The Centre for Structural Biology consists of 9 independent but closely connected research groups at the Department of Molecular Biology and Genetics, Aarhus University, Denmark. Common to the groups is the use of x-ray crystallography to elucidate the three-dimensional structure of biological macromolecules, but the focus spans from translation factors to membrane proteins. In addition to the crystallographic analysis, a wide range of biochemical, biophysical, and analytical techniques are used at the centre.
The centre employs about 70 people, ranging from students to post docs and staff scientists and has a long tradition for housing visiting scientists from all over the world.
The centre houses facilities for all techniques needed for macromolecular structure determination, including cloning and expression of recombinant proteins in both bacteria and eukaryotic cell systems, advanced protein purification methods and biochemical analysis, as well as crystallisation and fast structure determination by x-ray crystallography via anomalous scattering methods. When applicable, other structural probing methods such as cryoelectron microscopy and small-angle scattering are used in collaboration with research teams in both Denmark and abroad.
Public dissemination of results mainly takes place through publication in international, peer-reviewed scientific journals. In addition, landmark results are communicated to the broader public through our collaboration with Dansk Naturvidenskabsformidling (Danish Science Communication), as well as in the press.