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Department of Molecular Biology and Genetics

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Latest peer-reviewed publications at MBG

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Displaying results 2351 to 66 out of 66

Peer-reviewed publications at MBG - all years

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Romans-Fuertes, P., Sondergaard, T. E., Sandmann, M. I. H., Wollenberg, R. D., Nielsen, K. F., Hansen, F. T., Giese, H., Brodersen, D. E. & Sørensen, J. L. (2016). Identification of the non-ribosomal peptide synthetase responsible for biosynthesis of the potential anti-cancer drug sansalvamide in Fusarium solani. Current Genetics, 62(4), 799-807. https://doi.org/10.1007/s00294-016-0584-4

Yusoff Firdaus, M., Brask, J., Munk Nielsen, P., Guo, Z. & Fedosov, S. (2016). Kinetic model of biodiesel production catalyzed by free liquid lipase from Thermomyces lanuginosus. Journal of Molecular Catalysis B: Enzymatic, 133, 55-64. https://doi.org/10.1016/j.molcatb.2016.07.011

Xu, H. H., Liu, S. J., Song, S. H., Wang, W. Q., Møller, I. M. & Song, S. Q. (2016). Proteome changes associated with dormancy release of Dongxiang wild rice seeds. Journal of Plant Physiology, 206, 68-86. https://doi.org/10.1016/j.jplph.2016.08.016

Schatz-Jakobsen, J. A., Pedersen, D. V. & Andersen, G. R. (2016). Structural insight into proteolytic activation and regulation of the complement system. Immunological Reviews, 274(1), 59-73. https://doi.org/10.1111/imr.12465

Dahl-Pedersen, K., Foldager, L., Houe, H., Herskin, M. S. & Thomsen, P. T. (2016). Do farmers, veterinarians and livestock drivers agree when assessing dairy cow lameness and fitness for transport. In Abstracts book (pp. 161)

Besenbacher, S., Sulem, P., Helgason, A., Helgason, H., Kristjansson, H., Jonasdottir, A., Jonasdottir, A., Magnusson, O. T., Thorsteinsdottir, U., Masson, G., Kong, A., Gudbjartsson, D. F. & Stefansson, K. (2016). Multi-nucleotide de novo Mutations in Humans. PLoS Genetics, 12(11), Article e1006315. https://doi.org/10.1371/journal.pgen.1006315

Teresa Muñoz-Calvo, M., Barrios, V., Pozo, J., Chowen, J. A., Martos-Moreno, G. Á., Hawkins, F., Dauber, A., Domené, H. M., Yakar, S., Rosenfeld, R. G., Pérez-Jurado, L. A., Oxvig, C., Frystyk, J. & Argente, J. (2016). Treatment with recombinant human insulin-like growth factor-1 improves growth in patients with PAPP-A2 deficiency. The Journal of Clinical Endocrinology & Metabolism, 101(11), 3879-3883. https://doi.org/10.1210/jc.2016-2751

Santana, M. H. A., Freua, M. C., Do, D. N., Ventura, R. V., Kadarmideen, H. N. & Ferraz, J. B. S. (2016). Systems genetics and genome-wide association approaches for analysis of feed intake, feed efficiency, and performance in beef cattle. Genetics and Molecular Research, 15(4), Article gmr15048930. https://doi.org/10.4238/gmr15048930

Lukassen, M. V., Scavenius, C., Thøgersen, I. B. & Enghild, J. J. (2016). The Disulfide Bond Pattern of Transforming Growth Factor Beta-Induced protein. Biochemistry, 55(39), 5610–5621. https://doi.org/10.1021/acs.biochem.6b00694

Castagnini, A., Foldager, L., Caffo, E. & Thomsen, P. H. (2016). Early-adult outcome of child and adolescent mental disorders as evidenced by a national-based case register survey. European Psychiatry, 38, 45-50. https://doi.org/10.1016/j.eurpsy.2016.04.005

Lamy, P., Nordentoft, I. K., Birkenkamp-Demtröder, K., Thomsen, M. B. H., Villesen, P., Vang, S., Hedegaard, J., Borre, M., Jensen, J. B., Ørntoft, T. F. & Andersen, L. D. (2016). Paired exome analysis reveals clonal evolution and potential therapeutic targets in urothelial carcinoma. Cancer Research, 76(19), 5894-5906. https://doi.org/10.1158/0008-5472.CAN-16-0436

Taschner, M. & Lorentzen, E. (2016). The Intraflagellar Transport Machinery. Cold Spring Harb Perspect Biol, 8(10).

Malolepszy, A., Mun, T., Sandal, N., Gupta, V., Dubin, M., Urbanski, D. F., Shah, N., Bachmann, A., Fukai, E., Hirakawa, H., Tabata, S., Nadzieja, M., Markmann, K., Su, J., Umehara, Y., Soyano, T., Miyahara, A., Sato, S., Hayashi, M. ... Andersen, S. U. (2016). The LORE1 insertion mutant resource. The Plant Journal, 88(2), 306-317. https://doi.org/10.1111/tpj.13243

Vu-Quang, H., Vinding, M. S., Nielsen, T., Ullisch, M. G., Nielsen, N. C. & Kjems, J. (2016). Theranostic Tumor Targeted Nanoparticles Combining Drug Delivery with Dual Near Infrared and (19)F Magnetic Resonance Imaging Modalities. Nanomedicine: Nanotechnology, Biology and Medicine, 12(7), 1873-1884. https://doi.org/10.1016/j.nano.2016.04.010

Pedersen, J. N., Frislev, H. K. S., Pedersen, J. S. & Otzen, D. E. (2016). Using protein-fatty acid complexes to improve vitamin D stability. Journal of Dairy Science, 99(10), 7755–7767. https://doi.org/10.3168/jds.2016-11343

Vogt, L. M., Talens, S., Scavenius, C., Enghild, J. J., Saxne, T. & Blom, A. M. (2016). Activation of complement by pigment epithelium derived protein in synovial fluid of rheumatoid arthritis patients. Immunobiology, 221(10), 1157-1157. https://doi.org/10.1016/j.imbio.2016.06.075

Shah, N., Hirakawa, H., Kusakabe, S., Sandal, N., Stougaard, J., Schierup, M. H., Sato, S. & Andersen, S. U. (2016). High-resolution genetic maps of Lotus japonicus and L. burttii based on re-sequencing of recombinant inbred lines. D N A Research, 23(5), 487-494. https://doi.org/10.1093/dnares/dsw033

Athanasiadis, G., Cheng, J. Y., Vilhjálmsson, B. J., Jørgensen, F. G., Als, T. D., Le Hellard, S., Espeseth, T., Sullivan, P. F., Hultman, C. M., Kjærgaard, P. C., Schierup, M. H. & Mailund, T. (2016). Nationwide Genomic Study in Denmark Reveals Remarkable Population Homogeneity. Genetics, 204(2), 711-722. https://doi.org/10.1534/genetics.116.189241

Christensen, L.-L., True, K. K., Hamilton, M. P., Nielsen, M. M., Djodji Damas, N., Damgaard, C. K., Ongen, H., Dermitzakis, E. T., Bramsen, J., Pedersen, J. S., Lund, A. H., Vang, S., Stribolt, K., Madsen, M. R., Laurberg, S., McGuire, S., Ørntoft, T. F. & Andersen, C. L. (2016). SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism. Molecular Oncology, 10(8), 1266-1282. https://doi.org/10.1016/j.molonc.2016.06.003

Muszyński, A., Heiss, C., Hjuler, C. T., Sullivan, J. T., Kelly, S. J., Stougaard, J., Azadi, P., Carlson, R. W. & Ronson, C. W. (2016). Structures of exopolysaccharides involved in receptor-mediated perception of Mesorhizobium loti by Lotus japonicus. Journal of Biological Chemistry, 291(40), 20946-20961. https://doi.org/10.1074/jbc.M116.743856

Trolle, C., Nielsen, M. M., Skakkebæk, A., Lamy, P., Vang, S., Hedegaard, J., Nordentoft, I., Ørntoft, T. F., Pedersen, J. S. & Gravholt, C. H. (2016). Widespread DNA hypomethylation and differential gene expression in Turner syndrome. Scientific Reports, 6, Article 34220. https://doi.org/10.1038/srep34220

Dyla, M., Andersen, J., Kjaergaard, M., Birkedal, V., Terry, D. S., Altman, R. B., Blanchard, S., Nissen, P. & Knudsen, C. R. (2016). Engineering a prototypic P-type ATPase Listeria Monocytogenes Ca(2+)-ATPase 1 for single-molecule FRET studies. Bioconjugate Chemistry, 27(9), 2176-2187. https://doi.org/10.1021/acs.bioconjchem.6b00387

Zhang, Y.-X., Xu, H.-H., Liu, S.-J., Li, N., Wang, W.-Q., Moller, I. M. & Song, S.-Q. (2016). Proteomic Analysis Reveals Different Involvement of Embryo and Endosperm Proteins during Aging of Yliangyou 2 Hybrid Rice Seeds. Frontiers in Plant Science, 7(September), Article 1394. https://doi.org/10.3389/fpls.2016.01394

Kallehauge, T. B., Kol, S., Rørdam Andersen, M., Kroun Damgaard, C., Lee, G. M. & Faustrup Kildegaard, H. (2016). Endoplasmic reticulum-directed recombinant mRNA displays subcellular localization equal to endogenous mRNA during transient expression in CHO cells. Biotechnology Journal, 11(10), 1362-1367. https://doi.org/10.1002/biot.201600347

Malinauskaite, L., Said, S., Sahin, C., Grouleff, J., Shahsavar, A., Bjerregaard, H., Noer, P. R., Severinsen, K., Boesen, T., Schiøtt, B., Sinning, S. & Nissen, P. (2016). A Conserved Leucine Occupies the Empty Substrate Site of LeuT in the Na+-free Return State. Nature Communications, 7(1), Article 11673. https://doi.org/10.1038/ncomms11673, https://doi.org/10.1038/ncomms11673

Pantusa, M., Vad, B., Lillelund, O., Kjær, L., Otzen, D. & Bartucci, R. (2016). Alpha-synuclein and familial variants affect the chain order and the thermotropic phase behavior of anionic lipid vesicles. Biochimica et Biophysica Acta - Proteins and Proteomics, 1864(9), 1206-1214. https://doi.org/10.1016/j.bbapap.2016.05.003

Gerner, L., Munack, S., Temmerman, K., Lawrence-Dörner, A. M., Besir, H., Wilmanns, M., Jensen, J. K., Thiede, B., Mills, I. G. & Morth, J. P. (2016). Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli. Data in Brief, 8, 733-740. https://doi.org/10.1016/j.dib.2016.06.033

Sztatelman, O., Łabuz, J., Hermanowicz, P., Banaś, A. K., Bazant, A., Zgłobicki, P., Aggarwal, C., Nadzieja, M., Krzeszowiec, W., Strzałka, W. & Gabryś, H. (2016). Fine tuning chloroplast movements through physical interactions between phototropins. Journal of Experimental Botany, 67(17), 4963-4978. https://doi.org/10.1093/jxb/erw265

Fukudome, M., Calvo-Begueria, L., Kado, T., Osuki, K., Rubio, M. C., Murakami, E., Nagata, M., Kucho, K., Sandal, N. N., Stougaard, J., Becana, M. & Uchiumi, T. (2016). Hemoglobin LjGlb1-1 is involved in nodulation and regulates the level of nitric oxide in the Lotus japonicus-Mesorhizobium loti symbiosis. Journal of Experimental Botany, 67(17), 5275-5283. https://doi.org/10.1093/jxb/erw290

Davidson, S., McCabe, T. M., Crotta, S., Gad, H. H., Hessel, E. M., Beinke, S., Hartmann, R. & Wack, A. (2016). IFNλ is a potent anti-influenza therapeutic without the inflammatory side effects of IFNα treatment. EMBO Molecular Medicine, 8(9), 1099-1112. https://doi.org/10.15252/emmm.201606413

Chen, Y., Pai, A. A., Herudek, J., Lubas, M., Meola, N., Järvelin, A. I., Andersson, R., Pelechano, V., Steinmetz, L. M., Jensen, T. H. & Sandelin, A. (2016). Principles for RNA metabolism and alternative transcription initiation within closely spaced promoters. Nature Genetics, 48(9), 984-994. https://doi.org/10.1038/ng.3616

Sahoo, S., Świtnicki, M. P. & Pedersen, J. S. (2016). ProbFold: a probabilistic method for integration of probing data in RNA secondary structure prediction. Bioinformatics, 32(17), 2626-2635. https://doi.org/10.1093/bioinformatics/btw175

Domanski, M., Upla, P., Rice, W. J., Molloy, K. R., Ketaren, N. E., Stokes, D. L., Jensen, T. H., Rout, M. P. & Lacava, J. (2016). Purification and analysis of endogenous human RNA exosome complexes. RNA, 22(9), 1467-1475. https://doi.org/10.1261/rna.057760.116

Hauberg, M. E., Holm-Nielsen, M. H., Mattheisen, M., Askou, A. L., Grove, J., Børglum, A. D. & Corydon, T. J. (2016). Schizophrenia risk variants affecting microRNA function and site-specific regulation of NT5C2 by miR-206. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 26(9), 1522-1526. https://doi.org/10.1016/j.euroneuro.2016.06.014

Parron, J. A., Ripolles, D., Perez, M. D., Calvo, M., Rasmussen, J. T. & Sanchez, L. (2016). Effect of heat treatment on antirotaviral activity of bovine and ovine whey. International Dairy Journal, 60(Special Issue), 78-85. https://doi.org/10.1016/j.idairyj.2016.02.030

Thomsen, M. K., Nandakumar, R., Stadler, D., Malo, A., Valls, R. M., Wang, F., Reinert, L. S., Dagnaes-Hansen, F., Hollensen, A. K., Mikkelsen, J. G., Protzer, U. & Paludan, S. R. (2016). Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection. Hepatology, 64(3), 746-759. https://doi.org/10.1002/hep.28685

Croll, T. I. & Andersen, G. R. (2016). Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4. Acta crystallographica Section D: Structural biology , 72(9), 1006-1016. https://doi.org/10.1107/S2059798316012201

Pareek, C. S., Smoczyński, R., Kadarmideen, H. N., Dziuba, P., Błaszczyk, P., Sikora, M., Walendzik, P., Grzybowski, T., Pierzchała, M., Horbańczuk, J., Szostak, A., Ogluszka, M., Zwierzchowski, L., Czarnik, U., Fraser, L., Sobiech, P., Wasowicz, K., Gelfand, B., Feng, Y. & Kumar, D. (2016). Single nucleotide polymorphism discovery in bovine pituitary gland using RNA-seq technology. PLoS One, 11(9), Article e0161370. https://doi.org/10.1371/journal.pone.0161370

Lukassen, M., Scavenius, C., Thøgersen, I. & Enghild, J. J. (2016). The disulphide bond pattern of TGFBIp. Investigative Ophthalmology & Visual Science, 57(12), Article E-abstract 4911. http://iovs.arvojournals.org/article.aspx?articleid=2563087&resultClick=1

Holm, T. H., Isaksen, T. J., Pedersen, S. G., Heuck, A., Bøttger, P., Füchtbauer, E.-M., Nedergaard, S. T., Nyengaard, J. R., Andreasen, M., Nissen, P. & Lykke-Hartmann, K. (2016). Cognitive deficits caused by a disease-mutation in the α3 Na(+)/K(+)-ATPase isoform. Scientific Reports, 6(31972), Article 31972. https://doi.org/10.1038/srep31972

Callesen, M. M., Berthelsen, M. F., Lund, S., Füchtbauer, A. C., Füchtbauer, E.-M. & Jakobsen, J. E. (2016). Recombinase-Mediated Cassette Exchange (RMCE)-in Reporter Cell Lines as an Alternative to the Flp-in System. PLoS One, 11(8), Article e0161471. https://doi.org/10.1371/journal.pone.0161471

Cervenka, I., Valnohova, J., Bernatik, O., Harnos, J., Radsetoulal, M., Sedova, K., Hanakova, K., Potesil, D., Sedlackova, M., Salasova, A., Steinhart, Z., Angers, S., Schulte, G., Hampl, A., Zdrahal, Z. & Bryja, V. (2016). Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins. Proceedings of the National Academy of Sciences of the United States of America, 113(33), 9304-9309. https://doi.org/10.1073/pnas.1608783113

Rasmussen, M. H., Lyskjær, I., Jersie-Christensen, R. R., Tarpgaard, L. S., Primdal-Bengtson, B., Nielsen, M. M., Pedersen, J. S., Hansen, T. P., Hansen, F., Olsen, J. V., Pfeiffer, P., Ørntoft, T. F. & Andersen, C. L. (2016). miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells. Nature Communications, 7, Article 12436. https://doi.org/10.1038/ncomms12436

Jensen, M. R., Bajic, G., Zhang, X., Laustsen, A. K., Koldsø, H., Skeby, K. K., Schiøtt, B., Andersen, G. R. & Vorup-Jensen, T. (2016). Structural basis for simvastatin competitive antagonism of complement receptor 3. Journal of Biological Chemistry, 291(33), 16963-16976. https://doi.org/10.1074/jbc.M116.732222

Arribas-Layton, M., Dennis, J., Bennett, E., Damgaard, C. K. & Lykke-Andersen, J. (2016). The C-terminal RGG domain of human Lsm4 promotes processing body formation stimulated by arginine dimethylation. Molecular and Cellular Biology, 36(17), 2226-2235. https://doi.org/10.1128/MCB.01102-15

Sun, C., Wakefield, D. L., Han, Y., Muller, D. A., Holowka, D. A., Baird, B. A. & Dichtel, W. R. (2016). Graphene Oxide Nanosheets Stimulate Ruffling and Shedding of Mammalian Cell Plasma Membranes. Chem, 1(2), 273-286. https://doi.org/10.1016/j.chempr.2016.06.019

Vinther, M. & Kjems, J. (2016). Interfacing DNA nanodevices with biology: Challenges, solutions and perspectives. New Journal of Physics, 18(8), Article 085005. https://doi.org/10.1088/1367-2630/18/8/085005

Jarvela, T. S., Lam, H. A., Helwig, M., Lorenzen, N., Otzen, D. E., McLean, P. J., Maidment, N. T. & Lindberg, I. (2016). The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity. Proceedings of the National Academy of Sciences (PNAS), 113(32), E4708-E4715. https://doi.org/10.1073/pnas.1601091113

Sun, M., Chen, M., Wang, M., Hansen, J., Baatrup, A., Dagnæs-Hansen, F., Rölfing, J. D., Jensen, J., Lysdahl, H., Li, H., Johannsen, M., Le, D. Q. S., Kjems, J. & Bünger, C. (2016). In vivo drug release behavior and osseointegration of a doxorubicin-loaded tissue-engineered scaffold. RSC Advances, 6(80), 76237-76245. https://doi.org/10.1039/c6ra05351c

Malmos, K. G., Bjerring, M., Jessen, C. M., Nielsen, E. H. T., Poulsen, E. T., Christiansen, G., Vosegaard, T., Skrydstrup, T., Enghild, J. J., Pedersen, J. S. & Otzen, D. E. (2016). How Glycosaminoglycans Promote Fibrillation of Salmon Calcitonin. Journal of Biological Chemistry, 291(32), 16849-16862. https://doi.org/10.1074/jbc.M116.715466

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