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Latest peer-reviewed publications at MBG

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Displaying results 101 to 62 out of 62

Peer-reviewed publications at MBG - all years

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Hussein, A., Zhang, X., Pedersen, B. P. & Stokes, D. L. (2025). Conduction pathway for potassium through the Escherichia coli pump KdpFABC. eLife, 14. https://doi.org/10.7554/eLife.107397

Jansen, S. A. H., Dreyer, L. S. A., van Basten, J., Yao, Y., Otzen, D. E., de Greef, T. F. A., Knowles, T. P. J., Meijer, E. W. & Erkamp, N. A. (2025). PhaseXplorer Creates High-Dimensional Phase Diagrams with Closed-Loop Active Learning. ACS Nano, 19(45), 38981-38989. https://doi.org/10.1021/acsnano.5c07268

Talay, A., Belikov, A. V., To, P. K. P., Alfatemi, H. H., Alon, U., Deelen, J., Ewald, C. Y., Gems, D., Gorbunova, V., Gruber, J., Hägg, S., Hemming, J., Horvath, S., Kaya, A., Lewis, C. J., Maier, A. B., Marinova, M. B., Pawelec, G., Peleg, S. ... de Magalhães, J. P. (2025). Open problems in ageing science: a roadmap for biogerontology. GeroScience. Advance online publication. https://doi.org/10.1007/s11357-025-01964-4

Bærentsen, R. L., Kronborg, K., Brodersen, D. E. & Zhang, Y. E. (2025). Catalytic mechanism and differential alarmone regulation of a conserved stringent nucleosidase. Structure. Advance online publication. https://doi.org/10.1016/j.str.2025.10.012

Gabs, E., Aalto-Setälä, E., Välisaari, A., Malinen, A. M., Jensen, T. H., McLaughlin, S. H., Passmore, L. A. & Turtola, M. (2025). A kinetic ruler controls mRNA poly(A) tail length. Genes & Development, 39(21-22), 1377-1394. https://doi.org/10.1101/gad.352912.125

Muñoz-Juan, A., Laromaine, A., Yuste, V. J. & Dalfó, E. (2025). Assessing Gastrointestinal Motility in Caenorhabditis elegans RAC1/CED-10 Mutants as a Tool to Study Early Parkinson's Disease. Journal of Visualized Experiments, 2025(225), Article e69278. https://doi.org/10.3791/69278

Mishra, A., Golbek, T. W., Thomassen, A. B., Zuzic, L., Schmüser, L., Saeed, K. H., Madzharova, F., Nielsen, J., Schiøtt, B., Otzen, D. E. & Weidner, T. (2025). Pathological Folding of α-Synuclein on Polystyrene Nanoplastic Revealed by Sum Frequency Scattering and 2D Infrared Spectroscopy. The Journal of Physical Chemistry Letters, 16(45), 11893-11900. https://doi.org/10.1021/acs.jpclett.5c02526

Zhang, B.-C., Pedersen, A., Reinert, L. S., Li, Y., Narita, R., Idorn, M., Hu, L., Skouboe, M. K., Li, S., Maimaitili, M., Ding, X., Cong, Y., Zhao, J., Frémond, M.-L., Mikkelsen, K., Gao, Z., Huang, J.-R., Thomsen, E. A., Mikkelsen, J. H. ... Paludan, S. R. (2025). STING signals to NF-κB from late endolysosomal compartments using IRF3 as an adaptor. Nature Immunology, 26(11), 1916-1930. https://doi.org/10.1038/s41590-025-02283-8

Silale, A., Madej, M., Mikruta, K., Frey, A. M., Hart, A. J., Baslé, A., Scavenius, C., Enghild, J. J., Trost, M., Hirt, R. P. & van den Berg, B. (2025). Structure of a distinct β-barrel assembly machinery complex in the Bacteroidota. Nature Microbiology, 10(11), 2845-2859. https://doi.org/10.1038/s41564-025-02132-2

Pravata, V. M., Jiang, H., Ferenbach, A. T., Lamond, A. & van Aalten, D. M. F. (2025). Zscan4 as a Candidate Conveyor of Early Developmental Defects in O-GlcNAc Transferase Intellectual Disability. Molecular & Cellular Proteomics : MCP, 24(11), Article 101077. https://doi.org/10.1016/j.mcpro.2025.101077

Zhang, X., Grove, J., Gu, Y., Buus, C. K., Nielsen, L. K., Neufeld, S. A. S., Koko, M., Malawsky, D. S., Wade, E. M., Verhoef, E., Gui, A., Hegemann, L., Geschwind, D. H., Wray, N. R., Havdahl, A., Ronald, A., St Pourcain, B., Robinson, E. B., Bourgeron, T. ... APEX consortium (2025). Polygenic and developmental profiles of autism differ by age at diagnosis. Nature, 646(8087), 1146-1155. https://doi.org/10.1038/s41586-025-09542-6

Ramos Docampo, M. A., Abild Meyer, C., Ryberg, C., Otzen, D. E., Hirsch, C. & Städler, B. (2025). Actin Polymerizing Motors to Assist Cytoskeleton-like Networks Formation in Artificial Cells. ACS Nano, 19(42), 37324-37338. https://doi.org/10.1021/acsnano.5c12624

Castenschiold, C. D. F., Mignani, C., Christiansen, S., Alsved, M., Ickes, L., Tesson, S. V. M., Löndahl, J., Bilde, M., Bataillon, T., Finster, K. & Šantl-Temkiv, T. (2025). Atmospheric Biogenic Ice-Nucleating Particles Link to Microbial Communities in the Arctic Marine Environment in Western Greenland. Environmental Science and Technology, 59(42), 22518-22532. https://doi.org/10.1021/acs.est.5c03650

Teodori, L., Shahrokhtash, A., Sørensen, E. A., Zhang, X., Malle, M. G., Sutherland, D. S. & Kjems, J. (2025). Nanoscale Precise Stamping of Biomolecule Patterns Using DNA Origami. ACS Nano, 19(42), 36931-36942. https://doi.org/10.1021/acsnano.5c07651

Korsgaard, U., Kristensen, M. P., García-Rodríguez, J. L., Kjær-Frifeldt, S., Lindebjerg, J., Hansen, T. F., Kjems, J., Hager, H. & Kristensen, L. S. (2025). The prognostic potential of RNA in stage II colon cancer: Insights from a screened multicenter population-based cohort study. International Journal of Cancer, 157(8), 1746-1755. https://doi.org/10.1002/ijc.35507

Yadav, S. K., Kidmose, R. T. & Lorentzen, E. (2025). Intraflagellar transport: How kinesin motors hook onto their trains. Current Biology, 35(19), R928-R931. https://doi.org/10.1016/j.cub.2025.08.049

De Dios Andres, P., Purup, A. B., Beaune, G., Timonen, J. V. I., Lyons, J. A. & Städler, B. (2025). Flippase-Mediated Hybrid Vesicle Division. Advanced Materials, 37(39), Article 2504519. https://doi.org/10.1002/adma.202504519

Teixeira, L. M. C., Paiva, P., Ferreira, P., Rotilio, L., Morth, J. P., Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025). Bridging experiment and theory: a computational exploration of UMG-SP3 dynamics. Pure and Applied Chemistry, 97(10), 1405-1418. https://doi.org/10.1515/pac-2025-0489

Asenjo-Martinez, A., Dragicevic, K., Hou, W. H., Ozsvar, A., Winther Hansen, N., Pfisterer, U., Rydbirk, R., Demharter, S., Møller, B. E., Gasthaus, J., Korshunova, I., Perrier, J. F., Capogna, M., Vasistha, N. A. & Khodosevich, K. (2025). Dysfunction of cortical GABAergic projection neurons as a major hallmark in a model of neuropsychiatric syndrome. Neuron, 113(19), 3204-3223. https://doi.org/10.1016/j.neuron.2025.08.028

Segur-Bailach, E., Mateu-Bosch, A., Bofill-De Ros, X., Parés, M., da Silva Buttkus, P., Rathkolb, B., Gailus-Durner, V., Hrabě de Angelis, M., Moeini, P., Gonzalez-Aseguinolaza, G., Tort, F., Ribes, A., van Karnebeek, C. D. M., García-Villoria, J. & Fillat, C. (2025). Therapeutic AASS inhibition by AAV-miRNA rescues glutaric aciduria type I severe phenotype in mice. Molecular Therapy, 33(10), 4820-4833. https://doi.org/10.1016/j.ymthe.2025.07.022

Kapelyukh, Y., Gabel-Jensen, C., MacLeod, A. K., Daniel Coquelin, K. S., Stojanovski, L., Frame, L., Tavendale, A., Henderson, C. J., Read, K. D., Wolf, C. R. & Säll, C. (2025). Application of a mouse model humanized for cytochrome P450–mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs. Drug Metabolism and Disposition, 53(10), Article 100153. https://doi.org/10.1016/j.dmd.2025.100153

Søkilde, R., Kaadt, E., Kristensen, L. S., Venø, M. T., Kjems, J., Nyengaard, J. R., Nielsen, B. S. & Elfving, B. (2025). Application of microRNA In Situ Hybridization on Long-term Stored Human Formalin-fixed Paraffin-embedded Brain Samples from Psychiatric Patients. Molecular Neurobiology, 62(10), 12736-12746. https://doi.org/10.1007/s12035-025-05077-z

Kofod Petersen, A., Mânica, S., Forgie, A., Boyle, R., Pandey, H., Villesen, P. & Staun Larsen, L. (2025). Charred or fragmented, yet comparable: Quantifying dental surface dissimilarity across teeth, jaws, and heat exposure. Forensic Science International, 375, Article 112577. https://doi.org/10.1016/j.forsciint.2025.112577

Dardani, C., Robinson, J. W., Jones, H. J., Rai, D., Stergiakouli, E., Grove, J., Gardner, R., McIntosh, A. M., Havdahl, A., Hemani, G., Davey Smith, G., Richardson, T. G., Gaunt, T. R. & Khandaker, G. M. (2025). Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions. Molecular Psychiatry, 30(10), 4487-4496. Article e1004092. https://doi.org/10.1038/s41380-025-03032-x

Pinheiro, F., Nowak, J. S., Zueva, E., Pheasant, E. C., Grene, I. K., Lampinen, V. & Kjaergaard, M. (2025). Screening de novo designed protein binders in unpurified lysate using flow induced dispersion analysis. Protein Science, 34(10), Article e70286. https://doi.org/10.1002/pro.70286

Bro̷chner, B. V., Zhang, X., Nielsen, J., Kjems, J., Otzen, D. E. & Malle, M. G. (2025). Single-vesicle Tracking of α-Synuclein Oligomers Reveals Pore Formation by a Three-Stage Model. ACS Nano, 19(36), 32108-32122. https://doi.org/10.1021/acsnano.5c04005

Buhl, J. M., Mahapatra, S., Kjærgaard, M. & Mulder, F. A. A. (2025). Quantification of Small Molecule Partitioning in a Biomolecular Condensate with 2D Nuclear Magnetic Resonance Spectroscopy. ChemBioChem, 26(17), Article e202500401. https://doi.org/10.1002/cbic.202500401

Hollensen, A. K., Sørensen, M. H., Thomsen, S. V., Thomsen, H. S. & Damgaard, C. K. (2025). Using circular RNAs to target toxic RNA-binding proteins in amyotrophic lateral sclerosis. Molecular Therapy Methods and Clinical Development, 33(3), Article 101525. https://doi.org/10.1016/j.omtm.2025.101525

Zimmer, F., Fox, A. M., Pan, Q., Rühle, F., Andersen, P., Huylmans, A. K., Schwander, T., Basilicata, M. F. & Keller Valsecchi, C. I. (2025). Convergent evolution of H4K16ac-mediated dosage compensation in the ZW species Artemia franciscana. PLoS Genetics, 21(10), Article e1011895. https://doi.org/10.1371/journal.pgen.1011895

Mishra, A., Golbek, T. W., Zubia-Aranburu, J., Madzharova, F., Drace, T., Bøggild, A., Boesen, T., Saeed, K. H., Klausen, L. H., Dong, M., Roeters, S. J. & Weidner, T. (2025). Polystyrene Nanoplastic Contaminants Denature Human Apolipoprotein A-1. Nano Letters, 25(35), 13160-13165. https://doi.org/10.1021/acs.nanolett.5c02743

Salasova, A. & Nykjær, A. (2025). Emerging potential of progranulin-dependent SorCS2 signaling in healthy and diseased nervous systems. Neural Regeneration Research, 20(9), 2591-2593. https://doi.org/10.4103/NRR.NRR-D-24-00734

Stenberg, K., Korhonen, S., Seemab, U., Dupont, D. M., Kjems, J., Honkakoski, P. & Subrizi, A. (2025). Selection of locally administered ocular tissue-targeting RNA aptamers using in vivo SELEX. European Journal of Pharmaceutical Sciences, 212, Article 107217. https://doi.org/10.1016/j.ejps.2025.107217

Lousdal, M. L., LaBianca, S., Agerbo, E., Albiñana, C., Vilhjálmsson, B. J., McGrath, J. J., Schork, A. J. & Plana-Ripoll, O. (2025). Changes in polygenic burden for psychiatric disorders across two decades of birth cohorts. Nature Mental Health, 3(9), 1037-1045. https://doi.org/10.1038/s44220-025-00478-4

Kobek-Kjeldager, C., Jensen, L. D., Foldager, L., Kaiser, M., Thodberg, K. & Herskin, M. S. (2025). Deck height did not affect behavioural measures of ‘natural movements’ and ‘adequate ventilation’ during 8 h and 23 h transport of weaner pigs. Applied Animal Behaviour Science, 290, Article 106714. https://doi.org/10.1016/j.applanim.2025.106714

Birkbak, N. J. & TRACERx Consortium (2025). DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution. Nature Genetics, 57(9), 2226-2237. https://doi.org/10.1038/s41588-025-02307-x

Mouritzen, T. W., Meurer, K. H. E., Bornhofen, E., Janss, L., Weih, M. & Andersen, S. U. (2025). Faba bean genetics and crop growth models – progress to date and opportunities for integration. Plant and Soil, 514(1), 47-64. https://doi.org/10.1007/s11104-025-07459-7

Rasmussen, M. Q., Bønnelykke-Behrndtz, M. L., Merrild, C., Tvilling, I. K. S., Christensen, J. N., Nielsen, M. M., Georgsen, J. B., Naumann, N., Gudbergsson, J. M., Etzerodt, A., Pedersen, J. S., Jenkins, R. W., Degn, S. E., Moestrup, S. K., Schmidt, H., Steiniche, T. & Madsen, M. (2025). LRP2 Expression in Melanoma Is Associated With a Transitory Cell State, Increased T Cell Infiltration, and Is Upregulated by IFNy Signaling. Pigment Cell & Melanoma Research, 38(5), Article e70053. https://doi.org/10.1111/pcmr.70053

Smit, R. A. J., Wade, K. H., Hui, Q., Arias, J. D., Yin, X., Christiansen, M. R., Yengo, L., Preuss, M. H., Nakabuye, M., Rocheleau, G., Graham, S. E., Buchanan, V. L., Chittoor, G., Graff, M., Guindo-Martínez, M., Lu, Y., Marouli, E., Sakaue, S., Spracklen, C. N. ... VA Million Veteran Program (2025). Polygenic prediction of body mass index and obesity through the life course and across ancestries. Nature Medicine, 31(9), 3151-3168. https://doi.org/10.1038/s41591-025-03827-z