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Latest peer-reviewed publications at MBG

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Displaying results 1601 to 63 out of 63

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Rasmussen, M. K., Scavenius, C., Gerbal-Chaloin, S. & Enghild, J. (2019). Sex dictates the constitutive expression of hepatic cytochrome P450 isoforms in Göttingen minipigs. Toxicology Letters, 314, 181-186. https://doi.org/10.1016/j.toxlet.2019.08.008

Møhlenberg, M., Gad, H. H. & Hartmann, R. (2019). The Influence of the rs30461 Single Nucleotide Polymorphism on IFN-λ1 Activity and Secretion. Journal of Interferon & Cytokine Research, 39(10), 661-667. https://doi.org/10.1089/jir.2019.0051

Musliner, K., Vilhjálmsson, B. J., Albiñana Climent, C., Krebs, M. D., Zandi, P. P., Agerbo, E., Mortensen, P. B., Werge, T., Børglum, A. & Østergaard, S. D. (2019). Towards precision medicine in psychiatric care: Using polygenic risk scores to predict outcomes in hospital-treated depression patients . S88-S88. Abstract from World Congress of Psychiatric Genetics , Anaheim , California, United States.

Kjeldsen, K. U., Schreiber, L., Thorup, C. A., Boesen, T., Bjerg, J. T., Yang, T., Dueholm, M. S., Larsen, S., Risgaard-Petersen, N., Nierychlo, M., Schmid, M., Bøggild, A., van de Vossenberg, J., Geelhoed, J. S., Meysman, F. J. R., Wagner, M., Nielsen, P. H., Nielsen, L. P. & Schramm, A. (2019). On the evolution and physiology of cable bacteria. Proceedings of the National Academy of Sciences (PNAS), 116(38), 19116-19125. https://doi.org/10.1073/pnas.1903514116

Wang, S., Chavez, A. D., Thomas, S., Li, H., Flanders, N. C., Sun, C., Strauss, M. J., Chen, L. X., Markvoort, A. J., Bredas, J. L. & Dichtel, W. R. (2019). Pathway Complexity in the Stacking of Imine-Linked Macrocycles Related to Two-Dimensional Covalent Organic Frameworks. Chemistry of Materials, 31(17), 7104-7111. https://doi.org/10.1021/acs.chemmater.9b03088

Meyer, R. L., Walther, R., Nielsen, S. M., Andersen, P. O., Hansen, L., Vu-Quang, H., Kjems, J. & Zelikin, A. N. (2019). Delivering antibiotics locally to biofilms by targeted drug delivery and prodrug therapy. Abstract from Eurobiofilms 2019, Glasgow, United Kingdom.

Heitzeneder, S., Sotillo, E., Shern, J. F., Sindiri, S., Xu, P., Jones, R., Pollak, M., Noer, P. R., Lorette, J., Fazli, L., Alag, A., Meltzer, P., Lau, C., Conover, C. A., Oxvig, C., Sorensen, P. H., Maris, J. M., Khan, J. & Mackall, C. L. (2019). Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion. Journal of the National Cancer Institute, 111(9), 970-982. Article 209. https://doi.org/10.1093/jnci/djy209

Bærentsen, R. L., Brodersen, D. E. & Zhang, Y. E. (2019). Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response. Microbial Cell, 6(9), 450-453. https://doi.org/10.15698/mic2019.09.692

Meier, S. M., Trontti, K., Purves, K. L., Als, T. D., Grove, J., Laine, M., Pedersen, M. G., Bybjerg-Grauholm, J., Bækved-Hansen, M., Sokolowska, E., Mortensen, P. B., Hougaard, D. M., Werge, T., Nordentoft, M., Breen, G., Børglum, A. D., Eley, T. C., Hovatta, I., Mattheisen, M. & Mors, O. (2019). Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study. J A M A Psychiatry, 76(9), 924-932. https://doi.org/10.1001/jamapsychiatry.2019.1119

Hübel, C., Gaspar, H. A., Coleman, J. R. I., Finucane, H., Purves, K. L., Hanscombe, K. B., Prokopenko, I., Graff, M., Ngwa, J. S., Workalemahu, T., O'Reilly, P. F., Bulik, C. M., Breen, G., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Tourette Syndrome/Obsessive-Compulsive Disorder Working Group of the Psychiatric Genomics Consortium, MAGIC Investigators & Eating Disorders Working Group of the Psychiatric Genomics Consortium (2019). Genomics of body fat percentage may contribute to sex bias in anorexia nervosa. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 180(6), 428-438. https://doi.org/10.1002/ajmg.b.32709

Verboom, K., Everaert, C., Bolduc, N., Livak, K. J., Yigit, N., Rombaut, D., Anckaert, J., Lee, S., Venø, M. T., Kjems, J., Speleman, F., Mestdagh, P. & Vandesompele, J. (2019). SMARTer single cell total RNA sequencing. Nucleic Acids Research, 47(16), Article e93. https://doi.org/10.1093/nar/gkz535

Martín-Encinas, E., Rubiales, G., Knudssen, B. R., Palacios, F. & Alonso, C. (2019). Straightforward synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents of hybrid Chromeno[4,3-b][1,5]Naphthyridines and Chromeno[4,3-b][1,5]Naphthyridin-6-ones. European Journal of Medicinal Chemistry, 178, 752-766. https://doi.org/10.1016/j.ejmech.2019.06.032

Duszynska, D., Vilhjalmsson, B., Castillo Bravo, R., Swamidatta, S., Juenger, T. E., Donoghue, M. T. A., Comte, A., Nordborg, M., Sharbel, T. F., Brychkova, G., McKeown, P. C. & Spillane, C. (2019). Transgenerational effects of inter-ploidy cross direction on reproduction and F2 seed development of Arabidopsis thaliana F1 hybrid triploids. Plant Reproduction, 32(3), 275-289. https://doi.org/10.1007/s00497-019-00369-6

O'Brien, T. R., Hartmann, R. & Prokunina-Olsson, L. (2019). What makes the hepatitis C virus evolve? eLife, 8, Article e50148. https://doi.org/10.7554/eLife.50148

Alam, P., Bousset, L., Melki, R. & Otzen, D. E. (2019). α-synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities. Journal of Neurochemistry, 150(5), 522-534. https://doi.org/10.1111/jnc.14808

Karlsson, E., Andersson, E., Jones, N. C., Hoffmann, S. V., Jemth, P. & Kjærgaard, M. (2019). Coupled Binding and Helix Formation Monitored by Synchrotron-Radiation Circular Dichroism. Biophysical Journal, 117(4), 729-742. https://doi.org/10.1016/j.bpj.2019.07.014

Dupont, M. A., Humbert, C., Huber, C., Siour, Q., Guerrera, I. C., Jung, V., Christensen, A., Pouliet, A., Garfa-Traore, M., Nitschké, P., Injeyan, M., Millar, K., Chitayat, D., Shannon, P., Girisha, K. M., Shukla, A., Mechler, C., Lorentzen, E., Benmerah, A. ... Delous, M. (2019). Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion. Human Molecular Genetics, 28(16), 2720-2737. https://doi.org/10.1093/hmg/ddz091

Yang, A., Bofill-De Ros, X., Shao, T. J., Jiang, M., Li, K., Villanueva, P., Dai, L. & Gu, S. (2019). 3′ Uridylation Confers miRNAs with Non-canonical Target Repertoires. Molecular Cell, 75(3), 511-522.e4. https://doi.org/10.1016/j.molcel.2019.05.014

ElMaghraby, M. F., Andersen, P. R., Pühringer, F., Hohmann, U., Meixner, K., Lendl, T., Tirian, L. & Brennecke, J. (2019). A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production. Cell, 178(4), 964-979.e20. https://doi.org/10.1016/j.cell.2019.07.007

Song, P., Yang, C., Thomsen, J. S., Dagnaes-Hansen, F., Jakobsen, M., Bruel, A., Deleuran, B. & Kjems, J. (2019). Lipidoid-siRNA Nanoparticle-Mediated IL-1 beta Gene Silencing for Systemic Arthritis Therapy in a Mouse Model. Molecular Therapy, 27(8), 1424-1435. https://doi.org/10.1016/j.ymthe.2019.05.002

Bavafaye Haghighi, E., Knudsen, M., Laursen, B. E. & Besenbacher, S. (2019). Hierarchical classification of cancers of unknown primary using multi-omics data. Cancer Informatics, 18. https://doi.org/10.1177/1176935119872163

Jiang, M., Liu, Y., Li, R., Zheng, Y., Fu, H., Tan, Y., Moller, I. M., Fan, L., Shu, Q. & Huang, J. (2019). A Suppressor Mutation Partially Reverts the xantha Trait via Lowered Methylation in the Promoter of Genomes Uncoupled 4 in Rice. Frontiers in Plant Science, 10, Article 1003. https://doi.org/10.3389/fpls.2019.01003

Nadzieja, M., Stougaard, J. & Reid, D. (2019). A Toolkit for High Resolution Imaging of Cell Division and Phytohormone Signaling in Legume Roots and Root Nodules. Frontiers in Plant Science, 10, Article 1000. https://doi.org/10.3389/fpls.2019.01000

Anorexia Nervosa Genetics Initiative (2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics, 51(8), 1207-1214. https://doi.org/10.1038/s41588-019-0439-2

Hebelstrup, K. H. & Møller, I. M. (2019). Oxygen: Friend and foe! Biochemist, 41(4), 18-21. https://doi.org/10.1042/bio04104018

Tataru, P. & Bataillon, T. (2019). polyDFEv2.0: testing for invariance of the distribution of fitness effects within and across species. Bioinformatics (Oxford, England), 35(16), 2868-2869. https://doi.org/10.1093/bioinformatics/bty1060

Pedersen, D. V., Gadeberg, T. A. F., Thomas, C., Joram, N., Jensen, R. K., Mazarakis, S. M. M., Revel, M., El Sissy, C., Petersen, S. V., Lindorff-Larsen, K., Thiel, S., Laursen, N. S., Fremeaux-Bacchi, V. & Andersen, G. R. (2019). Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Frontiers in Immunology, 10, Article 2007. https://doi.org/10.3389/fimmu.2019.02007

Poulsen, E. T., Nielsen, N. S., Scavenius, C., Mogensen, E. H., Risør, M. W., Runager, K., Lukassen, M. V., Rasmussen, C. B., Christiansen, G., Richner, M., Vorum, H. & Enghild, J. J. (2019). The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation. Journal of Biological Chemistry, 294(31), 11817-11828. https://doi.org/10.1074/jbc.RA119.009050

Gerring, Z. F., Gamazon, E. R., Derks, E. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2019). A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression. PLoS Genetics, 15(7), e1008245. Article e1008245. https://doi.org/10.1371/journal.pgen.1008245

Griffiths, A. G., Moraga, R., Tausen, M., Gupta, V., Bilton, T. P., Campbell, M. A., Ashby, R., Nagy, I., Khan, A., Larking, A., Anderson, C., Franzmayr, B., Hancock, K., Scott, A., Ellison, N. W., Cox, M. P., Asp, T., Mailund, T., Schierup, M. H. & Andersen, S. U. (2019). Breaking Free: The Genomics of Allopolyploidy-Facilitated Niche Expansion in White Clover. The Plant Cell, 31(7), 1466-1487. https://doi.org/10.1105/tpc.18.00606

Mikkelsen, K., Lykke Harwood, S., Compte, M., Merino, N., Molgaard, K., Lykkemark, S., Alvarez-Mendez, A., Blanco, F. J. & Alvarez-Vallina, L. (2019). Carcinoembryonic Antigen (CEA)-Specific 4-1BB-Costimulation Induced by CEA-Targeted 4-1BB-Agonistic Trimerbodies. Frontiers in Immunology, 10, 1791. Article 1791. https://doi.org/10.3389/fimmu.2019.01791

Calabrese, E. J., Dhawan, G., Mattson, M. P. & Rattan, S. (2019). Curcumin and hormesis with particular emphasis on neural cells. Food and Chemical Toxicology, 129, 399-404. https://doi.org/10.1016/j.fct.2019.04.053

Nielsen, T. B., Thomsen, R. P., Mortensen, M. R., Kjems, J., Nielsen, P. F., Nielsen, T. E., Kodal, A. L. B., Cló, E. & Gothelf, K. V. (2019). Peptide-Directed DNA-Templated Protein Labelling for The Assembly of a Pseudo-IgM. Angewandte Chemie International Edition, 58(27), 9068-9072. https://doi.org/10.1002/anie.201903134

GERAD1 Consortium: (2019). Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 51(7), 1193-1193. https://doi.org/10.1038/s41588-019-0450-7

Timcenko, M., Lyons, J. A., Januliene, D., Ulstrup, J. J., Dieudonné, T., Montigny, C., Ash, M. R., Karlsen, J. L., Boesen, T., Kühlbrandt, W., Lenoir, G., Moeller, A. & Nissen, P. (2019). Structure and autoregulation of a P4-ATPase lipid flippase. Nature, 571(7765), 366-370. https://doi.org/10.1038/s41586-019-1344-7

Jamal, A., Sato, Y., Shahi, S., Shamsi, W., Kondo, H. & Suzuki, N. (2019). Novel Victorivirus from a Pakistani Isolate of Alternaria alternata Lacking a Typical Translational Stop/Restart Sequence Signature. Viruses, 11(6). https://doi.org/10.3390/v11060577

Grelet, C., Froidmont, E., Hostens, M., Foldager, L., Salavati, M., Vanlierde, A., Sørensen, M. T., Ingvartsen, K. L., Crowe, M., Ferris, C. P., GplusE Consortium & Dehareng, F. (2019). A first approach to predict nitrogen efficiency of individual dairy cows through milk MIR spectra. Poster session presented at ICAR 2019, Prag, Czech Republic.

Richner, M., Pallesen, L. T., Ulrichsen, M., Poulsen, E. T., Holm, T. H., Login, H., Castonguay, A., Lorenzo, L.-E., Gonçalves, N. P., Andersen, O. M., Lykke-Hartmann, K., Enghild, J. J., Rønn, L. C. B., Malik, I. J., De Koninck, Y., Bjerrum, O. J., Vægter, C. B. & Nykjær, A. (2019). Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain. Science Advances, 5(6), Article eaav9946. https://doi.org/10.1126/sciadv.aav9946

Vang Nielsen, S., Turnbull, K. J., Roghanian, M., Bærentsen, R., Semanjski, M., Brodersen, D. E., Macek, B. & Gerdes, K. (2019). Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase. mBio, 10(3), Article e01138-19. https://doi.org/10.1128/mBio.01138-19

Drews, B., Rudolf Vegas, A., van der Weijden, V. A., Milojevic, V., Hankele, A. K., Schuler, G. & Ulbrich, S. E. (2019). Do ovarian steroid hormones control the resumption of embryonic growth following the period of diapause in roe deer (Capreolus capreolus)? Reproductive Biology, 19(2), 149-157. https://doi.org/10.1016/j.repbio.2019.04.003

Bechsgaard, J., Schou, M. F., Vanthournout, B., Hendrickx, F., Knudsen, B., Settepani, V., Schierup, M. H. & Bilde, T. (2019). Evidence for Faster X Chromosome Evolution in Spiders. Molecular Biology and Evolution, 36(6), 1281-1293. https://doi.org/10.1093/molbev/msz074

Stronen, A. V., Pertoldi, C., Iacolina, L., Kadarmideen, H. N. & Kristensen, T. N. (2019). Genomic analyses suggest adaptive differentiation of northern European native cattle breeds. Evolutionary Applications, 12(6), 1096-1113. https://doi.org/10.1111/eva.12783

Trebeschi, S., Drago, S. G., Birkbak, N. J., Kurilova, I., Cǎlin, A. M., Delli Pizzi, A., Lalezari, F., Lambregts, D. M. J., Rohaan, M. W., Parmar, C., Rozeman, E. A., Hartemink, K. J., Swanton, C., Haanen, J. B. A. G., Blank, C. U., Smit, E. F., Beets-Tan, R. G. H. & Aerts, H. J. W. L. (2019). Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers. Annals of Oncology, 30(6), 998-1004. Article mdz108. https://doi.org/10.1093/annonc/mdz108

Flygaard, R. K., Malacrida, B., Kiely, P. & Jenner, L. B. (2019). Purification and characterization of native human elongation factor 2. Protein Expression and Purification, 158, 15-19. https://doi.org/10.1016/j.pep.2019.02.005

Raniolo, S., Croce, S., Thomsen, R. P., Okholm, A. H., Unida, V., Iacovelli, F., Manetto, A., Kjems, J., Desideri, A. & Biocca, S. (2019). Cellular uptake of covalent and non-covalent DNA nanostructures with different sizes and geometries. Nanoscale, 11(22), 10808-10818. https://doi.org/10.1039/c9nr02006c

Ferrando, B., Furlanetto, A. L. D. M., Gredilla, R., Havelund, J. F., Hebelstrup, K. H., Møller, I. M. & Stevnsner, T. (2019). DNA repair in plant mitochondria - a complete base excision repair pathway in potato tuber mitochondria. Physiologia Plantarum, 166(2), 494-512. https://doi.org/10.1111/ppl.12801

Demontis, D., Rajagopal, V. M., Thorgeirsson, T. E., Als, T. D., Grove, J., Leppälä, K., Gudbjartsson, D. F., Pallesen, J., Hjorthøj, C., Reginsson, G. W., Tyrfingsson, T., Runarsdottir, V., Qvist, P., Christensen, J. H., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Huckins, L. M., Stahl, E. A., Timmermann, A. ... Børglum, A. D. (2019). Genome-wide association study implicates CHRNA2 in cannabis use disorder. Nature Neuroscience, 22, 1066-1074. https://doi.org/10.1038/s41593-019-0416-1

Zhang, Y., Gal, N., Itel, F., Westensee, I. N., Brodszkij, E., Mayer, D., Stenger, S., Castellote-Borrell, M., Boesen, T., Tabaei, S. R., Hook, F. & Stadler, B. (2019). Hybrid vesicles as intracellular reactive oxygen species and nitric oxide generators. Nanoscale, 11(24), 11530-11541. https://doi.org/10.1039/c9nr02584g

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O'Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C. ... Binder, E. B. (2019). Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. Nature Communications, 10, Article 2548. https://doi.org/10.1038/s41467-019-10461-0

Stagsted, L. V., Nielsen, K., Daugaard, I. & Hansen, T. B. (2019). Noncoding AUG circRNAs constitute an abundant and conserved subclass of circles. Life Science Alliance, 2(3), Article e201900398. https://doi.org/10.26508/lsa.201900398

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Lisbeth Heilesen

Department of Molecular Biology and Genetics

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