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Peer-review'ede publikationer ved MBG - 2025

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Rasmussen, C. L. M., Frederiksen, S. F., Heegaard, C. W., Thomsen, M. S., Hede, E., Laczek, B., Körbelin, J., Wüstner, D., Thomsen, L. B., Schwaninger, M., Jensen, O. N., Moos, T. & Burkhart, A. (2025). Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2. Fluids and Barriers of the CNS, 22(1), Artikel 13. https://doi.org/10.1186/s12987-025-00621-4

Qin, Q., Wei, P., Usman, S., Ahamefule, C. S., Jin, C., Wang, B., Yan, K., van Aalten, D. M. F. & Fang, W. (2025). Gfa1 (glutamine fructose-6-phosphate aminotransferase) is essential for Aspergillus fumigatus growth and virulence. BMC Biology, 23(1), Artikel 80. https://doi.org/10.1186/s12915-025-02184-0

Bryzek, D., Gasiorek, A., Kowalczyk, D., Santocki, M., Ciaston, I., Dobosz, E., Kolaczkowska, E., Kjøge, K., Kantyka, T., Lech, M., Potempa, B., Enghild, J. J., Potempa, J. & Koziel, J. (2025). Non-classical neutrophil extracellular traps induced by PAR2-signaling proteases. Cell Death & Disease, 16(1), 109. Artikel 109. https://doi.org/10.1038/s41419-025-07428-z

Thorsen, T. S., Kulkarni, Y., Sykes, D. A., Bøggild, A., Drace, T., Hompluem, P., Iliopoulos-Tsoutsouvas, C., Nikas, S. P., Daver, H., Makriyannis, A., Nissen, P., Gajhede, M., Veprintsev, D. B., Boesen, T., Kastrup, J. S. & Gloriam, D. E. (2025). Structural basis of THC analog activity at the Cannabinoid 1 receptor. Nature Communications, 16(1), Artikel 486. https://doi.org/10.1038/s41467-024-55808-4

Nowak, J. S., Olesen, S., Tian, P., Bærentsen, R. L., Brodersen, D. E. & Otzen, D. E. (2025). Role of electrostatics in cold adaptation: A comparative study of eury- and stenopsychrophilic triose phosphate isomerase. B B A - Proteins and Proteomics, 1873(4), Artikel 141072. https://doi.org/10.1016/j.bbapap.2025.141072

Horsdal, H. T., Albiñana, C., Zhu, Z., Boelt, S. G., Borbye-Lorenzen, N., Cohen, A. S., Skogstrand, K., Melgaard, L., MacSween, N. J., Thorbek, M. J., Plana-Ripoll, O., Petersen, L. V., Bulik, C. M., B Rglum, A. D., Mors, O., Nordentoft, M., Werge, T., Moen, G.-H., D'Urso, S. ... McGrath, J. J. (2025). Convergent evidence linking neonatal vitamin D status and risk of neurodevelopmental disorders: a Danish case-cohort study. The Lancet Psychiatry, 12(6), 410-420. https://doi.org/10.1016/S2215-0366(25)00099-9

Cabrejas-Olalla, A., Jørgensen, F. G., Cheng, J. Y., Kjærgaard, P. C., Schierup, M. H., Mailund, T. & Athanasiadis, G. (2025). Genetic predictions of eye and hair colour in the Danish population. Forensic Science International: Genetics, 78, Artikel 103267. https://doi.org/10.1016/j.fsigen.2025.103267

Andersen, H. H., Andersen, M. K., Bossow, K. A., Vestergaard, A. L., Bor, P. & Larsen, A. (2025). High-dose vitamin D supplementation in pregnancy ameliorates obesity-induced increase in maternal IL-1β level without affecting obesity-induced increase in IL-6 and MCP. The Journal of Steroid Biochemistry and Molecular Biology, 250, Artikel 106742. https://doi.org/10.1016/j.jsbmb.2025.106742

McLain, A., Kowalczyk, A., Baran-Rachwalska, P., Sutera, F. M., Robertson, L. J., Nielsen, N. S., Enghild, J. J., Cobice, D., Bonelli, F., Barbaro, V., Ferrari, S., Patterson, B., Moore, L., Marshall, J., Nesbit, M. A. & Moore, T. (2025). TGFBI R124H mutant allele silencing in granular corneal dystrophy type 2 using topical siRNA delivery. Journal of Controlled Release, 382, Artikel 113681. https://doi.org/10.1016/j.jconrel.2025.113681

Staehr, C., Login, H., Melnikova, E., Bakun, M., Ziemlinska, E., Kisiswa, L., Berenji Ardestani, S., Nolte, S. S., Beck, H. C., Hansen, L. M. B., Postnov, D., Verkhratsky, A., Malik, A. R., Nykjær, A. & Matchkov, V. (2025). SorCS2 Is Important for Astrocytic Function in Neurovascular Signaling. Acta Physiologica (Print), 241(6). https://doi.org/10.1111/apha.70052

Kofod Petersen, A., Forgie, A., Villesen, P. & Staun Larsen, L. (2025). 3D dental similarity quantification in forensic odontology identification. Forensic Science International, 370, Artikel 112462. https://doi.org/10.1016/j.forsciint.2025.112462

Bruhn, D., Griffin, K. L. & Møller, I. M. (2025). Importance of Timing of Dark Acclimation for Estimating Light Inhibition of Leaf Respiratory CO₂ Efflux. Plant, Cell & Environment, 48(5), 3151-3158. https://doi.org/10.1111/pce.15335

Midtgaard, S. R., Hansen, M. S., Drachmann, N., Geng, X., Blans, K. I. M., Møbjerg, M. M. F., Frølund, A. F., Rasmussen, J. T. & Ostenfeld, M. S. (2025). Industrial Scale Production and Characterization of a Whey Fraction Enriched in Extracellular Vesicle Material. Journal of Extracellular Biology, 4(5), Artikel e70044. https://doi.org/10.1002/jex2.70044

Nowak, J. S., Kruuse, N., Rasmussen, H. Ø., Tian, P., Astono, J., Schultz-Nielsen, S., Thøgersen, M. S., Stougaard, P., Pedersen, J. S. & Otzen, D. E. (2025). Quaternary stabilization of a GH2 β-galactosidase from the psychrophile A. ikkensis, a flexible and unstable dimeric enzyme. Protein Science, 34(5). https://doi.org/10.1002/pro.70141

Simonsen, B., Rübsam, H., Kolte, M. V., Larsen, M. M., Krönauer, C., Gysel, K., Laursen, M., Feng, F., Kaya, G., Oldroyd, G. E. D., Stougaard, J., Fort, S., Radutoiu, S. & Andersen, K. R. (2025). The Medicago truncatula LYR4 intracellular domain serves as a scaffold in immunity signaling independent of its phosphorylation activity. New Phytologist, 246(4), 1423-1431. https://doi.org/10.1111/nph.70067

Christiansen, G. B., Petersen, L. V., Chatwin, H., Yilmaz, Z., Schendel, D., Bulik, C. M., Grove, J., Brikell, I., Semark, B. D., Holde, K., Abdulkadir, M., Hübel, C., Albiñana, C., Vilhjálmsson, B. J., Børglum, A. D., Demontis, D., Mortensen, P. B. & Larsen, J. T. (2025). The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder. Molecular Psychiatry, 30(5), 2127-2136. Artikel 132. https://doi.org/10.1038/s41380-024-02825-w

Andersen, C. G., Bavnhøj, L., Brag, S., Bohush, A., Chrenková, A., Driller, J. H. & Pedersen, B. P. (2025). Comparative analysis of STP6 and STP10 unravels molecular selectivity in sugar transport proteins. Proceedings of the National Academy of Sciences of the United States of America, 122(17), Artikel e2417370122. https://doi.org/10.1073/pnas.2417370122

Riedelbauch, S., Masser, S., Fasching, S., Lin, S. Y., Salgania, H. K., Aarup, M., Ebert, A., Jeske, M., Levine, M. T., Stelzl, U. & Andersen, P. (2025). Recurrent innovation of protein-protein interactions in the Drosophila piRNA pathway. EMBO Journal, Artikel 98. Advance online publication. https://doi.org/10.1038/s44318-025-00439-8

Schulz, L., Ung, K. L., Zuzic, L., Koutnik-Abele, S., Schiøtt, B., Stokes, D. L., Pedersen, B. P. & Hammes, U. Z. (2025). Transport of phenoxyacetic acid herbicides by PIN-FORMED auxin transporters. Nature Plants. Advance online publication. https://doi.org/10.1038/s41477-025-01984-0

Mirab, F., Pirhaghi, M., Otzen, D. E. & Saboury, A. A. (2025). Parkinson's disease and gut microbiota metabolites: The dual impact of vitamins and functional amyloids. B B A - Molecular Basis of Disease, 167862. Advance online publication. https://doi.org/10.1016/j.bbadis.2025.167862

Auxillos, J., Stigliani, A., Vaagensø, C. S., Garland, W., Niazi, A. M., Valen, E., Jensen, T. H. & Sandelin, A. (2025). True length of diverse capped RNA sequencing (TLDR-seq): 5'-3'-end sequencing of capped RNAs regardless of 3'-end status. Nucleic Acids Research, 53(6), Artikel gkaf240. https://doi.org/10.1093/nar/gkaf240

Digel, L., Justesen, M. L., Madsen, N. S., Fransaert, N., Wouters, K., Bonné, R., Plum-Jensen, L. E., Marshall, I. P. G., Jensen, P. B., Nicolas-Asselineau, L., Drace, T., Bøggild, A., Hansen, J. L., Schramm, A., Bøjesen, E. D., Nielsen, L. P., Manca, J. V. & Boesen, T. (2025). Comparison of cable bacteria genera reveals details of their conduction machinery. EMBO Reports, 26(7), 1749-1767. Artikel 13699. https://doi.org/10.1038/s44319-025-00387-8

Basse Hansen, S., Flygaard, R. K., Kjaergaard, M. & Nissen, P. (2025). Structure of the [Ca]E2P intermediate of Ca²⁺-ATPase 1 from Listeria monocytogenes. EMBO Reports, 26(7), 1709-1723. Artikel eadd9742. https://doi.org/10.1038/s44319-025-00392-x

PGC TS Working Group & 23andMe Research Team (2025). Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders. Biological Psychiatry, 97(7), 743-752. https://doi.org/10.1016/j.biopsych.2024.07.025

Hong, Z., Tesic, N. & Bofill-De Ros, X. (2025). Analysis of Processing, Post-Maturation, and By-Products of shRNA in Gene and Cell Therapy Applications. Methods and Protocols, 8(2), Artikel 38. https://doi.org/10.3390/mps8020038

Mundy, J., Hall, A. S. M., Agerbo, E., Albiñana, C., Steinbach, J., Vilhjálmsson, B. J., Østergaard, S. D. & Musliner, K. L. (2025). Genetic Confounding of the Association Between Age at First Hormonal Contraception and Depression. Acta Psychiatrica Scandinavica, 151(4), 529-536. https://doi.org/10.1111/acps.13774

Li, Z., Xue, Y., Duan, Y., Yuan, W., Chen, C., Shi, S., Su, X. C., Kisiswa, L., Fan, J. S. & Lin, Z. (2025). Heterotypic interactions among members of the death domain superfamily with implications for p75^NTR-mediated co-signaling. International Journal of Biological Macromolecules, 304(Part 1), Artikel 140791. https://doi.org/10.1016/j.ijbiomac.2025.140791

Dardani, C., Robinson, J. W., Jones, H. J., Rai, D., Stergiakouli, E., Grove, J., Gardner, R., McIntosh, A. M., Havdahl, A., Hemani, G., Davey Smith, G., Richardson, T. G., Gaunt, T. R. & Khandaker, G. M. (2025). Immunological drivers and potential novel drug targets for major psychiatric, neurodevelopmental, and neurodegenerative conditions. Molecular Psychiatry, Artikel e1004092. Advance online publication. https://doi.org/10.1038/s41380-025-03032-x

Bruhn, D., Fan, Y., Griffin, K. L., Cowan-Turner, D., Scafaro, A. P., Møller, I. M. & Atkin, O. K. (2025). Importance of the leaf respiratory quotient. Physiologia Plantarum, 177(2), Artikel e70235. https://doi.org/10.1111/ppl.70235

van den Berg, J. & Zeller, P. (2025). Shining a light on cell biology of the nucleus with single-cell sequencing. Current Opinion in Cell Biology, 93, Artikel 102468. https://doi.org/10.1016/j.ceb.2025.102468

Fraifeld, V. & Rattan, S. (2025). Stem cells in ageing and longevity: a new section in Biogerontology. Biogerontology, 26, Artikel 69. https://doi.org/10.1007/s10522-025-10217-y

Conover, C. A. & Oxvig, C. (2025). The IGF System and Aging. Endocrine Reviews, 46(2), 214-223. https://doi.org/10.1210/endrev/bnae029

Marzookian, K., Aliakbari, F., Hourfar, H., Sabouni, F., Otzen, D. E. & Morshedi, D. (2025). The neuroprotective effect of human umbilical cord MSCs-derived secretome against α-synuclein aggregates on the blood-brain barrier. International Journal of Biological Macromolecules, 304(Part 1), Artikel 140387. https://doi.org/10.1016/j.ijbiomac.2025.140387

Shah, A., Zhang, X., Snee, M., Lockhart-Cairns, M. P., Levy, C. W., Jowitt, T. A., Birchenough, H. L., Dean, L., Collins, R., Dodd, R. J., Roberts, A. R. E., Enghild, J. J., Mantovani, A., Fontana, J., Baldock, C., Inforzato, A., Richter, R. P. & Day, A. J. (2025). The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-α-inhibitor regulate crosslinking of the hyaluronan matrix. Matrix biology : journal of the International Society for Matrix Biology, 136, 52-68. https://doi.org/10.1016/j.matbio.2025.01.002

O’Leary, E., Jiang, Y., Kristensen, L. S., Hansen, T. B. & Kjems, J. (2025). The therapeutic potential of circular RNAs. Nature Reviews Genetics, 26(4), 230-244. Artikel 2629. https://doi.org/10.1038/s41576-024-00806-x

André, A. A. M., Rehnberg, N., Garg, A. & Kjærgaard, M. (2025). Toward Design Principles for Biomolecular Condensates for Metabolic Pathways. Advanced Biology. Advance online publication. https://doi.org/10.1002/adbi.202400672

Hu, Q., Sitsel, O., Bågenholm, V., Grønberg, C., Lyu, P., Pii Svane, A. S., Andersen, K. R., Laursen, N. S., Meloni, G., Nissen, P., Juhl, D. W., Nielsen, J. T., Nielsen, N. C. & Gourdon, P. (2025). Transition metal transporting P-type ATPases: terminal metal-binding domains serve as sensors for autoinhibitory tails. FEBS journal, 292(7), 1654-1674. https://doi.org/10.1111/febs.17330

23andMe Research Team (2025). Genomics yields biological and phenotypic insights into bipolar disorder. Nature, 639, 968-975. Artikel 2417. https://doi.org/10.1038/s41586-024-08468-9

Ghouse, J., Ahlberg, G., Albertsen Rand, S., Salling Olesen, M., Vilhjalmsson, B., Stender, S. & Bundgaard, H. (2025). Within-person stability of lipoprotein(a) concentration. European Heart Journal, 46(12), 1159-1161. https://doi.org/10.1093/eurheartj/ehae652

Bendtsen, M. K., Nowak, J. S., Paiva, P., López Hernández, M., Ferreira, P., Pedersen, J. S., Bekker, N. S., Viezzi, E., Bisiak, F., Brodersen, D. E., Pedersen, L. H., Zervas, A., Fernandes, P. A., Ramos, M. J., Stougaard, P., Thøgersen, M. S. & Otzen, D. E. (2025). Cold-Active Starch-Degrading Enzymes from a Cold and Alkaline Greenland Environment: Role of Ca²⁺ Ions and Conformational Dynamics in Psychrophilicity. Biomolecules, 15(3), Artikel 415. https://doi.org/10.3390/biom15030415

Kriebisch, C. M. E., Bantysh, O., Baranda Pellejero, L., Belluati, A., Bertosin, E., Dai, K., de Roy, M., Fu, H., Galvanetto, N., Gibbs, J. M., Gomez, S. S., Granatelli, G., Griffo, A., Guix, M., Gurdap, C. O., Harth-Kitzerow, J., Haugerud, I. S., Häfner, G., Jaiswal, P. ... Boekhoven, J. (2025). A roadmap toward the synthesis of life. Chem, 11(3), Artikel 102399. https://doi.org/10.1016/j.chempr.2024.102399

Simonsen, B., Rübsam, H., Kolte, M. V., Larsen, M. M., Krönauer, C., Gysel, K., Laursen, M., Feng, F., Sezer, G., Oldroyd, G. E. D., Stougaard, J., Fort, S., Radutoiu, S. & Andersen, K. R. (2025). The Medicago truncatula LYR4 intracellular domain serves as a scaffold in immunity signaling independent of its phosphorylation activity. New Phytologist. Advance online publication. https://doi.org/10.1111/nph.70067

Olsen, W. P., Larsen, A.-K. K., Christensen, J. L., Malle, M. G. & Otzen, D. E. (2025). Investigating strategies for creating cross-linked amyloid fibril networks through branching of amyloid growth. Colloids and surfaces. B, Biointerfaces, 251, 114617. Artikel 114617. Advance online publication. https://doi.org/10.1016/j.colsurfb.2025.114617

Schlosser, A., Pilecki, B., Allen, C., Benest, A. V., Lynch, A. P., Hua, J., Ved, N., Blackley, Z., Andersen, T. L., Hennig, D., Graversen, J. H., Möller, S., Skallerup, S., Ormhøj, M., Lange, C., Agostini, H. T., Grauslund, J., Heegaard, S., Dacheva, I. ... Sorensen, G. L. (2025). Pharmacological blocking of microfibrillar-associated protein 4 reduces retinal neoangiogenesis and vascular leakage. Molecular Therapy, 33(3), 1048-1072. https://doi.org/10.1016/j.ymthe.2025.01.038

Singh, P., Kadam, N. Y., Panigrahi, R., Mehrotra, A., Upadhayay, K., Dey, M., Tyagi, A., Aquib, M., Nielsen, J., Kleijwegt, G., Singh, P., Sharma, A., Rao, A., Otzen, D. E., Kumar, A. & Sharma, D. (2025). Sulfamerazine as a Potential Modulator against α-Synuclein Aggregation and Associated Toxicity. ACS Chemical Neuroscience, 16(5), 880-894. https://doi.org/10.1021/acschemneuro.4c00803

Otzen, D. E., Peña-Díaz, S., Widmann, J., Daugberg, A. O. H., Zhang, Z., Jiang, Y., Mittal, C., Dueholm, M. K. D., Louros, N., Wang, H. & Javed, I. (2025). Interactions between pathological and functional amyloid: A match made in Heaven or Hell? Molecular Aspects of Medicine, 103, 101351. Artikel 101351. Advance online publication. https://doi.org/10.1016/j.mam.2025.101351

Kjeldsen, C. M. N. & Oxvig, C. (2025). The Proteinase PAPP-A has Deep Evolutionary Roots Outside of the IGF System. Genome Biology and Evolution, 17(3), Artikel evaf042. https://doi.org/10.1093/gbe/evaf042

Khachadourian, V., Arildskov, E. S., Grove, J., O'Reilly, P. F., Buxbaum, J. D., Reichenberg, A., Sandin, S., Croen, L. A., Schendel, D., Hansen, S. N. & Janecka, M. (2025). Familial confounding in the associations between maternal health and autism. Nature Medicine, 31(3), 996-1007. https://doi.org/10.1038/s41591-024-03479-5

Li, Q., Marietou, A., Andersen, F. F., Hosek, J., Scavenius, C., Zhang, J. & Schwab, C. (2025). In vitro investigations on the impact of fermented dairy constituents on fecal microbiota composition and fermentation activity. Microbiology Spectrum, 13(3), e0219324. https://doi.org/10.1128/spectrum.02193-24

Wang, J., Kidmose, R. T., Boegholm, N., Zacharia, N. K., Thomsen, M. B., Christensen, A., Malik, T., Lechtreck, K. & Lorentzen, E. (2025). Integrative in silico and biochemical analyses demonstrate direct Arl3-mediated ODA16 release from the intraflagellar transport machinery. Journal of Biological Chemistry, 301(3), Artikel 108237. https://doi.org/10.1016/j.jbc.2025.108237

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Peer-review'ede publikationer ved MBG - alle år

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Fraifeld, V. & Rattan, S. (2025). Stem cells in ageing and longevity: a new section in Biogerontology. Biogerontology, 26, Artikel 69. https://doi.org/10.1007/s10522-025-10217-y

Conover, C. A. & Oxvig, C. (2025). The IGF System and Aging. Endocrine Reviews, 46(2), 214-223. https://doi.org/10.1210/endrev/bnae029

23andMe Research Team (2025). Genomics yields biological and phenotypic insights into bipolar disorder. Nature, 639, 968-975. Artikel 2417. https://doi.org/10.1038/s41586-024-08468-9

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Revideret 02.12.2024

Lisbeth Heilesen