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Department of Molecular Biology and Genetics

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Latest peer-reviewed publications at MBG

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Displaying results 3351 to 62 out of 62

Peer-reviewed publications at MBG - all years

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Macchi, F., Eisenkolb, M., Kiefer, H. & Otzen, D. (2012). The effect of osmolytes on protein fibrillation. International Journal of Molecular Sciences (Online), 13(3), 3801-3819. https://doi.org/10.3390/ijms13033801

Larsen, S. A., Kassem, M. & Rattan, S. (2012). Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells. Chemistry Central Journal, 6(18), 6-18. https://doi.org/10.1186/1752-153X-6-18

Hamming, O. J., Kang, L., Svensson, A., Karlsen, J. L., Rahbek-Nielsen, H., Paludan, S. R., Hjorth, S. A., Bondensgaard, K. & Hartmann, R. (2012). The crystal structure of the interleukin 21 receptor bound to interleukin 21 reveals that a sugar chain interacting with the WSXWS motif is an integral part of the interleukin 21 receptor. Journal of Biological Chemistry, 287, 9454-9460. https://doi.org/10.1074/jbc.M111.311084

Boskey, A. L., Christensen, B. S., Taleb, H. & Sørensen, E. S. (2012). Post-translational modification of osteopontin: Effects on in vitro hydroxyapatite formation and growth. Biochemical and Biophysical Research Communications, 419(2), 333-338. https://doi.org/10.1016/j.bbrc.2012.02.024

Larsen, E. K. U., Nielsen, T., Wittenborn, T., Rydtoft, L. M., Lokanathan, A. R., Hansen, L., Østergaard, L., Kingshott, P., Howard, K. A., Besenbacher, F., Nielsen, N. C. & Kjems, J. (2012). Accumulation of magnetic iron oxide nanoparticles coated with variably sized polyethylene glycol in murine tumors. Nanoscale, 4(7), 2352-2361 . https://doi.org/10.1039/C2NR11554A

Byskov, K., Jensen, N., Kongsfelt, I. B., Wielsøe, M., Pedersen, L. E., Haldrup, C. & Pedersen, L. (2012). Regulation of cell proliferation and cell density by the inorganic phosphate transporter PiT1. Cell Division, 7, 7. https://doi.org/10.1186/1747-1028-7-7

Gourdon, P., Sitsel, O., Karlsen, J. L., Møller, L. B. & Nissen, P. (2012). Structural models of the human copper P-type ATPases ATP7A and ATP7B. Biological Chemistry, 393(4), 205-216. https://doi.org/10.1515/hsz-2011-0249

Jiang, L., Sørensen, P., Thomsen, B., Høj-Edwards, S. M., Skarman, A., Røntved, C. M., Lund, M. S. & Workman, C. (2012). Gene prioritization for livestock diseases by data integration. Physiological Genomics, 44(5), 305-317. https://doi.org/10.1152/physiolgenomics.00047.2011

Rao, R. S. P. & Møller, I. M. (2012). Large-scale analysis of phosphorylation site occupancy in eukaryotic proteins. Biochimica et Biophysica Acta - Proteins and Proteomics, 1824(3), 405-412. https://doi.org/10.1016/j.bbapap.2011.12.001

Ghodke, S., Nielsen, S. B., Christiansen, G., Hjuler, H. A., Flink, J., Otzen, D. & Nielsen, S. B. (2012). Mapping out the multistage fibrillation of glucagon. FEBS journal, 279(5), 752-765. https://doi.org/10.1111/j.1742-4658.2011.08465.x

Bruhn, D., Møller, I. M., Mikkelsen, T. N. & Ambus, P. (2012). Terrestrial plant methane production and emission. Physiologia Plantarum, 144(3), 201-209. https://doi.org/10.1111/j.1399-3054.2011.01551.x

Kavaliauskas, D., Nissen, P. & Knudsen, C. R. (2012). The Busiest of All Ribosomal Assistants: Elongation Factor Tu. Biochemistry, 51(13), 2642-2651. https://doi.org/10.1021/bi300077s

Rattan, S. I. S. (2012). Cell senescence in vitro. In Encyclopedia of life sciences John Wiley & Sons Ltd. https://doi.org/10.1002/9780470015902.a0002567.pub3

Taschner, M., Bhogaraju, S. & Lorentzen, E. (2012). Architecture and function of IFT complex proteins in ciliogenesis. Differentiation, 83(2), 12-22.

Urbanski, D. F., Malolepszy, A., Stougaard, J. & Andersen, S. U. (2012). Genome-wide LORE1 retrotransposon mutagenesis and high-throughput insertion detection in Lotus japonicus. Plant Journal, 69(4), 731-741. https://doi.org/10.1111/j.1365-313X.2011.04827.x

Horton, M. W., Hancock, A. M., Huang, Y. S., Toomajian, C., Atwell, S., Auton, A., Muliyati, N. W., Platt, A., Sperone, F. G., Vilhjálmsson, B. J., Nordborg, M., Borevitz, J. O. & Bergelson, J. (2012). Genome-wide patterns of genetic variation in worldwide Arabidopsis thaliana accessions from the RegMap panel. Nature Genetics, 44(2), 212-6. https://doi.org/10.1038/ng.1042

Huang, H., Møller, I. M. & Song, S.-Q. (2012). Proteomics of desiccation tolerance during development and germination of maize embryos. Journal of Proteomics, 75(4), 1247-1262. https://doi.org/10.1016/j.jprot.2011.10.036

Jepsen, M., Beerens, N., Krüger, A. C., Kjems, J. & Birkedal, V. (2012). tRNA Annealing onto the HIV-1 Genome Studied by FRET Spectroscopy and Microscopy. Biophysical Journal, 102(3, Supplement 1), 278a . https://doi.org/10.1016/j.bpj.2011.11.1533

Villadsen, S. B., Bramsen, J. B., Ostenfeld, M. S., Wiklund, E. D., Fristrup, N., Gao, S., Hansen, T. B., Jensen, T. I., Borre, M., Orntoft, T. F., Dyrskjøt, L. & Kjems, J. (2012). The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer. B J C, 106(2), 366-374. https://doi.org/10.1038/bjc.2011.520

Gottfredsen, R. H., Tran, S. M.-H., Larsen, U. G., Madsen, P., Nielsen, M. S., Enghild, J. J. & Petersen, S. V. (2012). The C-terminal proteolytic processing of extracellular superoxide dismutase is redox regulated. Free Radical Biology & Medicine, 52(1), 191-197. https://doi.org/10.1016/j.freeradbiomed.2011.10.443

Abdallah, M. W., Hougaard, D. M., Grove, J., Nørgaard-Pedersen, B., Larsen, N., Bonefeld-Jørgensen, E. C. & Mortensen, E. L. (2012). The role of immune dysfunction in the pathopsychology of autism spectrum disorders: findings from a danish historic birth cohort. European Psychiatry, 27, 1-1. Article O-01. https://doi.org/10.1016/S0924-9338(12)74101-9

Mailund, T., Halager, A. E. & Westergaard, M. (2012). Using colored Petri nets to construct coalescent hidden markov models: Automatic translation from demographic specifications to efficient inference methods. Lecture Notes in Computer Science, 7347, 32-50. https://doi.org/10.1007/978-3-642-31131-4_3

Abdallah, M., Larsen, N., Grove, J., Nørgaard-Pedersen, B., Thorsen, P., Mortensen, E. L. & Hougaard, D. M. (2012). Amniotic Fluid Chemokines and Autism Spectrum Disorders: An Exploratory Study Utilizing a Danish Historic Birth Cohort. Brain, Behavior, and Immunity, 26(1), 170-176. https://doi.org/10.1016/j.bbi.2011.09.003

Greibe, E. H., Fedosov, S., Sørensen, B. S., Højrup, P., Poulsen, S. S. & Nexø, E. (2012). A Single Rainbow Trout Cobalamin-Binding Protein Stands in for Three Human Binders. Journal of Biological Chemistry, 287(40), 33917-33925.

Kjærgaard, M. & Poulsen, F. M. (2012). Disordered proteins studied by chemical shifts. Progress in Nuclear Magnetic Resonance Spectroscopy, 60, 42-51. https://doi.org/10.1016/j.pnmrs.2011.10.001

Ditte Caroline Andersen, D. C., Kristiansen, G. Q., Jensen, L., Füchtbauer, E.-M., Schrøder, H. D. & Jensen, C. H. (2012). Quantitative gene expression profiling of CD45⁺ and CD45^- skeletal muscle-derived side population cells. Cytometry. Part A, 81A(1), 72. https://doi.org/10.1002/cyto.a.21121

Dai, N., Foldager, L., Gallego, J. A., Hack, L. M., Ji, Y., Lett, T. A. P., Liu, B., Loken, E. K., Mandelli, L., Mehta, D., Power, R. A., Sprooten, E., Stephens, S. H., Paska, A. V., Yan, J., Zai, C. C., Zai, G., Zhang-James, Y., O'Shea, A. & DeLisi, L. E. (2012). Summaries from the XIX World Congress of Psychiatric Genetics, Washington, DC, September 10-14 2011. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 159B(1), 128-129. https://doi.org/10.1002/ajmg.b.32017

Wang, W.-Q., Cheng, H.-Y., Møller, I. M. & Song, S.-Q. (2012). The role of recovery of mitochondrial structure and function in desiccation tolerance of pea seeds. Physiologia Plantarum, 144(1), 20-34. https://doi.org/10.1111/j.1399-3054.2011.01518.x

Hansen, T. Ø., Sarup, P. M., Loeschcke, V. & Rattan, S. (2012). Age-related and sex-specific differences in proteasome activity in individual Drosophila flies from wild type, longevity-selected and stress resistant strains. Biogerontology, 13(4), 429-438. https://doi.org/10.1007/s10522-012-9387-2

Egerod, K. L., Engelstoft, M. S., Grunddal, K. V., Nøhr, M. K., Secher, A. E. L., Sakata, I., Pedersen, J., Windeløv, J. A., Füchtbauer, E.-M., Olsen, J., Sundler, F., Christensen, J. P., Wierup, N., Olsen, J. V., Holst, J. J., Zigman, J. M., Poulsen, S. S. & Schwartz, T. W. (2012). A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin. Contemporary Endocrinology, 153(12), 5782-5795. https://doi.org/10.1210/en.2012-1595

Kjærgaard, M., Poulsen, F. M. & Kragelund, B. B. (2012). Analyzing temperature-induced transitions in disordered proteins by NMR spectroscopy and secondary chemical shift analyses. Methods in molecular biology (Clifton, N.J.), 896, 249-56. https://doi.org/10.1007/978-1-4614-3704-8_16

Jin, X., He, M., Ferguson, B., Meng, Y., Ouyang, L., Ren, J., Mailund, T., Sun, F., Sun, L., Shen, J., Zhuo, M., Song, L., Wang, J., Ling, F., Zhu, Y., Hvilsom, C., Siegismund, H., Liu, X., Gong, Z. ... Wang, X. (2012). An effort to use human-based exome capture methods to analyze chimpanzee and macaque exomes. PLoS One, 7(7), e40637. https://doi.org/10.1371/journal.pone.0040637

Mailund, T., Halager, A. E., Westergaard, M., Dutheil, J. Y., Munch, K., Andersen, L. N., Lunter, G., Prüfer, K., Scally, A., Hobolth, A. & Schierup, M. H. (2012). A New Isolation with Migration Model along Complete Genomes Infers Very Different Divergence Processes among Closely Related Great Ape Species. PLoS Genetics, 8(12), e1003125. https://doi.org/10.1371/journal.pgen.1003125

Stukenbrock, E. H. & Bataillon, T. (2012). A population genomics perspective on the emergence and adaptation of new plant pathogens in agro-ecosystems. PLoS Pathogens, 8(9), e1002893. https://doi.org/10.1371/journal.ppat.1002893

Weber, M., Tome, L., Otzen, D. & Schneider, D. (2012). A Ser residue influences the structure and stability of a Pro-kinked transmembrane helix dimer. BBA General Subjects, 1818(9), 2103-7. https://doi.org/10.1016/j.bbamem.2012.04.003

Besenbacher, S., Mailund, T. & Schierup, M. H. (2012). Association mapping and disease: evolutionary perspectives. Methods in Molecular Biology, 856, 275-91. https://doi.org/10.1007/978-1-61779-585-5_11

Lubas, M. S., Chlebowski , A., Dziembowski , A. & Jensen, T. H. (2012). Biochemistry and Function of the RNA Exosomes. In G. F. Chanfreau & F. Tamanoi (Eds.), The Enzymes: Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis, Part A (Vol. 31, pp. 1-30). Elsevier. https://doi.org/10.1016/B978-0-12-404740-2.00001-X

Rattan, S. I. S. (2012). Biogerontology: from here to where? The Lord Cohen Medal Lecture-2011. Biogerontology, 13(1), 83-91. https://doi.org/10.1007/s10522-011-9354-3

Kadarmideen, H. N. & Watson-Haigh, N. S. (2012). Building gene co-expression networks using transcriptomics data for systems biology investigations: Comparison of methods using microarray data. Bioinformation, 8(18), 855-61. https://doi.org/10.6026/97320630008855

Ho-Huu, J., Ronfort, J., De Mita, S., Bataillon, T., Hochu, I., Weber, A. & Chantret, N. (2012). Contrasted patterns of selective pressure in three recent paralogous gene pairs in the Medicago genus (L.). BMC Evolutionary Biology, 12, 195. https://doi.org/10.1186/1471-2148-12-195

Lorentzen, E. & Conti, E. (2012). Crystal structure of a 9-subunit archaeal exosome in pre-catalytic states of the phosphorolytic reaction. Archaea, 2012, 721869.

Christensen, B. S., Kläning, E., Nielsen, M. S., Andersen, M. H. & Sørensen, E. S. (2012). C-terminal Modification of Osteopontin Inhibits Interaction with the αVβ3-Integrin. Journal of Biological Chemistry, 287, 3788-3797.

Elfving, B., Buttenschøn, H. N., Foldager, L., Poulsen, P. H. P., Andersen, J. H., Grynderup, M. B., Hansen, A. M., Kolstad, H. A., Kaerlev, L., Mikkelsen, S., Thomsen, J. F., Børglum, A. D., Wegener, G. & Mors, O. (2012). Depression, the Val66Met polymorphism, age, and gender influence the serum BDNF level. Journal of Psychiatric Research, 46(9), 1118-1125. https://doi.org/10.1016/j.jpsychires.2012.05.003

Bramsen, J. B. & Kjems, J. (2012). Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering. Frontiers in Genetics, 3, 154. https://doi.org/10.3389/fgene.2012.00154

Rasmussen, M. K., Zamaratskaia, G., Andersen, B. & Ekstrand, B. (2012). Dried chicory root modifies the activity and expression of porcine hepatic CYP3A but not 2C – Effect of in vitro and in vivo exposure. Food and Chemical Toxicology, 50(11), 4175-4179. https://doi.org/10.1016/j.fct.2012.08.024

Hayashi, Y., Engelmann, P., Foldbjerg, R., Szabó, M., Somogyi, I., Pollák, E., Molnár, L., Autrup, H., Sutherland, D. S., Scott-Fordsmand, J. J. & Heckmann, L.-H. (2012). Earthworms and Humans in Vitro: Characterizing Evolutionarily Conserved Stress and Immune Responses to Silver Nanoparticles. Environmental Science & Technology, 46, 4166-4173. https://doi.org/10.1021/es3000905

Gupta, V., Markmann, K., Pedersen, C. N. S., Stougaard, J. & Andersen, S. U. (2012). shortran: A pipeline for small RNA-seq data analysis. Bioinformatics, 28(20), 2698-2700. https://doi.org/10.1093/bioinformatics/bts496

Pedersen, C. N. S., Axelsen, K. B., Harper, J. F. & Palmgren, M. G. (2012). Evolution of plant P-type ATPases. Frontiers in Plant Science, 21. https://doi.org/10.3389/fpls.2012.00031

Ulrich, A., Andersen, K. R. & Schwartz, T. U. (2012). Exponential megapriming PCR (EMP) cloning-seamless DNA insertion into any target plasmid without sequence constraints. PLoS One, 7(12), e53360. https://doi.org/10.1371/journal.pone.0053360

Hvilsom, C., Qian, Y., Bataillon, T., Li, Y., Mailund, T., Sallé, B., Carlsen, F., Li, R., Zheng, H., Jiang, T., Jiang, H., Jin, X., Munch, K., Hobolth, A., Siegismund, H. R., Wang, J. & Schierup, M. H. (2012). Extensive X-linked adaptive evolution in central chimpanzees. Proceedings of the National Academy of Sciences (PNAS). https://doi.org/10.1073/pnas.1106877109

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Lisbeth Heilesen