Nordeen, S. A.
, Andersen, K. R., Knockenhauer, K. E., Ingram, J. R., Ploegh, H. L. & Schwartz, T. U. (2020).
A nanobody suite for yeast scaffold nucleoporins provides details of the nuclear pore complex structure.
Nature Communications,
11(1), Artikel 6179.
https://doi.org/10.1038/s41467-020-19884-6
Hait, A. S., Olagnier, D., Sancho-Shimizu, V.
, Skipper, K. A., Helleberg, M.
, Larsen, S. M., Bodda, C., Moldovan, L. I., Ren, F., Brinck Andersen, N.-S., Thomsen, M. M., Freytag, M. R., Darmalinggam, S., Parkes, I.
, Kadekar, D. D., Rahbek, S. H., van der Horst, D., Kristensen, L. S., Eriksson, K.
... Mogensen, T. H. (2020).
Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans.
Science Immunology,
5(54), Artikel eabc2691.
https://doi.org/10.1126/sciimmunol.abc2691
Schytte, G. N., Christensen, B., Bregenov, I., Kjøge, K., Scavenius, C., Petersen, S. V., Enghild, J. J. & Sørensen, E. S. (2020).
FAM20C phosphorylation of the RGDSVVYGLR motif in osteopontin inhibits interaction with the αvβ3 integrin.
Journal of Cellular Biochemistry,
121(12), 4809-4818.
https://doi.org/10.1002/jcb.29708
Lee, Y. L., Takada, H., Moreira, G. C. M., Karim, L., GplusE Consortium, Bosse, M., Bouwman, A., Mullaart, E., Coppieters, W., Georges, M., Druet, T. & Charlier, C. (2020).
Fine resolution CNV catalogue from deeply sequenced cattle genomes. I
Book of Abstracts of the 71st Annual Meeting of the European Federation of Animal Science (Bind 26, s. 188). Wageningen Academic Publishers.
https://doi.org/10.3920/978-90-8686-900-8
Omer, M., Andersen, V. L., Nielsen, J. S., Wengel, J.
& Kjems, J. (2020).
Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds.
Molecular Therapy - Nucleic Acids,
22, 994-1003.
https://doi.org/10.1016/j.omtn.2020.10.013
Dalskov, L., Møhlenberg, M., Thyrsted, J., Blay-Cadanet, J., Poulsen, E. T., Folkersen, B. H., Skaarup, S. H., Olagnier, D., Reinert, L., Enghild, J. J., Hoffmann, H. J., Holm, C. K. & Hartmann, R. (2020).
SARS-CoV-2 evades immune detection in alveolar macrophages.
EMBO Reports,
21(12), Artikel e51252.
https://doi.org/10.15252/embr.202051252
Favre-Bulle, I. A., Taylor, M. A., Marquez-Legorreta, E.
, Vanwalleghem, G., Poulsen, R. E., Rubinsztein-Dunlop, H. & Scott, E. K. (2020).
Sound generation in zebrafish with Bio-Opto-Acoustics.
Nature Communications,
11(1), Artikel 6120.
https://doi.org/10.1038/s41467-020-19982-5
Kristensen, L. S., Ebbesen, K. K., Sokol, M., Jakobsen, T., Korsgaard, U., Eriksen, A. C.
, Hansen, T. B., Kjems, J. & Hager, H. (2020).
Spatial expression analyses of the putative oncogene ciRS-7 in cancer reshape the microRNA sponge theory.
Nature Communications,
11, Artikel 4551.
https://doi.org/10.1038/s41467-020-18355-2
Harwood, S. L., Nielsen, N. S., Pedersen, H., Kjøge, K., Nielsen, P. K.
, Andersen, G. R. & Enghild, J. J. (2020).
Substituting the Thiol Ester of Human A2M or C3 with a Disulfide Produces Native Proteins with Altered Proteolysis-Induced Conformational Changes.
Biochemistry,
59(51), 4799–4809.
https://doi.org/10.1021/acs.biochem.0c00803
Bailey, S., Sroga, G. E., Hoac, B., Katsamenis, O. L., Wang, Z., Bouropoulos, N., McKee, M. D.
, Sørensen, E. S., Thurner, P. J. & Vashishth, D. (2020).
The role of extracellular matrix phosphorylation on energy dissipation in bone.
eLife,
9, 1-19. Artikel e58184.
https://doi.org/10.7554/eLife.58184
Okholm, T. L. H., Sathe, S., Park, S. S.
, Kamstrup, A. B., Rasmussen, A. M., Shankar, A., Chua, Z. M.
, Fristrup, N., Nielsen, M. M., Vang, S., Dyrskjøt, L., Aigner, S.
, Damgaard, C. K., Yeo, G. W.
& Pedersen, J. S. (2020).
Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression.
Genome Medicine,
12(112), Artikel 112.
https://doi.org/10.1186/s13073-020-00812-8
Higashijima, Y., Nagai, N., Yamamoto, M.
, Kitazawa, T., Kawamura, Y. K., Taguchi, A., Nakada, N., Nangaku, M., Furukawa, T., Aburatani, H., Kurihara, H., Wada, Y. & Kanki, Y. (2020).
Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.
Communications Biology,
3(1), 725. Artikel 725.
https://doi.org/10.1038/s42003-020-01456-5
Martins, P. M., Navarro, S., Silva, A., Pinto, M. F., Sárkány, Z., Figueiredo, F., Pereira, P. J. B., Pinheiro, F., Bednarikova, Z., Burdukiewicz, M., Galzitskaya, O. V., Gazova, Z., Gomes, C. M., Pastore, A., Serpell, L. C., Skrabana, R., Smirnovas, V., Ziaunys, M.
, Otzen, D. E. ... Macedo-Ribeiro, S. (2020).
MIRRAGGE - Minimum Information Required for Reproducible AGGregation Experiments.
Frontiers in Molecular Neuroscience,
13, Artikel 582488.
https://doi.org/10.3389/fnmol.2020.582488
Wong, E. S., Zheng, D., Tan, S. Z., Bower, N. I., Garside, V.
, Vanwalleghem, G., Gaiti, F., Scott, E., Hogan, B. M., Kikuchi, K., McGlinn, E., Francois, M. & Degnan, B. M. (2020).
Deep conservation of the enhancer regulatory code in animals.
Science,
370(6517), Artikel eaax8137.
https://doi.org/10.1126/science.aax8137
Dai, L., Hallmark, L.
, Bofill De Ros, X., Crouch, H., Chen, S., Shi, T., Yang, A., Lian, C., Zhao, Y., Tran, B. & Gu, S. (2020).
Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells.
RNA Biology,
17(11), 1603-1612.
https://doi.org/10.1080/15476286.2020.1813439
Stoll, L., Rodríguez-Trejo, A., Guay, C., Brozzi, F., Bayazit, M. B., Gattesco, S., Menoud, V., Sobel, J., Marques, A. C.
, Venø, M. T., Esguerra, J. L. S., Barghouth, M., Suleiman, M., Marselli, L.
, Kjems, J., Eliasson, L., Renström, E., Bouzakri, K., Pinget, M. ... Regazzi, R. (2020).
A circular RNA generated from an intron of the insulin gene controls insulin secretion.
Nature Communications,
11, Artikel 5611.
https://doi.org/10.1038/s41467-020-19381-w
Zhang, B.
, Nandakumar, R., Reinert, L. S., Huang, J., Laustsen, A., Gao, Z., Sun, C.
, Jensen, S. B., Troldborg, A., Assil, S., Berthelsen, M. F., Scavenius, C., Zhang, Y., Windross, S. J., Olagnier, D., Prabakaran, T., Bodda, C.
, Narita, R., Cai, Y. ... Paludan, S. R. (2020).
Author Correction: STEEP mediates STING ER exit and activation of signaling (Nature Immunology, (2020), 21, 8, (868-879), 10.1038/s41590-020-0730-5).
Nature Immunology,
21(11), 1468-1469.
https://doi.org/10.1038/s41590-020-0803-5
Dalskov, L., Narita, R., Andersen, L. L., Jensen, N., Assil, S., Kristensen, K. H., Mikkelsen, J. G., Fujita, T.
, Mogensen, T. H., Paludan, S. R. & Hartmann, R. (2020).
Characterization of distinct molecular interactions responsible for IRF3 and IRF7 phosphorylation and subsequent dimerization.
Nucleic Acids Research,
48(20), 11421-11433.
https://doi.org/10.1093/nar/gkaa873
Hollensen, A. K., Thomsen, H. S., Lloret-Llinares, M., Kamstrup, A. B., Jensen, J. M., Luckmann, M., Birkmose, N., Palmfeldt, J., Jensen, T. H., Hansen, T. B. & Damgaard, C. K. (2020).
circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation.
eLife,
9, 1-29. Artikel e58478.
https://doi.org/10.7554/eLife.58478
Conrad, T., Ntini, E., Lang, B., Cozzuto, L., Andersen, J. B., Marquardt, J. U., Ponomarenko, J., Tartaglia, G. G.
& Ørom, U. A. V. (2020).
Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing.
RNA,
26(11), 1726-1730.
https://doi.org/10.1261/rna.076240.120
Aminzadeh, A., Tiwari, M. K., Mamah Mustapha, S. S., Navarrete, S. J., Henriksen, A. B.
, Møller, I. M., Krogfelt, K. A., Bjerrum, M. J. & Jørgensen, R. (2020).
Detoxification of toxin A and toxin B by copper ion-catalyzed oxidation in production of a toxoid-based vaccine against Clostridioides difficile.
Free Radical Biology and Medicine,
160, 433-446.
https://doi.org/10.1016/j.freeradbiomed.2020.08.021
Peltonen, J., Tuomainen, K., Sallinen, T.
, Faress, I., Suleymanova, I., Al-Samadi, A., Salo, T. & Åström, P. (2020).
Effect of sex steroid hormones on tongue cancer cells in vitro.
Anticancer Research,
40(11), 6029-6037.
https://doi.org/10.21873/anticanres.14624
Arora, D.
, Abel, N. B., Liu, C., van Damme, P., Yperman, K., Eeckhout, D., Vu, L. D.
, Wang, J., Tornkvist, A., Impens, F., Korbei, B., van Leene, J., Goossens, A., de Jaeger, G., Ott, T., Moschou, P. N. & van Damme, D. (2020).
Establishment of proximity-dependent biotinylation approaches in different plant model systems.
Plant Cell,
32(11), 3388-3407.
https://doi.org/10.1105/TPC.20.00235
Küssau, T., Van Wyk, N., Johansen, M. D.
, Alsarraf, H. M. A. B., Neyret, A., Hamela, C., Sørensen, K. K., Thygesen, M. B., Beauvineau, C., Kremer, L. & Blaise, M. (2020).
Functional Characterization of the N-Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus.
Cells,
9(11), 1-25. Artikel 2410.
https://doi.org/10.3390/cells9112410
Hampton, H. G., Smith, L. M.
, Ferguson, S., Meaden, S., Jackson, S. A. & Fineran, P. C. (2020).
Functional genomics reveals the toxin-antitoxin repertoire and AbiE activity in Serratia.
Microbial Genomics,
6(11), 1-15. Artikel 000458.
https://doi.org/10.1099/mgen.0.000458
Adams, M. J., Howard, D. M., Luciano, M., Clarke, T.-K., Davies, G., Hill, W. D., Smith, D., Deary, I. J., Porteous, D. J., McIntosh, A. M., 23andMe Research Team & Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium (2020).
Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition.
Psychological Medicine,
50(15), 2526–2535.
https://doi.org/10.1017/S0033291719002629
Holt-Danborg, L., Skovbjerg, S., Goderum, K. W., Nonboe, A. W., Stankevic, E.
, Frost, Á. K., Vitved, L.
, Jensen, J. K. & Vogel, L. K. (2020).
Insights into the regulation of the matriptase-prostasin proteolytic system.
The Biochemical journal,
477(22), 4349-4365.
https://doi.org/10.1042/BCJ20200630
Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N.
, Kjems, J. ... LifeTime Community Working Groups (2020).
LifeTime and improving European healthcare through cell-based interceptive medicine.
Nature,
587, 377-386.
https://doi.org/10.1038/s41586-020-2715-9
Moesgaard, L., Petersen, D., Szomek, M., Reinholdt, P.
, Winkler, M., Frain, K. M., Müller, P.
, Pedersen, B. P., Kongsted, J. & Wüstner, D. (2020).
Mechanistic Insight into Lipid Binding to Yeast Niemann Pick Type C2 Protein.
Biochemistry,
59(45), 4407–4420.
https://doi.org/10.1021/acs.biochem.0c00574
Lukassen, M. V., Poulsen, E. T., Donaghy, J.
, Mogensen, E. H., Christie, K. A., Roshanravan, H., DeDioniso, L., Nesbit, M. A., Moore, T.
& Enghild, J. J. (2020).
Protein Analysis of the TGFBIR124H Mouse Model Gives Insight into Phenotype Development of Granular Corneal Dystrophy.
Proteomics - Clinical Applications,
14(6), Artikel 1900072.
https://doi.org/10.1002/prca.201900072
Gokuldass, A., Draghi, A., Papp, K., Borch, T., Nielsen, M., Wulff Westergaard, M. C., Andersen, R., Schina, A., Bol, K. F., Chamberlain, C. A., Presti, M., Met, Ö., Harbst, K., Lauss, M.
, Soraggi, S., Csabai, I., Szallasi, Z., Jönsson, G., Svane, I. M. & Donia, M. (2020).
Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8+ T Cells in Non-Melanoma Cancers Compared to Melanoma.
Cancers,
12(11), 1-15. Artikel 3344.
https://doi.org/10.3390/cancers12113344
Bodó, K.
, Hayashi, Y., Gerencsér, G., László, Z., Kéri, A., Galbács, G., Telek, E., Mészáros, M., Deli, M. A., Kokhanyuk, B., Németh, P. & Engelmann, P. (2020).
Species-specific sensitivity of Eisenia earthworms towards noble metal nanoparticles: a multiparametric in vitro study.
Environmental Science: Nano,
7(11), 3509-3525.
https://doi.org/10.1039/c9en01405e
Manav, M. C., Van, L. B., Lin, J., Fuglsang, A., Peng, X.
& Brodersen, D. E. (2020).
Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein.
Nature Communications,
11(1), Artikel 5993.
https://doi.org/10.1038/s41467-020-19847-x
Stevenson, A. J.
, Vanwalleghem, G., Stewart, T. A., Condon, N. D., Lloyd-Lewis, B., Marino, N., Putney, J. W., Scott, E. K., Ewing, A. D.
& Davis, F. M. (2020).
Multiscale imaging of basal cell dynamics in the functionally mature mammary gland.
Proceedings of the National Academy of Sciences,
117(43), 26822-26832.
https://doi.org/10.1073/pnas.2016905117
Pedersen, H., Jensen, R. K., Jensen, J. M. B., Fox, R.
, Pedersen, D. V., Olesen, H. G., Hansen, A. G., Christiansen, D.
, Mazarakis, S. M. M., Lojek, N.
, Hansen, P., Gadeberg, T. A. F., Zarantonello, A., Laursen, N. S., Mollnes, T. E., Johnson, M. B., Stevens, B.
, Thiel, S. & Andersen, G. R. (2020).
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
Journal of Immunology,
205(8), 2287-2300.
https://doi.org/10.4049/jimmunol.2000752
Dou, Y., Kalmykova, S., Pashkova, M., Oghbaie, M., Jiang, H., Molloy, K. R., Chait, B. T., Rout, M. P., Fenyö, D.
, Jensen, T. H., Altukhov, I. & LaCava, J. (2020).
Affinity proteomic dissection of the human nuclear cap-binding complex interactome.
Nucleic Acids Research,
48(18), 10456-10469.
https://doi.org/10.1093/nar/gkaa743
Felgenhauer, U., Schoen, A.
, Gad, H. H., Hartmann, R., Schaubmar, A. R., Failing, K., Drosten, C. & Weber, F. (2020).
Inhibition of SARS-CoV-2 by type I and type III interferons.
The Journal of Biological Chemistry,
295(41), 13958-13964.
https://doi.org/10.1074/jbc.AC120.013788
Eskandari, H., Ghanadian, M., Noleto-Dias, C., Lomax, C., Tawfike, A.
, Christiansen, G., Sutherland, D. S., Ward, J. L.
, Mohammad-Beigi, H. & Otzen, D. E. (2020).
Inhibitors of α-Synuclein fibrillation and oligomer toxicity in Rosa damascena: the all-pervading powers of flavonoids and phenolic glycosides.
ACS Chemical Neuroscience,
11(19), 3161–3173.
https://doi.org/10.1021/acschemneuro.0c00528
Gonçalves, N. P., Yan, Y., Ulrichsen, M., Venø, M. T., Poulsen, E. T., Enghild, J. J., Kjems, J. & Vægter, C. B. (2020).
Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin.
Biomedicines,
8(11), 1-24. Artikel 450.
https://doi.org/10.3390/biomedicines8110450
Bodó, K., Baranzini, N., Girardello, R., Kokhanyuk, B., Németh, P.
, Hayashi, Y., Grimaldi, A. & Engelmann, P. (2020).
Nanomaterials and Annelid Immunity: A Comparative Survey to Reveal the Common Stress and Defense Responses of Two Sentinel Species to Nanomaterials in the Environment.
Biology,
9(10), 1-22. Artikel 307.
https://doi.org/10.3390/biology9100307
Dou, Y., Barbosa, I., Jiang, H.
, Iasillo, C., Molloy, K. R., Schulze, W. M., Cusack, S.
, Schmid, M., Le Hir, H., LaCava, J.
& Jensen, T. H. (2020).
NCBP3 positively impacts mRNA biogenesis.
Nucleic Acids Research,
48(18), 10413-10427.
https://doi.org/10.1093/nar/gkaa744
Poulsen, E. T., Lumi, X.
, Hansen, A. K., Enghild, J. J. & Petrovski, G. (2020).
Protein Composition of the Subretinal Fluid Suggests Selective Diffusion of Vitreous Proteins in Retinal Detachment.
Translational vision science & technology,
9(11), 16. Artikel 16.
https://doi.org/10.1167/tvst.9.11.16
Chen, M., Maimaitili, M., Habekost, M., Gill, K. P., Mermet-Joret, N., Nabavi, S., Febbraro, F. & Denham, M. (2020).
Rapid generation of regionally specified CNS neurons by sequential patterning and conversion of human induced pluripotent stem cells.
Stem Cell Research,
48, Artikel 101945.
https://doi.org/10.1016/j.scr.2020.101945
Jørgensen, S. E., Christiansen, M., Høst, C., Glerup, M., Mahler, B., Lausten, M. M., Gad, H. H., Hartmann, R., Herlin, T. & Mogensen, T. H. (2020).
Systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome due to a CASP1 variant causing inflammasome hyperactivation.
Rheumatology (Oxford, England),
59(10), 3099-3105.
https://doi.org/10.1093/rheumatology/keaa242