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Ebbe S. Andersen receives 10 mio from the Novo Nordisk Foundation (Photo: Lars Kruse, AU Photo)
Researchers from the Andersen Lab for Biomolecular Design who developed the RNA-based technology platform (Photo: Nestor Sampedro)
Illustration of (A) RNA origami scaffolds that can be produced in cells, (B) RNA scaffolds for enzymatic cascades, (C) Function of RNA scaffolds and sensors in cells. (Ill.: Ebbe S. Andersen)

2020.07.03 | Grant

DKK 10 million for developing nanoscale assembly lines for biotechnological production

Ebbe S. Andersen is awarded a DKK 10 million Ascending Investigator Grant from the Novo Nordisk Foundation’s Research Leader Programme. The research project aims at using recently developed RNA nanotechnology-based assembly lines, sensors and nanorobots to improve biochemical reactions inside cells. The potential outcome will be improved bacterial…

Jørgen Kjems (left) og Morten T. Venø describes in an article in PNAS, how expression of non-coding RNA changes during epileptic seizures in rodents (Photo: Anne Færch Nielsen)

2020.06.25 | Research, Knowledge exchange

Large-scale data sets identify small RNAs with a role in epilepsy

A new paper from Jørgen Kjems' group at iNANO and MBG describes how expression of non-coding RNA changes during epileptic seizures in rodents. The authors found that inhibiting a specific set of microRNAs (miRNAs) by antisense technology reduced seizure frequency in a mouse model, suggesting that these RNA molecules could serve as possible targets…

Joseph A. Lyons receives DKK 10 million from Lundbeckfonden to study lipid transport (photo: Lisbeth Heilesen)

2020.06.16 | Grant

Joseph Lyons receives DKK 10 million from Lundbeckfonden to study cell membranes

Joseph Lyons is one of the nine talented researchers who will become a Lundbeckfonden fellow in 2020. And the grant that comes with the appointment enables him to establish his own research group and devote himself to research for the next five years at the Department of Molecular Biology and Genetics/DANDRITE, Aarhus University.

Together with researchers from The Crick Institute in the UK, Hans Henrik Gad (left) and Rune Hartmann have published results in Science describing how an immune response prevents the rebuilding of damaged lung tissue after infection with viruses such as influenza and SARS-CoV-2. Photo: Lisbeth Heilesen

2020.06.11 | Research

Signal substance that can potentially be used to treat COVID-19 also has negative effects

It is difficult wage war without causing collateral damage , and the same goes for our immune system when it has to fight viral infections, such as influenza and COVID-19. Research by a team from The Crick Institute and Aarhus University describes how an immune response prevents the rebuilding of damaged lung tissue after infection with viruses…

A project team from Aarhus University and Fida Biosystems will use advanced microfluidic techniques in the search for compounds, which can block the contact between SARS-CoV-2 virus and receptors on human cells. Click on the graphic to see it full size (Graphics by Daniel Otzen)
Daniel Otzen is heading a collaborative project with DKK 3.8 million from the Innovation Fund Denmark for combating COVID-19. Photo: Jesper Rais, AU.

2020.06.02 | Grant

Newly established cooperation receives funding to combat COVID-19

Daniel Otzen and collaborators, Jørgen Kjems and Victoria Birkedal from the Interdisciplinary Nanoscience Center (iNANO) and the company Fida Biosystems, have received DKK 3.8 million from the Innovation Fund Denmark to develop a screening system to identify drugs that are able to combat COVID-19.

2020.05.18 | Grant

Increased funding for research into the mechanisms of cholesterol uptake

With a grant of DKK 6,181,260 (USD 900,000) from the Independent Research Fund Denmark, Associate Professor Bjørn Panyella Pedersen can now increase his research efforts to gain a better understanding of the mechanisms behind cholesterol uptake.

2020.05.18 | Grant

More than DKK 23 million (USD 3.3 million) to researchers from MBG from the Independent Research Fund Denmark

The Independent Research Fund Denmark (DFF) - Nature and Universe - grants DKK 23.4 million to seven researchers at the Department of Molecular Biology and Genetics.

“An intravital microscopy image depicting blood vessels, macrophages and nanoparticles. Interested in how they move in real-time? See the movie featured at the end of this article (image: Yuya Hayashi)
Zebrafish embryos as an emerging research model for in vivo imaging and screening of nanomaterials. Transgenic lines with a cell type-specific fluorescent protein reporter allow us to study the dynamic behaviour of e.g. macrophages and how injected nanomaterials are cleared from the bloodstream in a living organism. Transmission electron microscopy approaches can then complement the real-time observations by visualising those processes at the nanoscale. Both imaging approaches are available at Aarhus University. (Image: Yuya Hayashi. Adapted from Hayashi et al. (2020) ACS Nano. Copyright 2020 American Chemical Society)

2020.05.13 | Research

Zebrafish let you see the biological fate of nanoparticles in vivo

Ever wondered if you could see through the body of a living organism and observe the dynamic interplay between cells and nanoparticles injected into the bloodstream? This is now possible as the use of transgenic zebrafish embryos now offers a unique opportunity for intravital microscopy at imaging resolutions unrivalled by existing mammalian…

Thibaud Dieudonné awarded the PhD thesis prize 2020 from the French Biophysical Society (photo: Lisbeth Heilesen)

2020.05.07 | Awards

Thibaud Dieudonné awarded the PhD thesis prize 2020 from the French Biophysical Society

Thibaud Dieudonné, who is currently postdoc in Poul Nissen’s research group, was awarded the prize for his PhD thesis entitled “Functional and Structural characterization of lipid flippases: the yeast Drs2p/Cdc50p and the disease-related human ATP8B1/CDC50A complexes”.

Christian Bendixen (photo: Ida Marie Jensen, AU Photo)

2020.04.29 | People

Obituary for Professor Christian Bendixen

With Professor Christian Bendixen's untimely death, the Department of Molecular Biology and Genetics has lost an excellent researcher and a good colleague. Christian Bendixen died suddenly from a blood clot at the age of 57. We are all deeply affected.

Professor Jørgen Kjems and collaborators receive fundings from Independent Research Fund Denmark for corona related research. Photo: Jesper Rais, AU Photo

2020.04.27 | Grant

Fundings for prediction of COVID-19 infection and clinical severity

One of the major challenges of reopening the community, during the ongoing COVID-19 pandemic, is having access to a rapid and reliable test for SARSCoV2 infection. With fundings from Independent Research Fund Denmark Professor Jørgen Kjems will, in collaboration with researchers from DTU and Rigshospitalet, develop a method that can detect the…

Ernst-Martin Füchtbauer

2020.04.15 | People

Ernst-Martin Füchtbauer elected President of the International Society for Transgenic Technology

In March, Ernst-Martin Füchtbauer was elected president of the largest international society for people working with genetically modified animals, namely the International Society for Transgenic Technology (ISTT).

AU researchers collaborate with international research team on improving the efficiency of bioelectrical systems. (Graphics: Copyright © 2020, Nature Research).

2020.03.30 | Research

Enhanced microbes as alternative green energy sources

The demand for energy is growing and so is the demand for alternative energy solutions, which includes living sources of electricity. In collaboration with an international team, Thomas Boesen and his iNANO colleagues have created microbial energy cells and shows a method for improving the efficiency of bioelectrical systems.

The three recipients of the Marie Sklodowska-Curie Individual fellowship (from left): Narcis Petriman, Ronja Driller and Jan Heiner Driller. Photo: Lisbeth Heilesen

2020.03.25 | Grant

Three molecular biologists receive the prestigious Marie Sklodowska-Curie fellowship

Narcis Adrian Petriman, Ronja Driller and Jan Heiner Driller from the Department of Molecular Biology and Genetics at Aarhus University receive the highly prestigious Marie Sklodowska-Curie Individual Fellowship. It is the first time that the Department obtains three fellowships in one application round.

Fly Copulation. Credit: Philipsborn Research group
Graphical abstract: During copulation, males transfer not only sperm, but also seminal fluid. The authors hypothesize: Specific components of the male accessory gland secondary cells - secondary cell products (SCPs) cause the female to start singing. Her singing in turn prompts the male to allocate his ejaculate differently, ultimately giving him a reproductive advantage over other males, by biasing the female to mate with the next male later. Credit: Peter Kerwin, PhD-student, Philipsborn group

2020.03.20 | Research

Female fruit flies sing by pulsed wing vibrations while copulating

The discovery of a female-specific acoustic behavior sheds new light on Drosophila mating, sexual dimorphisms of neuronal circuits and the impact of seminal fluid molecules on nervous system and behavior.

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