Department of Molecular Biology and Genetics

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 Department of Molecular Biology and Genetics Research Research areas Neurobiology Gilles Vanwalleghem

Gilles Vanwalleghem
[Translate to English:] Legend: The six days old larval zebrafish expresses a fluorescent calcium reporter in all of its neurons, including in the enteric nervous system that regulates the gut. We use this transparent animal to image in vivo the activity of its neurons. Arrows indicate the rostral, dorsal, caudal, and ventral directions. Scale bar is 100 um.
Video legend: Live imaging of the activity of neurons in the guts of a six days old larval zebrafish, we can see the high motility of the guts driven by the waves of neuronal activity.

Featured articles

  • “Brain-wide mapping of water flow perception in zebrafish.” Vanwalleghem G, Schuster K, Taylor MA, Favre-Bulle IA, Scott EK. Journal of Neuroscience, doi: 10.1523/JNEUROSCI.0049-20.2020 (2020)
  • “Cellular resolution imaging of vestibular processing across the larval zebrafish brain” Favre-Bulle IA*, Vanwalleghem GC*, Taylor MA, Rubinsztein-Dunlop H, Scott EK. Current Biology. doi: 10.1016/j.cub.2018.09.060. (2018)
  • “Integrative whole-brain neuroscience in larval zebrafish" Vanwalleghem G, Ahrens MB and Scott EK. Current Opinion in Neurobiology. doi: 10.1016/j.conb.2018.02.004 (2018)

Peer-reviewed publications

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Andersen-Civil, A. I. S., Mantel, M., Soh, J., Mostowy, S., Brugman, S. & Vanwalleghem, G. C. (2025). Novel and unscrutinized immune entities of the zebrafish gut. FEBS Letters, 599(23), 3444-3455. https://doi.org/10.1002/1873-3468.70161
Andersen-Civil, A. I. S., Sawale, R. A. & Vanwalleghem, G. C. (2023). Zebrafish (Danio rerio) as a translational model for neuro-immune interactions in the enteric nervous system in autism spectrum disorders. Brain, Behavior, and Immunity, 112, 254-266. https://doi.org/10.1016/j.bbi.2023.06.001
Marquez-Legorreta, E., Constantin, L., Piber, M., Favre-Bulle, I. A., Taylor, M. A., Blevins, A. S., Giacomotto, J., Bassett, D. S., Vanwalleghem, G. C. & Scott, E. K. (2022). Brain-wide visual habituation networks in wild type and fmr1 zebrafish. Nature Communications, 13(1), Article 895. https://doi.org/10.1038/s41467-022-28299-4
Blevins, A. S., Bassett, D. S., Scott, E. K. & Vanwalleghem, G. C. (2022). From calcium imaging to graph topology. Network Neuroscience, 6(4), 1125-1147. https://doi.org/10.1162/netn_a_00262
Ahmed, I. A., Liu, J.-J., Gieniec, K. A., Bair-Marshall, C. J., Adewakun, A. B., Hetzler, B. E., Arp, C. J., Khatri, L., Vanwalleghem, G. C., Seidenberg, A. T., Cowin, P., Trauner, D., Chao, M. V., Davis, F. M., Tsien, R. W. & Froemke, R. C. (2022). Optopharmacological tools for precise spatiotemporal control of oxytocin signaling in the central nervous system and periphery. https://doi.org/10.1101/2022.11.10.516001

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[Translate to English:] gruppefoto
Revised 13.11.2025