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Department of Molecular Biology and Genetics

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Latest peer-reviewed publications at MBG

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Displaying results 3951 to 62 out of 62

Peer-reviewed publications at MBG - all years

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Preker, P., Nielsen, J., Kammler, S., Lykke-Andersen, S., Christensen, M. S., Mapendano, C. K., Schierup, M. H. & Jensen, T. H. (2008). RNA Exosome Depletion Reveals Transcription Upstream of Active Human Promoters. Science, 322(5909), 1851-1854. https://doi.org/10.1126/science.1164096

Krejci, P., Salazar, L., Kashiwada, T. A., Chlebova, K., Salasova, A., Thompson, L. M., Bryja, V., Kozubik, A. & Wilcox, W. R. (2008). Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage. PLoS One, 3(12), Article e3961. https://doi.org/10.1371/journal.pone.0003961

Sanggaard, K. W., Sonne-Schmidt, C. S., Hansen, T. P. K., Kristensen, T., Wisniewski, H.-G., Thøgersen, I. B. & Enghild, J. J. (2008). TSG-6 transfers proteins between glycosaminoglycans via a Ser28-mediated covalent catalytic mechanism. Journal of Biological Chemistry, 283(49), 33919-26. https://doi.org/10.1074/jbc.M804240200

Sato, T., Kurihara, Y., Asai, R., Kawamura, Y., Tonami, K., Uchijima, Y., Heude, E., Ekker, M., Levi, G. & Kurihara, H. (2008). An endothelin-1 switch specifies maxillomandibular identity. Proceedings of the National Academy of Sciences of the United States of America, 105(48), 18806-11. https://doi.org/10.1073/pnas.0807345105

Lorentzen, E., Basquin, J. & Conti, E. (2008). Structural organization of the RNA-degrading exosome. Curr. Opin. Struct. Biol., 18(6), 709-713.

Martos, V., Castreño, P., Valero Moreno, J. & de Mendoza, J. (2008). Binding to protein surfaces by supramolecular multivalent scaffolds. Current Opinion in Chemical Biology, 12(6), 698-706. https://doi.org/10.1016/j.cbpa.2008.08.024

Watanabe, T., Sato, T., Amano, T., Kawamura, Y., Kawamura, N., Kawaguchi, H., Yamashita, N., Kurihara, H. & Nakaoka, T. (2008). Dnm3os, a non-coding RNA, is required for normal growth and skeletal development in mice. Developmental Dynamics, 237(12), 3738-48. https://doi.org/10.1002/dvdy.21787

Kamei, H., Lu, L., Jiao, S., Li, Y., Nielsen, C. G., Laursen, L. S., Oxvig, C., Zhou, J. & Duan, C. (2008). Duplication and Diversification of the Hypoxia-Inducible IGFBP-1 Gene in Zebrafish. PLoS One, 3(8), e3091. https://doi.org/10.1371/journal.pone.0003091

Simonsen, M., Mailund, T. & Pedersen, C. N. S. (2008). Rapid neighbour-joining. In Algorithms in Bioinformatics - 8th International Workshop, WABI 2008, Proceedings (pp. 113-122) https://doi.org/10.1007/978-3-540-87361-7_10

Assenholt, J., Mouaikel, J., Andersen, K. R., Brodersen, D. E., Libri, D. & Jensen, T. H. (2008). Exonucleolysis is required for nuclear mRNA quality control in yeast THO mutants. RNA, 14(11), 2305-13. https://doi.org/10.1261/rna.1108008

Jensen, J. K. & Gettins, P. G. W. (2008). High-resolution structure of the stable plasminogen activator inhibitor type-1 variant 14-1B in its proteinase-cleaved form: a new tool for detailed interaction studies and modeling. Protein Science, 17(10), 1844-9. https://doi.org/10.1110/ps.036707.108

Munch, K., Boomsma, W., Huelsenbeck, J. P., Willerslev, E. & Nielsen, R. (2008). Statistical assignment of DNA sequences using Bayesian phylogenetics. Systematic Biology, 57(5), 750-757. https://doi.org/10.1080/10635150802422316

Li, Y., Kadarmideen, H. N. & Dekkers, J. C. M. (2008). Selection on multiple QTL with control of gene diversity and inbreeding for long-term benefit. Journal of Animal Breeding and Genetics, 125(5), 320-329. https://doi.org/10.1111/j.1439-0388.2007.00717.x

Madsen, B. E., Villesen, P. & Wiuf, C. (2008). Short tandem repeats in human exons: a target for disease mutations. BMC Genomics, 9, 410. https://doi.org/10.1186/1471-2164-9-410

Truhlar, S. M. E., Cervantes, C. F., Torpey, J. W., Kjærgaard, M. & Komives, E. A. (2008). Rapid mass spectrometric analysis of 15N-Leu incorporation fidelity during preparation of specifically labeled NMR samples. Protein Science, 17(9), 1636-9. https://doi.org/10.1110/ps.036418.108

Sanggaard, K. W., Sonne-Schmidt, C. S., Hansen, T. P. K., Lorentzen, K. A., Wisniewski, H.-G., Thøgersen, I. B. & Enghild, J. J. (2008). The transfer of heavy chains from bikunin proteins to hyaluronan requires both TSG-6 and HC2. Journal of Biological Chemistry, 283(27), 18530-18537. https://doi.org/10.1074/jbc.M800874200

Pauluhn, A., Ahmed, H., Lorentzen, E., Buchinger, S., Schomburg, D., Siebers, B. & Pohl, E. (2008). Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax. Proteins, 72(1), 35-43.

Nygaard, J. V., Andersen, M. Ø., Howard, K. A., Foss, M., Bünger, C., Kjems, J. & Besenbacher, F. (2008). Investigation of particle-functionalized tissue engineering scaffolds using X-ray tomographic microscopy. Biotechnology and Bioengineering (Print), 100(4), 820-9. https://doi.org/10.1002/bit.21796

Fredslund, F., Laursen, N. S., Roversi, P., Jenner, L. B., Oliveira, C. L. P., Pedersen, J. S., Nunn, M. A., Lea, S. M., Discipio, R., Sottrup-Jensen, L. & Andersen, G. R. (2008). Structure of and influence of a tick complement inhibitor on human complement component 5. Nature Immunology, 9(7), 753-60. https://doi.org/10.1038/ni.1625

Jensen, M. M., Christensen, M. S., Bonven, B. & Jensen, T. H. (2008). Requirements for chromatin reassembly during transcriptional downregulation of a heat shock gene in Saccharomyces cerevisiae. FEBS journal, 275(11), 2956-64. https://doi.org/10.1111/j.1742-4658.2008.06451.x

Karacaören, B. & Kadarmideen, H. N. (2008). Principal component and clustering analysis of functional traits in Swiss dairy cattle. Turkish Journal of Veterinary and Animal Sciences, 32(3), 163-171.

Buch-Pedersen, M. J., Pedersen, B. P., Nissen, P. & Palmgren, M. (2008). Protons and how they are transported by proton pumps. Pflügers Archiv - European Journal of Physiology, 457(3), 573-9.

Thomasen, J. R., Guldbrandtsen, B., Sørensen, P., Thomsen, B. & Lund, M. S. (2008). Quantitative Trait Loci Affecting Calving Traits in Danish Holstein Cattle. Journal of Dairy Science, 91(5), 2098-2105. https://doi.org/10.3168/jds.2007-0602

Thomsen, R., Saguez, C., Nasser, T. & Jensen, T. H. (2008). General, rapid, and transcription-dependent fragmentation of nucleolar antigens in S. cerevisiae mRNA export mutants. RNA, 4, 706-716. https://doi.org/10.1261/rna.718708

Kronborg, C. S., Knudsen, U. B. & Martensen, P. M. (2008). Differential regulation of the interferon induced gene ISG12A by serum from healthy and preeclamptic pregnancies. Cytokine, 42(1), 105-112. https://doi.org/10.1016/j.cyto.2008.01.008

Lorentzen, E., Basquin, J., Tomecki, R., Dziembowski, A. & Conti, E. (2008). Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family. Mol. Cell., 29(6), 717-728.

Ank, N., Iversen, M. B., Bartholdy, C., Staeheli, P., Hartmann, R., Jensen, U. B., Dagnæs-Hansen, F., Thomsen, A., Chen, Z., Haugen, H., Klucher, K. & Paludan, S. R. (2008). An Important Role for Type III Interferon (IFN-l/IL-28) in TLR-Induced Antiviral Activity. Journal of Immunology, 180(4), 2474-2485. https://doi.org/10.4049/jimmunol.180.4.2474

Ank, N., Iversen, M. B., Bartholdy, C., Staeheli, P., Hartmann, R., Jensen, U. B., Dagnaes-Hansen, F., Thomsen, A. R., Chen, Z., Haugen, H., Klucher, K. & Paludan, S. R. (2008). An important role for type III interferon (IFN-λ/IL-28) in TLR-induced antiviral activity. Journal of Immunology, 180(4), 2474-2485.

Damgaard, C. K., Kahns, S., Lykke-Andersen, S., Nielsen, A. L., Jensen, T. H. & Kjems, J. (2008). A 5' splice site enhances the recruitment of basal transcription initiation factors in vivo. Molecular Cell, 29(2), 271-278. https://doi.org/10.1016/j.molcel.2007.11.035, https://doi.org/10.1016/j.molcel.2007.11.035

Kadarmideen, H. N. (2008). Biochemical, ECF18R, and RYR1 gene polymorphisms and their associations with osteochondral diseases and production traits in pigs. Biochemical Genetics, 46(1-2), 41-53. https://doi.org/10.1007/s10528-007-9127-5

Sato, T., Kawamura, Y., Asai, R., Amano, T., Uchijima, Y., Dettlaff-Swiercz, D. A., Offermanns, S., Kurihara, Y. & Kurihara, H. (2008). Recombinase-mediated cassette exchange reveals the selective use of Gq/G11-dependent and -independent endothelin 1/endothelin type A receptor signaling in pharyngeal arch development. Development, 135(4), 755-65. https://doi.org/10.1242/dev.012708

Kurihara, Y., Kawamura, Y., Uchijima, Y., Amamo, T., Kobayashi, H., Asano, T. & Kurihara, H. (2008). Maintenance of genomic methylation patterns during preimplantation development requires the somatic form of DNA methyltransferase 1. Developmental Biology, 313(1), 335-46. https://doi.org/10.1016/j.ydbio.2007.10.033

Odadzic, D., Bramsen, J. B., Smicius, R., Bus, C., Kjems, J. & Engels, J. W. (2008). Synthesis of 2'-O-modified adenosine building blocks and application for RNA interference. Bioorganic & Medicinal Chemistry, 16(1), 518-529. https://doi.org/10.1016/j.bmc.2007.09.019

Torralba, S., Sojat, J. & Hartmann, R. (2008). 2'-5' oligoadenylate synthetase shares active site architecture with the archaeal CCA-adding enzyme. Cellular and Molecular Life Sciences, 65(16), 2613-20. https://doi.org/10.1007/s00018-008-8164-5

Dong, M., Hovgaard, M. B., Mamdouh, W., Xu, S., Otzen, D. & Besenbacher, F. (2008). AFM-based force spectroscopy measurements of mature amyloid fibrils of the peptide glucagon. Nanotechnology, 19, 384013. https://doi.org/10.1088/0957-4484/19/38/384013

Dong, M. D., Hovgaard, M. B., Mamdouh, W., Xu, S. L., Otzen, D. E. & Besenbacher, F. (2008). AFM-based force spectroscopy measurements of mature amyloid fibrils of the peptide glucagon: Nanotechnology. Nanotechnology, 19(38).

Djernes, J. K., Gulmann, N. C., Ibsen, M., Foldager, L., Olesen, F. & Munk-Jørgensen, P. (2008). A follow-up of elderly depressed patients. Nordic Journal of Psychiatry, 62(3), 233-41. https://doi.org/10.1080/08039480802088296

Otzen, D., Nesgaard, L., Andersen, K. K., Hansen, J. H., Christiansen, G., Doe, H. & Sehgal, P. (2008). Aggregation of S6 in a quasi-native state by monomeric SDS. Biochimica et biophysica acta - Biomembranes, (1784), 400-414.

Sander, M., Avlund, K., Lauritzen, M., Gottlieb, T., Halliwell, B., Stevnsner, T., Wewer, U. & Bohr, V. A. (2008). Aging-from molecules to populations. Mechanisms of Ageing and Development, 129(10), 614-23. https://doi.org/10.1016/j.mad.2008.08.002

Andersen, K. K., Westh, P. & Otzen, D. (2008). A global study of myoglobin-surfactant interactions. Langmuir, 15, 399-407.

Pedersen, J. S. & Otzen, D. (2008). Amyloid - a state in many guises: survival of the fittest fibril fold. Protein Science, 17, 1-9.

Larsen, P., Nielsen, J. L. & Otzen, D. (2008). Amyloid-like adhesins in floc-forming and filamentous bacteria in activated sludge. Applied and Environmental Microbiology, 74, 1517-1526.

Mallorquí-Fernández, N., Manandhar, SP., Mallorquí-Fernández, G., Usón, I., Wawrzonek, K., Kantyka, T., Solà, M., Thøgersen, I., Enghild, J. J., Potempa, J. & Gomis-Rüth, FX. (2008). A New Autocatalytic Activation Mechanism for Cysteine Proteases Revealed by Prevotella intermedia Interpain A. Journal of Biological Chemistry.

Fens, M. H., Mastrobattista, E., de Graaf, A. M., Flesch, F. M., Ultee, A., Rasmussen, J. T., Molema, G., Storm, G. & Schiffelers, R. M. (2008). Angiogenic endothelium shows lactadherin-dependent phagocytosis of aged erythrocytes and apoptotic cells. Blood, 111(9), 4542-4550.

Appenzeller-Herzog, C., Riemer, J., Christensen, B., Sørensen, E. S. & Ellgaard, L. (2008). A Novel Disulfide Switch Mechanism in Ero1a Balances ER Oxidation in Human Cells. EMBO Journal, 27, 2977-2987.

Bødtkjer, E., Prætorius, J., Füchtbauer, E.-M. & Aalkjær, C. (2008). Antibody-independent localization of the electroneutral Na⁺-HCO₃^- cotransporter NBCn1 (slc4a7) in mice. American Journal of Physiology: Cell Physiology, 294(2), C591-C603.

Haaning, S., Radutoiu, S., Hoffmann, S. V., Dittmer, J., Giehm, L., Otzen, D. & Stougaard, J. (2008). An unusual intrinsically disordered protein from the model legume Lotus japonicus stabilizes proteins in vitro. Journal of Biological Chemistry, 283(45), 31142-52. https://doi.org/10.1074/jbc.M805024200

Mathiasen, L., Dupont, D. M., Christensen, A., Blouse, G., Jensen, J. K., Gils, A., Declerck, P. J., Wind, T. & Andreasen, P. (2008). A peptide accelerating the conversion of plasminogen activator inhibitor-1 to an inactive latent state. Molecular Pharmacology, 74(3), 641-653.

Fadista, J., Nygaard, M., Holm, L.-E., Thomsen, B. & Bendixen, C. (2008). A snapshot of CNVs in the pig genome. PLoS One, 3(12), e3916. https://doi.org/10.1371/journal.pone.0003916

Nielsen, L. F., Schendel, D., Grove, J., Hvidtjørn, D., Jacobsson, B., Josiassen, T. L., Vestergaard, M., Uldall, P. & Thorsen, P. (2008). Asphyxia-related risk factors and their timing in spastic cerebral palsy. B J O G, 115(12), 1518-1528. https://doi.org/10.1111/j.1471-0528.2008.01896.x

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Lisbeth Heilesen