Department of Molecular Biology and Genetics

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 Department of Molecular Biology and Genetics Research Research areas Neurobiology

Neurobiology

[Translate to English:] DANDRITE's logo

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE 

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.  

Groups at DANDRITE encompass ambitious research programs that include:

  • Molecular and cellular mechanisms of memory
  • Effort-based decision making
  • Neuronal development and stem cells
  • Motor control
  • Brain processing of vision
  • Neurological and neurodegenerative diseases
  • Psychiatric disorders
  • Neurotrophic receptors, sorting
  • Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

Group leaders

Professors

Associate Professors

Tenure Track Assistant Professor

Professor

Associate Professors

Tenure Track Assistant Professor

Peer-reviewed publications

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Saleh, N., Wang, Y., Nissen, P. & Lindorff-Larsen, K. (2019). Allosteric modulation of the sarcoplasmic reticulum Ca2+ ATPase by thapsigargin via decoupling of functional motions. Physical Chemistry Chemical Physics, 21(39), 21991-21995. https://doi.org/10.1039/c9cp04736k
Strauss, M. J., Asheghali, D., Evans, A. M., Li, R. L., Chavez, A. D., Sun, C., Becker, M. L. & Dichtel, W. R. (2019). Cooperative Self-Assembly of Pyridine-2,6-Diimine-Linked Macrocycles into Mechanically Robust Nanotubes. Angewandte Chemie International Edition, 58(41), 14708-14714. https://doi.org/10.1002/anie.201907668
Bonaventura, J., Eldridge, M. A. G., Hu, F., Gomez, J. L., Sanchez-Soto, M., Abramyan, A. M., Lam, S., Boehm, M. A., Ruiz, C., Farrell, M. R., Moreno, A., Galal Faress, I. M., Andersen, N., Lin, J. Y., Moaddel, R., Morris, P. J., Shi, L., Sibley, D. R., Mahler, S. V. ... Michaelides, M. (2019). High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nature Communications, 10(1), Article 4627. https://doi.org/10.1038/s41467-019-12236-z
Zhang, Y., Gal, N., Itel, F., Westensee, I. N., Brodszkij, E., Mayer, D., Stenger, S., Castellote-Borrell, M., Boesen, T., Tabaei, S. R., Hook, F. & Stadler, B. (2019). Hybrid vesicles as intracellular reactive oxygen species and nitric oxide generators. Nanoscale, 11(24), 11530-11541. https://doi.org/10.1039/c9nr02584g
Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, O., Lousen, R., Bucciarelli, S., Mehta, V., Sellés-Baiget, S., Solbak, S. M. Ø., Bach, A., Mesa, P., Hernandez, P. A., Montoya, G., Nguyen, T. T. T. N., Rand, K. D., Boesen, T. & Gajhede, M. (2019). Molecular architecture of the Jumonji C family histone demethylase KDM5B. Scientific Reports, 9(1), Article 4019. https://doi.org/10.1038/s41598-019-40573-y
Kidmose, R. T., Juhl, J., Nissen, P., Boesen, T., Karlsen, J. L. & Pedersen, B. P. (2019). Namdinator - Automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps. IUCrJ, 6(4), 526-531. https://doi.org/10.1107/S2052252519007619
Kjeldsen, K. U., Schreiber, L., Thorup, C. A., Boesen, T., Bjerg, J. T., Yang, T., Dueholm, M. S., Larsen, S., Risgaard-Petersen, N., Nierychlo, M., Schmid, M., Bøggild, A., van de Vossenberg, J., Geelhoed, J. S., Meysman, F. J. R., Wagner, M., Nielsen, P. H., Nielsen, L. P. & Schramm, A. (2019). On the evolution and physiology of cable bacteria. Proceedings of the National Academy of Sciences (PNAS), 116(38), 19116-19125. https://doi.org/10.1073/pnas.1903514116
Elfarrash, S., Jensen, N. M., Ferreira, N., Betzer, C., Thevathasan, J. V., Diekmann, R., Adel, M., Omar, N. M., Boraie, M. Z., Gad, S., Ries, J., Kirik, D., Nabavi, S. & Jensen, P. H. (2019). Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates. Acta Neuropathologica Communications, 7(1), Article 213. https://doi.org/10.1186/s40478-019-0865-5
Wang, S., Chavez, A. D., Thomas, S., Li, H., Flanders, N. C., Sun, C., Strauss, M. J., Chen, L. X., Markvoort, A. J., Bredas, J. L. & Dichtel, W. R. (2019). Pathway Complexity in the Stacking of Imine-Linked Macrocycles Related to Two-Dimensional Covalent Organic Frameworks. Chemistry of Materials, 31(17), 7104-7111. https://doi.org/10.1021/acs.chemmater.9b03088
Dyla, M., Basse Hansen, S., Nissen, P. & Kjaergaard, M. (2019). Structural dynamics of P-type ATPase ion pumps. Biochemical Society Transactions, 47(5), 1247-1257. https://doi.org/10.1042/BST20190124
Timcenko, M., Lyons, J. A., Januliene, D., Ulstrup, J. J., Dieudonné, T., Montigny, C., Ash, M. R., Karlsen, J. L., Boesen, T., Kühlbrandt, W., Lenoir, G., Moeller, A. & Nissen, P. (2019). Structure and autoregulation of a P4-ATPase lipid flippase. Nature, 571(7765), 366-370. https://doi.org/10.1038/s41586-019-1344-7
Sitsel, A., De Raeymaecker, J., Drachmann, N. D., Derua, R., Smaardijk, S., Andersen, J. L., Vandecaetsbeek, I., Chen, J., De Maeyer, M., Waelkens, E., Olesen, C., Vangheluwe, P. & Nissen, P. (2019). Structures of the heart specific SERCA2a Ca 2+ -ATPase. EMBO Journal, 38(5), Article e100020. https://doi.org/10.15252/embj.2018100020

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Revised 13.11.2025
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Helene Eriksen