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Department of Molecular Biology and Genetics

Neurobiology

The Section for Neurobiology is part of the Danish Research Institute of Translational Neuroscience – DANDRITE

- the Danish node of the Nordic EMBL Partnership for Molecular Medicine, which performs basic and translational research in brain and the nervous system.

Groups at DANDRITE encompass ambitious research programs that include:

Molecular and cellular mechanisms of memory
Effort-based decision making
Neuronal development and stem cells
Motor control
Brain processing of vision
Neurological and neurodegenerative diseases
Psychiatric disorders
Neurotrophic receptors, sorting
Structural biology of membrane transporters and receptors

Read more about the research at DANDRITE.

Below you see the list of researchers at DANDRITE affiliated with the Department of Molecular Biology and Genetics.

List of staff and students in the research group

Group leaders

Professors

Associate Professors

Tenure Track Assistant Professor

Gilles Claude Vanwalleghem

Professor

Associate Professors

Tenure Track Assistant Professor

Peer-reviewed publications

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Nissen, P., Hansen, J., Ban, J., Moore, P. B. & Steitz, T. A. (2000). The structural basis for ribosome function in peptide bond synthesis. Science, 289, 920-930.

Nissen, P., Kjeldgaard, M. & Nyborg, J. (2000). Macromolecular mimicry. EMBO Journal, 19, 489-495.

Nissen, P., Thirup, S., Kjeldgaard, M. & Nyborg, J. (1999). The crystal structure of Cys-tRNA^Cys--EF-Tu--GDPNP reveals general and specific features in the ternary complex and in tRNA. Structure, 7, 143-156.

Nissen, P., Jensen, A.-M. L., Møller, J. V., Christensen, S. B., Søhoel, H., Olsen, C. E., Denmeade, S. R. & Isaacs, J. T. (2006). Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells. Bioorganic & Medicinal Chemistry, 14(8), 2810-2815.

Nissen, P., Kjeldgaard, M., Thirup, S., Clark, B. F. & Nyborg, J. (1996). The ternary complex of aminoacylated tRNA and EF-Tu-GTP. Recognition of a bond and a fold. Biochimie, 78(11-12), 921-33.

Nissen, P., Kjeldgaard, M., Thirup, S., Polekhina, G., Reshetnikova, L., Clark, B. F. & Nyborg, J. (1995). Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog. Science, 270(5241), 1464-72.

Nissen, P., Reshetnikova, L., Siboska, G., Polekhina, G., Thirup, S., Kjeldgaard, M., Clark, B. F. & Nyborg, J. (1994). Purification and crystallization of the ternary complex of elongation factor Tu:GTP and Phe-tRNA(Phe). FEBS Letters, 356(2-3), 165-8.

Nissen, P. (2012). A POTluck of peptide transporters. EMBO Journal, 31(16), 3382-3383. https://doi.org/10.1038/emboj.2012.206

Nissen, P. (2019). Thomas A. Steitz (1940-2018). Acta Crystallographica Section D: Structural Biology, 75, 354-356. https://doi.org/10.1107/S2059798319002390

Nissen, P. (2020). The a-minor motif. In Structural Insights into Gene Expression and Protein Synthesis (pp. 461-463). World Scientific. https://doi.org/10.1142/9789811215865_0055

Nissen, P., Jensen, A. M. L., Marchand, A., Olesen, C., Holm, P., Picard, M., Vilsen, B., Jaxel, C., Champeil, P., Andersen, J. P., LE MAIRE, M. & Møller, J. V. (2006). The structure and function of the sarcoplasmic reticulum Ca ²⁺-ATPase. Acta Biomedica de l'Ateneo Parmense, 77(SUPPL. 3), 25-26.

Nilsson, J., Sengupta, J., Frank, J. & Nissen, P. (2004). Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome. EMBO Reports, 5, 1137-1141.

Displaying results 97 to 108 out of 314

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Revised 13.11.2025

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Helene Eriksen