescent Psychiatry, 20(11-12), 599-601. https://doi.org/10.1007/s00787-011-0220-2

Vassallo, O., Castelli, S., D'Annessa, I., della Rocca, B. M., Stella, L., Knudsen, B. R. & Desideri, A. (2011). Evidences of a natively unfolded state for the human topoisomerase IB N-terminal domain. Amino Acids, 41(4), 945-953. https://doi.org/10.1007/s00726-010-0794-x

Assenholt, J., Mouaikel, J., Saguez, C., Rougemaille, M., Libri, D. & Jensen, T. H. (2011). Implication of Ccr4-Not complex function in mRNA quality control in Saccharomyces cerevisiae. RNA, 17(10), 1788-1794. https://doi.org/10.1261/rna.2919911

Damgaard, C. K. & Lykke-Andersen, J. (2011). Translational coregulation of 5'TOP mRNAs by TIA-1 and TIAR. Genes & Development, 25(19), 2057-2068. http://genesdev.cshlp.org/content/25/19/2057.long

Klinck, R., Füchtbauer, E.-M., Ahnfelt-Rønne, J., Serup, P., Jensen, J. N. & Jørgensen, M. C. (2011). A BAC transgenic Hes1-EGFP reporter reveals novel expression domains in mouse embryos. Gene Expression Patterns, 11(7), 415-426.

Kitazawa, T., Sato, T., Nishiyama, K., Asai, R., Arima, Y., Uchijima, Y., Kurihara, Y. & Kurihara, H. (2011). Identification and developmental analysis of endothelin receptor type-A expressing cells in the mouse kidney. Gene Expression Patterns, 11(7), 371-7. https://doi.org/10.1016/j.gep.2011.04.001

Hansen, T. B., Wiklund, E. D., Bramsen, J. B., Villadsen, S. B., Statham, A. L., Clark, S. J. & Kjems, J. (2011). miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA. EMBO Journal, 30(21), 4414-4422. https://doi.org/10.1038/emboj.2011.359

Rasmussen, S. G. F., Devree, B. T., Zou, Y., Kruse, A. C., Chung, K. Y., Kobilka, T. S., Thian, F. S., Chae, P. S., Pardon, E., Calinski, D., Mathiesen, J. M., Shah, S. T. A., Lyons, J. A., Caffrey, M., Gellman, S. H., Steyaert, J., Skiniotis, G., Weis, W. I., Sunahara, R. K. & Kobilka, B. K. (2011). Crystal structure of the β ₂ adrenergic receptor-Gs protein complex. Nature, 477(7366), 549-557. https://doi.org/10.1038/nature10361

Boedtkjer, E., Prætorius, J., Matchkov, V. V., Stankevicius, E., Mogensen, S., Füchtbauer, A. C., Simonsen, U., Füchtbauer, E.-M. & Aalkjaer, C. (2011). Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice. Circulation, 124(17), 1819-1829. https://doi.org/10.1161/CIRCULATIONAHA.110.015974

Branca, A., Paape, T. D., Zhou, P., Briskine, R., Farmer, A. D., Mudge, J., Bharti, A. K., Woodward, J. E., May, G. D., Gentzbittel, L., Ben, C., Denny, R., Sadowsky, M. J., Ronfort, J., Bataillon, T., Young, N. D. & Tiffin, P. (2011). Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula. Proceedings of the National Academy of Sciences (PNAS), 108(42), 864-870. https://doi.org/10.1073/pnas.1104032108

Juul, S., Ho, Y.-P., Koch, J. E., Andersen, F. F., Stougaard, M., Leong, K. W. & Knudsen, B. R. (2011). Detection of Single Enzymatic Events in Rare or Single Cells Using Microfluidics. A C S Nano, 5(10), 8305–8310.

Fedosov, S. N., Ruetz, M., Gruber, K., Fedosova, N. U. & Kräutler, B. (2011). A blue corrinoid from partial degradation of vitamin B ₁₂ in aqueous bicarbonate: Spectra, structure, and interaction with proteins of B ₁₂ transport. Biochemistry, 50(37), 8090-8101. https://doi.org/10.1021/bi200724s

Stougaard, M., Jensen, S. J., Andersen, F. F. & Knudsen, B. R. (2011). Strategies for highly sensitive biomarker detection by Rolling Circle Amplification of signals from nucleic acid composed sensors. Integrative Biology.

Slotte, T., Bataillon, T., Hansen, T. T., St Onge, K., Wright, S. I. & Schierup, M. H. (2011). Genomic determinants of protein evolution and polymorphism in Arabidopsis. Genome Biology and Evolution, 3, 1210-1219. https://doi.org/10.1093/gbe/evr094

Demontis, D., Nyegaard, M., Buttenschøn, H. N., Hedemand, A., Pedersen, C. B., Grove, J., Flint, T. J., Nordentoft, M., Werge, T., Hougaard, D. M., Sørensen, K. M., Yolken, R. H., Mors, O., Børglum, A. D. & Mortensen, P. B. (2011). Association of GRIN1 and GRIN2A-D With schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 156(8), 913-922. https://doi.org/10.1002/ajmg.b.31234

Grove, J., Demontis, D., Hollegaard, M. V., Pedersen, C. B., Ørntoft, T. F., Yolken, R., Didriksen, M., Hougaard, D., Wiuf, C. H., Mors, O., Mortensen, P. B. & Børglum, A. (2011). Genome-Wide Significant Interaction by Cytomegalovirus with Respect to Risk of Schizophrenia. Poster session presented at XIX World Congress on Psychiatric Genetics, Washington DC, United States.

Otzen, D. E. (2011). Assembling good amyloid some structures at last. Structure, 19(9), 1207-1209. https://doi.org/10.1016/j.str.2011.08.005

Valen, E., Preker, P., Andersen, P. R., Zhao, X., Chen, Y., Ender, C., Dueck, A., Meister, G., Sandelin, A. G. & Jensen, T. H. (2011). Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes. Nature Structural and Molecular Biology, 18(9), 1075-82. https://doi.org/10.1038/nsmb.2091

Bataillon, T., Zhang, T. & Kassen, R. (2011). Cost of Adaptation and Fitness Effects of Beneficial Mutations in Pseudomonas fluorescens. Genetics, 189(3), 939-949. https://doi.org/10.1534/genetics.111.130468

Behrens, M. A., Bøtkjær, K. A., Goswami, S., Oliveira, C. L. P., Jensen, J. K., Schar, C. R., Declerck, P. J., Peterson, C. B., Andreasen, P. A. & Pedersen, J. S. (2011). Activation of the zymogen to urokinase-type plasminogen activator is associated with increased interdomain flexibility. Journal of Molecular Biology, 411(2), 417-29. https://doi.org/10.1016/j.jmb.2011.05.026

Lildballe, D. L., Fedosov, S., Sherliker, P., Hin, H., Clarke, R. & Nexø, E. (2011). Association of Cognitive Impairment with Combinations of Vitamin B12-Related Parameters. Clinical Chemistry (Chicago), 57(10). https://doi.org/10.1373/clinchem.2011.165944

Thomsen, R., Christensen, D. B., Rosborg, S., Linnet, T. E., Blechingberg, J. & Nielsen, A. L. (2011). Analysis of HP1α regulation in human breast cancer cells. Molecular Carcinogenesis, 50(8), 601-613. https://doi.org/10.1002/mc.20755

Füchtbauer, A. C., Lassen, L. B., Jensen, A. B., Howard, J., Quiroga, A. D. S., Warming, S., Sørensen, A. B., Pedersen, F. S. & Füchtbauer, E.-M. (2011). Septin9 is involved in septin filament formation and cellular stability. Biological Chemistry, 392(8-9), 769-777.

Oteri, F., Falconi, M., Chillemi, G., Andersen, F. F., Oliveira, C. L. P., Pedersen, J. S., Knudsen, B. R. & Desideri, A. (2011). Simulative Analysis of a Truncated Octahedral DNA Nano-Cage Family Indicates the Single-Stranded Thymidine Linkers as the Major Player for the Conformational Variability. Journal of Physical Chemistry Part C: Nanomaterials and Interfaces, 115(34), 16819-16827.

Heckmann, A. B., Sandal, N., Bek, A. S., Madsen, L. H., Jurkiewicz, A., Nielsen, M. W., Tirichine, L. & Stougaard, J. (2011). Cytokinin induction of root nodule primordia in Lotus japonicus is regulated by a mechanism operating in the root cortex. Molecular plant-microbe interactions, 24(11), 1385-1395. https://doi.org/10.1094/MPMI-05-11-0142

Yu, M., Wang, J., Mura, M., Meng, Q.-Q., Xu, W., Gersen, H., Lægsgaard, E., Stensgaard, I., Kelly, R. E. A., Kjems, J., Linderoth, T. R., Kantorovich, L. N. & Besenbacher, F. (2011). Homochiral Xanthine Quintet Networks Self-Assembled on Au(111) Surfaces. ACS Nano, 5(8), 6651-6660. https://doi.org/10.1021/nn202157m

Dalby, R. B., Elfving, B., Plougmann, P. H., Foldager, L., Rosenberg, R. & Videbech, P. (2011). Correlations between brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor (VEGF), and vascular risk factors in late-onset major depression. Poster session presented at IBRO 8th World Congress of Neuroscience, Firenze, Italy.

Sundekilde, U., Frederiksen, P., Clausen, M. R., Larsen, L. B. & Bertram, H. C. S. (2011). Relationship between the Metabolite Profile and Technological Properties of Bovine Milk from Two Dairy Breeds Elucidated by NMR-based Metabolomics. Journal of Agricultural and Food Chemistry, 59(13), 7360-7367. https://doi.org/10.1021/j202057x

Hollegaard, M. V., Grove, J., Grauholm, J., Kreiner-Moller, E., Bonnelykke, K., Nørgaard, M., Benfield, T. L., Norgaard-Pedersen, B., Mortensen, P. B., Mors, O., Sørensen, H. T., Harboe, Z. B., Børglum, A., Demontis, D., Ørntoft, T. F., Bisgaard, H. & Hougaard, D. M. (2011). Robustness of genome-wide scanning using archived dried blood spot samples as a DNA source. BMC Genetics, 12(1), 58. https://doi.org/10.1186/1471-2156-12-58

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Lisbeth Heilesen