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Department of Molecular Biology and Genetics

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Latest peer-reviewed publications at MBG

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Displaying results 4351 to 96 out of 96

Peer-reviewed publications at MBG - all years

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Addison, W. N., Azari, F., Sørensen, E. S., Kaartinen, M. T. & McKee, M. D. (2007). Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, upregulating osteopontin and inhibiting alkaline phosphatase actvity. Journal of Biological Chemistry, 282, 15872-15883.

Nielsen, C. G., Christiansen, M. & Oxvig, C. (2007). Quantification of proteolytically active pregnancy-associated plasma protein-A using an assay based on quenched fluorescence. Clinical Chemistry, 53, 947-954.

Nielsen, C. G. & Oxvig, C. (2007). Quantitative analysis of insulin-like growth factor (IGF) modulated proteolysis of IGF binding protein-4 and -5 by pregnancy-associated plasma protein-A. Biochemistry, 46, 1982-80.

Hovgaard, M. B., Dong, M., Otzen, D. E. & Besenbacher, F. (2007). Quartz crystal microbalance studies of multilayer glucagon fibrillation at the solid-liquid interface. Biophysical Journal, 93(6), 2162-9. https://doi.org/10.1529/biophysj.107.109686

Hovgaard, M. B., Dong, M., Otzen, D. & Besenbacher, F. (2007). Quartz crystal microbalance studies of multilayer glucagons fibrillation at the solid-liquid interface. Biophysical Journal, 93(6), 2162.

Thaysen-Andersen, M., Thøgersen, I., Nielsen, HJ., Lademann, U., Brunner, N., Enghild, J. J. & Højrup, P. (2007). Rapid and individual-specific glycoprofiling of a low- abundant N-glycosylated protein tissue inhibitor of metalloproteinases-1. Mol. Cell. Proteomics.

Laursen, L. S., Kjær-Sørensen, K., Andersen, M. H. & Oxvig, C. (2007). Regulation of insulin-like growth factor (IGF) bioactivity by sequential proteolytic cleavage of IGF binding protein-4 and -5. Molecular Endocrinology, 21(5), 1246-1257.

Blechingberg, J., Lykke-Andersen, S., Jensen, T. H., Jørgensen, A. L. & Nielsen, A. L. (2007). Regulatory mechanisms for 3'-end alternative splicing and polyadenylation of the Glial Fibrillary Acidic Protein, GFAP, transcript. Nucleic Acids Research, 35(22), 7636-50. https://doi.org/10.1093/nar/gkm931

Hede, M. S., Petersen, R. L., Krüger, D., Andersen, F. F., Andersen, A. H. & Knudsen, B. R. (2007). Resolution of Holliday junction substrates by human topoisomerase I. Journal of Molecular Biology.

Andersen, E. S., Lind-Thomsen, A., Knudsen, B., Kristensen, S. E., Havgaard, J. H., Torarinsson, E., Larsen, N., Zwieb, C., Sestoft, P., Kjems, J. & Gorodkin, J. (2007). Semiautomated improvement of RNA alignments. RNA, 13, 1850-1859.

Panitz, F., Stengaard, H., Hornshøj, H., Gorodkin, J., Hedegaard, J., Cirera, S., Thomsen, B., Madsen, L. B., Høj, A., Vingborg, R., Bujie, Z., Wang, X., Wang, X. F., Wernersson, R., Jørgensen, C. B., Scheibye-Knudsen, K., Arvin, T., Lumholdt, S., Sawera, M. ... Bendixen, C. (2007). SNP mining porcine ESTs with MAVIANT, a novel tool for SNP evaluation and annotation. Bioinformatics, 23(13), i387-i391. https://doi.org/10.1093/bioinformatics/btm192

Søe, R., Mosley, R. T., Justice, M., Nielsen-Kahn, J., Shastry, M., Merrill, A. R. & Andersen, G. R. (2007). Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2. Journal of Biological Chemistry, 282, 657-666.

Washietl, S., Pedersen, J. S., Korbel, J. O., Stocsits, C., Gruber, A. R., Hackermüller, J., Hertel, J., Lindemeyer, M., Reiche, K., Tanzer, A., Ucla, C., Wyss, C., Antonarakis, S. E., Denoeud, F., Lagarde, J., Drenkow, J., Kapranov, P., Gingeras, T. R., Guigó, R. ... Stadler, P. F. (2007). Structured RNAs in the ENCODE selected regions of the human genome. Genome Research, 17(6), 852-64. https://doi.org/10.1101/gr.5650707

Berge, U., Behrens, J. & Rattan, S. (2007). Sugar-induced premature aging and altered differentiation in human epidermal keratinocytes. New York Academy of Sciences. Annals, 1100, 524-529.

Fedosov, S., Berglund, L. E., Nexø, E. & Petersen, T. E. (2007). Tetrazole derivatives and matrices as novel cobalamin coordinating compounds. J. Organometallic Chem., 692, 1234-1242.

Jonstrup, A. T., Andersen, K. R., Van, L. B. & Brodersen, D. E. (2007). The 1.4-Å crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzyme. Nucleic Acids Research, 35(9), 3153-3164. https://doi.org/10.1093/nar/gkm178

Andersen, S. U., Algreen-Petersen, R. G., Hödl, M., Jurkiewicz, A., Cvitanich, C., Braunschweig, U., Schauser, L., Oh, S.-A., Twell, D. & Jensen, E. Ø. (2007). The conserved cysteine-rich domain of a tesmin/TSO1-like protein binds zinc in vitro and TSO1 is required for both male and female fertility in Arabidopsis thaliana. Journal of Experimental Botany, 58, 3657-3670. https://doi.org/10.1093/jxb/erm215

Lykke-Andersen, S., Piñol-Roma, S. & Kjems, J. (2007). The human ADAR1 transcripts contain an alternative retained intron within a region that functions both as a 5'UTR and an ORF. RNA, 89(10).

Liu, X., Howard, K. A., Dong, M., Andersen, M. Ø., Rahbek, U. L., Johnsen, M. G., Hansen, O. C., Besenbacher, F. & Kjems, J. (2007). The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing. Biomaterials, 28(6), 1280-8. https://doi.org/10.1016/j.biomaterials.2006.11.004

Valnickova, Z., Thøgersen, I., Potempa, J. & Enghild, J. J. (2007). The intrinsic enzymatic activity of procarboxypeptidase U (TAFI) does not significantly influence the fibrinolytic rate: reply to a rebuttal. J Thromb Haemost. 2007.

Morgensen, JE., Ferreras, M., Wimmer, R., Petersen, S. V., Enghild, J. J. & Otzen, D. (2007). The Major Allergen from Birch Tree Pollen, Bet v 1, Binds and Permeabilizes Membranes. Biochemistry.

Rattan, S. (2007). The science of healthy aging: genes, milieu, and chance. New York Academy of Sciences. Annals, 1114, 1-10.

Olesen, C., Picard, M., Winther, A.-M. L., Nielsen, C. G., Morth, J. P., Oxvig, C., Møller, J. V. & Nissen, P. (2007). The structural basis of calcium transport by the calcium pump. Nature, 450(7172), 1036-1042. https://doi.org/10.1038/nature06418

Petersen, S. V., Valnickova, Z., Oury, T. D., Crapo, J. D., Nielsen, N. C. & Enghild, J. J. (2007). The Subunit Composition of Human Extracellylar Superoxide Dismutate (EC-SOD) Regulate Enzymatic Activity. BMC Biochemistry, 8, 19.

Kuhn, R. M., Karolchik, D., Zweig, A. S., Trumbower, H., Thomas, D. J., Thakkapallayil, A., Sugnet, C. W., Stanke, M., Smith, K. E., Siepel, A., Rosenbloom, K. R., Rhead, B., Raney, B. J., Pohl, A., Pedersen, J. S., Hsu, F., Hinrichs, A. S., Harte, R. A., Diekhans, M. ... Pedersen, J. S. (2007). The UCSC genome browser database: update 2007. Nucleic Acids Research, 35(Database issue), D668-73. https://doi.org/10.1093/nar/gkl928

Valnickova, Z., Thøgersen, I., Potempa, J. & Enghild, J. J. (2007). Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase. Journal of Biological Chemistry, 282(2), 1072-9.

Barciszewska, M., Barciszewska, A. M. & Rattan, S. (2007). TLC-based detection of methylated cytosine: application to aging epigenetics. Biogerontology, 8(6), 673-678.

Novotny, G. W., Sonne, S., Nielsen, J. E., Jonstrup, S. P., Hansen, M. A., Skakkebaek, N. E., Rajpert-De Meyts, E., Kjems, J. & Leffers, H. (2007). Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster. Cell Death and Differentiation, 14(4), 879-882. https://doi.org/10.1038/sj.cdd.4402090

Leppälä, J., Bechsgaard, J. S., Schierup, M. H. & Savolainen, O. (2007). Transmission ratio distortion in Arabidopsis lyrata: effects of population divergence and the S-locus. Heredity, 100(1), 71-8. https://doi.org/10.1038/sj.hdy.6801066

Frøhlich, R. F., Veigaard, C., Andersen, F. F., McClendon, A. K., Gentry, A. K., Andersen, A. H., Osherroff, N., Stevnsner, T. V. & Knudsen, B. R. (2007). Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal. Nucleic Acid Res., 35, 6170-6180.

Nielsen, M. M., Andersen, K. K., Westh, P. & Otzen, D. (2007). Unfolding of ß-sheet proteins in SDS. Biophysical Journal, (92), 3674-3685.

Dong, M., Howard, K. A., Oupicky, D., Bisht, H. J., Kjems, J. & Besenbacher, F. (2007). Visualisation of Thermal Activated Nanocarriers Using In Situ Atomic Force Microscopy. Nanotechnology.

Dong, M. D., Howard, K. A., Oupicky, D., Bisht, H., Kjems, J. & Besenbacher, F. (2007). Visualization of thermally activated nanocarriers using in situ atomic force microscopy: Nanotechnology. Nanotechnology, 18(18), Article 185501. https://doi.org/10.1088/0957-4484/18/18/185501

Wuerges, J., Geremia, S., Fedosov, S. & Randaccio, L. (2007). Vitamin B₁₂ transport proteins: Crystallographic analysis of β-axial ligand substitutions in cobalamin bound to transcobalamin. IUBMB Life, 59(11), 722-729.

Otzen, D. & Nielsen, P. H. (2007). We find them here, we find them there: Functional bacterial amyloid. Cellular and Molecular Life Sciences, 65, 910-927.

Jørgensen, F. G., Schierup, M. H. & Clark, A. G. (2006). Heterogeneity in Regional GC Content and Differential Usage of Codons and Amino Acids in GC-Poor and GC-Rich Regions of the Genome of Apis mellifera. Molecular Biology and Evolution. https://doi.org/10.1093/molbev/msl190

Munch, K. & Krogh, A. (2006). Automatic generation of gene finders for eukaryotic species. BMC Bioinformatics, 7, Article 263. https://doi.org/10.1186/1471-2105-7-263

Severinsen, J. E., Bjarkam, C. R., Kiaer-Larsen, S., Olsen, I. M., Nielsen, M. M., Blechingberg, J., Nielsen, A. L., Holm, I. E., Foldager, L., Young, B. D., Muir, W. J., Blackwood, D. H. R., Corydon, T. J., Mors, O. & Børglum, A. D. (2006). Evidence implicating BRD1 with brain development and susceptibility to both schizophrenia and bipolar affective disorder. Molecular Psychiatry, 11(12), 1126-38. https://doi.org/10.1038/sj.mp.4001885

Kammler, S., Otte, M., Hauber, I., Kjems, J., Hauber, J. & Schaal, H. (2006). The strength of the HIV-1 3' splice sites affects Rev function. Retrovirology, 3(89), 1-20. https://doi.org/10.1186/1742-4690-3-89

Dupont, D. M., Blouse, G. E., Hansen, M., Mathiasen, L., Kjelgaard, S., Jensen, J. K., Christensen, A., Gils, A., Declerck, P. J., Andreasen, P. A. & Wind, T. (2006). Evidence for a pre-latent form of the serpin plasminogen activator inhibitor-1 with a detached beta-strand 1C. Journal of Biological Chemistry, 281(47), 36071-81. https://doi.org/10.1074/jbc.M606851200

Skeldal, S., Larsen, J. V., Pedersen, K. E., Petersen, H. H., Egelund, R., Christensen, A., Jensen, J. K., Gliemann, J. & Andreasen, P. A. (2006). Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis. FEBS journal, 273(22), 5143-59. https://doi.org/10.1111/j.1742-4658.2006.05511.x

Walter, P., Klein, F., Lorentzen, E., Ilchmann, A., Klug, G. & Evguenieva-Hackenberg, E. (2006). Characterization of native and reconstituted exosome complexes from the hyperthermophilic archaeon Sulfolobus solfataricus. Mol. Microbiol., 62(4), 1076-1089.

Jensen, J. K., Malmendal, A., Schiøtt, B., Skeldal, S., Pedersen, K. E., Celik, L., Nielsen, N. C., Andreasen, P. A. & Wind, T. (2006). Inhibition of plasminogen activator inhibitor-1 binding to endocytosis receptors of the low-density-lipoprotein receptor family by a peptide isolated from a phage display library. Biochemical Journal, 399(3), 387-96. https://doi.org/10.1042/BJ20060533

Glémin, S., Vimond, L., Ronfort, J., Bataillon, T. & Mignot, A. (2006). Marker-based investigation of inbreeding depression in the endangered species Brassica insularis. Heredity, 97(4), 304-311. https://doi.org/10.1038/sj.hdy.6800870

Glerup, S., Kløverpris, S. & Oxvig, C. (2006). The proform of the eosinophil major basic protein binds the cell surface through a site distinct from its C-type lectin ligand-binding region. Journal of Biological Chemistry, 281(42), 31509-31516. https://doi.org/10.1074/jbc.M605824200

Kadarmideen, H. N., Li, Y. & Janss, L. C. G. (2006). Gene-environment interactions in complex diseases: Genetic models and methods for QTL mapping in multiple half-sib populations. Genetical Research, 88(2), 119-131. https://doi.org/10.1017/S0016672306008391

Fredslund, F., Jenner, L. B., Husted, L. B., Nyborg, J., Andersen, G. R. & Sottrup-Jensen, L. (2006). The structure of bovine complement component 3 reveals the basis for thioester function. Journal of Molecular Biology, 361(1), 115-127. https://doi.org/10.1016/j.jmb.2006.06.009

Bono, F., Ebert, J., Lorentzen, E. & Conti, E. (2006). The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA. Cell, 126(4), 713-725.

Lützelberger, M., Reinert, L. S., Das, A. T., Berkhout, B. & Kjems, J. (2006). A novel splice donor site in the gag-pol gene is required for HIV-1 RNA stability. Journal of Biological Chemistry, 281(27), 18644-18651. https://doi.org/10.1074/jbc.M513698200

Bergqvist, S., Croy, C. H., Kjærgaard, M., Huxford, T., Ghosh, G. & Komives, E. A. (2006). Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex. Journal of Molecular Biology, 360(2), 421-34. https://doi.org/10.1016/j.jmb.2006.05.014

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