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Department of Molecular Biology and Genetics

Neurobiology

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.

Groups at DANDRITE encompass ambitious research programs that include:

Molecular and cellular mechanisms of memory
Effort-based decision making
Neuronal development and stem cells
Motor control
Brain processing of vision
Neurological and neurodegenerative diseases
Psychiatric disorders
Neurotrophic receptors, sorting
Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

List of staff and students in the research group

Group leaders

Professors

Associate Professors

Tenure Track Assistant Professor

Gilles Claude Vanwalleghem

Professor

Associate Professors

Tenure Track Assistant Professor

Peer-reviewed publications

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Azizan, E. A. B., Poulsen, H., Tuluc, P., Zhou, J., Clausen, M., Lieb, A., Maniero, C., Garg, S., Bochukova, E. G., Zhao, W., Shaikh, L. H., Brighton, C. A., Teo, A. E. D., Davenport, A. P., Dekkers, T., Tops, B., Küsters, B., Ceral, J., Yeo, G. S. H. ... Brown, M. J. (2013). Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. Nature Genetics, 45(9), 1055-1060. https://doi.org/10.1038/ng.2716

Tidow, H. & Nissen, P. (2013). Structural diversity of calmodulin binding to its target sites. FEBS journal, 280(21), 5551–5565. https://doi.org/10.1111/febs.12296

Paulsen, P. A., Jurkowski, W., Apostolov, R., Lindahl, E., Nissen, P. & Poulsen, H. (2013). The C-terminal cavity of the Na,K-ATPase analyzed by docking and electrophysiology. Molecular Membrane Biology, 30(2), 195-205. https://doi.org/10.3109/09687688.2012.713520

Al-Saaidi, R., Rasmussen, T. B., Palmfeldt, J., Nissen, P. H., Beqqali, A., Hansen, J., Pinto, Y. M., Boesen, T., Bross, P. & Mogensen, J. (2013). The LMNA mutation p.Arg321Ter associated with dilated cardiomyopathy leads to reduced expression and a skewed ratio of lamin A and lamin C proteins. Experimental Cell Research, 319(19), 3010–3019. https://doi.org/10.1016/j.yexcr.2013.08.024

Winther, A.-M. L., Bublitz, M., Karlsen, J. L., Møller, J. V., Hansen, J. B., Nissen, P. & Buch-Pedersen, M. J. (2013). The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm. Nature, 495(7440), 265-269. https://doi.org/10.1038/nature11900

Paulsen, E. S., Villadsen, J., Tenori, E., Liu, H., Bonde, D. F., Lie, M. A., Bublitz, M., Olesen, C., Autzen, H. E., Dach, I., Sehgal, P., Nissen, P., Møller, J. V., Schiøtt, B. & Christensen, SB. (2013). Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase. Journal of Medicinal Chemistry, 56(9), 3609-3619. https://doi.org/10.1021/jm4001083

Tidow, H., Poulsen, L. R., Andreeva, A., Knudsen, M., Hein, K. L., Wiuf, C., Palmgren, M. G. & Nissen, P. (2012). A bimodular mechanism of calcium control in eukaryotes. Nature, 491, 468-472. https://doi.org/10.1038/nature11539

Dach, I., Olesen, C., Signor, L., Nissen, P., le Maire, M., Møller, J. V. & Ebel, C. (2012). Active Detergent-solubilized H⁺,K⁺-ATPase Is a Monomer. Journal of Biological Chemistry, 287, 41963-41978. https://doi.org/10.1074/jbc.M112.398768

Nissen, P. (2012). A POTluck of peptide transporters. E M B O Journal, 31(16), 3382-3383. https://doi.org/10.1038/emboj.2012.206

Denmeade, S. R., Mhaka, A. M., Rosen, D. M., Brennen, W. N., Dalrymple, S., Dach, I., Olesen, C., Gurel, B., Demarzo, A. M., Wilding, G., Carducci, M. A., Dionne, C. A., Møller, J. V., Nissen, P., Christensen, S. B. & Isaacs, J. T. (2012). Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy. Science Translational Medicine, 4(140), 140ra86. https://doi.org/10.1126/scitranslmed.3003886

Thøgersen, L. & Nissen, P. (2012). Flexible P-type ATPases interacting with the membrane. Current Opinion in Structural Biology, 22(4), 491-499. https://doi.org/10.1016/j.sbi.2012.05.009

Poulsen, H., Nissen, P., Mouritsen, O. G. & Khandelia, H. (2012). Protein kinase A (PKA) phosphorylation of Na+/K+-ATPase opens intracellular C-terminal water pathway leading to third Na+-binding site in molecular dynamics simulations. Journal of Biological Chemistry, 287(19), 15959-15965. https://doi.org/10.1074/jbc.M112.340406

Displaying results 193 to 204 out of 312

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Revised 13.11.2025

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Helene Eriksen