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Latest peer-reviewed publications at MBG

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Displaying results 251 to 62 out of 62

Peer-reviewed publications at MBG - all years

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Broksø, A. D., Bendixen, L., Fammé, S., Mikkelsen, K., Jensen, T. I. & Bak, R. O. (2025). Orthogonal transcriptional modulation and gene editing using multiple CRISPR/Cas systems. Molecular Therapy, 33(1), 71-89. https://doi.org/10.1016/j.ymthe.2024.11.024

Mohr, M., Kozikowska, J., Petryszyn, Z., Ostrowska, K., Golusińska-Kardach, E., Golusiński, W., Suchorska, W. & Kulcenty, K. (2025). Interplay between hypoxia, RNA methylation, and HPV in head and neck squamous cell carcinomas: drivers of oncogenesis and resistance to therapy . EXCLI Journal, 24, 1767-1796. https://doi.org/10.17179/excli2025-8834

Car, J., Ong, Q. C., Erlikh Fox, T., Leightley, D., Kemp, S. J., Švab, I., Tsoi, K. K. F., Sam, A. H., Kent, F. M., Hertelendy, A. J., Longhurst, C. A., Powell, J., Hamdy, H., Nguyen, H. V. Q., Aoun Bahous, S., Wang, M., Baumgartner, M., Mahendradhata, Y., Popovic, N. ... Digital Health Systems Collaborative (2025). The Digital Health Competencies in Medical Education Framework: An International Consensus Statement Based on a Delphi Study. JAMA network open, 8(1), Article e2453131. https://doi.org/10.1001/jamanetworkopen.2024.53131

Ho, K. H., Trapp, M., Guida, C., Ivanova, E. L., De Jaime-Soguero, A., Jabali, A., Thomas, C., Salasova, A., Bernatík, O., Salio, C., Horschitz, S., Hasselblatt, M., Sassoe-Pognetto, M., Čajánek, L., Ishikawa, H., Schroten, H., Schwerk, C., Acebrón, S. P., Angel, P. ... Patrizi, A. (2025). Activation of Wnt/β-catenin signaling is critical for the tumorigenesis of choroid plexus. Neuro-Oncology, 27(1), 106-122. https://doi.org/10.1093/neuonc/noae176, https://doi.org/10.1093/neuonc/noae176

Bøtkjær, J. A., Poulsen, L. L. C., Noer, P. R., Grøndahl, M. L., Englund, A. L. M., Franks, S., Hardy, K., Oxvig, C. & Andersen, C. Y. (2025). Dynamics of IGF Signaling During the Ovulatory Peak in Women Undergoing Ovarian Stimulation. The Journal of clinical endocrinology and metabolism, 110(1), e160-e167. https://doi.org/10.1210/clinem/dgae132

Biswas, D., Liu, Y. H., Herrero, J., Wu, Y., Moore, D. A., Karasaki, T., Grigoriadis, K., Lu, W. T., Veeriah, S., Naceur-Lombardelli, C., Magno, N., Ward, S., Frankell, A. M., Hill, M. S., Colliver, E., de Carné Trécesson, S., East, P., Malhi, A., Snell, D. M. ... TRACERx Consortium (2025). Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma. Nature Cancer, 6(1), 86-101. Article 10110. https://doi.org/10.1038/s43018-024-00883-1

Prip, F., Lamy, P., Lindskrog, S. V., Strandgaard, T., Nordentoft, I., Birkenkamp-Demtröder, K., Birkbak, N. J., Kristjánsdóttir, N., Kjær, A., Andreasen, T. G., Ahrenfeldt, J., Pedersen, J. S., Rasmussen, A. M., Hermann, G. G., Mogensen, K., Petersen, A. C., Hartmann, A., Grimm, M. O., Horstmann, M. ... UROMOL Consortium (2025). Comprehensive genomic characterization of early-stage bladder cancer. Nature Genetics, 57(1), 115-125. Article 2301. https://doi.org/10.1038/s41588-024-02030-z

Rashidi, A., Füchtbauer, E. M., Vahabzadeh, Z., Soleimani, F., Rahimi, K., Nikkhoo, B., Fakhari, S., Erfan, M. B. K., Azarnezhad, A., Pooladi, A., Soheili, F. & Fathi, F. (2025). CRISPR/Cas9-mediated knockout of DYRK1B in triple-negative breast cancer cells: implications for cell proliferation, apoptosis, and therapeutic sensitivity. Biochemical Engineering Journal, 213, Article 109553. https://doi.org/10.1016/j.bej.2024.109553

Luige, J., Conrad, T., Armaos, A., Louloupi, A., Vincent, A., Meierhofer, D., Gajhede, M., Tartaglia, G. G. & Ørom, U. A. V. (2025). Design and characterization of G-quadruplex RNA aptamers reveal RNA-binding by KDM5 lysine demethylases. Computational and Structural Biotechnology Journal, 27, 2719-2729. https://doi.org/10.1016/j.csbj.2025.06.027

Gadegaard, I. S. E., Madsen, C. M., Johansen, P. M. & Rasmussen, J. T. (2025). Distribution, activity, and storage of xanthine oxidase in bovine milk fractions. International Dairy Journal, 160, Article 106091. https://doi.org/10.1016/j.idairyj.2024.106091

Shrestha, M., Bai, Z., Gholipourshahraki, T., Hjelholt, A. J., Hu, S., Kjolby, M., Rohde, P. D. & Sørensen, P. (2025). Enhanced genetic fine mapping accuracy with Bayesian Linear Regression models in diverse genetic architectures. PLoS Genetics, 21(7), 1-30. Article e1011783. https://doi.org/10.1371/journal.pgen.1011783

Sarrette, B., Luu, T. B., Johansson, A., Fliegmann, J., Pouzet, C., Pichereaux, C., Remblière, C., Sauviac, L., Carles, N., Amblard, E., Guyot, V., Bonhomme, M., Cullimore, J., Gough, C., Jacquet, C. & Pauly, N. (2025). Medicago truncatula SOBIR1 controls pathogen immunity and specificity in the Rhizobium-legume symbiosis. Plant, Cell and Environment, 48(1), 32-50. https://doi.org/10.1111/pce.15071

Buhl, E. H., Christensen, B., Pedersen, F. H. & S⊘rensen, E. S. (2025). Milk osteopontin has high iron-binding capacity and facilitates iron absorption in intestinal cells. Journal of Dairy Science, 108(1), 90-100. https://doi.org/10.3168/jds.2024-25305

Nel, L., Thaysen, K., Jamecna, D., Olesen, E., Langer, J., Frain, K. M., Szomek, M., Höglinger, D., Wüstner, D. & Pedersen, B. P. (2025). Structural and biochemical analysis of ligand binding in yeast Niemann–Pick type C1–related protein. Life Science Alliance, 8(1), Article e202402990. https://doi.org/10.26508/lsa.202402990

TRACERx Consortium (2025). TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling. Nature Cell Biology, 27(1), 154-168. Article 4871. https://doi.org/10.1038/s41556-024-01558-w

TRACERx Consortium (2025). Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma. Nature Medicine, 31(1), 70-76. https://doi.org/10.1038/s41591-024-03216-y

Shiraz, M. G., Nielsen, J., Widmann, J., Chung, K. H. K., Davis, T. P., Rasmussen, C., Scavenius, C., Enghild, J. J., Martin-Gallausiaux, C., Singh, Y., Javed, I. & Otzen, D. E. (2025). Young rat microbiota extracts strongly inhibit fibrillation of α-synuclein and protect neuroblastoma cells and zebrafish against α-synuclein toxicity. Molecules and Cells, 48(1), Article 100161. https://doi.org/10.1016/j.mocell.2024.100161

Pedersen, E. M., Steinbach, J., Pedersen, C. B., Schork, A. J., Krebs, M. D., Vilhjálmsson, B. J. & Privé, F. (2025). Automatic detection of n-degree family members. Frontiers in Genetics, 16, Article 1708315. https://doi.org/10.3389/fgene.2025.1708315

Nguyen, M. T. A., Andersen, E. S. & Pothoulakis, G. (2025). Construction of Small Genes with Repetitive Elements Using Oligo Extension and Golden Gate Assembly. In D. Schindler (Ed.), Golden Gate Cloning (pp. 219-227). Humana Press. https://doi.org/10.1007/978-1-0716-4220-7_12

Jensen, R. K., Miehe, M., Gandini, R., Jørgensen, M. H., Spillner, E. & Andersen, G. R. (2025). Cryo-EM Structure of FcεRI Bound IgE Reveals Multiple Defined Conformations of the Fab-Fc Hinge. Allergy: European Journal of Allergy and Clinical Immunology. Advance online publication. https://doi.org/10.1111/all.70132

de Evan, T., Foldager, L. & Weisbjerg, M. R. (2025). Dairy cow phenotypes related to methane yield. 315. Abstract from 9th GGAA, International Greenhouse Gas & Animal Agriculture Conference, Nairobi, Kenya. https://ggaaconference.org/storage/2026/01/GGAA2025-bookofabstracts-NIBIOBook11-9.pdf

Walpole, S., Santiago-Vela, M. I., Birkedal, U., Hong, Z., Ros, X. B. D., van Overeem Hansen, T. & Wadt, K. A. W. (2025). Functional Analysis and Clinical Data Reclassify the DICER1 c.4206+1G>C Variant, Leading to Exon 22 Skipping, as Likely Pathogenic. Clinical Genetics. Advance online publication. https://doi.org/10.1111/cge.70110

Wakabayashi, T., Andersen, S. U., Tanaka, S., Sato, S., Kawaguchi, M., Kato, K. & Setoguchi, H. (2025). Genome-wide association study identifies candidate genes contributing to flowering time variation in Lotus japonicus in Japan. Plant Biotechnology, 42(1), 17-29. https://doi.org/10.5511/plantbiotechnology.24.1023a

Teixeira, L. M. C., Paiva, P., Johansen, M. B., Sommerfeldt, A., Petersen, A. R., Rotilio, L., Sandahl, A., Morth, J. P., Westh, P., Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025). Hydrolysis of the Urethane Bond Catalyzed by Pseudomonas sp. MIS38 Lipase: A QM/MM Mechanistic Insight. ACS Catalysis, 15, 14728-14740. https://doi.org/10.1021/acscatal.5c03228

Peña-Díaz, S., Manglano-Artuñedo, Z., Pinheiro, F. & Ventura, S. (2025). Identification of α-Synuclein Aggregation Inhibitors via High-Throughput Screening. In Neuromethods (pp. 61-85). The Humana Press Inc.. https://doi.org/10.1007/978-1-0716-4232-0_3

da Fonseca Junior, A. M., Ispada, J., de Lima , C. B., Trabuco do Amaral, D., Juan Ross, P., Kadarmideen, H. & Pecora Milazzoto, M. (2025). Multiomics integration uncovers metabolic control of H3K27ac in bovine inner cell masses. Biology of Reproduction, 1-10. Advance online publication. https://doi.org/10.1093/biolre/ioaf244

Baindoor, S., Gibriel, H. A. Y., Kool, L., Su, J., Demaegd, K. C., Venø, M. T., Van Den Berg, L. H., Kjems, J., Van Es, M. A. & Prehn, J. H. M. (2025). Serum small non-coding RNA define molecular subtypes in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. Advance online publication. https://doi.org/10.1080/21678421.2025.2574690

ICTV Taxonomy Summary Consortium (2025). Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Fungal and Protist Viruses Subcommittee, 2025. The Journal of general virology, 106(7), Article 002115. https://doi.org/10.1099/jgv.0.002115

Selten, G., Gómez-Repollés, A., Lamouche, F., Radutoiu, S. & de Jonge, R. (2025). SyFi: generating and using sequence fingerprints to distinguish SynCom isolates. Microbial Genomics, 11(9), Article 001461. https://doi.org/10.1099/mgen.0.001461

Kofod Petersen, A., Villesen, P. & Staun Larsen, L. (2025). The oral fingerprint: rapid 3D comparison of palatal rugae for forensic identification. Frontiers in Radiology, 5, Article 1638294. https://doi.org/10.3389/fradi.2025.1638294

Fedosov, S. N. (2025). The uptake of ingested vitamin B12 and its total body balance: a mathematical model suggests the optimal supplementation strategy. Biochimie. Advance online publication. https://doi.org/10.1016/j.biochi.2025.12.002

Paiva, P., Teixeira, L. M. C., Ferreira, P., Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025). Transforming Computational Power into Environmental Solutions: HPC-driven Research on Urethanase-mediated Plastic Degradation. Procedia Computer Science, 267, 207-217. https://doi.org/10.1016/j.procs.2025.08.247

Paiva, P., Teixeira, L. M. C., Wei, R., Liu, W., Weber, G., Morth, J. P., Westh, P., Petersen, A. R., Johansen, M. B., Sommerfeldt, A., Sandahl, A., Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025). Unveiling the enzymatic pathway of UMG-SP2 urethanase: insights into polyurethane degradation at the atomic level. Chemical Science, 16(5), 2437-2452. https://doi.org/10.1039/d4sc06688j

de Evan, T., Wang, W., Foldager, L. & Weisbjerg, M. R. (2025). Variation in individual cow’s response to methane-reducing additives. 110. Abstract from 9th GGAA, International Greenhouse Gas & Animal Agriculture Conference, Nairobi, Kenya. https://ggaaconference.org/storage/2026/01/GGAA2025-bookofabstracts-NIBIOBook11-9.pdf

Etzerodt, A., Mikkelsen, J. H., Torvund-Jensen, M., Hennig, D., Boesen, T., Graversen, J. H., Moestrup, S. K., Kollman, J. M. & Andersen, C. B. F. (2024). The Cryo-EM structure of human CD163 bound to haptoglobin-hemoglobin reveals molecular mechanisms of hemoglobin scavenging. Nature Communications, 15(1), Article 10871. https://doi.org/10.1038/s41467-024-55171-4

Borg, K. N., Shetty, A., Cheng, G., Zhu, S., Wang, T., Yuan, W., Ho, H. P., Knudsen, B. R., Tesauro, C. & Ho, Y. P. (2024). Hydrogel bead-based isothermal detection (BEAD-ID) for assessing the activity of DNA-modifying enzymes. iScience, 27(12), Article 111332. https://doi.org/10.1016/j.isci.2024.111332

Borg, K. N., Shetty, A., Cheng, G., Zhu, S., Wang, T., Ho, H. P., Knudsen, B. R., Tesauro, C. & Ho, Y.-P. (2024). Hydrogel bead-based isothermal detection (BEAD-ID) for assessing the activity of DNA-modifying enzymes. iScience, 27(12), Article 111332. https://doi.org/10.1016/j.isci.2024.111332

Korhonen, S., Stenberg, K., Seemab, U., Bartos, P., Mäkiniemi, K., Kjems, J., Dupont, D. M. & Subrizi, A. (2024). Targeting ocular tissues with intravenously administered aptamers selected by in vivo SELEX. Molecular Therapy Nucleic Acids, 35(4), Article 102352. https://doi.org/10.1016/j.omtn.2024.102352

Pedersen, E. M., Wimberley, T. & Vilhjálmsson, B. J. (2024). A cautionary tale for Alzheimer’s disease GWAS by proxy: Genetic epidemiology. Nature Genetics, 56(12), 2590-2591. Article 99. https://doi.org/10.1038/s41588-024-02023-y

Breinbjerg, A., Jørgensen, C. S., Walters, G. B., Grove, J., Als, T. D., Kamperis, K., Stéfansdóttir, L., Thirstrup, J. P., Borg, B., Albiñana, C., Vilhjálmsson, B. J., Eðvarðsson, V. Ö., Stefánsson, H., Mortensen, P. B., Agerbo, E., Werge, T., Børglum, A., Demontis, D., Stefánsson, K. ... Christensen, J. H. (2024). Exploring the Genetic Risk of Childhood Daytime Urinary Incontinence: A Genome-Wide Association Study. The Journal of Urology, 212(6), 851-861. https://doi.org/10.1097/JU.0000000000004187

Yamamoto, S., Nakamura, H., Kawamura, Y. K., Kitazawa, T., Kimura, M. & Kitazawa, Y. (2024). Alkoxy Substituted Brominated closo-Dodecaborates with Functionalized Aliphatic Spacers. Chemistry, 6(6), 1635-1644. https://doi.org/10.3390/chemistry6060099

Montalbano, S., Krebs, M. D., Rosengren, A., Vaez, M., Hellberg, K. L. G., Mortensen, P. B., Børglum, A. D., Geschwind, D. H., Raznahan, A., Thompson, W. K., Helenius, D., Werge, T., Ingason, A. & iPSYCH Investigators (2024). Analysis of exonic deletions in a large population study provides novel insights into NRXN1 pathology. npj Genomic Medicine, 9(1), Article 67. https://doi.org/10.1038/s41525-024-00450-8

Vieira de Sá, R., Sudria-Lopez, E., Cañizares Luna, M., Harschnitz, O., van den Heuvel, D. M. A., Kling, S., Vonk, D., Westeneng, H. J., Karst, H., Bloemenkamp, L., Varderidou-Minasian, S., Schlegel, D. K., Mars, M., Broekhoven, M. H., van Kronenburg, N. C. H., Adolfs, Y., Vangoor, V. R., de Jongh, R., Ljubikj, T. ... Pasterkamp, R. J. (2024). ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes. Nature Communications, 15(1), Article 7484. https://doi.org/10.1038/s41467-024-51676-0