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Department of Molecular Biology and Genetics

Neurobiology

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.

Groups at DANDRITE encompass ambitious research programs that include:

Molecular and cellular mechanisms of memory
Effort-based decision making
Neuronal development and stem cells
Motor control
Brain processing of vision
Neurological and neurodegenerative diseases
Psychiatric disorders
Neurotrophic receptors, sorting
Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

List of staff and students in the research group

Group leaders

Professors

Associate Professors

Tenure Track Assistant Professor

Gilles Claude Vanwalleghem

Professor

Associate Professors

Tenure Track Assistant Professor

Peer-reviewed publications

Sort by: Date | Author | Title

Lazarov, E., Hillebrand, M., Schröder, S., Ternka, K., Hofhuis, J., Ohlenbusch, A., Barrantes-Freer, A., Pardo, L. A., Fruergaard, M. U., Nissen, P., Brockmann, K., Gärtner, J. & Rosewich, H. (2020). Comparative analysis of alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism ATP1A3 mutations reveals functional deficits, which do not correlate with disease severity. Neurobiology of Disease, 143, Article 105012. https://doi.org/10.1016/j.nbd.2020.105012

Laursen, M., Bublitz, M., Moncoq, K., Olesen, C., Møller, J. V., Young, H., Nissen, P. & Morth, J. P. (2009). Cyclopiazonic Acid Is Complexed to a Divalent Metal Ion When Bound to the Sarcoplasmic Reticulum Ca2+-ATPase. Journal of Biological Chemistry, 284(20), 13513-13518.

Laursen, M., Yatime, L., Nissen, P. & Fedosova, N. (2013). Crystal structure of the high-affinity Na+,K+-ATPase–ouabain complex with Mg2+ bound in the cation binding site. Proceedings of the National Academy of Sciences (PNAS), 110(27), 10958–10963. https://doi.org/10.1073/pnas.1222308110

Laursen, M., Gregersen, J. L., Yatime, L., Nissen, P. & Fedosova, N. (2015). Structures and characterization of digoxin- and bufalin-bound Na⁺,K⁺-ATPase compared with the ouabain-bound complex. Proceedings of the National Academy of Sciences (PNAS), 112(6), 1755-1760. https://doi.org/10.1073/pnas.1422997112

Larsen, S. T., Dannersø, J. K., Nielsen, C. J. F., Poulsen, L. R., Palmgren, M. & Nissen, P. (2024). Conserved N-terminal Regulation of the ACA8 Calcium Pump with Two Calmodulin Binding Sites. Journal of Molecular Biology, 436(20), Article 168747. https://doi.org/10.1016/j.jmb.2024.168747

Kurihara, Y., Ekimoto, T., Gordon, C. T., Uchijima, Y., Sugiyama, R., Kitazawa, T., Iwase, A., Kotani, R., Asai, R., Pingault, V., Ikeguchi, M., Amiel, J. & Kurihara, H. (2023). Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding. Journal of Clinical Investigation, 133(4), Article e151536. https://doi.org/10.1172/JCI151536

Kristensen, O., Reshetnikova, L., Nissen, P., Siboska, G., Thirup, S. & Nyborg, J. (1996). Isolation, crystallization and X-ray analysis of the quaternary complex of Phe-tRNA(Phe), EF-Tu, a GTP analog and kirromycin. FEBS Letters, 399(1-2), 59-62.

Krintel, C., Dorosz, J., Larsen, A. H., Thorsen, T. S., Venskutonytė, R., Mirza, O., Gajhede, M., Boesen, T. & Kastrup, J. S. (2021). Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2. FEBS journal, 288(3), 995-1007. https://doi.org/10.1111/febs.15455

Krauth, N., Khalil, V., Jariwala, M., Mermet-Joret, N., Vestergaard, A. K., Capogna, M. & Nabavi, S. (2020). TRACE: An Unbiased Method to Permanently Tag Transiently Activated Inputs. Frontiers in Cellular Neuroscience, 14, Article 114. https://doi.org/10.3389/fncel.2020.00114

Kowalski, A., Betzer, C., Larsen, S. T., Gregersen, E., Newcombe, E. A., Bermejo, M. C., Bendtsen, V. W., Diemer, J., Ernstsen, C. V., Jain, S., Bou, A. E., Langkilde, A. E., Nejsum, L. N., Klipp, E., Edwards, R., Kragelund, B. B., Jensen, P. H. & Nissen, P. (2023). Monomeric α-synuclein activates the plasma membrane calcium pump. The EMBO Journal, 42(23), Article e111122. https://doi.org/10.15252/embj.2022111122

Kotsubei, A., Gorgel, M., Morth, J. P., Nissen, P. & Andersen, J. L. (2013). Probing determinants of cyclopiazonic acid sensitivity of bacterial Ca(2+) -ATPases. FEBS journal, 280(21), 5441–5449. https://doi.org/10.1111/febs.12310

Kol, S., Braun, C., Thiel, G., Doyle, D. A., Sundström, M., Gourdon, P. & Nissen, P. (2013). Heterologous expression and purification of an active human TRPV3 ion channel. FEBS journal, 280(23), 6010–6021. https://doi.org/10.1111/febs.12520

Displaying results 157 to 168 out of 312

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Revised 13.11.2025

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Helene Eriksen