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Latest peer-reviewed publications at MBG

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Displaying results 151 to 136 out of 136

Peer-reviewed publications at MBG - all years

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Zhang, S., Ma, J., Riera Belles, M., Besenbacher, S., Niskanen, J. E., Salokorpi, N., Hundi, S., Hytönen, M. K., Zhou, T., Li, G.-M., Ostrander, E. A., Schierup, M. H., Lohi, H. & Wang, G.-D. (2025). Determinants of de novo mutations in extended pedigrees of 43 dog breeds. Genome Biology, 26(1), Article 305. https://doi.org/10.1186/s13059-025-03804-2

Zhang, T., Bär, J., Risberg, L., Gómez Mejia, A., Hammar, H., Löffler, S., Otzen, D. E., Andreasen, M., Meyer, R. L., Melican, K., Zinkernagel, A. S. & Richter-Dahlfors, A. (2025). Dynamic visualization of extracellular matrix components in S. aureus colony biofilms reveals functional amyloids leading to the formation of cap-like structures. Biofilm, 10, Article 100318. https://doi.org/10.1016/j.bioflm.2025.100318

Garde, C., Pavlidis, M. A., Garces, P., Lange, E. J., Ramarathinam, S. H., Sokač, M., Pandey, K., Faridi, P., Ahrenfeldt, J., Chung, S., Friis, S., Kleine-Kohlbrecher, D., Birkbak, N. J., Kringelum, J. V., Rønø, B., Purcell, A. W. & Trolle, T. (2025). Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines. npj Vaccines, 10(1), Article 54. https://doi.org/10.1038/s41541-025-01107-y

Rasmussen, C. L. M., Frederiksen, S. F., Heegaard, C. W., Thomsen, M. S., Hede, E., Laczek, B., Körbelin, J., Wüstner, D., Thomsen, L. B., Schwaninger, M., Jensen, O. N., Moos, T. & Burkhart, A. (2025). Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2. Fluids and Barriers of the CNS, 22(1), Article 13. https://doi.org/10.1186/s12987-025-00621-4

Qin, Q., Wei, P., Usman, S., Ahamefule, C. S., Jin, C., Wang, B., Yan, K., van Aalten, D. M. F. & Fang, W. (2025). Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence. BMC Biology, 23(1), Article 80. https://doi.org/10.1186/s12915-025-02184-0

Gómez-Repollés, A., Villa-Rodríguez, E., Blahovska, Z., Ferguson, S. & Radutoiu, S. (2025). High-quality genome assemblies of 152 root commensal bacteria from the model legume Lotus japonicus. Scientific Data, 12(1), Article 1793. https://doi.org/10.1038/s41597-025-06078-2

Hjelholt, A. J., Gholipourshahraki, T., Bai, Z., Shrestha, M., Kjolby, M., Sørensen, P. & Rohde, P. D. (2025). Leveraging genetic correlations to prioritize drug groups for repurposing in type 2 diabetes. The Pharmacogenomics Journal, 25(6), Article 33. https://doi.org/10.1038/s41397-025-00392-z

Porsborg, P. S., Charmouh, A. P., Singh, V. K., Winge, S. B., Hvilsom, C., Oroperv, C., Hansen, L. T., Berner, J. A., Pelizzola, M., Laurentino, S., Neuhaus, N., Hobolth, A., Bataillon, T., Besenbacher, S., Almstrup, K. & Schierup, M. H. (2025). Long-read sequencing of primate testis and human sperm allows identification of recombination events in individuals. Nature Communications, 16(1), Article 10337. https://doi.org/10.1038/s41467-025-65248-3

Morin, M., Yin, W., MacLean, H., Devlin, B., Reichenberg, A., Swan, S. H., Buxbaum, J. D., Schendel, D., Persson, M., Laursen, T. M., Kolevzon, A., Grove, J., Klei, L., Roeder, K. & Sandin, S. (2025). Maternal body mass index in early pregnancy and autism in offspring: a population-based cohort study in Sweden and Denmark. BMC Medicine, 23(1), Article 620. https://doi.org/10.1186/s12916-025-04487-z

Hansen, S. B., Bartual, S. G., Yuan, H., Raimi, O. G., Gorelik, A., Ferenbach, A. T., Lytje, K., Pedersen, J. S., Drace, T., Boesen, T. & van Aalten, D. M. F. (2025). Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms. Nature Communications, 16(1), Article 8828. https://doi.org/10.1038/s41467-025-63893-2

Bryzek, D., Gasiorek, A., Kowalczyk, D., Santocki, M., Ciaston, I., Dobosz, E., Kolaczkowska, E., Kjøge, K., Kantyka, T., Lech, M., Potempa, B., Enghild, J. J., Potempa, J. & Koziel, J. (2025). Non-classical neutrophil extracellular traps induced by PAR2-signaling proteases. Cell Death & Disease, 16(1), Article 109. https://doi.org/10.1038/s41419-025-07428-z

Andersen-Civil, A. I. S., Mantel, M., Soh, J., Mostowy, S., Brugman, S. & Vanwalleghem, G. C. (2025). Novel and unscrutinized immune entities of the zebrafish gut. FEBS Letters, 599(23), 3444-3455. https://doi.org/10.1002/1873-3468.70161

Vuille-dit-Bille, E., Utz, L., Müllner, F. E., Arteaga-Moreta, V. J., Hou, Y., Spirig, S. E., Ledroit-Paic, D., Heub, S., Goldowsky, J., Weder, G. & Renner, M. (2025). PEGDA-based HistoBrick for increasing throughput of cryosectioning and immunohistochemistry in organoid and small tissue studies. Scientific Reports, 15(1), Article 412. https://doi.org/10.1038/s41598-024-83164-2

Waligórska, I., Żak, K. M., Mikrut, N., Budziaszek, J., Medviediev, V., Bielecka, E., Kantyka, T., Kozieł, J., Thøgersen, I. B., Enghild, J. J., Grudnik, P., Potempa, J. & Książek, M. (2025). Periodontopathogens degrade angiotensin I from the human renin-angiotensin system through surface-attached proteases. Scientific Reports, 15(1), Article 43309. https://doi.org/10.1038/s41598-025-27891-0

Gobet, A., Moissonnier, L., Zarkadas, E., Magnard, S., Bettler, E., Martin, J., Terreux, R., Schoehn, G., Orelle, C., Jault, J. M., Falson, P. & Chaptal, V. (2025). Rhodamine6G and Hœchst33342 narrow BmrA conformational spectrum for a more efficient use of ATP. Nature Communications, 16(1), Article 1745. https://doi.org/10.1038/s41467-025-56849-z

Thorsen, T. S., Kulkarni, Y., Sykes, D. A., Bøggild, A., Drace, T., Hompluem, P., Iliopoulos-Tsoutsouvas, C., Nikas, S. P., Daver, H., Makriyannis, A., Nissen, P., Gajhede, M., Veprintsev, D. B., Boesen, T., Kastrup, J. S. & Gloriam, D. E. (2025). Structural basis of THC analog activity at the Cannabinoid 1 receptor. Nature Communications, 16(1), Article 486. https://doi.org/10.1038/s41467-024-55808-4

Zaheer, S., Baindoor, S., Connolly, N. M. C., Siebenbrodt, K., Bauer, S., Rosenow, F., Andersen, J. S., Venø, M. T., Kjems, J., Henshall, D. C. & Prehn, J. H. M. (2025). Temporal Dynamics of tsRNA Regulation Mark an Abrupt Transition After Epileptogenesis. Journal of Neurochemistry, 169(12), Article e70317. https://doi.org/10.1111/jnc.70317

Wang, X., Nursyifa, C., Aninta, S. G., Garcia-Erill, G., Bertola, L. D., Khan, A., Kuja, J., Hanghøj, K., Meisner, J., Bøggild, T., Bradshaw, C. J. A., Al-Chaer, A., Persada, A. P., Priyono, D. S., Tribudi, Y. A., Sudrajad, P., Gaina, C. D., Jiang, Y., Lenstra, J. A. ... Heller, R. (2025). The genetic diversity of Indonesian cattle has been shaped by multiple introductions and adaptive introgression. Nature Communications, 16(1), Article 8192. https://doi.org/10.1038/s41467-025-62692-z

Montiel, J., García-Soto, I., Monroy-Morales, E., Lace, B., Robledo-Gamboa, M., Vestergaard, M., Sandal, N., Ott, T. & Stougaard, J. (2025). The Lotus japonicus alpha-expansin EXPA1 is recruited during intracellular and intercellular rhizobial colonization. Plant Journal, 124(5), Article e70639. https://doi.org/10.1111/tpj.70639

Novosylna, O., Shalak, V., Dąbrowska, K., Patmanidis, I., Lozhko, D., Bondarchuk, T., Schiøtt, B., Pedersen, J. S., Knudsen, C. R., Nissen, P., Dadlez, M. & Negrutskii, B. (2025). Dynamics and structural features of the eEF1A1 and eEF1A2 paralogs. Nucleic Acids Research, 53(21), Article gkaf1177. https://doi.org/10.1093/nar/gkaf1177

Jiang, Y. & Kjems, J. (2025). RNA denaturation underlies circular RNA separation. Nucleic Acids Research, 53(21), Article gkaf1160. https://doi.org/10.1093/nar/gkaf1160

Yu, X., Liu, C. D., Shen, S., Kim, E. S., Liu, Z., Zhang, H., Sun, N., Liu, Y., Martensen, P. M., Huang, Y. & Guo, H. (2025). Interferon alpha-inducible protein 27 (IFI27) inhibits hepatitis B virus (HBV) transcription through downregulating cellular transcription factor C/EBPα. Journal of Virology, 99(11), e0150925. https://doi.org/10.1128/jvi.01509-25

Hussein, A., Zhang, X., Pedersen, B. P. & Stokes, D. L. (2025). Conduction pathway for potassium through the Escherichia coli pump KdpFABC. eLife, 14. https://doi.org/10.7554/eLife.107397

Jansen, S. A. H., Dreyer, L. S. A., van Basten, J., Yao, Y., Otzen, D. E., de Greef, T. F. A., Knowles, T. P. J., Meijer, E. W. & Erkamp, N. A. (2025). PhaseXplorer Creates High-Dimensional Phase Diagrams with Closed-Loop Active Learning. ACS Nano, 19(45), 38981-38989. https://doi.org/10.1021/acsnano.5c07268

Skovbjerg, C. K., Sarup, P., Wahlström, E. M., Jensen, J. D., Olesen, L., Orabi, J., Jensen, J., Ramstein, G. P. & Jahoor, A. (2025). Genomic prediction in a small barley population can benefit from training on related populations. G3 (Bethesda, Md.), 15(11). https://doi.org/10.1093/g3journal/jkaf218, https://doi.org/10.1093/g3journal/jkaf218

Gabs, E., Aalto-Setälä, E., Välisaari, A., Malinen, A. M., Jensen, T. H., McLaughlin, S. H., Passmore, L. A. & Turtola, M. (2025). A kinetic ruler controls mRNA poly(A) tail length. Genes & Development, 39(21-22), 1377-1394. https://doi.org/10.1101/gad.352912.125

Muñoz-Juan, A., Laromaine, A., Yuste, V. J. & Dalfó, E. (2025). Assessing Gastrointestinal Motility in Caenorhabditis elegans RAC1/CED-10 Mutants as a Tool to Study Early Parkinson's Disease. Journal of Visualized Experiments, 2025(225), Article e69278. https://doi.org/10.3791/69278

Kobek-Kjeldager, C., Jensen, L. D., Foldager, L., Kaiser, M., Thodberg, K. & Herskin, M. S. (2025). Corrigendum to:“Deck height did not affect behavioural measures of ‘natural movements’ and ‘adequate ventilation’ during 8 h and 23 h transport of weaner pigs” (Applied Animal Behaviour Science, (2025), 290, C, (106714), (S0168159125002126), 10.1016/j.applanim.2025.106714). Applied Animal Behaviour Science, 292, Article 106793. https://doi.org/10.1016/j.applanim.2025.106793

Mishra, A., Golbek, T. W., Thomassen, A. B., Zuzic, L., Schmüser, L., Saeed, K. H., Madzharova, F., Nielsen, J., Schiøtt, B., Otzen, D. E. & Weidner, T. (2025). Pathological Folding of α-Synuclein on Polystyrene Nanoplastic Revealed by Sum Frequency Scattering and 2D Infrared Spectroscopy. The Journal of Physical Chemistry Letters, 16(45), 11893-11900. https://doi.org/10.1021/acs.jpclett.5c02526

Zhang, B.-C., Pedersen, A., Reinert, L. S., Li, Y., Narita, R., Idorn, M., Hu, L., Skouboe, M. K., Li, S., Maimaitili, M., Ding, X., Cong, Y., Zhao, J., Frémond, M.-L., Mikkelsen, K., Gao, Z., Huang, J.-R., Thomsen, E. A., Mikkelsen, J. H. ... Paludan, S. R. (2025). STING signals to NF-κB from late endolysosomal compartments using IRF3 as an adaptor. Nature Immunology, 26(11), 1916-1930. https://doi.org/10.1038/s41590-025-02283-8

Silale, A., Madej, M., Mikruta, K., Frey, A. M., Hart, A. J., Baslé, A., Scavenius, C., Enghild, J. J., Trost, M., Hirt, R. P. & van den Berg, B. (2025). Structure of a distinct β-barrel assembly machinery complex in the Bacteroidota. Nature Microbiology, 10(11), 2845-2859. https://doi.org/10.1038/s41564-025-02132-2

Pravata, V. M., Jiang, H., Ferenbach, A. T., Lamond, A. & van Aalten, D. M. F. (2025). Zscan4 as a Candidate Conveyor of Early Developmental Defects in O-GlcNAc Transferase Intellectual Disability. Molecular & Cellular Proteomics : MCP, 24(11), Article 101077. https://doi.org/10.1016/j.mcpro.2025.101077

Zhang, X., Grove, J., Gu, Y., Buus, C. K., Nielsen, L. K., Neufeld, S. A. S., Koko, M., Malawsky, D. S., Wade, E. M., Verhoef, E., Gui, A., Hegemann, L., Geschwind, D. H., Wray, N. R., Havdahl, A., Ronald, A., St Pourcain, B., Robinson, E. B., Bourgeron, T. ... APEX consortium (2025). Polygenic and developmental profiles of autism differ by age at diagnosis. Nature, 646(8087), 1146-1155. https://doi.org/10.1038/s41586-025-09542-6

Ramos Docampo, M. A., Abild Meyer, C., Ryberg, C., Otzen, D. E., Hirsch, C. & Städler, B. (2025). Actin Polymerizing Motors to Assist Cytoskeleton-like Networks Formation in Artificial Cells. ACS Nano, 19(42), 37324-37338. https://doi.org/10.1021/acsnano.5c12624

Castenschiold, C. D. F., Mignani, C., Christiansen, S., Alsved, M., Ickes, L., Tesson, S. V. M., Löndahl, J., Bilde, M., Bataillon, T., Finster, K. & Šantl-Temkiv, T. (2025). Atmospheric Biogenic Ice-Nucleating Particles Link to Microbial Communities in the Arctic Marine Environment in Western Greenland. Environmental Science and Technology, 59(42), 22518-22532. https://doi.org/10.1021/acs.est.5c03650

Teodori, L., Shahrokhtash, A., Sørensen, E. A., Zhang, X., Malle, M. G., Sutherland, D. S. & Kjems, J. (2025). Nanoscale Precise Stamping of Biomolecule Patterns Using DNA Origami. ACS Nano, 19(42), 36931-36942. https://doi.org/10.1021/acsnano.5c07651

Korsgaard, U., Kristensen, M. P., García-Rodríguez, J. L., Kjær-Frifeldt, S., Lindebjerg, J., Hansen, T. F., Kjems, J., Hager, H. & Kristensen, L. S. (2025). The prognostic potential of RNA in stage II colon cancer: Insights from a screened multicenter population-based cohort study. International Journal of Cancer, 157(8), 1746-1755. https://doi.org/10.1002/ijc.35507

Yadav, S. K., Kidmose, R. T. & Lorentzen, E. (2025). Intraflagellar transport: How kinesin motors hook onto their trains. Current Biology, 35(19), R928-R931. https://doi.org/10.1016/j.cub.2025.08.049

De Dios Andres, P., Purup, A. B., Beaune, G., Timonen, J. V. I., Lyons, J. A. & Städler, B. (2025). Flippase-Mediated Hybrid Vesicle Division. Advanced Materials, 37(39), Article 2504519. https://doi.org/10.1002/adma.202504519

Elsborg, J. D., Munk, S. H. N., Adelantado-Rubio, A., Pék, R., Fábian, Z., Imburchia, V., Zentout, S., Hendriks, I. A., Buch-Larsen, S. C., Smith, R., Bartek, J., Duxin, J. P., Huet, S., Maya-Mendoza, A. & Nielsen, M. L. (2025). PARP1 auto-modification promotes faithful Okazaki fragment processing and limits replication fork speed. Molecular Cell, 85(19), 3562-3575.e10. https://doi.org/10.1016/j.molcel.2025.09.006

Teixeira, L. M. C., Paiva, P., Ferreira, P., Rotilio, L., Morth, J. P., Otzen, D. E., Fernandes, P. A. & Ramos, M. J. (2025). Bridging experiment and theory: a computational exploration of UMG-SP3 dynamics. Pure and Applied Chemistry, 97(10), 1405-1418. https://doi.org/10.1515/pac-2025-0489

Asenjo-Martinez, A., Dragicevic, K., Hou, W. H., Ozsvar, A., Winther Hansen, N., Pfisterer, U., Rydbirk, R., Demharter, S., Møller, B. E., Gasthaus, J., Korshunova, I., Perrier, J. F., Capogna, M., Vasistha, N. A. & Khodosevich, K. (2025). Dysfunction of cortical GABAergic projection neurons as a major hallmark in a model of neuropsychiatric syndrome. Neuron, 113(19), 3204-3223. https://doi.org/10.1016/j.neuron.2025.08.028

Segur-Bailach, E., Mateu-Bosch, A., Bofill-De Ros, X., Parés, M., da Silva Buttkus, P., Rathkolb, B., Gailus-Durner, V., Hrabě de Angelis, M., Moeini, P., Gonzalez-Aseguinolaza, G., Tort, F., Ribes, A., van Karnebeek, C. D. M., García-Villoria, J. & Fillat, C. (2025). Therapeutic AASS inhibition by AAV-miRNA rescues glutaric aciduria type I severe phenotype in mice. Molecular Therapy, 33(10), 4820-4833. https://doi.org/10.1016/j.ymthe.2025.07.022

Kapelyukh, Y., Gabel-Jensen, C., MacLeod, A. K., Daniel Coquelin, K. S., Stojanovski, L., Frame, L., Tavendale, A., Henderson, C. J., Read, K. D., Wolf, C. R. & Säll, C. (2025). Application of a mouse model humanized for cytochrome P450–mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs. Drug Metabolism and Disposition, 53(10), Article 100153. https://doi.org/10.1016/j.dmd.2025.100153

Søkilde, R., Kaadt, E., Kristensen, L. S., Venø, M. T., Kjems, J., Nyengaard, J. R., Nielsen, B. S. & Elfving, B. (2025). Application of microRNA In Situ Hybridization on Long-term Stored Human Formalin-fixed Paraffin-embedded Brain Samples from Psychiatric Patients. Molecular Neurobiology, 62(10), 12736-12746. https://doi.org/10.1007/s12035-025-05077-z

Kofod Petersen, A., Mânica, S., Forgie, A., Boyle, R., Pandey, H., Villesen, P. & Staun Larsen, L. (2025). Charred or fragmented, yet comparable: Quantifying dental surface dissimilarity across teeth, jaws, and heat exposure. Forensic Science International, 375, Article 112577. https://doi.org/10.1016/j.forsciint.2025.112577

Dardani, C., Robinson, J. W., Jones, H. J., Rai, D., Stergiakouli, E., Grove, J., Gardner, R., McIntosh, A. M., Havdahl, A., Hemani, G., Davey Smith, G., Richardson, T. G., Gaunt, T. R. & Khandaker, G. M. (2025). Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions. Molecular Psychiatry, 30(10), 4487-4496. Article e1004092. https://doi.org/10.1038/s41380-025-03032-x

Pinheiro, F., Nowak, J. S., Zueva, E., Pheasant, E. C., Grene, I. K., Lampinen, V. & Kjaergaard, M. (2025). Screening de novo designed protein binders in unpurified lysate using flow induced dispersion analysis. Protein Science, 34(10), Article e70286. https://doi.org/10.1002/pro.70286

Bro̷chner, B. V., Zhang, X., Nielsen, J., Kjems, J., Otzen, D. E. & Malle, M. G. (2025). Single-vesicle Tracking of α-Synuclein Oligomers Reveals Pore Formation by a Three-Stage Model. ACS Nano, 19(36), 32108-32122. https://doi.org/10.1021/acsnano.5c04005

Buhl, J. M., Mahapatra, S., Kjærgaard, M. & Mulder, F. A. A. (2025). Quantification of Small Molecule Partitioning in a Biomolecular Condensate with 2D Nuclear Magnetic Resonance Spectroscopy. ChemBioChem, 26(17), Article e202500401. https://doi.org/10.1002/cbic.202500401

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Lisbeth Heilesen