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Latest peer-reviewed publications at MBG

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Displaying results 151 to 62 out of 62

Peer-reviewed publications at MBG - all years

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Grove, J., Børglum, A. D., Baron-Cohen, S., APEX consortium & Mortensen, P. B. (2025). Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population. Molecular Psychiatry, 30(8), 3393-3403. Article 2301. https://doi.org/10.1038/s41380-025-02927-z

Dubiez, E., Garland, W., Finderup Brask, M., Boeri Erba, E., Heick Jensen, T., Kadlec, J. & Cusack, S. (2025). Structural basis for the synergistic assembly of the snRNA export complex. Nature Structural and Molecular Biology, 32(8), 1555-1566. https://doi.org/10.1038/s41594-025-01595-5

Ung, K. L., Schulz, L., Zuzic, L., Amsinck, B. L., Koutnik-Abele, S., Benhammouche, I., Andersen, C. G., Nel, L., Schiøtt, B., Stokes, D. L., Hammes, U. Z. & Pedersen, B. P. (2025). Structures and mechanism of the AUX/LAX transporters involved in auxin import. Nature Plants, 11(8), 1670-1680. https://doi.org/10.1038/s41477-025-02056-z

Tang, A. A., Gobry, M. V., Li, S., Andersen, E. S. & Franco, E. (2025). Switchable RNA motifs for dynamic transcriptional control of RNA condensates. Nucleic Acids Research, 53(12), Article gkaf497. https://doi.org/10.1093/nar/gkaf497

Mitchell, C. W., Yuan, H., Sønderstrup-Jensen, M., Ferenbach, A. T. & van Aalten, D. M. F. (2025). O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control. Open Biology, 15(7), Article 250064. https://doi.org/10.1098/rsob.250064

Jiang, Y., Wang, D., Zeng, S., Zhang, Y., Jiang, L., Pourmirzaei, M., Manshour, N., Esmaili, F., Zhang, W., Møller, I. M. & Xu, D. (2025). MULoc-target: Targeting peptide classification and detection using a protein language model. Briefings in bioinformatics, 26(4), Article bbaf436. https://doi.org/10.1093/bib/bbaf436

Nowak, J. S., Olesen, S., Tian, P., Bærentsen, R. L., Brodersen, D. E. & Otzen, D. E. (2025). Role of electrostatics in cold adaptation: A comparative study of eury- and stenopsychrophilic triose phosphate isomerase. Biochimica et Biophysica Acta - Proteins and Proteomics, 1873(4), Article 141072. https://doi.org/10.1016/j.bbapap.2025.141072

Thomsen, M. E., Bennike, T. B., Christiansen, G., Emmersen, J., Laursen, N. S., Zarantonello, A., Andersen, G. R., Liu, L., Dueholm, M. K. D., Opstrup, K. V., Stensballe, A. & Birkelund, S. (2025). Differences in complement activation of serum-resistant and serum-sensitive Klebsiella pneumoniae isolates. Molecular immunology, 183, 274-285. https://doi.org/10.1016/j.molimm.2025.05.014

Olsen, W. P., Larsen, A.-K. K., Christensen, J. L., Malle, M. G. & Otzen, D. E. (2025). Investigating strategies for creating cross-linked amyloid fibril networks through branching of amyloid growth. Colloids and surfaces. B, Biointerfaces, 251, 114617. Article 114617. https://doi.org/10.1016/j.colsurfb.2025.114617

Henches, L., Kim, J., Yang, Z., Rubinacci, S., Pires, G., Albiñana, C., Boetto, C., Julienne, H., Frouin, A., Auvergne, A., Suzuki, Y., Djebali, S., Delaneau, O., Ganna, A., Vilhjálmsson, B., Privé, F. & Aschard, H. (2025). Polygenic risk score prediction accuracy convergence. Human Genetics and Genomics Advances, 6(3), Article 100457. https://doi.org/10.1016/j.xhgg.2025.100457

Fabbrizio, P., Baindoor, S., Margotta, C., Su, J., Morrissey, E. P., Woods, I., Hogg, M. C., Vianello, S., Venø, M. T., Kjems, J., Sorarù, G., Bendotti, C., Prehn, J. H. M. & Nardo, G. (2025). Protective role of Angiogenin in muscle regeneration in amyotrophic lateral sclerosis: Diagnostic and therapeutic implications. Brain Pathology, 35(4), Article e13328. https://doi.org/10.1111/bpa.13328

Zhang, C., Reid, K., Schierup, M. H., Wang, H., Candolin, U. & Merilä, J. (2025). Rate of de novo mutations in the three-spined stickleback. Heredity, 134(7), 387-395. https://doi.org/10.1038/s41437-025-00767-9

Kefalopoulou, S., Rullens, P. M. J., de Luca, K. L., de Vries, S. S., Korthout, T., van Oudenaarden, A., Zeller, P. & Kind, J. (2025). Retrospective and multifactorial single-cell profiling reveals sequential chromatin reorganization during X inactivation. Nature Cell Biology, 27(7), 1186-1198. https://doi.org/10.1038/s41556-025-01687-w

Kristoffersen, E. L., McRae, E. K. S., Sørensen, N. R., Holliger, P. & Andersen, E. S. (2025). Roles of dimeric intermediates in RNA-catalyzed rolling circle synthesis. Nucleic Acids Research, 53(11), Article gkaf057. https://doi.org/10.1093/nar/gkaf057

Almeida, A. V., Jensen, K. T., Harwood, S. L., Jørgensen, M. H., Nielsen, N. S., Thøgersen, I. B., Enghild, J. J. & Andersen, G. R. (2025). Three cryo-EM structures of CD109 reveal its mechanism of protease inhibition. Cell Reports, 44(6), Article 115787. https://doi.org/10.1016/j.celrep.2025.115787

Jin, Z., Olsen, W. P., Mörman, C., Leppert, A., Kumar, R., Møllebjerg, A., Nielsen, L. G., Moshynets, O. V., Frasinyuk, M. S., Elosua, J. Y., Ferreira, D., Abelein, A., Landreh, M., Knight, S. D., Johansson, J., Otzen, D. E. & Chen, G. (2025). Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor. Science Advances, 11(24), Article eads7525. https://doi.org/10.1126/sciadv.ads7525

Behrens, T., Balasubramanian, J., Ivask, M., Nõmm, M., Kavak, A., Secher, J. B.-M., Kadarmideen, H. N. & Rabaglino, M. B. (2025). In vitro processes alter the embryonic disc epigenome and transcriptome in the pre-implantation elongated bovine embryo. Biology of Reproduction, Article ioaf095. Advance online publication. https://doi.org/10.1093/biolre/ioaf095

Garcia-Erill, G., Liu, S., Le, M. D., Hurley, M. M., Nguyen, H. D., Nguyen, D. Q., Nguyen, D. H., Santander, C. G., Sánchez Barreiro, F., Gomes Martins, N. F., Hanghøj, K., Salleh, F. M., Ramos-Madrigal, J., Wang, X., Sinding, M. H. S., Morales, H. E., Stæger, F. F., Wilkinson, N., Meng, G. ... Heller, R. (2025). Genomes of critically endangered saola are shaped by population structure and purging. Cell, 188(12), 3102-3116.e22. https://doi.org/10.1016/j.cell.2025.03.040

Paasch, T. P., Olesen, M. T. J., García-Rodríguez, J. L., Assmus, A. M., Fenton, R. A., Kjems, J., Hager, H. & Kristensen, L. S. (2025). ciRS-7 expression is epigenetically regulated in cancer cells across human adenocarcinomas. PLoS Genetics, 21(6), Article e1011726. https://doi.org/10.1371/journal.pgen.1011726

Nielsen, J., Pedersen, J. N., Kleijwegt, G., Nowak, J. S., Nami, F., Johansen, C., Sassetti, E., Berg, B. B., Lyngsø, N. M., Brøchner, B. H., Holm Carlson, J., Simonsen, A. J., Pallisgaard Olsen, W., Simonsen, B. W., Mikkelsen, J. H., Sereika-Bejder, V., Lauritsen, J. A., Merrild, K. F., Malle, M. G. ... Otzen, D. E. (2025). Nanobodies raised against the cytotoxic α-synuclein oligomer are oligomer-specific and promote its cellular uptake. npj biosensing, 2, Article 23. https://doi.org/10.1038/s44328-025-00042-1

Herring, P., Roedgaard, M., Holst, C. M., Christensen, H., Knudsen, B. R., Bjergbaek, L. & Andersen, A. H. (2025). A cellular system to study responses to a collision between the transcription complex and a protein-bound nick in the DNA template. FEBS Letters, 599(12), 1749-1759. https://doi.org/10.1002/1873-3468.70053

Schumacher, J. D., Dusek, N., Mendoza-Suárez, M. & Geddes, B. A. (2025). Adaptation of Plasmid-ID Technology for Evaluation of N₂-Fixing Effectiveness and Competitiveness for Root Nodulation in the Sinorhizobium–Medicago System. Environmental Microbiology, 27(6), Article e70118. https://doi.org/10.1111/1462-2920.70118

Horsdal, H. T., Albiñana, C., Zhu, Z., Boelt, S. G., Borbye-Lorenzen, N., Cohen, A. S., Skogstrand, K., Melgaard, L., MacSween, N. J., Thorbek, M. J., Plana-Ripoll, O., Petersen, L. V., Bulik, C. M., Børglum, A. D., Mors, O., Nordentoft, M., Werge, T., Moen, G.-H., D'Urso, S. ... McGrath, J. J. (2025). Convergent evidence linking neonatal vitamin D status and risk of neurodevelopmental disorders: a Danish case-cohort study. The Lancet Psychiatry, 12(6), 410-420. https://doi.org/10.1016/S2215-0366(25)00099-9

Bontempi, D., Zalay, O., Bitterman, D. S., Birkbak, N., Shyr, D., Haugg, F., Qian, J. M., Roberts, H., Perni, S., Prudente, V., Pai, S., Dekker, A., Haibe-Kains, B., Guthier, C., Balboni, T., Warren, L., Krishan, M., Kann, B. H., Swanton, C. ... Aerts, H. J. W. L. (2025). FaceAge, a deep learning system to estimate biological age from face photographs to improve prognostication: a model development and validation study. The Lancet Digital Health, 7(6), Article 100870. https://doi.org/10.1016/j.landig.2025.03.002

Cabrejas-Olalla, A., Jørgensen, F. G., Cheng, J. Y., Kjærgaard, P. C., Schierup, M. H., Mailund, T. & Athanasiadis, G. (2025). Genetic predictions of eye and hair colour in the Danish population. Forensic Science International: Genetics, 78, Article 103267. https://doi.org/10.1016/j.fsigen.2025.103267

Strom, N. I., Gerring, Z. F., Galimberti, M., Yu, D., Halvorsen, M. W., Abdellaoui, A., Rodriguez-Fontenla, C., Sealock, J. M., Bigdeli, T., Coleman, J. R., Mahjani, B., Thorp, J. G., Bey, K., Burton, C. L., Luykx, J. J., Zai, G., Alemany, S., Andre, C., Askland, K. D. ... 23andMe Inc (2025). Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder. Nature Genetics, 57(6), 1389-1401. Article 230. https://doi.org/10.1038/s41588-025-02189-z

Andersen, H. H., Andersen, M. K., Bossow, K. A., Vestergaard, A. L., Bor, P. & Larsen, A. (2025). High-dose vitamin D supplementation in pregnancy ameliorates obesity-induced increase in maternal IL-1β level without affecting obesity-induced increase in IL-6 and MCP. The Journal of Steroid Biochemistry and Molecular Biology, 250, Article 106742. https://doi.org/10.1016/j.jsbmb.2025.106742

Garland, W. & Jensen, T. H. (2025). Integrator: A guardian against RNA-induced chaos. Cell Chemical Biology, 32(6), 780-782. https://doi.org/10.1016/j.chembiol.2025.05.009

Otzen, D. E., Peña-Díaz, S., Widmann, J., Daugberg, A. O. H., Zhang, Z., Jiang, Y., Mittal, C., Dueholm, M. K. D., Louros, N., Wang, H. & Javed, I. (2025). Interactions between pathological and functional amyloid: A match made in Heaven or Hell? Molecular Aspects of Medicine, 103, 101351. Article 101351. https://doi.org/10.1016/j.mam.2025.101351

Garcia-Morena, D., Fernandez-Cantos, M. V., Escalera, S. L., Lok, J., Iannone, V., Cancellieri, P., Maathuis, W., Panagiotou, G., Aranzamendi, C., Aidy, S. E., Kolehmainen, M., El-Nezami, H., Wellejus, A. & Kuipers, O. P. (2025). In Vitro Influence of Specific Bacteroidales Strains on Gut and Liver Health Related to Metabolic Dysfunction-Associated Fatty Liver Disease. Probiotics and antimicrobial proteins, 17(3), 1498-1512. Article 101314. https://doi.org/10.1007/s12602-024-10219-1

Staehr, C., Login, H., Melnikova, E., Bakun, M., Ziemlinska, E., Kisiswa, L., Berenji Ardestani, S., Nolte, S. S., Beck, H. C., Hansen, L. M. B., Postnov, D., Verkhratsky, A., Malik, A. R., Nykjær, A. & Matchkov, V. (2025). SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling. Acta Physiologica (Print), 241(6), Article e70052. https://doi.org/10.1111/apha.70052

Henriksen, F. O. G., Van, L. B., Brodersen, D. E. & Skjerning, R. B. (2025). Structural basis for higher-order DNA binding by a bacterial transcriptional regulator. PLoS Genetics, 21(6 June), Article e1011749. https://doi.org/10.1371/journal.pgen.1011749

McLain, A., Kowalczyk, A., Baran-Rachwalska, P., Sutera, F. M., Robertson, L. J., Nielsen, N. S., Enghild, J. J., Cobice, D., Bonelli, F., Barbaro, V., Ferrari, S., Patterson, B., Moore, L., Marshall, J., Nesbit, M. A. & Moore, T. (2025). TGFBI R124H mutant allele silencing in granular corneal dystrophy type 2 using topical siRNA delivery. Journal of Controlled Release, 382, Article 113681. https://doi.org/10.1016/j.jconrel.2025.113681

Kjær, A., Kristjánsdóttir, N., Juul, R. I., Nordentoft, I., Birkenkamp-Demtröder, K., Ahrenfeldt, J., Strandgaard, T., Radif, D., Hodgson, D., Abbosh, C., Aerts, H. J. W. L., Agerbæk, M., Jensen, J. B., Birkbak, N. J. & Dyrskjøt, L. (2025). Low T cell diversity associates with poor outcome in bladder cancer: A comprehensive longitudinal analysis of the T cell receptor repertoire. Cell Reports Medicine, 6(5), Article 102101. https://doi.org/10.1016/j.xcrm.2025.102101

Nielsen, T. T., Bali, P., Grove, J., Mohr-Jensen, C., Werge, T., Dalsgaard, S., Børglum, A. D., Sonuga-Barke, E., Minnis, H., Corfield, E. C., Tbartz van Elst, L., Mattheisen, M., de Wit, M. M., Uddin, M. J., Anney, R. J. L., Scherer, S. W., Bourgeron, T., Polderman, T. J. C., Autism Spectrum Working Group of the Psychiatric Genomics Consortium & Demontis, D. (2025). Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses. JAMA Psychiatry, Article e0243639. Advance online publication. https://doi.org/10.1001/jamapsychiatry.2025.0828

Kofod Petersen, A., Forgie, A., Villesen, P. & Staun Larsen, L. (2025). 3D dental similarity quantification in forensic odontology identification. Forensic Science International, 370, Article 112462. https://doi.org/10.1016/j.forsciint.2025.112462

Andreasen, M. D., Souza, P. C. T., Schiøtt, B. & Zuzic, L. (2025). Creating Coarse-Grained Systems with COBY: Toward Higher Accuracy of Complex Biological Systems. Journal of Chemical Information and Modeling, 65(10), 4760-4766. https://doi.org/10.1021/acs.jcim.5c00069

Gadeberg, T. A. F., Jørgensen, M. H., Olesen, H. G., Lorentzen, J., Harwood, S. L., Almeida, A. V., Fruergaard, M. U., Jensen, R. K., Kanis, P., Pedersen, H., Tranchant, E., Petersen, S. V., Thøgersen, I. B., Kragelund, B. B., Lyons, J. A., Enghild, J. J. & Andersen, G. R. (2025). Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring. Nature Structural and Molecular Biology, 32(5), 884-895. Article 872536. https://doi.org/10.1038/s41594-024-01467-4

Pareek, C. S., Sachajko, M., Kalra, G., Sultana, S., Szostak, A., Chalaskiewicz, K., Kepka-Borkowska, K., Poławska, E., Ogłuszka, M., Pierzchała, D., Starzyński, R., Taniguchi, H., Juszczuk-Kubiak, E., Lepczyński, A., Ślaska, B., Kozera, W., Czarnik, U., Wysocki, P., Kadarmideen, H. N. ... Pierzchała, M. (2025). Identification of trait-associated microRNA modules in liver transcriptome of pig fed with PUFAs-enriched supplementary diet. Journal of Applied Genetics, 66(2), 389-407. https://doi.org/10.1007/s13353-024-00912-w

Bruhn, D., Griffin, K. L. & Møller, I. M. (2025). Importance of Timing of Dark Acclimation for Estimating Light Inhibition of Leaf Respiratory CO₂ Efflux. Plant, Cell & Environment, 48(5), 3151-3158. https://doi.org/10.1111/pce.15335

Midtgaard, S. R., Hansen, M. S., Drachmann, N., Geng, X., Blans, K. I. M., Møbjerg, M. M. F., Frølund, A. F., Rasmussen, J. T. & Ostenfeld, M. S. (2025). Industrial Scale Production and Characterization of a Whey Fraction Enriched in Extracellular Vesicle Material. Journal of Extracellular Biology, 4(5), Article e70044. https://doi.org/10.1002/jex2.70044