During her PhD studies, Michelle Møhlenberg researched the role of the innate immune system in inflammatory diseases. More specifically she has researched the gene IFNL4 and its functions. Michelle Møhlenberg treated an animal model of non-alcoholic fatty liver disease with protein she purified. Furthermore, she analyzed the genetics of IFNL4 in one cohort of non-alcoholic fatty liver disease patients and in a cohort of COVID-19 patients. The new research findings contribute to the understanding of how of IFNL4 is involved in different inflammatory diseases.  

The PhD study was completed at department of Molecular Biology and Genetics, Faculty of Natural Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Thursday, 28^th October 2021 at 16:00 CET.
Place: Building 1252, room 204, Lecture Theatre Eduard Biermann, Aarhus University, Bartholins Allé 3, 8000 Aarhus c 
Title of PhD thesis: A multipronged approach to characterize the functions of interferon lambda 4
Contact information: Michelle Møhlenberg, e-mail: mm@mbg.au.dk, tel.: +45 29643439

Members of the assessment committee:
Clinical Associate Professor Joan Durbin, Department of Pathology, New Jersey Medical School, USA   
Professor John McLauchlan, Centre for Virus Research, University of Glasgow, Scotland
Professor Ditlev Egeskov Brodersen (chairman), Department of Molecular Biology and Genetics, Aarhus University, Denmark

Main supervisor:
Professor Rune Hartmann, Department of Molecular Biology and Genetics, Aarhus University, Denmark

Co-supervisors:
Clinical Associate Professor Karen Louise Thomsen, Department of Hepatology and Gastroenterology, Aarhus University Hospital, Denmark    
Clinical Professor Henning Grønbæk, Department of Hepatology and Gastroenterology, Aarhus University Hospital, Denmark

Language: The PhD dissertation will be defended in English.

The defence is public. The PhD thesis is available for reading at the Graduate School of Natural Sciences/GSNS, Katrinebjergvej 89F, building 5132, 8200 Aarhus N.