During her PhD studies, Bente Kring Hansen’s research was focused on developing fluorescence-based biosensors to measure glucagon-like peptide-1 (GLP-1) secretion from yeast. The aim of the project was to use these biosensors to set up a high-throughput screening platform for isolating high-producing yeast strains at Novo Nordisk. Bente Kring Hansen investigated the potential of developing sensors based on identifying novel nucleic acid aptamers as well as the use of commercially available antibodies in new epitope tagging based immunoassays.
The PhD study was completed at Interdisciplinary Nanoscience Center (iNANO), Faculty of Natural Sciences, Aarhus University and Novo Nordisk A/S, Måløv.

This summary was prepared by the PhD student.

Time: Thursday, 27 October 2022 at 13:00
Place: Building 1593, room 012, iNANO AUD, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C
Title of PhD thesis: Development of fluorescent sensors for high-throughput screening of yeast production strains in droplets

Contact information: Bente Kring Hansen, e-mail: bentekh@inano.au.dk, tel.: +45 20371861

Members of the assessment committee:

Professor Beatrix Suess, Department of Biology, Technical University Darmstadt, Germany

Senior Research Fellow Berit Olsen Krogh, H. Lundbeck A/S, Denmark

Associate Professor Ken Howard (chair), iNANO, Aarhus University, Denmark

Main supervisor:
Associate Professor Ebbe Sloth Andersen, iNANO, Aarhus University, Denmark

Co-supervisor:
Senior Scientist Vera Schramke, Novo Nordisk A/S, Måløv, Denmark

Language: The PhD dissertation will be defended in English

The defence is public.
The PhD thesis is available for reading at the Graduate School of Natural Sciences/GSNS,

Jens Baggesens Vej 53, building 5221, 8200 Aarhus N.