Árnadóttir, S. S., Mattesen, T. B., Vang, S., Madsen, M. R., Madsen, A. H., Birkbak, N. J., Bramsen, J. B. & Andersen, C. L. (2020).
Transcriptomic and proteomic intra-tumor heterogeneity of colorectal cancer varies depending on tumor location within the colorectum.
PLoS One,
15(12), Article e0241148.
https://doi.org/10.1371/journal.pone.0241148
Martins, P. M., Navarro, S., Silva, A., Pinto, M. F., Sárkány, Z., Figueiredo, F., Pereira, P. J. B., Pinheiro, F., Bednarikova, Z., Burdukiewicz, M., Galzitskaya, O. V., Gazova, Z., Gomes, C. M., Pastore, A., Serpell, L. C., Skrabana, R., Smirnovas, V., Ziaunys, M.
, Otzen, D. E. ... Macedo-Ribeiro, S. (2020).
MIRRAGGE - Minimum Information Required for Reproducible AGGregation Experiments.
Frontiers in Molecular Neuroscience,
13, Article 582488.
https://doi.org/10.3389/fnmol.2020.582488Holt-Danborg, L., Skovbjerg, S., Goderum, K. W., Nonboe, A. W., Stankevic, E.
, Frost, Á. K., Vitved, L.
, Jensen, J. K. & Vogel, L. K. (2020).
Insights into the regulation of the matriptase-prostasin proteolytic system.
Biochemical Journal,
477(22), 4349-4365.
https://doi.org/10.1042/BCJ20200630Moesgaard, L., Petersen, D., Szomek, M., Reinholdt, P.
, Winkler, M., Frain, K. M., Müller, P.
, Pedersen, B. P., Kongsted, J. & Wüstner, D. (2020).
Mechanistic Insight into Lipid Binding to Yeast Niemann Pick Type C2 Protein.
Biochemistry,
59(45), 4407–4420.
https://doi.org/10.1021/acs.biochem.0c00574Wong, E. S., Zheng, D., Tan, S. Z., Bower, N. I., Garside, V.
, Vanwalleghem, G., Gaiti, F., Scott, E., Hogan, B. M., Kikuchi, K., McGlinn, E., Francois, M. & Degnan, B. M. (2020).
Deep conservation of the enhancer regulatory code in animals.
Science,
370(6517), Article eaax8137.
https://doi.org/10.1126/science.aax8137Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M.
, McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, M.
, Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, T.
, Svenning, J.-C. & Horsdal, H. T. (2020).
Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia.
Schizophrenia Bulletin,
46(6), 1629-1637.
https://doi.org/10.1093/schbul/sbaa058
Dai, L., Hallmark, L.
, Bofill De Ros, X., Crouch, H., Chen, S., Shi, T., Yang, A., Lian, C., Zhao, Y., Tran, B. & Gu, S. (2020).
Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells.
RNA Biology,
17(11), 1603-1612.
https://doi.org/10.1080/15476286.2020.1813439Stoll, L., Rodríguez-Trejo, A., Guay, C., Brozzi, F., Bayazit, M. B., Gattesco, S., Menoud, V., Sobel, J., Marques, A. C.
, Venø, M. T., Esguerra, J. L. S., Barghouth, M., Suleiman, M., Marselli, L.
, Kjems, J., Eliasson, L., Renström, E., Bouzakri, K., Pinget, M. ... Regazzi, R. (2020).
A circular RNA generated from an intron of the insulin gene controls insulin secretion.
Nature Communications,
11, Article 5611.
https://doi.org/10.1038/s41467-020-19381-wZhang, B.
, Nandakumar, R., Reinert, L. S., Huang, J., Laustsen, A., Gao, Z., Sun, C.
, Jensen, S. B., Troldborg, A., Assil, S., Berthelsen, M. F., Scavenius, C., Zhang, Y., Windross, S. J., Olagnier, D., Prabakaran, T., Bodda, C.
, Narita, R., Cai, Y. ... Paludan, S. R. (2020).
Author Correction: STEEP mediates STING ER exit and activation of signaling (Nature Immunology, (2020), 21, 8, (868-879), 10.1038/s41590-020-0730-5).
Nature Immunology,
21(11), 1468-1469.
https://doi.org/10.1038/s41590-020-0803-5Dalskov, L., Narita, R., Andersen, L. L., Jensen, N., Assil, S., Kristensen, K. H., Mikkelsen, J. G., Fujita, T.
, Mogensen, T. H., Paludan, S. R. & Hartmann, R. (2020).
Characterization of distinct molecular interactions responsible for IRF3 and IRF7 phosphorylation and subsequent dimerization.
Nucleic Acids Research,
48(20), 11421-11433.
https://doi.org/10.1093/nar/gkaa873
Conrad, T., Ntini, E., Lang, B., Cozzuto, L., Andersen, J. B., Marquardt, J. U., Ponomarenko, J., Tartaglia, G. G.
& Ørom, U. A. V. (2020).
Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing.
RNA,
26(11), 1726-1730.
https://doi.org/10.1261/rna.076240.120Aminzadeh, A., Tiwari, M. K., Mamah Mustapha, S. S., Navarrete, S. J., Henriksen, A. B.
, Møller, I. M., Krogfelt, K. A., Bjerrum, M. J. & Jørgensen, R. (2020).
Detoxification of toxin A and toxin B by copper ion-catalyzed oxidation in production of a toxoid-based vaccine against Clostridioides difficile.
Free Radical Biology and Medicine,
160, 433-446.
https://doi.org/10.1016/j.freeradbiomed.2020.08.021Peltonen, J., Tuomainen, K., Sallinen, T.
, Faress, I., Suleymanova, I., Al-Samadi, A., Salo, T. & Åström, P. (2020).
Effect of sex steroid hormones on tongue cancer cells in vitro.
Anticancer Research,
40(11), 6029-6037.
https://doi.org/10.21873/anticanres.14624Arora, D.
, Abel, N. B., Liu, C., van Damme, P., Yperman, K., Eeckhout, D., Vu, L. D.
, Wang, J., Tornkvist, A., Impens, F., Korbei, B., van Leene, J., Goossens, A., de Jaeger, G., Ott, T., Moschou, P. N. & van Damme, D. (2020).
Establishment of proximity-dependent biotinylation approaches in different plant model systems.
Plant Cell,
32(11), 3388-3407.
https://doi.org/10.1105/TPC.20.00235Adams, M. J., Howard, D. M., Luciano, M., Clarke, T.-K., Davies, G., Hill, W. D., Smith, D., Deary, I. J., Porteous, D. J., McIntosh, A. M., 23andMe Research Team & Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium (2020).
Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition.
Psychological Medicine,
50(15), 2526–2535.
https://doi.org/10.1017/S0033291719002629Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N.
, Kjems, J. ... LifeTime Community Working Groups (2020).
LifeTime and improving European healthcare through cell-based interceptive medicine.
Nature,
587, 377-386.
https://doi.org/10.1038/s41586-020-2715-9Gonçalves, N. P., Yan, Y., Ulrichsen, M., Venø, M. T., Poulsen, E. T., Enghild, J. J., Kjems, J. & Vægter, C. B. (2020).
Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin.
Biomedicines,
8(11), 1-24. Article 450.
https://doi.org/10.3390/biomedicines8110450
Watkins, T. B. K., Lim, E. L., Petkovic, M., Elizalde, S.
, Birkbak, N. J., Wilson, G. A., Moore, D. A., Grönroos, E., Rowan, A., Dewhurst, S. M., Demeulemeester, J., Dentro, S. C., Horswell, S., Au, L., Haase, K., Escudero, M., Rosenthal, R., Bakir, M. A., Xu, H. ... Swanton, C. (2020).
Pervasive chromosomal instability and karyotype order in tumour evolution.
Nature,
587, 126-132.
https://doi.org/10.1038/s41586-020-2698-6Lukassen, M. V., Poulsen, E. T., Donaghy, J.
, Mogensen, E. H., Christie, K. A., Roshanravan, H., DeDioniso, L., Nesbit, M. A., Moore, T.
& Enghild, J. J. (2020).
Protein Analysis of the TGFBIR124H Mouse Model Gives Insight into Phenotype Development of Granular Corneal Dystrophy.
Proteomics - Clinical Applications,
14(6), Article 1900072.
https://doi.org/10.1002/prca.201900072
Gokuldass, A., Draghi, A., Papp, K., Borch, T., Nielsen, M., Wulff Westergaard, M. C., Andersen, R., Schina, A., Bol, K. F., Chamberlain, C. A., Presti, M., Met, Ö., Harbst, K., Lauss, M.
, Soraggi, S., Csabai, I., Szallasi, Z., Jönsson, G., Svane, I. M. & Donia, M. (2020).
Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8+ T Cells in Non-Melanoma Cancers Compared to Melanoma.
Cancers,
12(11), 1-15. Article 3344.
https://doi.org/10.3390/cancers12113344Bodó, K.
, Hayashi, Y., Gerencsér, G., László, Z., Kéri, A., Galbács, G., Telek, E., Mészáros, M., Deli, M. A., Kokhanyuk, B., Németh, P. & Engelmann, P. (2020).
Species-specific sensitivity of Eisenia earthworms towards noble metal nanoparticles: a multiparametric in vitro study.
Environmental Science: Nano,
7(11), 3509-3525.
https://doi.org/10.1039/c9en01405eStevenson, A. J.
, Vanwalleghem, G., Stewart, T. A., Condon, N. D., Lloyd-Lewis, B., Marino, N., Putney, J. W., Scott, E. K., Ewing, A. D.
& Davis, F. M. (2020).
Multiscale imaging of basal cell dynamics in the functionally mature mammary gland.
Proceedings of the National Academy of Sciences (PNAS),
117(43), 26822-26832.
https://doi.org/10.1073/pnas.2016905117Peña-Díaz, S., Pujols, J.
, Pinheiro, F., Santos, J., Pallarés, I., Navarro, S., Conde-Gimenez, M., García, J., Salvatella, X., Dalfó, E., Sancho, J. & Ventura, S. (2020).
Inhibition of α-Synuclein Aggregation and Mature Fibril Disassembling With a Minimalistic Compound, ZPDm.
Frontiers in Bioengineering and Biotechnology,
8, Article 588947.
https://doi.org/10.3389/fbioe.2020.588947
Pedersen, H., Jensen, R. K., Jensen, J. M. B., Fox, R.
, Pedersen, D. V., Olesen, H. G., Hansen, A. G., Christiansen, D.
, Mazarakis, S. M. M., Lojek, N.
, Hansen, P., Gadeberg, T. A. F., Zarantonello, A., Laursen, N. S., Mollnes, T. E., Johnson, M. B., Stevens, B.
, Thiel, S. & Andersen, G. R. (2020).
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
Journal of Immunology,
205(8), 2287-2300.
https://doi.org/10.4049/jimmunol.2000752
Felgenhauer, U., Schoen, A.
, Gad, H. H., Hartmann, R., Schaubmar, A. R., Failing, K., Drosten, C. & Weber, F. (2020).
Inhibition of SARS-CoV-2 by type I and type III interferons.
The Journal of Biological Chemistry,
295(41), 13958-13964.
https://doi.org/10.1074/jbc.AC120.013788Eskandari, H., Ghanadian, M., Noleto-Dias, C., Lomax, C., Tawfike, A.
, Christiansen, G., Sutherland, D. S., Ward, J. L.
, Mohammad-Beigi, H. & Otzen, D. E. (2020).
Inhibitors of α-Synuclein fibrillation and oligomer toxicity in Rosa damascena: the all-pervading powers of flavonoids and phenolic glycosides.
ACS Chemical Neuroscience,
11(19), 3161–3173.
https://doi.org/10.1021/acschemneuro.0c00528
Plana-Ripoll, O., Musliner, K. L., Dalsgaard, S., Momen, N. C., Weye, N., Christensen, M. K., Agerbo, E., Iburg, K. M., Laursen, T. M., Mortensen, P. B., Pedersen, C. B., Petersen, L. V., Santomauro, D. F.
, Vilhjálmsson, B. J., Whiteford, H. A.
& McGrath, J. J. (2020).
Nature and prevalence of combinations of mental disorders and their association with excess mortality in a population-based cohort study.
World Psychiatry,
19(3), 339-349.
https://doi.org/10.1002/wps.20802
Jørgensen, S. E., Christiansen, M., Høst, C., Glerup, M., Mahler, B., Lausten, M. M., Gad, H. H., Hartmann, R., Herlin, T. & Mogensen, T. H. (2020).
Systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome due to a CASP1 variant causing inflammasome hyperactivation.
Rheumatology (Oxford, England),
59(10), 3099-3105.
https://doi.org/10.1093/rheumatology/keaa242
Rossnerova , A., Izzotti , A., Pulliero , A., Bast, A.
, Rattan, S. & Rossner , P. (2020).
The Molecular Mechanisms of Adaptive Response Related to Environmental Stress.
International Journal of Molecular Sciences ,
21(19), 1-15. Article 7053.
https://doi.org/10.3390/ijms21197053Dou, Y., Kalmykova, S., Pashkova, M., Oghbaie, M., Jiang, H., Molloy, K. R., Chait, B. T., Rout, M. P., Fenyö, D.
, Jensen, T. H., Altukhov, I. & LaCava, J. (2020).
Affinity proteomic dissection of the human nuclear cap-binding complex interactome.
Nucleic Acids Research,
48(18), 10456-10469.
https://doi.org/10.1093/nar/gkaa743
Hollensen, A. K., Thomsen, H. S., Lloret-Llinares, M., Kamstrup, A. B., Jensen, J. M., Luckmann, M., Birkmose, N., Palmfeldt, J., Jensen, T. H., Hansen, T. B. & Damgaard, C. K. (2020).
circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation.
eLife,
9, 1-29. Article e58478.
https://doi.org/10.7554/eLife.58478
Liu, X., Munk-Olsen, T., Albiñana, C., Vilhjálmsson, B. J., Pedersen, E. M., Schlünssen, V., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Nordentoft, M.
, Børglum, A. D., Werge, T., Hougaard, D. M.
, Mortensen, P. B. & Agerbo, E. (2020).
Genetic liability to major depression and risk of childhood asthma.
Brain, Behavior, and Immunity,
89, 433-439.
https://doi.org/10.1016/j.bbi.2020.07.030
Bodó, K., Baranzini, N., Girardello, R., Kokhanyuk, B., Németh, P.
, Hayashi, Y., Grimaldi, A. & Engelmann, P. (2020).
Nanomaterials and Annelid Immunity: A Comparative Survey to Reveal the Common Stress and Defense Responses of Two Sentinel Species to Nanomaterials in the Environment.
Biology,
9(10), 1-22. Article 307.
https://doi.org/10.3390/biology9100307Dou, Y., Barbosa, I., Jiang, H.
, Iasillo, C., Molloy, K. R., Schulze, W. M., Cusack, S.
, Schmid, M., Le Hir, H., LaCava, J.
& Jensen, T. H. (2020).
NCBP3 positively impacts mRNA biogenesis.
Nucleic Acids Research,
48(18), 10413-10427.
https://doi.org/10.1093/nar/gkaa744
Yan, Y., Chang, C., Su, J., Venø, M. T. & Kjems, J. (2020).
Osteoblastogenesis Alters Small RNA Profiles in EVs Derived from Bone Marrow Stem Cells (BMSCs) and Adipose Stem Cells (ASCs).
Biomedicines,
8(10), 1-17. Article 387.
https://doi.org/10.3390/biomedicines8100387
Musliner, K. L., Krebs, M. D.
, Albiñana, C., Vilhjalmsson, B., Agerbo, E., Zandi, P. P., Hougaard, D. M., Nordentoft, M.
, Børglum, A. D., Werge, T.
, Mortensen, P. B. & Østergaard, S. D. (2020).
Polygenic Risk and Progression to Bipolar or Psychotic Disorders Among Individuals Diagnosed With Unipolar Depression in Early Life.
The American Journal of Psychiatry,
177(10), 936-943.
https://doi.org/10.1176/appi.ajp.2020.19111195
Poulsen, E. T., Lumi, X.
, Hansen, A. K., Enghild, J. J. & Petrovski, G. (2020).
Protein Composition of the Subretinal Fluid Suggests Selective Diffusion of Vitreous Proteins in Retinal Detachment.
Translational vision science & technology,
9(11), 16. Article 16.
https://doi.org/10.1167/tvst.9.11.16
Chen, M., Maimaitili, M., Habekost, M., Gill, K. P., Mermet-Joret, N., Nabavi, S., Febbraro, F. & Denham, M. (2020).
Rapid generation of regionally specified CNS neurons by sequential patterning and conversion of human induced pluripotent stem cells.
Stem Cell Research,
48, Article 101945.
https://doi.org/10.1016/j.scr.2020.101945
Christensen, B., Toth, A. E., Nielsen, S. S. E., Scavenius, C., Petersen, S. V., Enghild, J. J., Rasmussen, J. T., Nielsen, M. S. & Sørensen, E. S. (2020).
Transport of a peptide from bovine αs1-casein across models of the intestinal and blood–brain barriers.
Nutrients,
12(10), Article 3157.
https://doi.org/10.3390/nu12103157
Lecordier, L., Uzureau, S.
, Vanwalleghem, G., Deleu, M., Crowet, J. M., Barry, P., Moran, B., Voorheis, P., Dumitru, A. C., Yamaryo-Botté, Y., Dieu, M., Tebabi, P., Vanhollebeke, B., Lins, L., Botté, C. Y., Alsteens, D., Dufrêne, Y., Pérez-Morga, D., Nolan, D. P. & Pays, E. (2020).
The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity.
iScience,
23(9), Article 101476.
https://doi.org/10.1016/j.isci.2020.101476Constantin, L., Poulsen, R. E., Scholz, L. A., Favre-Bulle, I. A., Taylor, M. A., Sun, B., Goodhill, G. J.
, Vanwalleghem, G. C. & Scott, E. K. (2020).
Altered brain-wide auditory networks in a zebrafish model of fragile X syndrome.
BMC Biology,
18(1), Article 125.
https://doi.org/10.1186/s12915-020-00857-6Zarantonello, A., Presumey, J., Simoni, L., Yalcin, E., Fox, R.
, Hansen, A., Olesen, H. G., Thiel, S., Johnson, M. B., Stevens, B.
, Laursen, N. S., Carroll, M. C.
& Andersen, G. R. (2020).
An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase.
Journal of Immunology,
205(6), 1678-1694.
https://doi.org/10.4049/jimmunol.2000528
O'Brien, T. R., Thomas, D. L., Jackson, S. S., Prokunina-Olsson, L., Donnelly, R. P.
& Hartmann, R. (2020).
Weak Induction of Interferon Expression by Severe Acute Respiratory Syndrome Coronavirus-2 Supports Clinical Trials of Interferon-λ to Treat Early Coronavirus Disease 2019.
Clinical Infectious Diseases,
71(6), 1410-12.
https://doi.org/10.1093/cid/ciaa453Christensen, L. F. B., Nowak, J. S., Sønderby, T. V., Frank, S. A. & Otzen, D. E. (2020).
Quantitating denaturation by formic acid: Imperfect repeats are essential to the stability of the functional amyloid protein FapC.
Journal of Biological Chemistry,
295(37), 13036-13041.
https://doi.org/10.1074/jbc.ra120.013396
Hao, D., Wang, X., Wang, X.
, Thomsen, B., Kadarmideen, H. N., Lan, X., Huang, Y. & Chen, H. (2020).
Transcriptomic changes in bovine skeletal muscle cells after resveratrol treatment.
Gene,
754, Article 144849.
https://doi.org/10.1016/j.gene.2020.144849
