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Latest peer-reviewed publications at MBG

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Displaying results 1501 to 63 out of 63

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Petersen, D., Reinholdt, P., Szomek, M., Hansen, S. K., Poongavanam, V., Dupont, A., Heegaard, C. W., Krishnan, K., Fujiwara, H., Covey, D. F., Ory, D. S., Kongsted, J. & Wüstner, D. (2020). Binding and intracellular transport of 25-hydroxycholesterol by Niemann-Pick C2 protein. Biochimica et biophysica acta - Biomembranes, 1862(2), Article 183063. https://doi.org/10.1016/j.bbamem.2019.183063

Rattan, S. (2020). Biological health and homeodynamic space. In Explaining Health Across the Sciences (pp. 43-51). Springer. https://doi.org/10.1007/978-3-030-52663-4_4

Liu, D., Geary, C. W., Chen, G., Shao, Y., Li, M., Mao, C., Andersen, E. S., Piccirilli, J. A., Rothemund, P. W. K. & Weizmann, Y. (2020). Branched kissing loops for the construction of diverse RNA homooligomeric nanostructures. Nature Chemistry, 12(3), 249-259. https://doi.org/10.1038/s41557-019-0406-7

Hodgson, K., Coleman, J. R. I., Hagenaars, S. P., Purves, K. L., Glanville, K., Choi, S. W., O'Reilly, P., Breen, G., Lewis, C. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2020). Cannabis use, depression and self-harm: phenotypic and genetic relationships. Addiction, 115(3), 482-492. https://doi.org/10.1111/add.14845

Haneke, K., Schott, J., Lindner, D., Hollensen, A. K., Damgaard, C. K., Mongis, C., Knop, M., Palm, W., Ruggieri, A. & Stoecklin, G. (2020). CDK1 couples proliferation with protein synthesis. The Journal of Cell Biology, 219(3), Article e201906147. https://doi.org/10.1083/jcb.201906147

Mazzoni, G., Pedersen, H. S., Rabaglino, M. B., Hyttel, P., Callesen, H. & Kadarmideen, H. (2020). Characterization of the endometrial transcriptome in early diestrus influencing pregnancy status in dairy cattle after transfer of in-vitro produced embryos. Physiological Genomics, 52(7), 269-279. https://doi.org/10.1152/physiolgenomics.00027.2020

Shuai, S., PCAWG Drivers and Functional Interpretation Working Group, Gallinger, S., Stein, L. & PCAWG Consortium (2020). Combined burden and functional impact tests for cancer driver discovery using DriverPower. Nature Communications, 11(1), Article 734. https://doi.org/10.1038/s41467-019-13929-1

Wang, X., Su, G., Hao, D., Lund, M. S. & Kadarmideen, H. N. (2020). Comparisons of improved genomic predictions generated by different imputation methods for genotyping by sequencing data in livestock populations. Journal of Animal Science and Biotechnology, 11(1), Article 3. https://doi.org/10.1186/s40104-019-0407-9

Hao, D., Wang, X., Thomsen, B., Kadarmideen, H. N., Wang, X., Lan, X., Huang, Y., Qi, X. & Chen, H. (2020). Copy number variations and expression levels of guanylate-binding protein 6 gene associated with growth traits of Chinese cattle. Animals, 10(4), Article 566. https://doi.org/10.3390/ani10040566

Duan, H., Mansour, S., Reed, R., Gillis, M. K., Parent, B., Liu, B., Sztupinszki, Z., Birkbak, N., Szallasi, Z., Elia, A. E. H., Garber, J. E. & Pathania, S. (2020). E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells. The Journal of Cell Biology, 219(6), Article e201908192. https://doi.org/10.1083/jcb.201908192

Laursen, N. S., Pedersen, D. V., Gytz, H., Zarantonello, A., Bernth Jensen, J. M., Hansen, A. G., Thiel, S. & Andersen, G. R. (2020). Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System. Frontiers in Immunology, 11, Article 1504. https://doi.org/10.3389/fimmu.2020.01504

Lloret-Llinares, M. & Jensen, T. H. (2020). Global Identification of Human Exosome Substrates Using RNA Interference and RNA Sequencing. In The Eukaryotic RNA Exosome: Methods and Protocols (pp. 127-145). Humana Press. https://doi.org/10.1007/978-1-4939-9822-7_7

Rattan, S. (2020). Homeostasis, homeodynamics and aging. In Encyclopedia of biomedical gerontology (pp. 238-241). Academic Press. https://doi.org/10.1016/B978-0-12-801238-3.11425-4

Rattan, S. (2020). Hormesis and hormetins in aging. In Encyclopedia of biomedical gerontology (pp. 242-250). Academic Press. https://doi.org/10.1016/B978-0-12-801238-3.11282-6

Sholl, J. & Rattan, S. I. S. (2020). How is ‘health’ explained across the sciences? conclusions and recapitulation. In J. Sholl & S. I. S. Rattan (Eds.), Explaining health across the sciences (pp. 541-549). Springer. https://doi.org/10.1007/978-3-030-52663-4_30

Hansen, S. F., Petrat-Melin, B., Rasmusen, J. T., Larsen, L. B. & Wiking, L. (2020). Impact of industrial cream heat treatments on the protein composition of the milk fat globule membrane. Journal of Dairy Research, 87(1), 89-93. https://doi.org/10.1017/S0022029919000955

Paczkowska, M., Barenboim, J., Sintupisut, N., Fox, N. S., Zhu, H., Abd-Rabbo, D., Mee, M. W., Boutros, P. C., PCAWG Drivers and Functional Interpretation Working Group, Reimand, J. & PCAWG Consortium (2020). Integrative pathway enrichment analysis of multivariate omics data. Nature Communications, 11(1), Article 735. https://doi.org/10.1038/s41467-019-13983-9

Barra, J., Gaidos, G. S., Blumenthal, E., Beckedorff, F., Tayar, M. M., Kirstein, N., Karakac, T. K., Jensen, T. H., Impens, F., Gevaert, K., Leucci, E., Shiekhattar, R. & Marine, J. C. (2020). Integrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1. Science Advances, 6(27), Article eaaz9072. https://doi.org/10.1126/sciadv.aaz9072

López, S., Lim, E. L., Horswell, S., Haase, K., Huebner, A., Dietzen, M., Mourikis, T. P., Watkins, T. B. K., Rowan, A., Dewhurst, S. M., Birkbak, N. J., Wilson, G. A., Van Loo, P., Jamal-Hanjani, M., TRACERx Consortium, Swanton, C. & McGranahan, N. (2020). Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution. Nature Genetics, 52(3), 283-293. https://doi.org/10.1038/s41588-020-0584-7

Briggs, D. C., Langford-Smith, A. W. W., Birchenough, H. L., Jowitt, T. A., Kielty, C. M., Enghild, J. J., Baldock, C., Milner, C. M. & Day, A. J. (2020). Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation. The Journal of Biological Chemistry, 295(16), 5278-5291. https://doi.org/10.1074/jbc.RA119.011916, https://doi.org/10.1074/jbc.RA119.011916

Sørensen, C. S. & Kjaergaard, M. (2020). Measuring Effective Concentrations Enforced by Intrinsically Disordered Linkers. In B. B. Kragelund & K. Skriver (Eds.), Methods in Molecular Biology: Methods and protocols (pp. 505-518). Humana Press. https://doi.org/10.1007/978-1-0716-0524-0_25

Kashyap, S., Hein, K. Z., Chini, C. C. S., Lika, J., Warner, G. M., Bale, L. K., Torres, V. E., Harris, P. C., Oxvig, C., Conover, C. A. & Chini, E. N. (2020). Metalloproteinase PAPP - A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis. JCI Insight, 5(4), Article e135700. https://doi.org/10.1172/jci.insight.135700

Petriman, N. A. & Lorentzen, E. (2020). Moving proteins along in the cilium. eLife, 9. https://doi.org/10.7554/eLife.55254

Martín-Encinas, E., Conejo-Rodríguez, V., Miguel, J. A., Martínez-Ilarduya, J. M., Rubiales, G., Knudsen, B. R., Palacios, F. & Alonso, C. (2020). Novel phosphine sulphide gold(i) complexes: topoisomerase I inhibitors and antiproliferative agents. Dalton Transactions, 49(23), 7852-7861. https://doi.org/10.1039/d0dt01467b

Garland, W. & Jensen, T. H. (2020). Nuclear sorting of RNA. Wiley Interdisciplinary Reviews: RNA, 11(2), Article e1572. https://doi.org/10.1002/wrna.1572

Østergaard, S., Krogh, M. A., Oliveira, V. H. S. D., Larsen, T., GplusE Consortium & Otten, N. D. (2020). Only few benefits from propylene glycol drench in early lactation for cows identified as physiologically imbalanced based on milk spectra analyses. Journal of Dairy Science, 103(2), 1831-1842. https://doi.org/10.3168/jds.2019-17205

Reyna, M. A., Haan, D., Paczkowska, M., Verbeke, L. P. C., Vazquez, M., Kahraman, A., Pulido-Tamayo, S., Barenboim, J., Wadi, L., Dhingra, P., Shrestha, R., Getz, G., Lawrence, M. S., Pedersen, J. S., Rubin, M. A., Wheeler, D. A., Brunak, S., Izarzugaza, J. M. G., Khurana, E. ... PCAWG Consortium (2020). Pathway and network analysis of more than 2500 whole cancer genomes. Nature Communications, 11(1), Article 729. https://doi.org/10.1038/s41467-020-14367-0

Privé, F., Luu, K., Vilhjálmsson, B. J. & Blum, M. G. B. (2020). Performing highly efficient genome scans for local adaptation with R package pcadapt version 4. Molecular Biology and Evolution, 37(7), 2153-2154. https://doi.org/10.1093/molbev/msaa053

Lewinska, A., Sodagam, L., Bloniarz, D., Siems, K., Wnuk, M. & Rattan, S. (2020). Plant-derived molecules α-boswellic acid acetate, praeruptorin-A and salvianolic acid-B have age-related differential effects in young and senescent human fibroblasts in vitro. Molecules, 25(1), Article 141. https://doi.org/10.3390/molecules25010141

Sochaj-Gregorczyk, A., Ksiazek, M., Waligorska, I., Straczek, A., Benedyk, M., Mizgalska, D., Thøgersen, I. B., Enghild, J. J. & Potempa, J. (2020). Plasmin inhibition by bacterial serpin: Implications in gum disease. The FASEB Journal, 34(1), 619-630. https://doi.org/10.1096/fj.201901490RR

Castellano, D. & Munch, K. (2020). Population Genomics in the Great Apes. In J. Y. Dutheil (Ed.), Methods in Molecular Biology (pp. 453-463). Springer. https://doi.org/10.1007/978-1-0716-0199-0_19

Nagaraj, M., Ahmed, M., Lyngsø, J., Vad, B. S., Bøggild, A., Fillipsen, A., Pedersen, J. S., Otzen, D. E. & Akbey, Ü. (2020). Predicted Loop Regions Promote Aggregation: A Study of Amyloidogenic Domains in the Functional Amyloid FapC. Journal of Molecular Biology, 432(7), 2232-2252. https://doi.org/10.1016/j.jmb.2020.01.044

van der Weijden, V. A., Hankele, A. K., Rehm, K., Bigler, L. & Ulbrich, S. E. (2020). Progestogen profiling in the European roe deer (Capreolus capreolus) during diapause and the reactivation period. Reproduction in Domestic Animals.

Bailey, M. H., Meyerson, W. U., Dursi, L. J., Wang, L. B., Dong, G., Liang, W. W., Weerasinghe, A., Li, S., Kelso, S., Akbani, R., Anur, P., Bailey, M. H., Buchanan, A., Chiotti, K., Covington, K., Creason, A., Ding, L., MC3 Working Group, PCAWG novel somatic mutation calling methods working group & PCAWG Consortium (2020). Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Nature Communications, 11(1), Article 4748. https://doi.org/10.1038/s41467-020-18151-y

Bhattacharya, S. & Rattan, S. (2020). Stress response pathways. In Encyclopedia of biomedical gerontology (pp. 282-289). Academic Press. https://doi.org/10.1016/B978-0-12-801238-3.11426-6

Hansen, B. K., Larsen, C. K., Nielsen, J. T., Svenningsen, E. B., Van, L. B., Jacobsen, K. M., Bjerring, M., Flygaard, R. K., Jenner, L. B., Nejsum, L. N., Brodersen, D. E., Mulder, F. A. A., Tørring, T. & Poulsen, T. B. (2020). Structure and Function of the Bacterial Protein Toxin Phenomycin. Structure, 28(5), 528-539.e9. https://doi.org/10.1016/j.str.2020.03.003

Andrzejczak, O. A., Havelund, J. F., Wang, W. Q., Kovalchuk, S., Hagensen, C. E., Hasler-Sheetal, H., Jensen, O. N., Rogowska-Wrzesinska, A., Møller, I. M. & Hebelstrup, K. H. (2020). The hypoxic proteome and metabolome of barley (Hordeum vulgare L.) with and without phytoglobin priming. International Journal of Molecular Sciences , 21(4), Article 1546. https://doi.org/10.3390/ijms21041546

Naseri, S., Steiniche, T., Georgsen, J. B., Thomsen, R., Ladekarl, M., Heje, M., Damsgaard, T. E. & Bønnelykke-Behrndtz, M. L. (2020). Tumor ulceration, reduced infiltration of CD8-lymphocytes, high neutrophil-to-CD8-lymphocyte ratio and absence of MC virus are negative prognostic markers for patients with merkel cell carcinoma. Cancers, 12(4), Article 888. https://doi.org/10.3390/cancers12040888

Klein, W. P., Thomsen, R. P., Turner, K. B., Walper, S. A., Vranish, J., Kjems, J., Ancona, M. G. & Medintz, I. L. (2019). Enhanced Catalysis from Multienzyme Cascades Assembled on a DNA Origami Triangle. ACS Nano, 13(12), 13677-13689. https://doi.org/10.1021/acsnano.9b05746

Chiriki, S., Verner Christiansen, M.-P. & Hammer, B. (2019). Constructing convex energy landscapes for atomistic structure optimization. Physical Review B, 100(23), Article 235436. https://doi.org/10.1103/PhysRevB.100.235436

Elfarrash, S., Jensen, N. M., Ferreira, N., Betzer, C., Thevathasan, J. V., Diekmann, R., Adel, M., Omar, N. M., Boraie, M. Z., Gad, S., Ries, J., Kirik, D., Nabavi, S. & Jensen, P. H. (2019). Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates. Acta Neuropathologica Communications, 7(1), Article 213. https://doi.org/10.1186/s40478-019-0865-5

Peña-Díaz, S., Pujols, J., Conde-Giménez, M., Čarija, A., Dalfo, E., García, J., Navarro, S., Pinheiro, F., Santos, J., Salvatella, X., Sancho, J. & Ventura, S. (2019). ZPD-2, a Small Compound That Inhibits α-Synuclein Amyloid Aggregation and Its Seeded Polymerization. Frontiers in Molecular Neuroscience, 12, Article 306. https://doi.org/10.3389/fnmol.2019.00306

Castellano, D., Eyre-Walker, A. & Munch, K. (2019). Impact of mutation rate and selection at linked sites on DNA variation across the genomes of humans and other homininae. Genome Biology and Evolution, 12(1), 3550-3561. https://doi.org/10.1093/gbe/evz215

Sullivan, A. R., Eldfjell, Y., Schiffthaler, B., Delhomme, N., Asp, T., Hebelstrup, K., Keech, O., Öberg, L., Møller, I. M., Arvestad, L., Street, N. R. & Wang, X.-R. (2019). The mitogenome of Norway spruce and a reappraisal of mitochondrial recombination in plants. Genome Biology and Evolution, 12(1), 3586-3598. https://doi.org/10.1093/gbe/evz263

Sørensen, C. S., Jendroszek, A. & Kjærgaard, M. (2019). Linker Dependence of Avidity in Multivalent Interactions between Disordered Proteins. Journal of Molecular Biology, 431(24), 4784-4795. https://doi.org/10.1016/j.jmb.2019.09.001

Privé, F., Vilhjálmsson, B. J., Aschard, H. & Blum, M. G. B. (2019). Making the Most of Clumping and Thresholding for Polygenic Scores. American Journal of Human Genetics, 105(6), 1213-1221. https://doi.org/10.1016/j.ajhg.2019.11.001

Bauer, A. E., Liu, X., Byrne, E. M., Sullivan, P. F., Wray, N. R., Agerbo, E., Nyegaard, M., Grove, J., Musliner, K. L., Ingstrup, K. G., Johannsen, B. M. W., Mægbæk, M. L., Wang, Y., Nordentoft, M., Mors, O., Børglum, A. D., Werge, T., Hougaard, D. M., Mortensen, P. B. ... Meltzer-Brody, S. (2019). Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders. Translational Psychiatry, 9(1), 288. Article 288. https://doi.org/10.1038/s41398-019-0629-9

Bonaventura, J., Eldridge, M. A. G., Hu, F., Gomez, J. L., Sanchez-Soto, M., Abramyan, A. M., Lam, S., Boehm, M. A., Ruiz, C., Farrell, M. R., Moreno, A., Galal Faress, I. M., Andersen, N., Lin, J. Y., Moaddel, R., Morris, P. J., Shi, L., Sibley, D. R., Mahler, S. V. ... Michaelides, M. (2019). High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nature Communications, 10(1), Article 4627. https://doi.org/10.1038/s41467-019-12236-z

Menges, L., Krawutschke, C., Füchtbauer, E. M., Füchtbauer, A., Sandner, P., Koesling, D. & Russwurm, M. (2019). Mind the gap (junction): cGMP induced by nitric oxide in cardiac myocytes originates from cardiac fibroblasts. British Journal of Pharmacology, 176(24), 4696-4707. https://doi.org/10.1111/bph.14835

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Revised 17.02.2026

Lisbeth Heilesen

Department of Molecular Biology and Genetics

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