Department of Molecular Biology and Genetics

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Latest peer-reviewed publications at MBG

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Peer-reviewed publications at MBG - all years

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Andersen, G., Poterszman, A., Egly, J. M., Moras, D. & Thierry, J. C. (1996). The crystal structure of human cyclin H. FEBS Letters, 397(1), 65-69. https://doi.org/10.1016/S0014-5793(96)01143-X
Kjøller, L., Martensen, P. M., Sottrup-Jensen, L., Justesen, J., Rodenburg, K. W. & Andreasen, P. A. (1996). Conformational changes of the reactive-centre loop and beta-strand 5A accompany temperature-dependent inhibitor-substrate transition of plasminogen-activator inhibitor 1. European Journal of Biochemistry, 241(1), 38-46.
Bataillon, T., David, J. L. & Schoen, D. J. (1996). Neutral genetic markers and conservation genetics: simulated germplasm collections. Genetics, 144(1), 409-17.
Jensen, S., Redwood, C. S., Jenkins, J. R., Andersen, A. H. & Hickson, I. D. (1996). Human DNA topoisomerases II alpha and II beta can functionally substitute for yeast TOP2 in chromosome segregation and recombination. Molecular and General Genetics, 252(1-2), 79-86.
Biersack, H., Jensen, S., Gromova, I., Nielsen, I. S., Westergaard, O. & Andersen, A. H. (1996). Active heterodimers are formed from human DNA topoisomerase II alpha and II beta isoforms. Proceedings of the National Academy of Sciences (PNAS), 93(16), 8288-93.
Jensen, S., Andersen, A. H., Kjeldsen, E., Biersack, H., Olsen, E. H. N., Andersen, T. B., Westergaard, O. & Jakobsen, B. K. (1996). Analysis of functional domain organization in DNA topoisomerase II from humans and Saccharomyces cerevisiae. Molecular and Cellular Biology, 16(7), 3866-77.
Andersen, G. R. & Nyborg, J. (1996). A Spreadsheet Approach to Automated Protein Crystallization. Journal of Applied Crystallography, 29(3), 236-240. https://doi.org/10.1107/S0021889895014750
Haaning, J., Oxvig, C., Overgaard, M. T., Ebbesen, P., Kristensen, T. & Sottrup-Jensen, L. (1996). Complete cDNA sequence of the preproform of human pregnancy-associated plasma protein-A. Evidence for expression in the brain and induction by cAMP. European Journal of Biochemistry, 237(1), 159-163. https://doi.org/10.1111/j.1432-1033.1996.0159n.x
Daggett, V., Li, A., Itzhaki, L. S., Otzen, D. E. & Fersht, A. R. (1996). Structure of the transition state for folding of a protein derived from experiment and simulation. Journal of Molecular Biology, 257(2), 430-440. https://doi.org/10.1006/jmbi.1996.0173
Boege, F., Straub, T., Kehr, A., Boesenberg, C., Christiansen, K., Andersen, A. H., Jakob, F. & Köhrle, J. (1996). Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I. Journal of Biological Chemistry, 271(4), 2262-70.
Fedosov, S., Petersen, T. E. & Nexø, E. (1996). Transcobalamin from cow milk: isolation and physico-chemical properties. Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology, 1292(1), 111-119. https://doi.org/10.1016/0167-4838(95)00173-5
Schoen, D. J., Morgan, M. T. & Bataillon, T. (1996). How does self-pollination evolve? Inferences from floral ecology and molecular genetic variation. Philosophical Transactions of the Royal Society B: Biological Sciences, 351(1345), 1281-1290. https://doi.org/10.1098/rstb.1996.0111
Valnickova, Z., Thøgersen, I., Christensen, S., Chu, C. T., Pizzo, S. V. & Enghild, J. J. (1996). Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein. Journal of Biological Chemistry, 271(22), 12937-43.
Derventzi, A., Gonos, E. S. & Rattan, S. (1996). Ageing and cancer - a struggle of tendencies. In S. I. S. Rattan & O. Toussaint (Eds.), Molecular Gerontology - Research Status and Strategies. (pp. 15-23). Plenum Publisher.
Lenfant, F., Mann, R. K., Thomsen, B., Ling, X. & Grunstein, M. (1996). All four core histone N-termini contain sequences required for the repression of basal transcription in yeast. EMBO Journal, 15, 3974-3985.
Nielsen, V. H., Bendixen, C. & Thomsen, B. (1996). APstI RFLP at the porcine gene encoding the catalytic alpha subunit of protein kinase CK2. Animal Genetics, 27, 373-374.
Rattan, S. (1996). Cellular ageing in vitro as the basis of understanding ageing in vivo. Facts and Research in Gerontology, 5, 7-17.
Christensen, J. H., Andersen, M. H., Rasmussen, J. T., Berglund, L. E. & Petersen, T. E. (1996). Characterization of glycoprotein PAS‑6/7 from membranes of bovine milk fat globules. FEBS journal, 240(3), 628-636.
Ito, A., Mukaiyama, A., Itoh, Y., Nagase, H., Thøgersen, I., Enghild, J. J., Sasaguri, Y. & Mori, Y. (1996). Degradation of interleukin 1beta by matrix metalloproteinases. Journal of Biological Chemistry, 271(25), 14657-60.
Norsgaard, H., Rattan, S. & Clark, B. F. C. (1996). Distinction between differentiation and senescence and the absence of increased apoptosis in human keratinocytes undergoing cellular aging in vitro. . Experimental Gerontology, 31, 563-570.
Merli, A., Brodersen, D. E., Morini, B., Chen, Z.-W., Durley, R. C. E., Scott Mathews, F., Davidson, V. L. & Rossi, G. L. (1996). Enzymatic and electron transfer activities in crystalline protein complexes. Journal of Biological Chemistry, 271(16), 9177-9180.
Barciszewski, J., Siboska, G., Pedersen, B. O., Rattan, S. & Clark, B. F. C. (1996). Evidence for the presence of kinetin in DNA and cell extracts. FEBS Letters, 393, 197-200.
Andersen, L. B., Lund, A., Kveiborg, M., Clark, B. F. C. & Rattan, S. (1996). From genes to functional gene products during ageing. In S. I. S. Rattan & O. Toussaint (Eds.), Molecular Gerontology - Research Status and Strategies. (pp. 53-73). Plenum Publisher.
Rattan, S. & Toussaint, O. (1996). From molecular gerontology to healthy old age. In S. I. S. Rattan & O. Toussaint (Eds.), Molecular Gerontology - Research Status and Strategies. (pp. 201-209). Plenum Publisher.
Mak, P., Enghild, J. J. & Dubin, A. (1996). Hamster antithrombin III: purification, characterization and acute phase response. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology, 115(1), 135-41.
Polekhina, G., Thirup, S., Kjeldgaard, M., Nissen, P., Lippmann, C. & Nyborg, J. (1996). Helix unwinding in the effector region of elongation factor EF-Tu-GDP. Structure, 4(10), 1141-51.
Oury, T. D., Crapo, J. D., Valnickova, Z. & Enghild, J. J. (1996). Human extracellular superoxide dismutase is a tetramer composed of two disulphide-linked dimers: a simplified, high-yield purification of extracellular superoxide dismutase. Biochemical Journal, 317 ( Pt 1), 51-7.
Gately, S., Twardowski, P., Stack, M. S., Patrick, M., Boggio, L., Cundiff, D. L., Schnaper, H. W., Madison, L., Volpert, O., Bouck, N., Enghild, J., Kwaan, H. C. & Soff, G. A. (1996). Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin. Cancer Research, 56(21), 4887-90.
Burke, J. R., Enghild, J. J., Martin, M. E., Jou, Y. S., Myers, R. M., Roses, A. D., Vance, J. M. & Strittmatter, W. J. (1996). Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. Nature Medicine, 2(3), 347-50.
Nielsen, K. L., Holtet, T. L., Etzerodt, M., Moestrup, S. K., Gliemann, J., Sottrup-Jensen, L. & Thøgersen, H. C. (1996). Identification of residues in alpha-macroglobulins important for binding to the alpha2-macroglobulin receptor/Low density lipoprotein receptor-related protein. Journal of Biological Chemistry, 271(22), 12909-12912.
Christensen, L., Wiborg Simonsen, A. C., Heegaard, C. W., Moestrup, S. K., Andersen, J. A. & Andreasen, P. (1996). Immunohistochemical localization of urokinase‑type plasminogen activator, type‑1 plasminogen activator inhibitor, urokinase receptor and alpha(2)‑macroglobulin receptor in human breast carcinomas. International Journal of Cancer, 66, 441-452.
Schierup, M. H. & Christiansen, F. (1996). Inbreeding and outbreeding in plants. Heredity, 77, 461-468.
Petersen, L. N., Mamenta, E. L., Stevnsner, T., Chaney, S. G. & Bohr, V. A. (1996). Increased gene specific repair of cisplatin induced interstrand crosslinks in cisplatin resistant cell lines, and studies on carrier ligand specificity. Carcinogenesis, 17(12), 2597-2602. https://doi.org/10.1093/carcin/17.12.2597
Rattan, S. & Clark, B. F. C. (1996). Intracellular protein synthesis, modifications and aging. Biochemical Society Transactions, 24, 1043-1049.
Kristensen, O., Reshetnikova, L., Nissen, P., Siboska, G., Thirup, S. & Nyborg, J. (1996). Isolation, crystallization and X-ray analysis of the quaternary complex of Phe-tRNA(Phe), EF-Tu, a GTP analog and kirromycin. FEBS Letters, 399(1-2), 59-62.
Jørgensen, H., Hokland, P., Jensen, A. W. & Hokland, M. (1996). Little evidence for clonal evolution of malignant haematopoietic cells following relapse after autologous bone marrow transplantation. European Journal of Haematology, 57(1), 25-32. https://doi.org/10.1111/j.1600-0609.1996.tb00485.x
Christensen, B. M., Sørensen, E. S., Højrup, P., Petersen, T. E. & Rasmussen, L. K. (1996). Localization of potential transglutaminase cross-linking sites in bovine caseins. Journal of Agricultural and Food Chemistry, 44(7), 1943-1947. https://doi.org/10.1021/jf9602131
Wiborg, O., Andersen, C., Knudsen, C. R., Clark, B. F. C. & Nyborg, J. (1996). Mapping Escherichia coli elongation factor Tu residues involved in binding of aminoacyl-tRNA. Journal of Biological Chemistry, 271(34), 20406-11.
Rattan, S. I. S. & Toussaint, O. (Eds.) (1996). Molecular Gerontology: Research Status and Strategies. In S. I. Rattan & O. Toussaint (Eds.), Molecular Gerontology: Research Status and Strategies Springer. https://doi.org/10.1007/978-1-4615-5889-7
Derventzi, A., Rattan, S. & Gonos, E. S. (1996). Molecular links between cellular mortality and immortality. Anticancer Research, 16, 2901-2910.
Berglund, L., Rasmussen, J. T., Andersen, M. D., Rasmussen, M. S. & Petersen, T. E. (1996). Purification of the Bovine Xanthine Oxidoreductase from Milk Fat Globule Membranes and Cloning of Complementary Deoxyribonucleic Acid. Journal of Dairy Science, 79(2), 198-204. https://doi.org/10.3168/jds.S0022-0302(96)76351-8
Knudsen, C. R. & Clark, B. F. C. (1996). Site-directed mutagenesis of Arg58 and Asp86 of elongation factor Tu from Escherichia coli: effects on the GTPase reaction and aminoacyl-tRNA binding. Protein Engineering, Design and Selection, 8(12), 1267-73.
Grøn, H., Thøgersen, I. B., Enghild, J. J. & Pizzo, S. V. (1996). Structural and functional analysis of the spontaneous re-formation of the thiol ester bond in human alpha 2-macroglobulin, rat alpha 1-inhibitor-3 and chemically modified derivatives. Biochemical Journal, 318 ( Pt 2), 539-45.
Nyborg, J., Nissen, P., Kjeldgaard, M., Thirup, S., Polekhina, G. & Clark, B. F. (1996). Structure of the ternary complex of EF-Tu: macromolecular mimicry in translation. Trends in Biochemical Sciences, 21(3), 81-2.
Zavizion, B., Heegaard, C. W., White, J. H., Cheli, F. & Politis, I. (1996). Synthesis of plasminogen activator inhibitor 1 by bovine mammary epithelial and myoepithelial cell lines. Journal of Dairy Research, 63, 451-458.
Rattan, S. & Riis, B. (1996). The antibiotic fusidic acid inhibits ADP-ribosylation of protein elongation factor-2 in human cells. Medical Science Research, 24, 221-222.
Nissen, P., Kjeldgaard, M., Thirup, S., Clark, B. F. & Nyborg, J. (1996). The ternary complex of aminoacylated tRNA and EF-Tu-GTP. Recognition of a bond and a fold. Biochimie, 78(11-12), 921-33.
De Prat Gay, G., Ruiz-Sanz, J., Neira, J. L., Corrales, F. J., Otzen, D. E., Ladurner, A. G. & Fersht, A. R. (1995). Conformational pathway of the polypeptide chain of chymotrypsin inhibitor-2 growing from its N terminus in vitro. Parallels with the protein folding pathway. Journal of Molecular Biology, 254(5), 968-979. https://doi.org/10.1006/jmbi.1995.0669
Petersen, L. N., Stevnsner, T. & Bohr, V. A. (1995). DNA repair in a UV resistant chinese hamster ovary cell line. Carcinogenesis, 16(12), 3075-3081. https://doi.org/10.1093/carcin/16.12.3075
Itzhaki, L. S., Otzen, D. E. & Fersht, A. R. (1995). The structure of the transition state for folding of chymotrypsin inhibitor 2 analysed by protein engineering methods: Evidence for a nucleation-condensation mechanism for protein folding. Journal of Molecular Biology, 254(2), 260-288. https://doi.org/10.1006/jmbi.1995.0616

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