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Department of Molecular Biology and Genetics

Neurobiology

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.

Groups at DANDRITE encompass ambitious research programs that include:

Molecular and cellular mechanisms of memory
Effort-based decision making
Neuronal development and stem cells
Motor control
Brain processing of vision
Neurological and neurodegenerative diseases
Psychiatric disorders
Neurotrophic receptors, sorting
Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

List of staff and students in the research group

Group leaders

Professors

Associate Professors

Tenure Track Assistant Professor

Gilles Claude Vanwalleghem

Professor

Associate Professors

Tenure Track Assistant Professor

Peer-reviewed publications

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De Ford, C., Calderón, C., Sehgal, P., Fedosova, N. U., Murillo, R., Olesen, C., Nissen, P., Møller, J. V. & Merfort, I. (2015). Discovery of Tricyclic Clerodane Diterpenes as Sarco/Endoplasmic Reticulum Ca²⁺-ATPase Inhibitors and Structure-Activity Relationships. Journal of Natural Products, 78(6), 1262-1270. https://doi.org/10.1021/acs.jnatprod.5b00062

Gorgel, M., Ulstrup, J., Bøggild, A., Jones, N. C., Hoffmann, S. V., Nissen, P. & Boesen, T. (2015). High-resolution structure of a type IV pilin from the metal-reducing bacterium Shewanella oneidensis. BMC Structural Biology, 15(4), 1-17. https://doi.org/10.1186/s12900-015-0031-7

Nass, K., Foucar, L., Barends, T. R. M., Hartmann, E., Botha, S., Shoeman, R. L., Doak, R. B., Alonso-Mori, R., Aquila, A., Bajt, S., Barty, A., Bean, R., Beyerlein, K. R., Bublitz, M., Drachmann, N., Gregersen, J., Jönsson, H. O., Kabsch, W., Kassemeyer, S. ... Schlichting, I. (2015). Indications of radiation damage in ferredoxin microcrystals using high-intensity X-FEL beams. Journal of Synchrotron Radiation, 22(2), 225-238. https://doi.org/10.1107/S1600577515002349

Autzen, H. E., Siuda, I., Sonntag, Y., Nissen, P., Møller, J. V. & Thøgersen, L. (2015). Regulation of the Ca(2+)-ATPase by cholesterol: A specific or non-specific effect? Molecular Membrane Biology, 32(3), 75-87. https://doi.org/10.3109/09687688.2015.1073382

Sun, C., Walker, K. L., Wakefield, D. L. & Dichtel, W. R. (2015). Retaining the Activity of Enzymes and Fluorophores Attached to Graphene Oxide. Chemistry of Materials, 27(12), 4499-4504. https://doi.org/10.1021/acs.chemmater.5b01954

Bublitz, M., Nass, K., Drachmann, N. D., Markvardsen, A. J., Gutmann, M. J., Barends, T. R. M., Mattle, D., Shoeman, R. L., Doak, R. B., Boutet, S., Messerschmidt, M., Seibert, M. M., Williams, G. J., Foucar, L., Reinhard, L., Sitsel, O., Gregersen, J. L., Clausen, J. D., Boesen, T. ... Schlichting, I. (2015). Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser. IUCrJ, 2(Pt 4), 409-420. https://doi.org/10.1107/S2052252515008969

Sitsel, O., Grønberg, C., Autzen, H., Wang, K., Meloni, G., Nissen, P. & Gourdon, P. (2015). Structure and function of Cu(I)- and Zn(II)-ATPases. Biochemistry, 54(37), 5673-5683. https://doi.org/10.1021/acs.biochem.5b00512

Laursen, M., Gregersen, J. L., Yatime, L., Nissen, P. & Fedosova, N. (2015). Structures and characterization of digoxin- and bufalin-bound Na⁺,K⁺-ATPase compared with the ouabain-bound complex. Proceedings of the National Academy of Sciences (PNAS), 112(6), 1755-1760. https://doi.org/10.1073/pnas.1422997112

Doan, N. T. Q., Paulsen, E. S., Sehgal, P., Møller, J. V., Nissen, P., Denmeade, S. R., Isaacs, J. T., Dionne, C. A. & Christensen, S. B. (2015). Targeting thapsigargin towards tumors. Steroids, 97, 2-7. https://doi.org/10.1016/j.steroids.2014.07.009

Azouaoui, H., Montigny, C., Ash, M.-R., Fijalkowski, F., Jacquot, A., Grønberg, C., López-Marqués, R. L., Palmgren, M. G., Garrigos, M., le Maire, M., Decottignies, P., Gourdon, P., Nissen, P., Champeil, P. & Lenoir, G. (2014). A high-yield co-expression system for the purification of an intact drs2p-cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate. PLoS One, 9(11), Article e112176. https://doi.org/10.1371/journal.pone.0112176

Malinauskaite, L., Quick, M., Reinhard, L., Lyons, J. A., Yano, H., Javitch, J. A. & Nissen, P. (2014). A mechanism for intracellular release of Na(+) by neurotransmitter/sodium symporters. Nature Structural and Molecular Biology, 21(11), 1006-1012. https://doi.org/10.1038/nsmb.2894

Drachmann, N. D., Olesen, C., Møller, J. V., Guo, Z., Bublitz, M. & Nissen, P. (2014). Comparing crystal structures of Ca²⁺-ATPase in the presence of different lipids. FEBS journal, 281(18), 4249-4262. https://doi.org/10.1111/febs.12957

Displaying results 157 to 168 out of 313

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Revised 13.11.2025

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Helene Eriksen