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Department of Molecular Biology and Genetics

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Latest peer-reviewed publications at MBG

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Displaying results 2951 to 62 out of 62

Peer-reviewed publications at MBG - all years

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Aamann, M. D., Hvitby, C. P., Popuri, V., Muftuoglu, M., Lemminger, L. P. B., K. Skeby , C., Keijzers, G., Ahn, B., Bjørås , M., Bohr, V. & Stevnsner, T. V. (2014). Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity. Mechanisms of Ageing and Development, 135, 1-14. https://doi.org/10.1016/j.mad.2013.12.008

Poulsen, R. H., Rasmussen, J. T., Bøtker, H. E., Wæhrens, L. N., Falborg, L., Heegaard, C. W. & Rehling, M. (2014). Imaging the myocardium at risk with (99m)Tc-lactadherin administered after reperfusion in a porcine model. Nuclear Medicine and Biology, 41(1), 114-119. https://doi.org/10.1016/j.nucmedbio.2013.09.004

Christensen, B. S. & Sørensen, E. S. (2014). Osteopontin is highly susceptible to cleavage in bovine milk and the proteolytic fragments bind the αVβ3-integrin receptor. Journal of Dairy Science, 97(1), 136-146. https://doi.org/10.3168/jds.2013-7223

Perfeito, L., Sousa, A., Bataillon, T. & Gordo, I. (2014). Rates of fitness decline and rebound suggest pervasive epistasis. Evolution, 68(1), 150-162. https://doi.org/10.1111/evo.12234

Zhao, B., Xu, P., Jiang, L., Paaske, B., Kromann-Hansen, T., Jensen, J. K., Sørensen, H. P., Liu, Z., Nielsen, J. T., Christensen, A., Hosseini, M., Sørensen, K. K., Nielsen, N. C., Jensen, K. J., Huang, M. & Andreasen, P. A. (2014). A cyclic peptidic serine protease inhibitor: increasing affinity by increasing Peptide flexibility. PLoS One, 9(12), Article e115872. https://doi.org/10.1371/journal.pone.0115872

Munch, K., Mailund, T., Dutheil, J. Y. & Schierup, M. H. (2014). A fine-scale recombination map of the human-chimpanzee ancestor reveals faster change in humans than in chimpanzees and a strong impact of GC-biased gene conversion. Genome Research. https://doi.org/10.1101/gr.158469.113

Rattan, S. (2014). Aging is not a disease: implications for intervention. Aging and Disease, 5(3), 196-202. https://doi.org/10.14336/AD.2014.0500196

Fedosov, S. N., Fernandes, N. A. & Yusoff, M. F. B. M. (2014). Analysis of oil-biodiesel samples by high performance liquid chromatography using the normal phase column of new generation and the evaporative light scattering detector. Journal of Chromatography A, 1326, 56-62. https://doi.org/10.1016/j.chroma.2013.12.043

Giedyk, M., Fedosov, S. & Gryko, D. (2014). An amphiphilic, catalytically active, vitamin B12 derivative. Chemical Communications, 50(36). https://doi.org/10.1039/c4cc01064g

Sørensen, H. J., Foldager, L., Røge, R., Pristed, S. G., Andreasen, J. T. & Nielsen, J. (2014). An association between autumn birth and clozapine treatment in patients with schizophrenia: A population-based analysis. Nordic Journal of Psychiatry, 68(6), 428-432. https://doi.org/10.3109/08039488.2013.854408

Yang, C., Nilsson, L., Cheema, M. U., Wang, Y., Frøkiær, J., Gao, S., Kjems, J. & Nørregaard, R. (2014). Chitosan/siRNA Nanoparticles Targeting Cyclooxygenase Type 2 Attenuate Unilateral Ureteral Obstruction-induced Kidney Injury in Mice. Theranostics, 5(2), 110-123. https://doi.org/10.7150/thno.9717

Andersson, M., Mattle, D., Sitsel, O., Klymchuk, T., Nielsen, A. M., Møller, L. B., White, S. H., Nissen, P. & Gourdon, P. (2014). Copper-transporting P-type ATPases use a unique ion-release pathway. Nature Structural and Molecular Biology, 21, 43-48. https://doi.org/10.1038/nsmb.2721

Roy, A., Tesauro, C., Frøhlich, R., Hede, M. S., Nielsen, M. J., Kjeldsen, E., Bonven, B., Stougaard, M., Gromova, I. & Knudsen, B. R. (2014). Decreased camptothecin sensitivity of the stem-cell-like fraction of caco2 cells correlates with an altered phosphorylation pattern of topoisomerase I. PLoS One, 9(6), Article e99628. https://doi.org/10.1371/journal.pone.0099628

Cai, Z., Liu, H., He, Q., Pu, M., Lai, J., Li, X. & Jin, W. (2014). Differential genome evolution and speciation of Coix lacryma-jobi L. and Coix aquatica Roxb. hybrid guangxi revealed by repetitive sequence analysis and fine karyotyping. BMC Genomics, 15, 1025. https://doi.org/10.1186/1471-2164-15-1025

Demirovic, D., de Toda, I. M., Nizard, C. & Rattan, S. (2014). Differential translocation of heat shock factor-1 after mild and severe stress to human skin fibroblasts undergoing aging in vitro. Journal of Cell Communication and Signaling, 8(4), 333-339. https://doi.org/10.1007/s12079-014-0244-8

Cheema, M. U., Damkier, H. H., Nielsen, J., Poulsen, E. T., Enghild, J. J., Fenton, R. A. & Praetorius, J. (2014). Distal Renal Tubules Are Deficient in Aggresome Formation and Autophagy upon Aldosterone Administration. PLoS One, 9(7), e101258. https://doi.org/10.1371/journal.pone.0101258

Lopes, P., Dyrnesli, H., Lorenzen, N., Otzen, D. & Ferapontova, E. (2014). Electrochemical Analysis of the Fibrillation of Parkinson's Disease α-synuclein. Analyst, 139(4), 749-756. https://doi.org/10.1039/C3AN01616A

Eickhardt, E. A., Als, T. D., Mattheisen, M., Nyegaard, M., Demontis, D., Grove, J., Andorsdottir, G., Biskopstø, M., Wang, A., Mors, O., Bolund, L., Wang, J., Børglum, A. & Lescai, F. (2014). Enrichment Analysis of Genomic features to Identify Genome-Wide Patterns of Insertions/Deletions in Cases of Psychiatric Disorders from the Faroe Islands. Poster session presented at XXII World Congress of Psychiatric Genetics, København, Danmark, Denmark.

Jørgensen, P. & Rattan, S. (2014). Extracellular Matrix Modulates Morphology, Growth, Oxidative Stress Response and Functionality of Human Skin Fibroblasts during Aging In Vitro. Journal of Aging Science, 2(2). https://doi.org/10.4172/2329-8847.1000122

Ottaviani, A., Tesauro, C., Fjelstrup, S., Hougaard, R. F., Fiorani, P., Desideri, A. & Knudsen, B. R. (2014). Extraction of active enzymes from “hard-to-break-cells”: Evaluation by a RCA-based assay. https://doi.org/10.1109/ICSENS.2014.6985363

Okholm, A., Kjems, J. & Astakhova, K. (2014). Fluorescence detection of natural RNA using rationally designed "clickable" oligonucleotide probes. RSC Advances, 4(86), 45653-45656. https://doi.org/10.1039/c4ra07165d

Tomasiak, T. M., Pedersen, B. P., Chaudhary, S., Rodriguez, A., Colmanares, Y. R., Roe-Zurz, Z., Thamminana, S., Tessema, M. & Stroud, R. M. (2014). General qPCR and Plate Reader Methods for Rapid Optimization of Membrane Protein Purification and Crystallization Using Thermostability Assays. Current Protocols in Protein Science, 77, 29.11.1-29.11.14. https://doi.org/10.1002/0471140864.ps2911s77

Islam, M. S., Studer, B., Møller, I. M. & Asp, T. (2014). Genetics and biology of cytoplasmic male sterility and its applications for forage and turf grass breeding. Plant Breeding, 133(3), 299-312. https://doi.org/10.1111/pbr.12155

Do, D. N., Strathe, A. B., Ostersen, T., Pant, S. D. & Kadarmideen, H. N. (2014). Genome-wide association and pathway analysis of feed efficiency in pigs reveal candidate genes and pathways for residual feed intake. Frontiers in Genetics, 5(AUG), Article Article 307. https://doi.org/10.3389/fgene.2014.00307

Ngoc Do, D., Ostersen, T., Strathe, A. B., Mark, T., Jensen, J. & Kadarmideen, H. N. (2014). Genome-wide association and systems genetic analyses of residual feed intake, daily feed consumption, backfat and weight gain in pigs. BMC Genetics, 15, Article 27. https://doi.org/10.1186/1471-2156-15-27

Horton, M. W., Bodenhausen, N., Beilsmith, K., Meng, D., Muegge, B. D., Subramanian, S., Vetter, M. M., Vilhjálmsson, B. J., Nordborg, M., Gordon, J. I. & Bergelson, J. (2014). Genome-wide association study of Arabidopsis thaliana leaf microbial community. Nature Communications, 5, 5320. https://doi.org/10.1038/ncomms6320

Pedersen, J. S., Valen, E., Velazquez, A. M. V., Parker, B. J., Rasmussen, M., Lindgreen, S., Lilje, B., Tobin, D. J., Kelly, T. K., Vang, S., Andersson, R., Jones, P. A., Hoover, C. A., Tikhonov, A., Prokhortchouk, E., Rubin, E. M., Sandelin, A. G., Gilbert, M. T. P., Krogh, A. ... Orlando, L. A. A. (2014). Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome. Genome Research, 24, 454-466. https://doi.org/10.1101/gr.163592.113

Pujolar, J. M., Jacobsen, L. M. W., Als, T. D., Frydenberg, J., Munch, K., Jonsson, B., Jian, J. B., Cheng, L., Maes, G. E., Bernatchez, L. & Hansen, M. M. (2014). Genome-wide single generation signatures of local selection in the panmictic European eel. Molecular Ecology, 23, 2514-2528. https://doi.org/10.1111/mec.12753

Børglum, A. D., Demontis, D., Grove, J., Pallesen, J., Hollegaard, M. V., Pedersen, C. B., Hedemand, A., Mattheisen, M., Uitterlinden, A., Nyegaard, M., Orntoft, T., Wiuf, C., Didriksen, M., Nordentoft, M., Nöthen, M. M., Rietschel, M., Ophoff, R. A., Cichon, S., Yolken, R. H. ... GROUP Investigators (2014). Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci. Molecular Psychiatry, Mar;19(3), 325-33. https://doi.org/10.1038/mp.2013.2

Rattan, S. (2014). Guest Editorial. Prime, 4. http://content.yudu.com/A2zatm/PrimeJul2014/resources/1.htm

Le Bourg, E. & Rattan, S. (2014). Hormesis and trade-offs: A comment. Dose-Response, 12(4), 522-524. https://doi.org/10.2203/dose-response.14-054.Le_Bourg, https://doi.org/10.2203/dose-response.14-054.LeBourg

Iversen, O. S., Thomsen, B. S. & Elbæk, L. (2014). IDC 2014 chairs' welcome. -, iii.

Yusoff, M. F. B. M., Guo, Z. & Fedosov, S. (2014). Kinetic analysis of esterification using liquid lipase. In 105th AOCS Annual Meeting and Expo, Abstracts AOCS Press. http://www.aocs.org/Meetings/content.cfm?ItemNumber=40455

Li, W., Fedosov, S., Tan, T., Xu, X. & Guo, Z. (2014). Kinetic Insights of DNA/RNA Segment Salts Catalyzed Knoevenagel Condensation Reaction. A C S Catalysis, 4(9), 3294–3300. https://doi.org/10.1021/cs500882r

Yusoff, M. F. B. M., Fedosov, S. & Guo, Z. (2014). Kinetic Model of Biodiesel Production using Liquid Lipase Callera Trans L. (TLL). In 12th Euro Fed Lipid Congress Book of Abstracts: Oils, Fats and Lipids: From Lipidomics to Industrial Innovation https://gdch.enterprise-ems.de/tms/frontend/index.cfm?l=4569&id=0&dat_h=&sp_id=2&modus=

Liu, W., Kavaliauskas, D., Schrader, J., Poruri, K., Birkedal, V., Goldman, E., Jakubowski, H., Mandecki, W., Uhlenbeck, O., Knudsen, C. R., Goldman, Y. & Cooperman, B. (2014). Labeled EF-Tus for rapid kinetic studies of pretranslocation complex formation. A C S Chemical Biology, 9(10), 2421-2431.

Jørgensen, P., Milkovic, L., Zarkovic, N., Waeg, G. & Rattan, S. I. S. (2014). Lipid peroxidation-derived 4-hydroxynonenal-modified proteins accumulate in human facial skin fibroblasts during ageing in vitro. Biogerontology, 15(1), 105-110. https://doi.org/10.1007/s10522-013-9482-z

Aschard, H., Vilhjálmsson, B. J., Greliche, N., Morange, P.-E., Trégouët, D.-A. & Kraft, P. (2014). Maximizing the power of principal-component analysis of correlated phenotypes in genome-wide association studies. American Journal of Human Genetics, 94(5), 662-76. https://doi.org/10.1016/j.ajhg.2014.03.016

Gao, S., Hein, S., Dagnæs-Hansen, F., Weyer, K., Yang, C., Nielsen, R., Christensen, E. I., Fenton, R. A. & Kjems, J. (2014). Megalin-Mediated Specific Uptake of Chitosan/siRNA Nanoparticles in Mouse Kidney Proximal Tubule Epithelial Cells Enables AQP1 Gene Silencing. Theranostics, 4(10), 1039-51. https://doi.org/10.7150/thno.7866

Pham, L. D., Do, D. N., Nam, L. Q., van Ba, N., Minh, L. T. A., Hoan, T. X., Cuong, V. C. & Kadarmideen, H. N. (2014). Molecular genetic diversity and genetic structure of Vietnamese indigenous pig populations. Journal of Animal Breeding and Genetics, 131(5), 379-386. https://doi.org/10.1111/jbg.12068

Rattan, S. (2014). Molecular gerontology: from homeodynamics to hormesis. Current Pharmaceutical Design, 20(18), 3036-3039. https://doi.org/10.2174/13816128113196660708

Buttenschøn, H. N., Foldager, L., Elfving, B., Poulsen, P. H. P., Uher, R. & Mors, O. (2014). Neurotrophic factors in depression in response to treatment.

Andersson, R., Andersen, P. R., Valen, E., Core, L. J., Bornholdt, J., Boyd, M., Heick Jensen, T. & Sandelin, A. (2014). Nuclear stability and transcriptional directionality separate functionally distinct RNA species. Nature Communications, 5, 1-10. Article 5336. https://doi.org/10.1038/ncomms6336

Kjems, J., Ferapontova, E. & Gothelf, K. V. (Eds.) (2014). Nucleic Acid Nanotechnology. Springer. Nucleic Acids and Molecular Biology Vol. 29 https://doi.org/10.1007/978-3-642-38815-6

Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., Zang, C., Ripke, S., Bulik-Sullivan, B., Stahl, E., Kähler, A. K., Hultman, C. M., Purcell, S. M., McCarroll, S. A., Daly, M., Pasaniuc, B., Sullivan, P. F., Neale, B. M., Wray, N. R. ... Schizophrenia Working Group of the Psychiatric Genomics Consortium (Manuel Mattheisen and Jakob Grove, members) (2014). Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases. American Journal of Human Genetics, 95(5), 535-52. https://doi.org/10.1016/j.ajhg.2014.10.004

Ghodke, S. D., Jensen, G. V., Svane, A. S. P., Weise, K., Søndergaard, A., Behrens, M. A., Pedersen, J. S., Nielsen, N. C., Pedersen, J. S., Winter, R. & Otzen, D. (2014). Polymorphism, metastable species and interconversion: the many states of glucagon fibrils. In V. Uversky & Y. Lyubchenko (Eds.), Bio-nanoimaging: Protein misfolding and aggregation (pp. 373-386). Elsevier. https://doi.org/10.1016/B978-0-12-394431-3.00034-1

Als, T. D., Lescai, F., Dahl, H. A., Grove, J., Demontis, D., Wang, A. G., Andorsdottir, G., Biskopstø, M., Johansen, O., Nyegaard, M., Bolund, L., Mors, O., Wang, J. & Børglum, A. (2014). Population Structure & Cryptic Relatedness of the isolated Population of the Faroe Islands. Poster session presented at XXII World Congress of Psychiatric Genetics, København, Denmark.

Kjems, J., Ferapontova, E. & Gothelf, K. V. (2014). Preface. In J. Kjems, E. Ferapontova & K. V. Gothelf (Eds.), Nucleic Acid Nanotechnology (pp. ix-x). Springer.

Bek-Thomsen, M., Lomholt, H. B., Scavenius, C., Enghild, J. J. & Brüggemann, H. (2014). Proteome Analysis of Human Sebaceous Follicle Infundibula Extracted from Healthy and Acne-Affected Skin. PLoS One, 9(9), e107908. https://doi.org/10.1371/journal.pone.0107908

Wang, W.-Q., Ye, J.-Q., Rogowska-Wrzesinska, A., Wojdyla, K. I., Jensen, O. N., Møller, I. M. & Song, S.-Q. (2014). Proteomic Comparison between Maturation Drying and Prematurely Imposed Drying of Zea mays Seeds Reveals a Potential Role of Maturation Drying in Preparing Proteins for Seed Germination, Seedling Vigor, and Pathogen Resistance. Journal of Proteome Research, 13(2), 606-626. https://doi.org/10.1021/pr4007574

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Lisbeth Heilesen