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Marie Bech Andersen: Investigating the import of membrane proteins to cilia from a structural and biochemical perspective

PhD defence, Friday, 11 June 2021. Marie Bech Andersen

Marie Bech Andersen

During her PhD studies, Marie Bech Andersen investigated how membrane proteins are transported into the cilium, a hair-like structure found on the surface of essentially all cells in our body. From here, the membrane proteins carry out important signaling functions e.g. during embryonic development. Marie Bech Andersen studied how Tubby-like protein 3 acts as an adaptor between certain membrane proteins and the Intraflagellar transport system, which facilitates transport within the cilium.

The new research findings contribute to the understanding of how cilia carry out their signaling function by regulating the import and export of signaling components.

The PhD study was completed at Molecular Biology and Genetics, Faculty of Natural Sciences, Aarhus University.

This summary was prepared by the PhD student.

 Friday, 11 June 2021 at 13:00
Place: The PhD defence will be held online. To receive a link to the event, please send an e-mail to Esben Lorenzen (el@mbg.au.dk)
Title of PhD thesis: Structural and biochemical characterization of Tulp3 and its role in ciliary import of membrane proteins

Contact information: Marie Bech Andersen e-mail: mba@mbg.au.dk, tel.: +45 28 73 72 69

Members of the assessment committee:

Professor Søren T. Christensen, Institute of biology, Copenhagen University, Denmark

Senior Researcher Atlanta Cook, Institute for Quantitative Biology, Biochemistry, and Biotechnology, University of Edinburgh, Scotland

Associate Professor Ernst-Martin Füchtbauer (chairman), Department of Molecular Biology and Genetics, Aarhus University, Denmark

Main supervisor:
Associate Professor Esben Lorentzen, Department of Molecular Biology and Genetics, Aarhus University, Denmark

Language: The PhD dissertation will be defended in English

The defence is public.
Due to the coronavirus situation, the PhD thesis will not be available for reading at the offices of the PhD administration. Instead, interested parties may send an e-mail to gradschool.nat@au.dk to receive a digital copy of the PhD thesis. Please note, it may in certain cases be necessary to make an individual arrangement to read the PhD thesis.