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AU researchers collaborate with international research team on improving the efficiency of bioelectrical systems. (Graphics: Copyright © 2020, Nature Research).

2020.03.30 | Research

Enhanced microbes as alternative green energy sources

The demand for energy is growing and so is the demand for alternative energy solutions, which includes living sources of electricity. In collaboration with an international team, Thomas Boesen and his iNANO colleagues have created microbial energy cells and shows a method for improving the efficiency of bioelectrical systems.

The three recipients of the Marie Sklodowska-Curie Individual fellowship (from left): Narcis Petriman, Ronja Driller and Jan Heiner Driller. Photo: Lisbeth Heilesen

2020.03.25 | Grant

Three molecular biologists receive the prestigious Marie Sklodowska-Curie fellowship

Narcis Adrian Petriman, Ronja Driller and Jan Heiner Driller from the Department of Molecular Biology and Genetics at Aarhus University receive the highly prestigious Marie Sklodowska-Curie Individual Fellowship. It is the first time that the Department obtains three fellowships in one application round.

Fly Copulation. Credit: Philipsborn Research group
Graphical abstract: During copulation, males transfer not only sperm, but also seminal fluid. The authors hypothesize: Specific components of the male accessory gland secondary cells - secondary cell products (SCPs) cause the female to start singing. Her singing in turn prompts the male to allocate his ejaculate differently, ultimately giving him a reproductive advantage over other males, by biasing the female to mate with the next male later. Credit: Peter Kerwin, PhD-student, Philipsborn group

2020.03.20 | Research

Female fruit flies sing by pulsed wing vibrations while copulating

The discovery of a female-specific acoustic behavior sheds new light on Drosophila mating, sexual dimorphisms of neuronal circuits and the impact of seminal fluid molecules on nervous system and behavior.

Professor Jørgen Kjems leads the group of AU researchers participating in the project. Photo: Peter F. Gammelby

2020.03.19 | Grant

AU steps up the virus research with millions from the Carlsberg Foundation

Professor Jørgen Kjems from MBG and iNANO will collaborate with researchers from Health, the University of Copenhagen and the Danish Serum Institute, and with DKK 25 millions from the Carlsberg Foundation they will develop methods for diagnosis, treatment and prevention of SARS-CoV-2 infections. The goal is at the same time to equip the world to…

Professor Jørgen Kjems participated in the development of the ODIN-concept. Photo: Peter F. Gammelby, AU
Marie Louise Conradsen has tentatively started a tour of departments at the three faculties to recruit researchers to the project. Photo: AU

2020.03.13 | Grant

ODIN invites researchers from Natural Sciences to open innovation with pharmaceutical companies

Aarhus University and a number of Danish and international drug manufacturers are working together in ground-breaking, open research collaboration, ODIN, which the Novo Nordisk Foundation is supporting with DKK 54.5 million (EUR 7.2 million). The project involves scientists from the three faculties Nat, Tech and Health, and data and results from…

The first three-dimensional structures of the IgE antibody triggering allergic reactions. To the left is shown the experimental data obtained with electron microscopy that were combined to yield the three dimensional structure of IgE itself. To the right is depicted the experimental data and the resulting three dimensional structure for IgE bound to a fragment of the drug candidate Ligelizumab. Figure: Rasmus Kjeldsen Jensen, AU

2020.02.24 | Research

Electron microscopy allows scientists to understand the molecular trigger of allergic reactions

An international research team has been able to describe the overall structure of the antibody type IgE, which is the key molecule in allergic diseases. This is a scientific breakthrough which provides important insights into basic mechanisms of allergic reactions and may pave the way for more effective allergy medicine. The new research results…

Nuclear transcripts without poly(A)-tagged 3’ends (‘pA-‘) are normally targeted to the RNA exosome via the cofactor NEXT (left), whereas transcripts with a poly(A) tail (‘pA+’) are targeted via PAXT (right). If NEXT-dependent decay fails, target RNAs acquire a poly(A)-tail and are handed to the exosome by PAXT. Such two-layered targeting ensures the robust decay of potentially hazardous RNAs. Figure: Guifen Wu and Manfred Schmid.

2020.02.19 | Research

How to keep the nucleus clean

RNA turnover in the nuclei of eukaryotic cells is controlled by the RNA exosome aided by numerous cofactors. Researchers at Aarhus University and Copenhagen University now show how two major nuclear exosome cofactors recognize their RNA targets to keep a clean nuclear environment. This is important for the health of our cells – and thus humans.

Results published by AU researchers reveal that surfactant-mediated unfolding and refolding of proteins are complex processes with several structures present, and rearrangements occur on time scales from sub-milliseconds to minutes. (Image: Reproduced with permission from the Royal Society of Chemistry).

2020.02.17 | Research

Caught soap-handed: Understanding how soap molecules help proteins get in and out of shape

Controlling protein structure is crucial in the production of detergents and cosmetics. Up to now we have not had a clear understanding of how soap molecules and proteins work together to change protein structure. Now AU researchers have succeeded in creating a detailed picture of both unfolding and refolding of a protein by soap molecules on the…

The recipients of the Young Investigator grant 2020 from VILLUM FONDEN. Dennis Kjølhede Jeppesen is number seven from the right. Photo: VILLUM FONDEN/Thomas Frandsen
Dennis Kjølhede Jeppesen (photo: private)

2020.01.24 | Grant

Dennis Kjølhede Jeppesen receives Young Investigator grant from VILLUM FONDEN

Every year, the VILLUM FONDEN supports research talent with the ambition to create their own independent research profiles, and this will now be possible for Dennis K. Jeppesen who – with a five-year grant of DKK 10 million – can return from the US to set up his own research group at the Department of Molecular Biology and Genetics, Aarhus…

<em>Lotus japonicus</em>. Photo: Niels Sandal, Aarhus University

2020.01.14 | Research

Plant genomes reveal the basis for adaptation to contrasting climates

In the face of rapid climate change, it is important that plants can adapt quickly to new conditions to ensure their survival. Using field experiments and plant genome studies, an international research team has pinpointed areas of the genome that are affected during local adaptation to contrasting climates. This new insight into local adaptation…

photo: Colourbox

2019.12.19 | Grant

Wild plants as climate change-resistant crops

Together with colleagues from the University of Copenhagen, researchers from Aarhus University will make new crops out of wild plants. Climate changes and an increasing population make it imperative to find alternatives to the crops that feed the world population today. The Novo Nordisk Foundation has given DKK 60 million to the research project…

In the future, the newly discovered mechanism will potentially enable insertion of the sensor specifically into diseased cells and may allow diagnosis at the single cell level. Figure: Rasmus Peter Thomsen/AU.
The researchers from Aarhus University behind the scientific article (from left): Rasmus P. Thomsen, Jørgen Kjems and Rasmus Schøler Sørensen. Photo: Anne Færch Nielsen/AU.

2019.12.13 | Research

Researchers create synthetic nanopores made from DNA

A scientific collaboration led by researchers at iNANO/Department of Molecular Biology and Genetics at Aarhus University and the Department of Chemistry at the University of Copenhagen has resulted in the construction of a synthetic DNA nanopore capable of selectively translocating protein-size macromolecules across lipid bilayers.

Poul Nissen receives DKK 40 million (USD 6 million) from the Lundbeck Foundation's professor programme to conduct ground-breaking brain research. Photo: Lisbeth Heilesen

2019.12.10 | Grant

Poul Nissen receives the Lundbeck Foundation's professor grant

The Lundbeck Foundation is awarding grants worth DKK 232 million (USD 34 million) to six leading neuroscientists. The LF Professorships programme is the Foundation’s largest grant allocation to date.

Bjørn Panyella Pedersen

2019.11.26 | Grant

Understanding how cholesterol enters the cell

Uptake of cholesterol needs to be tightly controlled, and too much cholesterol can lead to cardiovascular disease and other maladies. With a grant of DKK 4.5 mio from the Carlsberg Foundation, Bjørn Panyella Pedersen from the Department of Molecular Biology and Genetics, Aarhus University, will aim at uncovering parts of this essential process.…

With a grant from the Independent Research Fund Denmark’s Sapere Aude programme, Peter Refsing Andersen from the Department of Molecular Biology and Genetics and AIAS, Aarhus University, will uncover the strategies used by DNA parasites to evade the genomic defence mechanisms. Photo: Lisbeth Heilesen

2019.11.19 | Grant

Revealing how genes fight each other for space in the genome

Spread of DNA parasites can destroy important genes, so all forms of life have evolved genome defence mechanisms to keep the parasites in check. With a grant of DKK 6.2 mio. from the Independent Research Fund Denmark’s Sapere Aude programme, Peter Refsing Andersen from the Department of Molecular Biology and Genetics and AIAS, Aarhus University,…

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