Evans, D. C. S., Khamas, A. B., Marcussen, L., Rasmussen, K. S., Klitgaard, J. K., Kallipolitis, B. H.
, Nielsen, J., Otzen, D. E., Leake, M. C.
& Meyer, R. L. (2023).
GFP fusions of Sec-routed extracellular proteins in Staphylococcus aureusreveal surface-associated coagulase in biofilms.
Microbial Cell,
10(7), 145-156.
https://doi.org/10.15698/mic2023.07.800
Singh, Y., Trautwein, C., Romani, J., Salker, M. S., Neckel, P. H., Fraccaroli, I., Abeditashi, M., Woerner, N., Admard, J., Dhariwal, A., Dueholm, M. K. D., Schäfer, K. H., Lang, F.
, Otzen, D. E., Lashuel, H. A., Riess, O. & Casadei, N. (2023).
Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease.
Molecular Neurodegeneration,
18(1), Artikel 44.
https://doi.org/10.1186/s13024-023-00628-1
Rolland, T., Cliquet, F., Anney, R. J. L., Moreau, C., Traut, N., Mathieu, A., Huguet, G.
, Duan, J., Warrier, V., Portalier, S., Dry, L., Leblond, C. S., Douard, E., Amsellem, F., Malesys, S., Maruani, A., Toro, R.
, Børglum, A. D., Grove, J. ... Bourgeron, T. (2023).
Phenotypic effects of genetic variants associated with autism.
Nature Medicine,
29(7), 1671-1680.
https://doi.org/10.1038/s41591-023-02408-2
Wang, X., Walker, A., Revez, J. A., Ni, G., Adams, M. J., McIntosh, A. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2023).
Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability.
American Journal of Human Genetics,
110(7), 1207-1215.
https://doi.org/10.1016/j.ajhg.2023.06.006
McRae, E. K. S., Rasmussen, H. Ø., Liu, J.
, Bøggild, A., Nguyen, M. T. A., Sampedro Vallina, N., Boesen, T., Pedersen, J. S., Ren, G.
, Geary, C. & Andersen, E. S. (2023).
Structure, folding and flexibility of co-transcriptional RNA origami.
Nature Nanotechnology,
18(7), 808-817.
https://doi.org/10.1038/s41565-023-01321-6
Martens, A. K., Erwig, M., Patzig, J., Fledrich, R.
, Füchtbauer, E. M. & Werner, H. B. (2023).
Targeted inactivation of the Septin2 and Septin9 genes in myelinating Schwann cells of mice.
Cytoskeleton,
80(7-8), 290-302.
https://doi.org/10.1002/cm.21736
Sønderby, T. V., Louros, N. N., Khodaparast, L., Khodaparast, L.
, Madsen, D. J., Olsen, W. P., Moonen, N.
, Nagaraj, M., Sereikaite, V.
, Strømgaard, K., Rousseau, F., Schymkowitz, J.
& Otzen, D. E. (2023).
Sequence-targeted Peptides Divert Functional Bacterial Amyloid Towards Destabilized Aggregates and Reduce Biofilm Formation.
Journal of Molecular Biology,
435(11), 168039. Artikel 168039.
https://doi.org/10.1016/j.jmb.2023.168039
Seeler, S., Andersen, M. S., Sztanka-Toth, T., Rybiczka-Tešulov, M., van den Munkhof, M. H.
, Chang, C. C., Maimaitili, M., Venø, M. T., Hansen, T. B., Pasterkamp, R. J., Rybak-Wolf, A.
, Denham, M., Rajewsky, N.
, Kristensen, L. S. & Kjems, J. (2023).
A Circular RNA Expressed from the FAT3 Locus Regulates Neural Development.
Molecular Neurobiology,
60(6), 3239–3260.
https://doi.org/10.1007/s12035-023-03253-7
Kuderna, L. F. K., Gao, H., Janiak, M. C., Kuhlwilm, M., Orkin, J. D.
, Bataillon, T., Manu, S., Valenzuela, A.
, Bergman, J., Rousselle, M., Silva, F. E., Agueda, L., Blanc, J., Gut, M., de Vries, D., Goodhead, I., Harris, R. A., Raveendran, M., Jensen, A. ... Bonet, T. M. (2023).
A global catalog of whole-genome diversity from 233 primate species.
Science,
380(6648), 906-913.
https://doi.org/10.1126/science.abn7829
Omelková, M., Fenger, C. D., Murray, M., Hammer, T. B., Pravata, V. M.
, Bartual, S. G., Czajewski, I., Bayat, A.
, Ferenbach, A. T., Stavridis, M. P.
& van Aalten, D. M. F. (2023).
An O-GlcNAc transferase pathogenic variant linked to intellectual disability affects pluripotent stem cell self-renewal.
DMM Disease Models and Mechanisms,
16(6), Artikel dmm049132.
https://doi.org/10.1242/dmm.049132
Catapano, C., Rahm, J. V.
, Omer, M., Teodori, L., Kjems, J., Dietz, M. S. & Heilemann, M. (2023).
Biased activation of the receptor tyrosine kinase HER2.
Cellular and Molecular Life Sciences,
80(6), Artikel 158.
https://doi.org/10.1007/s00018-023-04806-8
Martin, M., Nilsson, S. C., Eikrem, D., Fromell, K.
, Scavenius, C., Vogt, L. M., Bielecka, E., Potempa, J.
, Enghild, J. J., Nilsson, B., Ekdahl, K. N., Kapetanovic, M. C. & Blom, A. M. (2023).
Citrullination of C1-inhibitor as a mechanism of impaired complement regulation in rheumatoid arthritis.
Frontiers in Immunology,
14, Artikel 1203506.
https://doi.org/10.3389/fimmu.2023.1203506
Zhang, B. L., Chen, W., Wang, Z., Pang, W., Luo, M. T., Wang, S., Shao, Y., He, W. Q., Deng, Y., Zhou, L., Chen, J., Yang, M. M., Wu, Y., Wang, L., Fernández-Bellon, H., Molloy, S., Meunier, H., Wanert, F., Kuderna, L. ... Wu, D. D. (2023).
Comparative genomics reveals the hybrid origin of a macaque group.
Science Advances,
9(22), Artikel eadd3580.
https://doi.org/10.1126/sciadv.add3580
Stock, C., Heger, T., Hansen, S. B., Larsen, S. T., Habeck, M., Dieudonné, T. L. A., Driller, R. & Nissen, P. (2023).
Fast-forward on P-type ATPases: recent advances on structure and function.
Biochemical Society Transactions,
51(3), 1347-1360.
https://doi.org/10.1042/BST20221543
Sørensen, E. F., Harris, R. A., Zhang, L., Raveendran, M., Kuderna, L. F. K., Walker, J. A., Storer, J. M., Kuhlwilm, M., Fontsere, C., Seshadri, L., Bergey, C. M., Burrell, A. S.
, Bergman, J., Phillips-Conroy, J. E., Shiferaw, F., Chiou, K. L., Chuma, I. S., Keyyu, J. D., Fischer, J. ... Rogers, J. (2023).
Genome-wide coancestry reveals details of ancient and recent male-driven reticulation in baboons.
Science (New York, N.Y.),
380(6648), Artikel eabn8153.
https://doi.org/10.1126/science.abn8153
Cheng, Z., Ferris, C., Crowe, M. A.
, Ingvartsen, K. L., Grelet, C., Vanlierde, A.
, Foldager, L., Becker, F., Wathes, D. C. & GplusE Consortium (2023).
Hepatic global transcriptomic profiles of Holstein cows according to parity reveal age-related changes in early lactation.
International Journal of Molecular Sciences ,
24(12), Artikel 9906.
https://doi.org/10.3390/ijms24129906
Hao, D., Wang, X., Yang, Y., Chen, H.
, Thomsen, B. & Holm, L. E. (2023).
MicroRNA sequence variation can impact interactions with target mRNA in cattle.
Gene,
868, Artikel 147373.
https://doi.org/10.1016/j.gene.2023.147373
Rivas-González, I., Rousselle, M., Li, F., Zhou, L.
, Dutheil, J. Y., Munch, K., Shao, Y., Wu, D.
, Schierup, M. H. & Zhang, G. (2023).
Pervasive incomplete lineage sorting illuminates speciation and selection in primates.
Science,
380(6648), eabn4409. Artikel eabn4409.
https://doi.org/10.1126/science.abn4409
Shao, Y., Zhou, L., Li, F., Zhao, L., Zhang, B. L., Shao, F., Chen, J. W., Chen, C. Y., Bi, X., Zhuang, X. L., Zhu, H. L., Hu, J., Sun, Z., Li, X., Wang, D.
, Rivas-González, I., Wang, S., Wang, Y. M., Chen, W. ... Wu, D. D. (2023).
Phylogenomic analyses provide insights into primate evolution.
Science (New York, N.Y.),
380(6648), 913-924.
https://doi.org/10.1126/science.abn6919
Hayeck, T. J., Busby, G. B., Chun, S., Lewis, A. C. F., Roberts, M. C.
& Vilhjálmsson, B. J. (2023).
Polygenic Risk Scores: Genomes to Risk Prediction.
Clinical Chemistry,
69(6), 551–557.
https://doi.org/10.1093/clinchem/hvad049
Ding, Y., Hou, K., Xu, Z., Pimplaskar, A., Petter, E., Boulier, K.
, Privé, F., Vilhjálmsson, B. J., Olde Loohuis, L. M. & Pasaniuc, B. (2023).
Polygenic scoring accuracy varies across the genetic ancestry continuum.
Nature,
618, 774-781.
https://doi.org/10.1038/s41586-023-06079-4
Gielnik, M., Szymańska, A., Dong, X., Jarvet, J., Svedružić, Ž. M., Gräslund, A., Kozak, M. & Wärmländer, S. K. T. S. (2023).
Prion Protein Octarepeat Domain Forms Transient β-Sheet Structures upon Residue-Specific Binding to Cu(II) and Zn(II) Ions.
Biochemistry,
62(11), 1689-1705.
https://doi.org/10.1021/acs.biochem.3c00129
Bavnhøj, L., Driller, J. H., Zuzic, L., Stange, A. D., Schiøtt, B. & Pedersen, B. P. (2023).
Structure and sucrose binding mechanism of the plant SUC1 sucrose transporter.
Nature Plants,
9(6), 938-950.
https://doi.org/10.1038/s41477-023-01421-0
Romon-Ochoa, P., Smith, O., Lewis, A., Kupper, Q.
, Shamsi, W., Rigling, D., Pérez-Sierra, A. & Ward, L. (2023).
Temperature Effects on the Cryphonectria hypovirus 1 Accumulation and Recovery within Its Fungal Host, the Chestnut Blight Pathogen Cryphonectria parasitica.
Viruses,
15(6), Artikel 1260.
https://doi.org/10.3390/v15061260
Gao, H., Hamp, T., Ede, J., Schraiber, J. G., McRae, J., Singer-Berk, M., Yang, Y., Dietrich, A. S. D., Fiziev, P. P., Kuderna, L. F. K., Sundaram, L., Wu, Y., Adhikari, A., Field, Y., Chen, C., Batzoglou, S., Aguet, F., Lemire, G., Reimers, R. ... Farh, K. K. H. (2023).
The landscape of tolerated genetic variation in humans and primates.
Science (New York, N.Y.),
380(6648), Artikel abn8197.
https://doi.org/10.1126/science.abn8197
Olesen, H. G., Michailidou, I., Zelek, W. M., Vreijling, J., Ruizendaal, P., de Klein, F., Marquart, J. A., Kuipers, T. B., Mei, H., Zhang, Y., Ahasan, M., Johnson, K. K., Wang, Y., Morgan, B. P., van Dijk, M., Fluiter, K.
, Andersen, G. R. & Baas, F. (2023).
Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex.
Journal of Innate Immunity,
15(1), 16-36.
https://doi.org/10.1159/000524587
Zuzic, L., Marzinek, J., Anand, G., Warwicker, J. & Bond, P. J. (2023).
A pH-dependent cluster of charges in a conserved cryptic pocket on flaviviral envelopes.
eLife,
12, Artikel e82447.
https://doi.org/10.7554/eLife.82447
Fruergaard, M. U., Nielsen, C. J. F., Kjeldsen, C. R., Iversen, L., Andersen, J. L. & Nissen, P. (2023).
Activation and inhibition of the C-terminal kinase domain of p90 ribosomal S6 kinases.
Life Science Alliance,
6(5), Artikel e202201425.
https://doi.org/10.26508/lsa.202201425
Kelly, S., Hansen, S. B., Rübsam, H., Saake, P., Pedersen, E. B.
, Gysel, K., Madland, E., Wu, S., Wawra, S.
, Reid, D., Sullivan, J. T.
, Blahovska, Z., Vinther, M., Muszynski, A., Azadi, P., Thygesen, M. B., Aachmann, F. L., Ronson, C. W., Zuccaro, A.
... Stougaard, J. (2023).
A glycan receptor kinase facilitates intracellular accommodation of arbuscular mycorrhiza and symbiotic rhizobia in the legume Lotus japonicus.
PLoS Biology,
21(5), Artikel e3002127.
https://doi.org/10.1371/journal.pbio.3002127
Sun, C., Desch, K., Nassim-Assir, B., Giandomenico, S. L., Nemcova, P., Langer, J. D. & Schuman, E. M. (2023).
An abundance of free regulatory (19S) proteasome particles regulates neuronal synapses.
Science,
380(6647), Artikel 811.
https://doi.org/10.1126/SCIENCE.ADF2018
Keller, J. G.
, Petersen, K. V., Mizielinski, K.
, Thiesen, C., Bjergbæk, L., Reguera, R. M., Pérez-Pertejo, Y., Balaña-Fouce, R., Trejo, A., Masdeu, C., Alonso, C.
, Knudsen, B. R. & Tesauro, C. (2023).
Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds.
Pharmaceuticals,
16(5), Artikel 657.
https://doi.org/10.3390/ph16050657
Skovbjerg, C. K., Angra, D., Robertson-Shersby-Harvie, T., Kreplak, J., Keeble-Gagnère, G., Kaur, S., Ecke, W., Windhorst, A., Nielsen, L. K., Schiemann, A., Knudsen, J., Gutierrez, N., Tagkouli, V.
, Fechete, L. I., Janss, L., Stougaard, J., Warsame, A., Alves, S., Khazaei, H.
... Andersen, S. U. (2023).
Genetic analysis of global faba bean diversity, agronomic traits and selection signatures.
Theoretical and Applied Genetics,
136(5), Artikel 114.
https://doi.org/10.1007/s00122-023-04360-8
Chen, Y., Atashi, H., Grelet, C., Mota, R. R., Vanderick, S., Hu, H., GplusE Consortium & Gengler, N. (2023).
Genome-wide association study and functional annotation analyses for nitrogen efficiency index and its composition traits in dairy cattle.
Journal of Dairy Science,
106(5), 3397-3410.
https://doi.org/10.3168/jds.2022-22351
Wedge, E.
, Ahmadov, U., Hansen, T. B., Gao, Z., Tulstrup, M., Côme, C., Nonavinkere Srivatsan, S., Ahmed, T., Jespersen, J. S., Schlotmann, B. C., Schöllkopf, C., Raaschou-Jensen, K., Ødum, N.
, Kjems, J., Bak, R. O., Walter, M. J., Grønbæk, K.
& Kristensen, L. S. (2023).
Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms.
Leukemia,
37(5), 1113-1125.
https://doi.org/10.1038/s41375-023-01866-4
Lassen, J. K., Wang, T., Nielsen, K. L., Hasselstrøm, J. B., Johannsen, M. & Villesen, P. (2023).
Large-Scale metabolomics: Predicting biological age using 10,133 routine untargeted LC–MS measurements.
Aging Cell,
22(5), Artikel e13813.
https://doi.org/10.1111/acel.13813
Larsen, T. V., Daugaard, T. F., Gad, H. H., Hartmann, R. & Nielsen, A. L. (2023).
PD-L1 and PD-L2 immune checkpoint protein induction by type III interferon in non-small cell lung cancer cells.
Immunobiology,
228(3), Artikel 152389.
https://doi.org/10.1016/j.imbio.2023.152389
Sampedro Vallina, N., McRae, E. K. S., Hansen, B. K., Boussebayle, A. & Andersen, E. S. (2023).
RNA origami scaffolds facilitate cryo-EM characterization of a Broccoli-Pepper aptamer FRET pair.
Nucleic Acids Research,
51(9), 4613-4624.
https://doi.org/10.1093/nar/gkad224
Zhang, X., Galenkamp, N. S., Heide, N. J. V. D.
, Valero Moreno, J., Maglia, G.
& Kjems, J. (2023).
Specific Detection of Proteins by a Nanobody-Functionalized Nanopore Sensor.
ACS Nano,
17(10), 9167-9177.
https://doi.org/10.1021/acsnano.2c12733
Ng, K. W., Boumelha, J., Enfield, K. S. S., Almagro, J., Cha, H., Pich, O., Karasaki, T., Moore, D. A., Salgado, R., Sivakumar, M., Young, G., Molina-Arcas, M., de Carné Trécesson, S., Anastasiou, P., Fendler, A., Au, L., Shepherd, S. T. C., Martínez-Ruiz, C., Puttick, C. ... CAPTURE Consortium (2023).
Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
Nature,
616(7957), 563-573.
https://doi.org/10.1038/s41586-023-05771-9
Mohammad-Beigi, H., Wijaya, W., Madsen, M.
, Hayashi, Y., Li, R., Maria Rovers, T. A., Jæger, T. C., Buell, A. K., Hougaard, A. B., Kirkensgaard, J. J. K., Westh, P., Ipsen, R. & Svensson, B. (2023).
Association of caseins with β-lactoglobulin influenced by temperature and calcium ions: A multi-parameter analysis.
Food Hydrocolloids,
137, Artikel 108373.
https://doi.org/10.1016/j.foodhyd.2022.108373