Dahl, L. D., Corydon, T. J., Ränkel, L., Nielsen, K. M., Füchtbauer, E.-M. & Knudsen, C. R. (2014).
An eEF1A1 truncation encoded by PTI-1 exerts its oncogenic effect inside the nucleus.
Cancer Cell International,
14(17), 1-11.
https://doi.org/10.1186/1475-2867-14-17
Nielsen, M. M., Theler, D.
, Vang, S., Sudzina, F.
, Hedegaard, J., Nordentoft, I. K., Ørntoft, T. F., Lund, A.
& Pedersen, J. S. (2014).
Identification of expressed and conserved human noncoding RNAs.
RNA,
20(2), 236-251.
https://doi.org/10.1261/rna.038927.113
Lorenzen, N., Nielsen, S. B., Buell, A. K.
, Kaspersen, J. D., Arosio, P.
, Vad, B. S., Paslawski, W., Christiansen, G., Valnickova Hansen, Z., Andreasen, M., Enghild, J. J., Pedersen, J. S., Dobson, C. M., Knowles, T. P. J.
& Otzen, D. (2014).
The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation.
Journal of the American Chemical Society,
136(10), 3859-3868.
https://doi.org/10.1021/ja411577t
Debrabant, B.
, Soerensen, M., Flachsbart, F., Dato, S., Mengel-From, J.
, Stevnsner, T., Bohr, V. A., Kruse, T. A., Schreiber, S., Nebel, A., Christensen, K., Tan, Q. & Christiansen, L. (2014).
Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis.
European Journal of Human Genetics,
22, 1131-1136.
https://doi.org/10.1038/ejhg.2013.299
Maolanon, N. N.
, Blaise, M., Sørensen, K. K., Thygesen, M. B., Cló, E., Sullivan, J. T., Ronson, C. W.
, Stougaard, J., Blixt, K. O. & Jensen, K. J. (2014).
Lipochitin Oligosaccharides Immobilized through Oximes in Glycan Microarrays Bind LysM Proteins.
ChemBioChem,
15(3), 425-434.
https://doi.org/10.1002/cbic.201300520
Kronqvist, N., Otikovs, M., Chmyrov, V., Chen, G., Andersson, M., Nordling, K., Landreh, M., Sarr, M., Jörnvall, H., Wennmalm, S., Widengren, J., Meng, Q., Rising, A.
, Otzen, D., Knight, S. D., Jaudzems, K. & Johansson, J. (2014).
Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation.
Nature Communications,
5, Artikel 3254.
https://doi.org/10.1038/ncomms4254
Iešmantavičius, V., Dogan, J., Jemth, P., Teilum, K.
& Kjærgaard, M. (2014).
Helical propensity in an intrinsically disordered protein accelerates ligand binding.
Angewandte Chemie International Edition,
53(6), 1548-51.
https://doi.org/10.1002/anie.201307712
Wong, J. E. M. M., Alsarraf, H. M. A. B., Kaspersen, J. D., Pedersen, J. S., Stougaard, J., Thirup, S. S. & Blaise, M. (2014).
Cooperative binding of LysM domains determines the carbohydrate affinity of a bacterial endopeptidase protein.
FEBS journal,
281(4), 1196-1208.
https://doi.org/10.1111/febs.12698
Mostowy, S., Bi, E.
, Füchtbauer, E.-M., Goryachev, A. B., Montagna, C., Nagata, K.-I., Trimble, W. S., Werner, H. B., Yao, X., Zieger, B. & Spiliotis, E. T. (2014).
Highlight: The 5th International Workshop on Septin Biology.
Biological Chemistry,
395(2), 119-121.
https://doi.org/10.1515/hsz-2013-0291
Andersen, J. L., Schrøder, T. J., Christensen, S.
, Strandbygård, D. J., Pallesen, L. T., Garcia Alai, M. M., Lindberg, S., Langgård, M., Eskildsen, J. C., David, L., Tagmose, L., Simonsen, K. B., Maltas, P. J., Rønn, L. C. B., de Jong, I. E. M., Malik, I. J., Egebjerg, J., Karlsson, J. J., Uppalanchi, S.
... Thirup, S. (2014).
Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex.
Acta Crystallographica. Section D: Biological Crystallography,
70(Part 2), 451-460.
https://doi.org/10.1107/S1399004713030149
Dam, S., Dyrlund, T. F., Ussatjuk, A., Jochimsen, B., Nielsen, K., Goffard, N.
, Ventosa, M. A. L., Lorentzen, A. M.
, Gupta, V., Andersen, S. U., Enghild, J. J., Ronson, C. W., Roepstorff, P.
& Stougaard, J. (2014).
Proteome reference maps of the Lotus japonicus nodule and root.
Proteomics,
14(2-3), 230-240.
https://doi.org/10.1002/pmic.201300353
Paszota, P., Escalante-Perez, M.
, Thomsen, L. R., Risør, M. W., Dembski, A.
, Sanglas, L., Nielsen, T. A., Karring, H., Thøgersen, I. B., Hedrich, R.
, Enghild, J. J., Kreuzer, I.
& Sanggaard, K. W. (2014).
Secreted major Venus flytrap chitinase enables digestion of Arthropod prey.
BBA General Subjects,
1844(2), 374–383.
https://doi.org/10.1016/j.bbapap.2013.11.009
Lorenzen, N., Lemminger, L., Pedersen, J. N., Nielsen, S. B. & Otzen, D. (2014).
The N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranes.
FEBS Letters,
588(3), 497-502.
https://doi.org/10.1016/j.febslet.2013.12.015
Edhager, A. V., Stenbroen, V., Nielsen, N. S., Bross, P., Olsen, R. K. J., Gregersen, N. & Palmfeldt, J. (2014).
Proteomic investigation of cultivated fibroblasts from patients with mitochondrial short-chain acyl-CoA dehydrogenase deficiency.
Molecular Genetics and Metabolism,
111(3), 360-368.
https://doi.org/10.1016/j.ymgme.2014.01.007
Li, S., Besenbacher, S., Li, Y., Kristiansen, K., Grarup, N., Albrechtsen, A., Sparsø, T. H., Korneliussen, T. S., Hansen, T., Wang, J., Nielsen, R., Pedersen, O.
, Bolund, L. & Schierup, M. H. (2014).
Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population.
European Journal of Human Genetics.
https://doi.org/10.1038/ejhg.2013.282
Mikkelsen, J. H., Resch, Z. T., Kalra, B., Savjani, G., Kumar, A., Conover, C. A.
& Oxvig, C. (2014).
Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity.
OncoTarget,
5(4), 1014-1025.
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=1675
Pedersen, B. P., Ifrim, G., Liboriussen, P., Axelsen, K. B., Palmgren, M. G.
, Nissen, P., Wiuf, C. H.
& Pedersen, C. N. S. (2014).
Large Scale Identification and Categorization of Protein Sequences Using Structured Logistic Regression.
P L o S One,
9(1), Artikel e85139.
https://doi.org/10.1371/journal.pone.0085139
Larsen, J. V., Hermey, G., Sørensen, E. S., Prabakaran, T., Christensen, E. I., Gliemann, J., Madsen, P. & Petersen, C. M. (2014).
Human sorCS1 binds sortilin and hampers its cellular functions.
Biochemical Journal,
457(2), 277–288.
https://doi.org/10.1042/BJ20130386
Hofbauer, S.
, Gysel, K., Bellei, M., Hagmüller, A., Schaffner, I., Mlynek, G., Kostan, J., Pirker, K. F., Daims, H., Furtmüller, P. G., Battistuzzi, G., Djinović-Carugo, K. & Obinger, C. (2014).
Manipulating conserved heme cavity residues of chlorite dismutase: effect on structure, redox chemistry, and reactivity.
Biochemistry,
53(1), 77-89.
https://doi.org/10.1021/bi401042z
Wittenborn, T. R., Larsen, E. K. U., Nielsen, T., Rydtoft, L. M., Hansen, L., Nygaard, J. V., Vorup-Jensen, T., Kjems, J., Horsman, M. R. & Nielsen, N. C. (2014).
Accumulation of nano-sized particles in a murine model of angiogenesis.
Biochemical and Biophysical Research Communications,
443(2), 470-6.
https://doi.org/10.1016/j.bbrc.2013.11.127
Proszek, J.
, Roy, A., Jakobsen, A.-K., Hougaard, R. F., Knudsen, B. R. & Stougaard, M. (2014).
Topoisomerase I as a Biomarker: Detection of Activity at the Single Molecule Level.
Sensors,
14(1), 1195-1207.
https://doi.org/10.3390/s140101195
Nielsen, C., Kjems, J., Sorensen, K. R., Engelholm, L. H. & Behrendt, N. (2014).
Advances in targeted delivery of small interfering RNA using simple bioconjugates.
Expert Opinion on Drug Delivery,
11(5), 791-822.
https://doi.org/10.1517/17425247.2014.896898
Menéndez, C., Adrados, I., Fernández-Barral, A., Jiménez, B., Flores, J. M., Cañamero, M.
, Füchtbauer, E.-M., Beermann, F. & Palmero, I. (2014).
Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1.
Pigment Cell & Melanoma Research,
27(4), 674-677.
https://doi.org/10.1111/pcmr.12241
Nawroth, I., Mueller, F., Basyuk, E.
, Beerens, N., Rahbek, U. L., Darzacq, X., Bertrand, E.
, Kjems, J. & Schmidt, U. (2014).
Stable assembly of HIV-1 export complexes occurs cotranscriptionally.
RNA,
20(1), 1-8.
https://doi.org/10.1261/rna.038182.113
Lyons, J. A., Parker, J. L., Solcan, N., Brinth, A., Li, D., Shah, S. T., Caffrey, M. & Newstead, S. (2014).
Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters.
E M B O Reports,
15(8), 886-893.
https://doi.org/10.15252/embr.201338403
Schrøder, T. J., Christensen, S., Lindberg, S., Langgård, M., David, L., Maltas, P. J., Eskildsen, J., Jacobsen, J., Tagmose, L., Simonsen, K. B., Biilmann Rønn, L. C., de Jong, I. E. M., Malik, I. J., Karlsson, J.-J., Bundgaard, C., Egebjerg, J., Stavenhagen, J. B.
, Strandbygård, D., Thirup, S. S. ... Watson, S. P. (2014).
The identification of AF38469: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin.
Bioorganic & Medicinal Chemistry Letters,
24(1), 177-180.
https://doi.org/10.1016/j.bmcl.2013.11.046
Aamann, M. D., Hvitby, C. P., Popuri, V., Muftuoglu, M.
, Lemminger, L. P. B., K. Skeby , C.
, Keijzers, G., Ahn, B., Bjørås , M., Bohr, V.
& Stevnsner, T. V. (2014).
Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity.
Mechanisms of Ageing and Development,
135, 1-14.
https://doi.org/10.1016/j.mad.2013.12.008
Poulsen, R. H., Rasmussen, J. T., Bøtker, H. E., Wæhrens, L. N., Falborg, L., Heegaard, C. W. & Rehling, M. (2014).
Imaging the myocardium at risk with (99m)Tc-lactadherin administered after reperfusion in a porcine model.
Nuclear Medicine and Biology,
41(1), 114-119.
https://doi.org/10.1016/j.nucmedbio.2013.09.004
Zhao, B.
, Xu, P., Jiang, L., Paaske, B.
, Kromann-Hansen, T., Jensen, J. K., Sørensen, H. P., Liu, Z., Nielsen, J. T., Christensen, A., Hosseini, M., Sørensen, K. K.
, Nielsen, N. C., Jensen, K. J., Huang, M.
& Andreasen, P. A. (2014).
A cyclic peptidic serine protease inhibitor: increasing affinity by increasing Peptide flexibility.
PLOS ONE,
9(12), Artikel e115872.
https://doi.org/10.1371/journal.pone.0115872
Sørensen, H. J.
, Foldager, L., Røge, R., Pristed, S. G., Andreasen, J. T. & Nielsen, J. (2014).
An association between autumn birth and clozapine treatment in patients with schizophrenia: A population-based analysis.
Nordic Journal of Psychiatry,
68(6), 428-432.
https://doi.org/10.3109/08039488.2013.854408
Yang, C., Nilsson, L., Cheema, M. U., Wang, Y., Frøkiær, J., Gao, S., Kjems, J. & Nørregaard, R. (2014).
Chitosan/siRNA Nanoparticles Targeting Cyclooxygenase Type 2 Attenuate Unilateral Ureteral Obstruction-induced Kidney Injury in Mice.
Theranostics,
5(2), 110-123.
https://doi.org/10.7150/thno.9717
Andersson, M.
, Mattle, D., Sitsel, O., Klymchuk, T., Nielsen, A. M., Møller, L. B., White, S. H.
, Nissen, P. & Gourdon, P. (2014).
Copper-transporting P-type ATPases use a unique ion-release pathway.
Nature Structural and Molecular Biology,
21, 43-48.
https://doi.org/10.1038/nsmb.2721
Roy, A., Tesauro, C., Frøhlich, R.
, Hede, M. S., Nielsen, M. J., Kjeldsen, E., Bonven, B., Stougaard, M., Gromova, I.
& Knudsen, B. R. (2014).
Decreased camptothecin sensitivity of the stem-cell-like fraction of caco2 cells correlates with an altered phosphorylation pattern of topoisomerase I.
PLOS ONE,
9(6), Artikel e99628.
https://doi.org/10.1371/journal.pone.0099628
Liu, Y., Lucas-Hahn, A., Petersen, B.
, Li, R., Hassel, P., Ziegler, M.
, Li, J., Larsen, K. E., Niemann, H.
& Callesen, H. (2014).
Developmental competence of cloned porcine embryos produced with different cloning procedures.
Reproduction, Fertility and Development,
26(1), 123. Artikel 18.
https://doi.org/10.1071/RDv26n1abs
Cai, Z., Liu, H., He, Q., Pu, M., Lai, J., Li, X. & Jin, W. (2014).
Differential genome evolution and speciation of Coix lacryma-jobi L. and Coix aquatica Roxb. hybrid guangxi revealed by repetitive sequence analysis and fine karyotyping.
B M C Genomics,
15, 1025.
https://doi.org/10.1186/1471-2164-15-1025
Cheema, M. U., Damkier, H. H.
, Nielsen, J., Poulsen, E. T., Enghild, J. J., Fenton, R. A. & Praetorius, J. (2014).
Distal Renal Tubules Are Deficient in Aggresome Formation and Autophagy upon Aldosterone Administration.
PLOS ONE,
9(7), e101258.
https://doi.org/10.1371/journal.pone.0101258