Department of Molecular Biology and Genetics

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 Department of Molecular Biology and Genetics Research Research areas Neurobiology

Neurobiology

[Translate to English:] DANDRITE's logo

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE 

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.  

Groups at DANDRITE encompass ambitious research programs that include:

  • Molecular and cellular mechanisms of memory
  • Effort-based decision making
  • Neuronal development and stem cells
  • Motor control
  • Brain processing of vision
  • Neurological and neurodegenerative diseases
  • Psychiatric disorders
  • Neurotrophic receptors, sorting
  • Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

Group leaders

Professors

Associate Professors

Tenure Track Assistant Professor

Professor

Associate Professors

Tenure Track Assistant Professor

Peer-reviewed publications

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Vorup-Jensen, T. & Boesen, T. (2011). Protein ultrastructure and the nanoscience of complement activation. Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2011.05.023
Voldsgaard Clausen, M., Nissen, P. & Poulsen, H. (2016). The α4 isoform of the Na+ ,K+ -ATPase is tuned for changing extracellular environments. FEBS journal, 283(2), 282-293. https://doi.org/10.1111/febs.13567
Vöge, M., Pfaffhuber, A., Auken, E., Kirkegaard, C., Boesen, T., Hendricks, S. & Hunkeler, P. (2015). 5D inversion of sea ice thickness from helicopter EM data. In 1st European Airborne Electromagnetics Conference: Held at Near Surface Geoscience 2015 (pp. 41-45). European Association of Geoscientists and Engineers.
Villa, E., Sengupta, J., Trabuco, L. G., Lebarron, J., Baxter, W. T., Shaikh, T. R., Grasucci, R. A., Nissen, P., Ehrenberg, M., Schulten, K. & Joachim, F. (2009). Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis. Proceedings of the National Academy of Sciences (PNAS), 106(1), 1063-1068.
Verzelli, P., Nold, A., Sun, C., Heilemann, M., Schuman, E. M. & Tchumatchenko, T. (2022). Unbiased choice of global clustering parameters for single-molecule localization microscopy. Scientific Reports, 12(1), 22561. Article 22561. https://doi.org/10.1038/s41598-022-27074-1
Vandecaetsbeek, I., Christensen, S. B., Liu, H., Van Veldhoven, PP., Waelkens, E., Eggermont, J., Raeymaekers, L., Møller, J. V., Nissen, P., Wuytack, F. & Vangheluwe, P. (2011). Thapsigargin affinity purification of intracellular P(2A)-type Ca(2+) ATPases. BBA General Subjects, 1813(5), 1118-27.
Vandecaetsbeek, I., Christensen, S. B., Liu, H., Van Veldhoven, P. P., Waelkens, E., Eggermont, J., Raeymaekers, L., Møller, J. V., Nissen, P., Wuytack, F. & Vangheluwe, P. (2011). Thapsigargin affinity purification of intracellular P(2A)-type Ca(2+) ATPases. BBA General Subjects, 1813(5), 1118-27. https://doi.org/10.1016/j.bbamcr.2010.12.020
Valle, M., Zavialov, A., Li, W., Stagg, S. M., Sengupta, J., Nielsen, R. C., Nissen, P., Harvey, S. C., Ehrenberg, M. & Frank, J. (2003). Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy. Nat. Struct. Biol. ,10, 899-906.
Trampari, S., Neumann, C. M. T., Hjorth-Jensen, S. J., Shahsavar, A., Quistgaard, E. M. H. & Nissen, P. (2021). Insights into the mechanism of high lipid–detergent crystallization of membrane proteins. Journal of Applied Crystallography, 54(Part 6), 1775-1783. https://doi.org/10.1107/S1600576721010669
Toustrup-Jensen, M. S., Holm, R., Einholm, A. P., Schack, V. R., Morth, J. P., Nissen, P., Andersen, J. P. & Vilsen, B. (2009). The C Terminus of Na+,K+-ATPase Controls Na+ Affinity on Both Sides of the Membrane through Arg935. Journal of Biological Chemistry, 284(28), 18715-18725.
Timcenko, M., Lyons, J. A., Januliene, D., Ulstrup, J. J., Dieudonné, T., Montigny, C., Ash, M. R., Karlsen, J. L., Boesen, T., Kühlbrandt, W., Lenoir, G., Moeller, A. & Nissen, P. (2019). Structure and autoregulation of a P4-ATPase lipid flippase. Nature, 571(7765), 366-370. https://doi.org/10.1038/s41586-019-1344-7
Timcenko, M., Dieudonné, T., Montigny, C., Boesen, T., Lyons, J. A., Lenoir, G. & Nissen, P. (2021). Structural Basis of Substrate-Independent Phosphorylation in a P4-ATPase Lipid Flippase. Journal of Molecular Biology, 433(16), Article 167062. https://doi.org/10.1016/j.jmb.2021.167062

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Revised 13.11.2025
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Helene Eriksen