Department of Molecular Biology and Genetics

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Neurobiology

[Translate to English:] DANDRITE's logo

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE 

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.  

Groups at DANDRITE encompass ambitious research programs that include:

  • Molecular and cellular mechanisms of memory
  • Effort-based decision making
  • Neuronal development and stem cells
  • Motor control
  • Brain processing of vision
  • Neurological and neurodegenerative diseases
  • Psychiatric disorders
  • Neurotrophic receptors, sorting
  • Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

Group leaders

Professors

Associate Professors

Tenure Track Assistant Professor

Professor

Associate Professors

Tenure Track Assistant Professor

Peer-reviewed publications

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Geurts, M. M. G., Clausen, J. D., Arnou, B., Montigny, C., Lenoir, G., Corey, R. A., Jaxel, C., Møller, J. V., Nissen, P., Andersen, J. P., Le Maire, M. & Bublitz, M. (2020). The SERCA residue Glu340 mediates interdomain communication that guides Ca2+transport. Proceedings of the National Academy of Sciences (PNAS), 117(49), 31114-31122. https://doi.org/10.1073/pnas.2014896117
Krauth, N., Khalil, V., Jariwala, M., Mermet-Joret, N., Vestergaard, A. K., Capogna, M. & Nabavi, S. (2020). TRACE: An Unbiased Method to Permanently Tag Transiently Activated Inputs. Frontiers in Cellular Neuroscience, 14, Article 114. https://doi.org/10.3389/fncel.2020.00114
Mohammad-Beigi, H., Scavenius, C., Jensen, P. B., Kjaer-Sorensen, K., Oxvig, C., Boesen, T., Enghild, J. J., Sutherland, D. S. & Hayashi, Y. (2020). Tracing the In Vivo Fate of Nanoparticles with a "Non-Self" Biological Identity. ACS Nano, 14(8), 10666-10679. https://doi.org/10.1101/2020.03.27.012146, https://doi.org/10.1021/acsnano.0c05178
Ravishankar, H., Pedersen, M. N., Eklund, M., Sitsel, A., Li, C., Duelli, A., Levantino, M., Wulff, M., Barth, A., Olesen, C., Nissen, P. & Andersson, M. (2020). Tracking Ca2+ ATPase intermediates in real time by x-ray solution scattering. Science Advances, 6(12), Article eaaz0981. https://doi.org/10.1126/sciadv.aaz0981
Gotfryd, K., Boesen, T., Mortensen, J. S., Khelashvili, G., Quick, M., Terry, D. S., Missel, J. W., LeVine, M. V., Gourdon, P., Blanchard, S. C., Javitch, J. A., Weinstein, H., Loland, C. J., Nissen, P. & Gether, U. (2020). X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release. Nature Communications, 11(1), Article 1005. https://doi.org/10.1038/s41467-020-14735-w
Saleh, N., Wang, Y., Nissen, P. & Lindorff-Larsen, K. (2019). Allosteric modulation of the sarcoplasmic reticulum Ca2+ ATPase by thapsigargin via decoupling of functional motions. Physical Chemistry Chemical Physics, 21(39), 21991-21995. https://doi.org/10.1039/c9cp04736k
Strauss, M. J., Asheghali, D., Evans, A. M., Li, R. L., Chavez, A. D., Sun, C., Becker, M. L. & Dichtel, W. R. (2019). Cooperative Self-Assembly of Pyridine-2,6-Diimine-Linked Macrocycles into Mechanically Robust Nanotubes. Angewandte Chemie International Edition, 58(41), 14708-14714. https://doi.org/10.1002/anie.201907668
Bonaventura, J., Eldridge, M. A. G., Hu, F., Gomez, J. L., Sanchez-Soto, M., Abramyan, A. M., Lam, S., Boehm, M. A., Ruiz, C., Farrell, M. R., Moreno, A., Galal Faress, I. M., Andersen, N., Lin, J. Y., Moaddel, R., Morris, P. J., Shi, L., Sibley, D. R., Mahler, S. V. ... Michaelides, M. (2019). High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nature Communications, 10(1), Article 4627. https://doi.org/10.1038/s41467-019-12236-z
Zhang, Y., Gal, N., Itel, F., Westensee, I. N., Brodszkij, E., Mayer, D., Stenger, S., Castellote-Borrell, M., Boesen, T., Tabaei, S. R., Hook, F. & Stadler, B. (2019). Hybrid vesicles as intracellular reactive oxygen species and nitric oxide generators. Nanoscale, 11(24), 11530-11541. https://doi.org/10.1039/c9nr02584g
Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, O., Lousen, R., Bucciarelli, S., Mehta, V., Sellés-Baiget, S., Solbak, S. M. Ø., Bach, A., Mesa, P., Hernandez, P. A., Montoya, G., Nguyen, T. T. T. N., Rand, K. D., Boesen, T. & Gajhede, M. (2019). Molecular architecture of the Jumonji C family histone demethylase KDM5B. Scientific Reports, 9(1), Article 4019. https://doi.org/10.1038/s41598-019-40573-y
Kidmose, R. T., Juhl, J., Nissen, P., Boesen, T., Karlsen, J. L. & Pedersen, B. P. (2019). Namdinator - Automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps. IUCrJ, 6(4), 526-531. https://doi.org/10.1107/S2052252519007619
Kjeldsen, K. U., Schreiber, L., Thorup, C. A., Boesen, T., Bjerg, J. T., Yang, T., Dueholm, M. S., Larsen, S., Risgaard-Petersen, N., Nierychlo, M., Schmid, M., Bøggild, A., van de Vossenberg, J., Geelhoed, J. S., Meysman, F. J. R., Wagner, M., Nielsen, P. H., Nielsen, L. P. & Schramm, A. (2019). On the evolution and physiology of cable bacteria. Proceedings of the National Academy of Sciences (PNAS), 116(38), 19116-19125. https://doi.org/10.1073/pnas.1903514116

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Revised 13.11.2025
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Helene Eriksen