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40 Years of Biostructural Chemistry

  • Friday 21 March 2014
  • Aarhus University, Denmark

In 1974, Professor Clark came to Aarhus to form the Biostructural Chemistry Division of the Department of Chemistry. In the following years, he greatly expanded the research activities, and after starting the first protein crystallography group in Denmark he recruited two crystallographers, Troels la Cour and Jens Nyborg, to strengthen protein structure and function research. The cell and molecular biology research in the group was strongly established by the employment of Julio Celis and Roger Garrett. In 1996, the Biostructural Chemistry Division, consisting now of about 50 people, merged with the Department of Molecular Biology.

Today the group - now called Structural Biology - is the largest group of the department with 94 staff and students (34 scientific staff, 16 technical and administrative staff, 32 PhD students and 12 MSc students), and the research group has eight group leaders covering the following areas: structure determination of large macromolecules and macromolecular complexes; membrane proteins; RNA metabolism and decay; the protein synthesis; cellular receptors and bioinformatics; virus infection and innate immunity; macromolecular interactions of translation elongation factors; structural studies of the ribosomal regulation; biological microcables, bacterial pathogenesis and neurotransmitter transport.

Programme

08:30_09:00 Registration
09:00-09:20 Welcome and introduction to keynote speaker by Professor Emeritus Brian F.C. Clark
09:20-09:30 iNANO staff and students enter to attend the keynote lecture
09:30-10:15

Keynote lecture: "The history of Biostructural Chemistry"
Sterling Professor Emeritus Peter Moore, Yale University, Department of Chemistry
10:15-10:45 Coffee break

STRUCTURE-FUNCTION STUDIES OF PROTEIN BIOSYNTHESIS

10:45-10:55 Introduction by Chairman, Professor Gregers Rom Andersen
10:55-11:20

Professor Daniela Rhodes, School of Biological Sciences, Nanyang Technological University, Singapore: From tRNA to Telomerase
11:20-11:45

Professor William C. Merrick, Case Western Reserve University, Biochemistry Department, USA: Celebration of 40 years of structural biology: As seen mostly through the eyes of a translationalist

11:45-12:10

Professor Jan Barciszewski, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland: Catalytic RNAs for all occasions
12:10-12:35 Professor Stephen Douthwaite, University of Southern Denmark, Department of Biochemistry and Molecular Biology: Eukaryotes for manipulating the genomes of intractable prokaryotes
12:35-12:45 Group photo of all participants
12:45-13:35 Lunch

STRUCTURAL BIOLOGY

13:35-13:45 Introduction by chairman, Associate Professor Søren Thirup
13:45-14:05

Postdoctoral Scholar Bjørn Panyella Pedersen, University of California, San Francisco, School of Medicine: Phosphate Uptake: Insights from Structural Biology
14:05-14:25

Associate professor Bente Vestergaard, Dept. Drug Design and Pharmacology, Copenhagen University: Structural investigations of the protein fibrillation process, using small angle x-ray scattering as the central tool
14:25-14:45 Associate professor René Jørgensen, Statens Serum Institut, Copenhagen: Hunting for unknown virulence factors in Clostridium difficile
14:45-15:05 EMBL group leader Jens Preben Morth, Centre for Molecular Medicine Norway, Oslo, Norway: Characterization of supramolecular Tankyrase complexes implicated in colorectal cancer, using an intrinsically disordered protein as bait
15:05-15:30 Coffee

CELL BIOLOGY, CANCER AND AGEING

15:30-15:40 Introduction by chairman, Associate Professor Suresh Rattan
15:40-16:05

Associate Scientific Director Julio Celis, the Danish Cancer Society Research Center, Copenhagen, Denmark: A personal account of the early stages of proteomics at Aarhus University
16:05-16:30

Dr. Helle Færk Jørgensen, lecturer in stem cell biology, Department of Medicine, University of Cambridge, UK: Chromatin regulation and cell plasticity
16:30-16:55 Professor Richard Faragher, University of Brighton, School of Pharmacy and Biomolecular Sciences, UK: 40 years of progress: biological chemistry, cellular senescence and organismal ageing
16:55-17:05 Break
17:05-17:30 Professor Poul Nissen, Department of Molecular Biology, Aarhus University: The end of the beginning
17:30-17:35

Introduction to keynote speaker by Professor Poul Nissen, Department of Molecular Biology, Aarhus University
17:35-18:20

Keynote lecture: Professor Venki Ramakrishnan (Nobel laureate, Chemistry 2009), MRC Laboratory of Molecular Biology, Cambridge

19:00

Dinner at the Department of Chemistry

Practical information

Time: Friday 21 March 2014 at 8:30-18:30 - dinner at 19:00

Location: Aarhus University, the auditorium of the iNANO building, Gustav Wieds Vej 14, 8000 Aarhus C

Dinner: Aarhus University, the Canteen of the Department of Chemistry

Participants: national and international friends of the Structural Biology Group at Aarhus University

Deadline for registration: Monday 17 March 2014

Group photo of participants

Download the group photo that was taken during the 40th Anniversary meeting (right-click on the photo, save image as ....)

Photos from the 1980's

Download the PDF-file with photos with mostly students from the group

The photos are taken at Brian Clark's home at Risskov in the 80's.

Anniversary booklet

Download the PDF-file with the programme, list of participants and photos from the group throughout the years.

Sponsors

DanScatt