Franceschini, S., Grelet, C., Leblois, J., Gengler, N., Soyeurt, H. & GplusE Consortium (2022).
Can unsupervised learning methods applied to milk recording big data provide new insights into dairy cow health? Journal of Dairy Science,
105(8), 6760-6772.
https://doi.org/10.3168/jds.2022-21975
Sokac, M., Ahrenfeldt, J., Litchfield, K., Watkins, T. B. K.
, Knudsen, M., Dyrskjøt, L., Jakobsen, M. R. & Birkbak, N. J. (2022).
Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer.
Cancer Research Communications,
2(8), 762-771.
https://doi.org/10.1158/2767-9764.CRC-22-0047,
https://doi.org/10.1158/2767-9764.CRC-22-0047
Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Artigas, M. S., Bybjerg-Grauholm, J., Bækvad-Hansen, M.
, Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T.
, Mors, O., Hougaard, D. M.
, Mortensen, P. B. ... Demontis, D. (2022).
Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder.
Nature Genetics,
54(8), 1117-1124.
https://doi.org/10.1038/s41588-022-01143-7
Fields, B., Moffat, E. K., Harrison, E.
, Andersen, S. U., Young, J. P. W. & Friman, V.-P. (2022).
Genetic variation is associated with differences in facilitative and competitive interactions in the Rhizobium leguminosarum species complex.
Environmental Microbiology,
24(8), 3463-3485.
https://doi.org/10.1111/1462-2920.15720
Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., Li, Z., Shiloh, Y., Opresko, P. L., Egly, J. M., Kirkwood, T., Verdin, E., Bohr, V. A., Cox, L. S.
, Stevnsner, T. ... Fang, E. F. (2022).
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary.
Aging,
14(16), 6829-6839.
https://doi.org/10.18632/aging.204248
Coutant, M. P., Malmkvist, J., Kaiser, M., Foldager, L. & Herskin, M. S. (2022).
On-farm administration of local anaesthetic and surgical castration of piglets: acute behavioural and physiological consequences. In M. Kjosevski, S. Waiblinger & V. Ilieski (Eds.),
Proceedings of the 55th Congress of the ISAE: Animal Behaviour and Beyond (pp. 19-19).
https://www.applied-ethology.org/res/ISAE_2022_PROCEEDINGS_e-version.pdf
Coutant, M. P., Malmkvist, J., Kaiser, M. Ø., Foldager, L. & Herskin, M. S. (2022).
Piglets' acute responses to procaine-based local anesthetic injection and surgical castration: Effects of two volumes of anesthetic.
Frontiers in Pain Research,
3, Article 943138.
https://doi.org/10.3389/fpain.2022.943138
Antaki, D., Guevara, J., Maihofer, A. X., Klein, M., Gujral, M.
, Grove, J., Carey, C. E., Hong, O., Arranz, M. J., Hervas, A., Corsello, C., Vaux, K. K., Muotri, A. R., Iakoucheva, L. M., Courchesne, E., Pierce, K., Gleeson, J. G., Robinson, E. B., Nievergelt, C. M. & Sebat, J. (2022).
Publisher Correction: A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex.
Nature Genetics,
54(8), Article 1259.
https://doi.org/10.1038/s41588-022-01145-5
Henriksen, M. L., Nielsen, C.
, Pedersen, D., Andersen, G. R., Thiel, S., Palarasah, Y. & Hansen, S. W. K. (2022).
Quantification of the pro-form of human complement component factor D (adipsin).
Journal of Immunological Methods,
507, Article 113295.
https://doi.org/10.1016/j.jim.2022.113295
Jensen, R. K., Pedersen, H., Lorentzen, J., Laursen, N. S., Vorup-Jensen, T. & Andersen, G. R. (2022).
Structural insights into the function-modulating effects of nanobody binding to the integrin receptor αMβ2.
Journal of Biological Chemistry,
298(8), Article 102168.
https://doi.org/10.1016/j.jbc.2022.102168
Harwood, S. L., Diep, K., Nielsen, N. S., Jensen, K. T. & Enghild, J. J. (2022).
The conformational change of the protease inhibitor α2-macroglobulin is triggered by the retraction of the cleaved bait region from a central channel.
Journal of Biological Chemistry,
298(8), Article 102230.
https://doi.org/10.1016/j.jbc.2022.102230
Møhlenberg, M., Eriksen, P. L., Laursen, T. L., Nielsen, M. B., Hamilton-Dutoit, S. J., Grønbæk, H., Hartmann, R. & Thomsen, K. L. (2022).
The presence of interferon affects the progression of non-alcoholic fatty liver disease.
Genes and Immunity,
23(5), 157–165.
https://doi.org/10.1038/s41435-022-00176-6
Greve, A. N., Jepsen, J. R. M., Mortensen, E. L., Uher, R., Mackenzie, L.
, Foldager, L., Gantriis, D., Burton, B. K., Ellersgaard, D., Christiani, C. J., Spang, K. S., Hemager, N., Uddin, J., Henriksen, M. T.
, Zahle, K. K., Stadsgaard, H., Plessen, K. J., Thorup, A. A. E., Nordentoft, M.
... Bliksted, V. (2022).
Transmission of intelligence, working memory, and processing speed from parents to their seven-year-old offspring is function specific in families with schizophrenia or bipolar disorder.
Schizophrenia Research,
246, 195-201.
https://doi.org/10.1016/j.schres.2022.06.032
Christensen, D. S., Ahrenfeldt, J., Sokač, M., Kisistók, J., Thomsen, M. K., Maretty, L., McGranahan, N.
& Birkbak, N. J. (2022).
Treatment Represents a Key Driver of Metastatic Cancer Evolution.
Cancer Research,
82(16), 2918-2927.
https://doi.org/10.1158/0008-5472.CAN-22-0562
Meisl, G., Xu, C. K., Taylor, J. D., Michaels, T. C. T., Levin, A.
, Otzen, D., Klenerman, D., Matthews, S., Linse, S.
, Andreasen, M. & Knowles, T. P. J. (2022).
Uncovering the universality of self-replication in protein aggregation and its link to disease.
Science Advances,
8(32), Article eabn6831.
https://doi.org/10.1126/sciadv.abn6831
Kobek-Kjeldager, C., Jensen, L. D., Foldager, L., Kaiser, M., Thodberg, K. & Herskin, M. S. (2022).
Validation of behavioural sampling techniques for 20-25 kg pigs during 23-hour transport. In M. Kjosevski, S. Waiblinger & V. Ilieski (Eds.),
Proceedings of the 55th Congress of the ISAE: Animal Behaviour and Beyond (pp. 167-167).
https://www.applied-ethology.org/res/ISAE_2022_PROCEEDINGS_e-version.pdf
Neumann, C., Focht, D., Trampari, S., Lyons, J. A. & Nissen, P. (2022).
Variations on a theme: Crystal forms of the amino-acid transporter MhsT.
Acta Crystallographica Section F: Structural Biology Communications,
78(Part 8), 297-305.
https://doi.org/10.1107/S2053230X22007154
Gerlach, P.
, Garland, W., Lingaraju, M., Salerno-Kochan, A., Bonneau, F., Basquin, J.
, Jensen, T. H. & Conti, E. (2022).
Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Molecular Cell,
82(13), 2505-2518.e7.
https://doi.org/10.1016/j.molcel.2022.04.011
Rowe, T. B., Stafford, T. W., Fisher, D. C.
, Enghild, J. J., Quigg, J. M., Ketcham, R. A., Sagebiel, J. C., Hanna, R. & Colbert, M. W. (2022).
Human Occupation of the North American Colorado Plateau ∼37,000 Years Ago.
Frontiers in Ecology and Evolution,
10, Article 903795.
https://doi.org/10.3389/fevo.2022.903795
Jepsen, M. R., Østergaard, J. A., Conover, C. A.
, Wogensen, L., Birn, H., Krag, S. P., Fenton, R. A. & Oxvig, C. (2022).
Increased activity of the metalloproteinase PAPP-A promotes diabetes-induced glomerular hypertrophy.
Metabolism: Clinical and Experimental,
132, Article 155218.
https://doi.org/10.1016/j.metabol.2022.155218
Pedersen, J. G., Sokac, M., Sørensen, B. S., Luczak, A. A.
, Aggerholm-Pedersen, N., Birkbak, N. J., Øllegaard, T. H. & Jakobsen, M. R. (2022).
Increased Soluble PD-1 Predicts Response to Nivolumab plus Ipilimumab in Melanoma.
Cancers,
14(14), Article 3342.
https://doi.org/10.3390/cancers14143342
Sadik, A., Dardani, C., Pagoni, P., Havdahl, A., Stergiakouli, E., Khandaker, G. M., Sullivan, S. A., Zammit, S., Jones, H. J., Davey Smith, G., Dalman, C., Karlsson, H., Gardner, R. M., Rai, D. & The iPSYCH Autism Spectrum Disorder Working Group (2022).
Parental inflammatory bowel disease and autism in children.
Nature Medicine,
28(7), 1406-1411.
https://doi.org/10.1038/s41591-022-01845-9
Sahin, C., Østerlund, E. C., Österlund, N., Costeira-Paulo, J.
, Pedersen, J. N., Christiansen, G.
, Nielsen, J., Grønnemose, A. L., Amstrup, S. K., Tiwari, M. K., Rao, R. S. P., Bjerrum, M. J., Ilag, L. L., Davies, M. J., Marklund, E. G.
, Pedersen, J. S., Landreh, M.
, Møller, I. M., Jørgensen, T. J. D.
& Otzen, D. E. (2022).
Structural Basis for Dityrosine-Mediated Inhibition of α-Synuclein Fibrillization.
Journal of the American Chemical Society,
144(27), 11949-11954.
https://doi.org/10.1021/jacs.2c03607
Bisiak, F., Chrenková, A., Zhang, S. D.
, Pedersen, J. N., Otzen, D. E., Zhang, Y. E.
& Brodersen, D. E. (2022).
Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response.
Journal of Biological Chemistry,
298(7), Article 102142.
https://doi.org/10.1016/j.jbc.2022.102142
Pedersen, H., Jensen, R. K., Hansen, A. G., Petersen, S. V., Thiel, S., Laursen, N. S. & Andersen, G. R. (2022).
Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity.
Frontiers in Immunology,
13, Article 872536.
https://doi.org/10.3389/fimmu.2022.872536
Khateb, H., Sørensen, R. S., Cramer, K., Eklund, A. S.
, Kjems, J., Meyer, R. L., Jungmann, R.
& Sutherland, D. S. (2022).
The Role of Nanoscale Distribution of Fibronectin in the Adhesion of Staphylococcus aureus Studied by Protein Patterning and DNA-PAINT.
ACS Nano,
16(7), 10392-10403.
https://doi.org/10.1021/acsnano.2c00630
Renaud, G., Nørgaard, M., Lindberg, J., Grönberg, H., De Laere, B.
, Jensen, J. B., Borre, M., Andersen, C. L., Sørensen, K. D., Maretty, L. & Besenbacher, S. (2022).
Unsupervised detection of fragment length signatures of circulating tumor DNA using non-negative matrix factorization.
eLife,
11, Article e71569.
https://doi.org/10.7554/ELIFE.71569
Hartmann, S.
, Ling, M., Dreyer, L. S. A., Zipori, A.
, Finster, K., Grawe, S.
, Jensen, L. Z., Borck, S., Reicher, N., Niedermeier, D.
, Jones, N. C., Hoffmann, S. V., Wex, H., Rudich, Y.
, Boesen, T. & Santl-Temkiv, T. (2022).
Structure and Protein-Protein Interactions of Ice Nucleation Proteins Drive Their Activity.
Frontiers in Microbiology,
13, Article 872306.
https://doi.org/10.3389/fmicb.2022.872306
Wu, Y., Biswas, D., Usaite, I., Angelova, M., Boeing, S., Karasaki, T., Veeriah, S., Czyzewska-Khan, J., Morton, C., Joseph, M., Hessey, S., Reading, J., Georgiou, A., Al-Bakir, M. & TRACERx Consortium (2022).
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Nature Cancer,
3(6), 696-709.
https://doi.org/10.1038/s43018-022-00376-z
Dijkman, R., Verma, A. K., Selvaraj, M., Ghimire, R.
, Gad, H. H., Hartmann, R., More, S., Perlman, S., Thiel, V. & Channappanavar, R. (2022).
Effective Interferon Lambda Treatment Regimen To Control Lethal MERS-CoV Infection in Mice.
Journal of Virology,
96(11), Article e00364-22.
https://doi.org/10.1128/jvi.00364-22
Märcher, A., Kumar, V., Andersen, V. L., El-Chami, K., Nguyen, T. J. D., Skaanning, M. K., Rudnik-Jansen, I., Nielsen, J. S., Howard, K. A., Kjems, J. & Gothelf, K. V. (2022).
Functionalized Acyclic (l)-Threoninol Nucleic Acid Four-Way Junction with High Stability In Vitro and In Vivo.
Angewandte Chemie - International Edition,
61(24), Article 202115275.
https://doi.org/10.1002/anie.202115275
Duncan, C. J. A.
, Skouboe, M. K., Howarth, S.
, Hollensen, A. K., Chen, R., Børresen, M. L., Thompson, B. J., Stremenova Spegarova, J., Hatton, C. F., Stæger, F. F., Andersen, M. K., Whittaker, J.
, Paludan, S. R., Jørgensen, S. E., Thomsen, M. K., Mikkelsen, J. G., Heilmann, C., Buhas, D., Øbro, N. F.
... Mogensen, T. H. (2022).
Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic.
The Journal of Experimental Medicine,
219(6), Article e20212427.
https://doi.org/10.1084/jem.20212427
Wigdor, E. M., Weiner, D. J.
, Grove, J., Fu, J. M.
, Thompson, W. K., Carey, C. E., Baya, N., van der Merwe, C., Walters, R. K., Satterstrom, F. K., Palmer, D. S., Rosengren, A., Bybjerg-Grauholm, J., Hougaard, D. M.
, Mortensen, P. B., Daly, M. J., Talkowski, M. E., Sanders, S. J., Bishop, S. L. ... iPSYCH Consortium (2022).
The female protective effect against autism spectrum disorder.
Cell Genomics,
2(6), Article 100134.
https://doi.org/10.1016/j.xgen.2022.100134
Mogensen, E. H., Poulsen, E. T., Thøgersen, I. B., Yamamoto, K.
, Brüel, A. & Enghild, J. J. (2022).
The low-density lipoprotein receptor-related protein 1 (LRP1) interactome in the human cornea.
Experimental Eye Research,
219, Article 109081.
https://doi.org/10.1016/j.exer.2022.109081
Keller, J. G., Hymøller, K. M., Thorsager, M. E., Hansen, N. Y., Erlandsen, J. U., Tesauro, C., Simonsen, A. K. W., Andersen, A. B., Vandsø Petersen, K., Holm, L. L.
, Stougaard, M., Andresen, B. S., Kristensen, P.
, Frøhlich, R. & Knudsen, B. R. (2022).
Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation.
Nucleic Acids Research,
50(11), 6332-6342.
https://doi.org/10.1093/nar/gkac482
Schröder, S. K., Schüler, H. M.
, Petersen, K. V., Tesauro, C., Knudsen, B. R., Pedersen, F. S., Krus, F., Buhl, E. M., Roeb, E., Roderfeld, M., Borojevic, R., Almeida, J. L. & Weiskirchen, R. (2022).
Genetic and Molecular Characterization of the Immortalized Murine Hepatic Stellate Cell Line GRX.
Cells,
11(9), Article 1504.
https://doi.org/10.3390/cells11091504
Farzadfard, A., König, A.
, Petersen, S. V., Nielsen, J., Vasili, E., Dominguez-Meijide, A., Buell, A. K., Outeiro, T. F.
& Otzen, D. E. (2022).
Glycation modulates alpha-synuclein fibrillization kinetics: a sweet spot for inhibition.
The Journal of Biological Chemistry,
298(5), Article 101848.
https://doi.org/10.1016/j.jbc.2022.101848
Peña-Díaz, S., Pujols, J., Vasili, E.
, Pinheiro, F., Santos, J., Manglano-Artuñedo, Z., Outeiro, T. F. & Ventura, S. (2022).
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains.
Journal of Biological Chemistry,
298(5), Article 101902.
https://doi.org/10.1016/j.jbc.2022.101902