Kapoor, K., Finer-Moore, J. S.
, Pedersen, B. P., Caboni, L., Waight, A., Hillig, R. C., Bringmann, P., Heisler, I., Müller, T., Siebeneicher, H. & Stroud, R. M. (2016).
Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides.
Proceedings of the National Academy of Sciences (PNAS),
113(17), 4711-4716.
https://doi.org/10.1073/pnas.1603735113Dupont, D. M., Bjerregaard, N., Verpaalen, B., Andreasen, P. A. & Jensen, J. K. (2016).
Building a Molecular Trap for a Serine Protease from Aptamer and Peptide Modules.
Bioconjugate Chemistry,
27(4), 918-926.
https://doi.org/10.1021/acs.bioconjchem.6b00007
Aamann, M. D., Norregaard, R., Kristensen, M. L. V., Stevnsner, T. & Frøkiær, J. (2016).
Unilateral ureteral obstruction induces DNA repair by APE1.
American Journal of Physiology: Renal Physiology,
310(8), F763-F776.
https://doi.org/10.1152/ajprenal.00613.2014
Che, H. C., Zhang, X. Y., Wang, Y. Q., Zhang, L., Shen, X. J.
, Zhang, Y. W., Ma, Q. L., Sun, J. Y., Zhang, Y. W. & Wang, T. T. (2016).
Characterization and parameterization of aerosol cloud condensation nuclei activation under different pollution conditions.
Scientific Reports,
6, Article 24497.
https://doi.org/10.1038/srep24497
Månsson-Broberg, A., Rodin, S., Bulatovic, I., Ibarra, C., Löfling, M., Genead, R., Wärdell, E., Felldin, U., Granath, C., Alici, E., Le Blanc, K., Smith, C. I. E.
, Salašová, A., Westgren, M., Sundström, E., Uhlén, P., Arenas, E., Sylvén, C., Tryggvason, K. ... Grinnemo, K. H. (2016).
Wnt/β-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells.
Stem Cell Reports,
6(4), 607-617.
https://doi.org/10.1016/j.stemcr.2016.02.014Christiansen, J. R., Olesen, M. N., Otzen, D. E., Romero-Ramos, M. & Sanchez-Guajardo, V. (2016).
α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology.
Journal of Neuroinflammation,
13(1), Article 74.
https://doi.org/10.1186/s12974-016-0532-8
Koro, C., Hellvard, A., Delaleu, N., Binder, V.
, Scavenius, C., Bergum, B., Główczyk, I., Roberts, H. M., Chapple, I. L., Grant, M. M., Rapala-Kozik, M., Klaga, K.
, Enghild, J. J., Potempa, J. & Mydel, P. (2016).
Carbamylated LL-37 as a modulator of the immune response.
Innate Immunity,
22(3), 218-229.
https://doi.org/10.1177/1753425916631404Ferraris, P., Chandra, P. K., Panigrahi, R., Aboulnasr, F., Chava, S., Kurt, R., Pawlotsky, J.-M., Wilkens, L., Osterlund, P.
, Hartmann, R., Balart, L. A., Wu, T. & Dash, S. (2016).
Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression.
American Journal of Pathology,
186(4), 938-951.
https://doi.org/10.1016/j.ajpath.2015.11.027Louw, A. M., Kolar, M. K., Novikova, L. N., Kingham, P. J., Wiberg, M.
, Kjems, J. & Novikov, L. N. (2016).
Chitosan polyplex mediated delivery of miRNA-124 reduces activation of microglial cells in vitro and in rat models of spinal cord injury.
Nanomedicine: Nanotechnology, Biology and Medicine,
12(3), 643-653.
https://doi.org/10.1016/j.nano.2015.10.011
Taschner, M., Weber, K., Mourao, A., Vetter, M. M., Awasthi, M., Stiegler, M., Bhogaraju, S.
& Lorentzen, E. (2016).
Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex.
EMBO Journal,
35(7), 773-790.
https://doi.org/10.15252/embj.201593164
Takabatake, Y.
, Oxvig, C., Nagi, C., Adelson, K., Jaffer, S., Schmidt, H., Keely, P. J., Eliceiri, K. W., Mandeli, J. & Germain, D. (2016).
Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer.
EMBO Molecular Medicine,
8(4), 388-406.
https://doi.org/10.15252/emmm.201606273Dauber, A., Muñoz-Calvo, M. T., Barrios, V., Domené, H. M.
, Kloverpris, S., Serra-Juhé, C., Desikan, V., Pozo, J., Muzumdar, R., Martos-Moreno, G. Á., Hawkins, F., Jasper, H. G., Conover, C. A.
, Frystyk, J., Yakar, S., Hwa, V., Chowen, J. A.
, Oxvig, C., Rosenfeld, R. G. ... Argente, J. (2016).
Mutations in pregnancy-associated plasma protein A2 cause short stature due to low IGF-I availability.
EMBO Reports,
8(4), 363-374.
https://doi.org/10.15252/emmm.201506106Hjorth, C. F., Norrman, M., Wahlund, P.-O., Benie, A. J., Petersen, B. O.
, Jessen, C. M., Pedersen, T. Å., Vestergaard, K., Steensgaard, D. B.
, Pedersen, J. S., Naver, H., Hubálek, F., Poulsen, C.
& Otzen, D. (2016).
Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin.
Journal of Pharmaceutical Sciences,
105(4), 1376-1386.
https://doi.org/10.1016/j.xphs.2016.01.003
Jepsen, M. R., Kløverpris, S., Bøtkjær, J. A., Wissing, M. L., Andersen, C. Y.
& Oxvig, C. (2016).
The proteolytic activity of pregnancy-associated plasma protein-A is potentially regulated by stanniocalcin-1 and -2 during human ovarian follicle development.
Human Reproduction,
31(4), 866-874.
https://doi.org/10.1093/humrep/dew013
Stevison, L. S., Woerner, A. E., Kidd, J. M., Kelley, J. L., Veeramah, K. R., McManus, K. F., Bustamante, C. D., Hammer, M. F., Wall, J. D., Great Ape Genome Project
& Schierup, M. H. (2016).
The Time Scale of Recombination Rate Evolution in Great Apes.
Molecular Biology and Evolution,
33(4), 928-945.
https://doi.org/10.1093/molbev/msv331Reinert, T., Schøler, L. V., Thomsen, R., Tobiasen, H., Vang, S., Nordentoft, I. K., Lamy, P., Kannerup, A.-S., Mortensen, F. V., Stribolt, K., Hamilton-Dutoit, S. J., Laurberg, S., Pallisgaard, N.
, Pedersen, J. S., Ørntoft, T. F. & Andersen, C. L. (2016).
Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery.
Gut,
65(4), 625-634.
https://doi.org/10.1136/gutjnl-2014-308859
Hauberg, M. E., Roussos, P.
, Grove, J., Børglum, A. D., Mattheisen, M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium (2016).
Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants.
JAMA Psychiatry,
73(4), 369-377.
https://doi.org/10.1001/jamapsychiatry.2015.3018
Poulsen, J. B., Lescai, F., Grove, J., Bækvad-Hansen, M., Christiansen, M., Hagen, C. M., Maller, J., Stevens, C., Li, S., Li, Q., Sun, J.
, Wang, J., Nordentoft, M., Werge, T. M.
, Mortensen, P. B., Børglum, A. D., Daly, M., Hougaard, D. M., Bybjerg-Grauholm, J.
& Hollegaard, M. V. (2016).
High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA.
PLoS One,
11(4), e0153253. Article e0153253.
https://doi.org/10.1371/journal.pone.0153253
Jensen, N. F., Agama, K.
, Roy, A., Smith, D. H., Pfister, T. D., Rømer, M. U., Zhang, H.-L., Doroshow, J. H.
, Knudsen, B. R., Stenvang, J.
, Brünner, N. & Pommier, Y. (2016).
Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations.
Journal of Experimental and Clinical Cancer Research (Online),
35(1), Article 56.
https://doi.org/10.1186/s13046-016-0335-xGuerreiro, J. R., Bochenkov, V., Runager, K. S., Aslan, H., Dong, M., Enghild, J. J., De Freitas, V., Sales, M. G. F.
& Sutherland, D. (2016).
Molecular imprinting of complex matrices at localized surface plasmon resonance biosensors for screening of global interactions of polyphenols and proteins.
ACS Sensors,
1(3), 258-264.
https://doi.org/10.1021/acssensors.5b00054
de Diego, I., Ksiazek, M., Mizgalska, D., Koneru, L., Golik, P., Szmigielski, B., Nowak, M., Nowakowska, Z., Potempa, B., Houston, J. A.
, Enghild, J. J., Thøgersen, I. B., Gao, J., Kwan, A. H., Trewhella, J., Dubin, G., Gomis-Rüth, F. X., Nguyen, K.-A. & Potempa, J. (2016).
The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domain.
Scientific Reports,
6, 23123. Article 23123.
https://doi.org/10.1038/srep23123Thompson, A. W.
, Vanwalleghem, G. C., Heap, L. A. & Scott, E. K. (2016).
Functional profiles of visual-, auditory-, and water flow-responsive neurons in the Zebrafish Tectum.
Current Biology,
26(6), 743-754.
https://doi.org/10.1016/j.cub.2016.01.041Horrocks, M. H., Lee, S. F., Gandhi, S., Magdalinou, N. K., Chen, S. W., Devine, M. J., Tosatto, L.
, Kjaergaard, M., Beckwith, J. S., Zetterberg, H., Iljina, M., Cremades, N., Dobson, C. M., Wood, N. W. & Klenerman, D. (2016).
Single-molecule imaging of individual amyloid protein aggregates in human biofluids.
ACS Chemical Neuroscience,
7(3), 399–406.
https://doi.org/10.1021/acschemneuro.5b00324Alonso, C., Fuertes, M., González, M., Rubiales, G.
, Tesauro, C., Knudsen, B. R. & Palacios, F. (2016).
Synthesis and biological evaluation of indeno[1,5]naphthyridines as topoisomerase I (TopI) inhibitors with antiproliferative activity.
European Journal of Medicinal Chemistry,
115, 179-190.
https://doi.org/10.1016/j.ejmech.2016.03.031Pedersen, B. P., Gourdon, P., Liu, X., Karlsen, J. L. & Nissen, P. (2016).
Initiating heavy-atom-based phasing by multi-dimensional molecular replacement.
Acta crystallographica Section D: Structural biology ,
72(Pt 3), 440-445.
https://doi.org/10.1107/S2059798315022482
Christensen, G. J. M., Scholz, C. F. P., Enghild, J., Rohde, H.
, Kilian, M., Thürmer, A., Brzuszkiewicz, E.
, Lomholt, H. B. & Brüggemann, H. (2016).
Antagonism between Staphylococcus epidermidis and Propionibacterium acnes and its genomic basis.
BMC Genomics,
17(1), 1-14. Article 152.
https://doi.org/10.1186/s12864-016-2489-5
Scavenius, C., Nikolajsen, C. L., Stenvang, M., Thøgersen, I., Wyrozemski, L., Wisniewski, H.-G.
, Otzen, D. E., Sanggaard, K. W. & Enghild, J. J. (2016).
The compact and biologically relevant structure of inter-α-inhibitor is maintained by the chondroitin sulfate chain and divalent cations.
Journal of Biological Chemistry,
291(9), 4658-4670.
https://doi.org/10.1074/jbc.M115.678748
Bøttger, P., Pedersen, S. G., Gesslein, B., Illarionova, N.
, Isaksen, T. J., Heuck, A., Clausen, B. H.
, Füchtbauer, E.-M., Gramsbergen, J. B., Gunnarson, E., Aperia, A., Lauritzen, M., Lambertsen, K. L.
, Nissen, P. & Lykke-Hartmann, K. (2016).
Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.
Scientific Reports,
6(22047), Article 22047.
https://doi.org/10.1038/srep22047
Holm, C. K., Rahbek, S. H., Gad, H. H., Bak, R. O., Jakobsen, M. R., Jiang, Z.
, Hansen, A. L., Jensen, S. K., Sun, C., Thomsen, M. K., Laustsen, A., Nielsen, C. G., Severinsen, K., Xiong, Y., Burdette, D. L., Hornung, V., Lebbink, R. J.
, Duch, M., Fitzgerald, K. A.
... Paludan, S. R. (2016).
Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.
Nature Communications,
7, Article 10680.
https://doi.org/10.1038/ncomms10680
Madsen, J. K., Kaspersen, J. D., Andersen, K. K., Pedersen, J. S. & Otzen, D. E. (2016).
When Enzymes and Green Surfactants Meet.
Biophysical Journal,
110(3), 211A.
https://doi.org/10.1016/j.bpj.2015.11.1171
Smidt, K., Larsen, A., Brønden, A.
, Sørensen, K. S., Nielsen, J. V., Praetorius, J., Martensen, P. M. & Rungby, J. (2016).
The zinc transporter ZNT3 co-localizes with insulin in INS-1E pancreatic beta cells and influences cell survival, insulin secretion capacity, and ZNT8 expression.
BioMetals,
29(2), 287–298.
https://doi.org/10.1007/s10534-016-9915-7
Aschard, H.
, Vilhjálmsson, B. J., Joshi, A. D., Price, A. L. & Kraft, P. (2016).
Response to Day et al.
American Journal of Human Genetics,
98(2), 394-395.
https://doi.org/10.1016/j.ajhg.2015.12.020Knudsen, M., Søndergaard, D. A., Tofting-Olesen, C., Hansen, F. T., Brodersen, D. E. & Pedersen, C. S. (2016).
Computational discovery of specificity-conferring sites in non-ribosomal peptide synthetases.
Bioinformatics,
32(3), 325-329.
https://doi.org/10.1093/bioinformatics/btv600
Jordal, P. L.
, Dyrlund, T. F., Winge, K.
, Larsen, M. R., Danielsen, E. H., Wells, J. A.
, Otzen, D. E. & Enghild, J. J. (2016).
Detection of proteolytic signatures for Parkinson's disease.
Future Neurology,
11(1), 15-32.
https://doi.org/10.2217/fnl.16.3Lylloff, J. E., Hansen, L. B. S.
, Jepsen, M., Sanggaard, K. W., Vester, J. K.
, Enghild, J. J., Sørensen, S. J.
, Stougaard, P. & Glaring, M. A. (2016).
Genomic and exoproteomic analyses of cold- and alkaline-adapted bacteria reveal an abundance of secreted subtilisin-like proteases.
Microbial Biotechnology,
9(2), 245-256.
https://doi.org/10.1111/1751-7915.12343Poulsen, E. T., Nielsen, N. S., Jensen, M. M., Nielsen, E., Hjortdal, J. Ø., Kim, E. K.
& Enghild, J. J. (2016).
LASIK surgery of granular corneal dystrophy type 2 patients leads to accumulation and differential proteolytic processing of transforming growth factor beta-induced protein (TGFBIp).
Proteomics,
16(3), 539-543.
https://doi.org/10.1002/pmic.201500287
Petersen, S., Kläning, E., Andersen, B., Cameron, J.
, Sørensen, E. S. & Howard, K. (2016).
Neonatal Fc Receptor Binding Tolerance toward the Covalent Conjugation of Payloads to Cysteine 34 of Human Albumin Variants.
Molecular Pharmaceutics,
13(2), 677–682.
https://doi.org/10.1021/acs.molpharmaceut.5b00605
Reid, D. E., Heckmann, A. B., Novak, O.
, Kelly, S. & Stougaard, J. (2016).
CYTOKININ OXIDASE/DEHYDROGENASE3 maintains cytokinin homeostasis during root and nodule development in Lotus japonicus.
Plant Physiology,
170(2), 1060-1074.
https://doi.org/10.1104/pp.15.00650
Sanggaard, K. W., Dyrlund, T. F., Bechsgaard, J. S., Scavenius, C., Wang, T., Bilde, T. & Enghild, J. J. (2016).
The spider hemolymph clot proteome reveals high concentrations of hemocyanin and von Willebrand factor-like proteins.
Biochimica et Biophysica Acta - Proteins and Proteomics,
1864(2), 233-241.
https://doi.org/10.1016/j.bbapap.2015.11.004
Risor, M. W., Thomsen, L. R., Sanggaard, K. W., Nielsen, T. A., Thøgersen, I. B., Lukassen, M. V., Rossen, L., Garcia-Ferrer, I., Guevara, T.
, Scavenius, C., Meinjohanns, E., Gomis-Ruth, F. X.
& Enghild, J. J. (2016).
Enzymatic and structural characterization of the major endopeptidase in the Venus flytrap digestion fluid.
Journal of Biological Chemistry,
291(5), 2271-2287.
https://doi.org/10.1074/jbc.M115.672550
Steger, M., Tonelli, F., Ito, G., Davies, P., Trost, M., Vetter, M., Wachter, S.
, Lorentzen, E., Duddy, G., Wilson, S., Baptista, M. A. S., Fiske, B. K., Fell, M. J., Morrow, J. A., Reith, A. D., Alessi, D. R. & Mann, M. (2016).
Phosphoproteomics reveals that Parkinson’s disease kinase LRRK2 regulates a subset of Rab GTPases.
eLife,
5(JANUARY2016), Article e12813.
https://doi.org/10.7554/eLife.12813.001Bungum, H. F.
, Nygaard, U., Vestergaard, C., Martensen, P. M. & Knudsen, U. B. (2016).
Increased IL-25 levels in the peritoneal fluid of patients with endometriosis.
Journal of Reproductive Immunology,
114, 6-9.
https://doi.org/10.1016/j.jri.2016.01.003
