Meyer, F., Fritz, A., Deng, Z. L., Koslicki, D., Lesker, T. R., Gurevich, A., Robertson, G., Alser, M., Antipov, D., Beghini, F., Bertrand, D., Brito, J. J., Brown, C. T., Buchmann, J., Buluç, A., Chen, B., Chikhi, R., Clausen, P. T. L. C., Cristian, A. ... McHardy, A. C. (2022).
Critical Assessment of Metagenome Interpretation: the second round of challenges.
Nature Methods,
19(4), 429-440.
https://doi.org/10.1038/s41592-022-01431-4
Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J. A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B. H., Ermolaeva, M., Ewald, C. Y., Ferrucci, L., Florian, M. C. ... Scheibye-Knudsen, M. (2022).
Meeting Report: Aging Research and Drug Discovery.
Aging,
14(2), 532-543.
https://doi.org/10.18632/aging.203859
Meisl, G., Xu, C. K., Taylor, J. D., Michaels, T. C. T., Levin, A.
, Otzen, D., Klenerman, D., Matthews, S., Linse, S.
, Andreasen, M. & Knowles, T. P. J. (2022).
Uncovering the universality of self-replication in protein aggregation and its link to disease.
Science Advances,
8(32), Article eabn6831.
https://doi.org/10.1126/sciadv.abn6831
Matzke, M.
, Toft, S., Bechsgaard, J., Pold Vilstrup, A., Uhl, G., Künzel, S.
, Tuni, C. & Bilde, T. (2022).
Sperm competition intensity affects sperm precedence patterns in a polyandrous gift-giving spider.
Molecular Ecology,
31(8), 2435-2452.
https://doi.org/10.1111/mec.16405
Mattheisen, M., Grove, J., Als, T. D., Martin, J., Voloudakis, G.
, Meier, S., Demontis, D., Bendl, J., Walters, R., Carey, C. E., Rosengren, A.
, Strom, N. I., Hauberg, M. E., Zeng, B., Hoffman, G., Zhang, W., Bybjerg-Grauholm, J., Bækvad-Hansen, M.
, Agerbo, E. ... Børglum, A. D. (2022).
Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups.
Nature Genetics,
54(10), 1470-1478.
https://doi.org/10.1038/s41588-022-01171-3
Martín-Rivada, Á., Guerra-Cantera, S., Campillo-Calatayud, A., Andrés-Esteban, E. M., Sánchez Holgado, M., Martos-Moreno, G., Pozo, J., Güemes, M., Soriano-Guillén, L., Pellicer, A.
, Oxvig, C., Frystyk, J., Chowen, J. A., Barrios, V. & Argente, J. (2022).
Pappalysins and Stanniocalcins and Their Relationship With the Peripheral IGF Axis in Newborns and During Development.
The Journal of clinical endocrinology and metabolism,
107(10), 2912-2924.
https://doi.org/10.1210/clinem/dgac453
Marquez-Legorreta, E., Constantin, L., Piber, M., Favre-Bulle, I. A., Taylor, M. A., Blevins, A. S., Giacomotto, J., Bassett, D. S.
, Vanwalleghem, G. C. & Scott, E. K. (2022).
Brain-wide visual habituation networks in wild type and fmr1 zebrafish.
Nature Communications,
13(1), Article 895.
https://doi.org/10.1038/s41467-022-28299-4
Märcher, A., Kumar, V., Andersen, V. L., El-Chami, K., Nguyen, T. J. D., Skaanning, M. K., Rudnik-Jansen, I., Nielsen, J. S., Howard, K. A., Kjems, J. & Gothelf, K. V. (2022).
Functionalized Acyclic (l)-Threoninol Nucleic Acid Four-Way Junction with High Stability In Vitro and In Vivo.
Angewandte Chemie - International Edition,
61(24), Article 202115275.
https://doi.org/10.1002/anie.202115275
Madzharova, F., Bregnhøj, M., Chatterley, A. S., Løvschall, K. B., Drace, T., Andersen Dreyer, L. S., Boesen, T. & Weidner, T. (2022).
Electrostatics Trigger Interfacial Self-Assembly of Bacterial Ice Nucleators.
Biomacromolecules,
23(2), 505-512.
https://doi.org/doi.org/10.1021/acs.biomac.1c01217
Maccio, U., Mihic, A., Lenggenhager, D., Kolm, I., Mittmann, C., Heikenwälder, M.
, Lorentzen, A. & Mihic-Probst, D. (2022).
Hypoxia and Ezrin Expression in Primary Melanoma Have High Prognostic Relevance.
International Journal of Molecular Sciences ,
23(18), Article 10745.
https://doi.org/10.3390/ijms231810745
Lucotte, E. A., Albiñana, C., Laurent, R., Bhérer, C.
, Bataillon, T., Toupance, B. & Genome of the Netherland Consortium (2022).
Detection of sexually antagonistic transmission distortions in trio datasets.
Evolution Letters,
6(2), 203-216.
https://doi.org/10.1002/evl3.271
López de Las Hazas, M. C., Del Pozo-Acebo, L.
, Hansen, M. S., Gil-Zamorano, J., Mantilla-Escalante, D. C., Gómez-Coronado, D., Marín, F., Garcia-Ruiz, A.
, Rasmussen, J. T. & Dávalos, A. (2022).
Dietary bovine milk miRNAs transported in extracellular vesicles are partially stable during GI digestion, are bioavailable and reach target tissues but need a minimum dose to impact on gene expression.
European Journal of Nutrition,
61(2), 1043-1056.
https://doi.org/10.1007/s00394-021-02720-y
Leslie, J. S., Hjeij, R., Vivante, A., Bearce, E. A., Dyer, L.
, Wang, J., Rawlins, L., Kennedy, J., Ubeyratna, N., Fasham, J., Irons, Z. H., Craig, S. B., Koenig, J., George, S., Pode-Shakked, B., Bolkier, Y., Barel, O., Mane, S.
, Frederiksen, K. K. ... Baple, E. L. (2022).
Biallelic DAW1 variants cause a motile ciliopathy characterized by laterality defects and subtle ciliary beating abnormalities.
Genetics in Medicine,
24(11), 2249-2261.
https://doi.org/10.1016/j.gim.2022.07.019
Lassen, L. B., Thomsen, M. S., Basso, E.
, Füchtbauer, E. M., Füchtbauer, A., Outeiro, T. F.
, Jensen, P. H. & Moos, T. (2022).
Mutation of Tyrosine Sites in the Human Alpha-Synuclein Gene Induces Neurotoxicity in Transgenic Mice with Soluble Alpha-Synuclein Oligomer Formation.
Cells,
11(22), Article 3673.
https://doi.org/10.3390/cells11223673
Langousis, G., Cavadini, S.
, Boegholm, N., Lorentzen, E., Kempf, G. & Matthias, P. (2022).
Structure of the ciliogenesis-associated CPLANE complex.
Science Advances,
8(15), Article eabn0832.
https://doi.org/10.1126/sciadv.abn0832
Kodesh, A., Levine, S. Z., Khachadourian, V., Rahman, R., Schlessinger, A., O'Reilly, P. F.
, Grove, J., Schendel, D., Buxbaum, J. D., Croen, L., Reichenberg, A., Sandin, S. & Janecka, M. (2022).
Maternal health around pregnancy and autism risk: a diagnosis-wide, population-based study.
Psychological Medicine,
52(16), 4076-4084.
https://doi.org/10.1017/S0033291721001021
Kobek-Kjeldager, C., Jensen, L. D., Foldager, L., Kaiser, M., Thodberg, K. & Herskin, M. S. (2022).
Validation of behavioural sampling techniques for 20-25 kg pigs during 23-hour transport. In M. Kjosevski, S. Waiblinger & V. Ilieski (Eds.),
Proceedings of the 55th Congress of the ISAE: Animal Behaviour and Beyond (pp. 167-167).
https://www.applied-ethology.org/res/ISAE_2022_PROCEEDINGS_e-version.pdf
Kobberø, S. D., Gajhede, M., Mirza, O. A.
, Kløverpris, S., Kjær, T. R., Mikkelsen, J. H., Boesen, T. & Oxvig, C. (2022).
Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism.
Nature Communications,
13(1), Article 6084.
https://doi.org/10.1038/s41467-022-33698-8
Kjærgaard, M., Rasmussen, L. S., Vinther, J. N., Andersen, K. R., Andersen, E. S., Lorentzen, E., Thirup, S. S., Otzen, D. & Brodersen, D. E. (2022).
A Semester-Long Learning Path Teaching Computational Skills via Molecular Graphics in PyMOL.
The Biophysicist,
3(2), 106–114.
https://doi.org/10.35459/tbp.2022.000219
Khateb, H., Sørensen, R. S., Cramer, K., Eklund, A. S.
, Kjems, J., Meyer, R. L., Jungmann, R.
& Sutherland, D. S. (2022).
The Role of Nanoscale Distribution of Fibronectin in the Adhesion of Staphylococcus aureus Studied by Protein Patterning and DNA-PAINT.
ACS Nano,
16(7), 10392-10403.
https://doi.org/10.1021/acsnano.2c00630
Keller, J. G., Hymøller, K. M., Thorsager, M. E., Hansen, N. Y., Erlandsen, J. U., Tesauro, C., Simonsen, A. K. W., Andersen, A. B., Vandsø Petersen, K., Holm, L. L.
, Stougaard, M., Andresen, B. S., Kristensen, P., Frøhlich, R.
& Knudsen, B. R. (2022).
Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation.
Nucleic Acids Research,
50(11), 6332-6342.
https://doi.org/10.1093/nar/gkac482
Keller, J. G., Mizielinski, K.
, Petersen, K. V., Stougaard, M., Knudsen, B. R. & Tesauro, C. (2022).
Simple and Fast Rolling Circle Amplification-Based Detection of Topoisomerase 1 Activity in Crude Biological Samples.
Journal of visualized experiments : JoVE,
190, Article e64484.
https://doi.org/10.3791/64484
Jiang, M., Dai, S., Zheng, Y. C., Li, R. Q., Tan, Y. Y., Pan, G.
, Møller, I. M., Song, S. Y., Huang, J. Z. & Shu, Q. Y. (2022).
An alanine to valine mutation of glutamyl-tRNA reductase enhances 5-aminolevulinic acid synthesis in rice.
Theoretical and Applied Genetics,
135(8), 2817-2831.
https://doi.org/10.1007/s00122-022-04151-7
Jepsen, M. R., Østergaard, J. A., Conover, C. A.
, Wogensen, L., Birn, H., Krag, S. P., Fenton, R. A. & Oxvig, C. (2022).
Increased activity of the metalloproteinase PAPP-A promotes diabetes-induced glomerular hypertrophy.
Metabolism: Clinical and Experimental,
132, Article 155218.
https://doi.org/10.1016/j.metabol.2022.155218
Jensen, R. K., Pedersen, H., Lorentzen, J., Laursen, N. S., Vorup-Jensen, T. & Andersen, G. R. (2022).
Structural insights into the function-modulating effects of nanobody binding to the integrin receptor αMβ2.
Journal of Biological Chemistry,
298(8), Article 102168.
https://doi.org/10.1016/j.jbc.2022.102168
Jankowski, V., Saritas, T.
, Kjolby, M., Hermann, J., Speer, T., Himmelsbach, A., Mahr, K., Heuschkel, M. A., Schunk, S. J.
, Thirup, S., Winther, S., Bottcher, M., Nyegard, M.
, Nykjaer, A., Kramann, R., Kaesler, N., Jankowski, J., Floege, J., Marx, N. & Goettsch, C. (2022).
Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease.
Kidney International,
101(3), 574-584.
https://doi.org/10.1016/j.kint.2021.10.018
Jakobsen, A. K., Yuusufi, S., Madsen, L. B., Meldgaard, P., Knudsen, B. R. & Stougaard, M. (2022).
TDP1 and TOP1 as targets in anticancer treatment of NSCLC: Activity and protein level in normal and tumor tissue from 150 NSCLC patients correlated to clinical data.
Lung Cancer,
164, 23-32.
https://doi.org/10.1016/j.lungcan.2021.12.010
Jakobsen, A-K., Yuusufi, S., Madsen, L. B., Meldgaard, P., Knudsen, B. R. & Stougaard, M. (2022).
TDP1 and TOP1 as targets in anticancer treatment of NSCLC: Activity and protein level in normal and tumor tissue from 150 NSCLC patients correlated to clinical data.
Lung Cancer,
164, 23-32.
https://doi.org/10.1016/j.lungcan.2021.12.010
Henriksen, T. V., Drue, S. O., Frydendahl, A., Demuth, C., Rasmussen, M. H., Reinert, T., Pedersen, J. S. & Andersen, C. L. (2022).
Error Characterization and Statistical Modeling Improves Circulating Tumor DNA Detection by Droplet Digital PCR.
Clinical Chemistry,
68(5), 657-667.
https://doi.org/10.1093/clinchem/hvab274
He, J., Steffen, J. H., Thulstrup, P. W.
, Pedersen, J. N., Sauerland, M. B.
, Otzen, D. E., Hawkins, C. L., Gourdon, P., Davies, M. J. & Hägglund, P. (2022).
Anastellin impacts on the processing of extracellular matrix fibronectin and stimulates release of cytokines from coronary artery smooth muscle cells.
Scientific Reports,
12(1), Article 22051.
https://doi.org/10.1038/s41598-022-26359-9
Harwood, S. L., Diep, K., Nielsen, N. S., Jensen, K. T. & Enghild, J. J. (2022).
The conformational change of the protease inhibitor α2-macroglobulin is triggered by the retraction of the cleaved bait region from a central channel.
Journal of Biological Chemistry,
298(8), Article 102230.
https://doi.org/10.1016/j.jbc.2022.102230
Hartmann, S.
, Ling, M., Dreyer, L. S. A., Zipori, A.
, Finster, K., Grawe, S.
, Jensen, L. Z., Borck, S., Reicher, N., Niedermeier, D.
, Jones, N. C., Hoffmann, S. V., Wex, H., Rudich, Y.
, Boesen, T. & Santl-Temkiv, T. (2022).
Structure and Protein-Protein Interactions of Ice Nucleation Proteins Drive Their Activity.
Frontiers in Microbiology,
13, Article 872306.
https://doi.org/10.3389/fmicb.2022.872306
Hansen, E. K. B., Fredsøe, J. H., Okholm, T. L. H., Ulhøi, B. P., Klingenberg, S., Jensen, J. B., Kjems, J., Bouchelouche, K., Borre, M., Damgaard, C. K., Pedersen, J. S., Kristensen, L. S. & Sørensen, K. D. (2022).
The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer.
Genome Medicine,
14(1), Article 8.
https://doi.org/10.1186/s13073-021-01009-3
Hansen, N. P., Kristensen, T., Johansen, M., Wiking, L., Poulsen, N. A., Hellwing, A. L. F., Foldager, L., Jensen, S. K., Larsen, L. B. & Weisbjerg, M. R. (2022).
Effects on feed intake, milk production, and methane emission in dairy cows fed silage or fresh grass with concentrate or fresh grass harvested at early or late maturity stage without concentrate.
Journal of Dairy Science,
105(10), 8036-8053.
https://doi.org/10.3168/jds.2022-21885