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Søren Fjelstrup: Using an artificial tongue to detect cancer

PhD defence, Monday 29 June 2020, Søren Fjelstrup.

Søren Fjelstrup

During his PhD studies, Søren Fjelstrup researched characterization of complex biological samples using aptamer libraries.

The sensation of taste is produced by innumerable different chemical compounds which are recognized by taste receptors. By producing artificial receptor analogs, we can rival this wide specificity. This allows us to detect complex changes in the body, in which a single measurement is not sufficient. An example of this would be cancer. Using machine learning algorithms, it has been shown in this work that it is possible to translate the signals from millions of these receptor analogs in a way that allows detection of bladder cancer in blood and to distinguish between different beers.

The PhD study was completed at Interdisciplinary Nanoscience Center (iNANO), Faculty of Natural Sciences, Aarhus University.

This summary was prepared by the PhD student.

Time: Monday, 29 June 2020 at 13.15
Place: Building 1593, Room 012, iNANO Auditorium, Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C.
The PhD defence will be held online. To receive a link to the event, please send an e-mail to Ken Howard, kenh@inano.au.dk, chairman.
Title of PhD thesis: Aptamer Fishing in Complex Sequence Pools
Contact information: Søren Fjelstrup, e-mail: soeren.fjelstrup@inano.au.dk, tlf.: +45 29911601
Members of the assessment committee:
Associate Professor Casey Greene, Department of Pharmacology, University of Pennsylvania, USA
Professor Jan Gorodkin, Department of Veterinary and Animal Sciences, University of Copenhagen, Denmark
Associate Professor Ken Howard, iNANO, Aarhus University (chair)
Main supervisor:
Professor Jørgen Kjems, iNANO and Department of Molecular Biology and Genetics, Aarhus University
Language: The PhD dissertation will be defended in English

The defence is public.

Due to the coronavirus situation, Aarhus University is physically closed. Therefore, the PhD thesis will not be available for reading at the offices of the PhD administration. Instead, interested parties may send an e-mail to gradschool.nat@au.dk, and receive a digital copy of the PhD thesis. Please note, it may in certain cases be necessary to make an individual arrangement to read the PhD thesis.