Østergaard, S. D., Trabjerg, B. B., Als, T. D., Albiñana, C., Privé, F., Vilhjálmsson, B. J., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Nordentoft, M., Werge, T.
, Demontis, D., Mortensen, P. B., Børglum, A. D., Mors, O. & Agerbo, E. (2020).
Polygenic risk score, psychosocial environment and the risk of attention-deficit/hyperactivity disorder.
Translational Psychiatry,
10(1), Artikel 335.
https://doi.org/10.1038/s41398-020-01019-6
Godskesen, L. E.
, Lassen, T. R., Jespersen, N. R., Siersbæk, M.
, Yan, Y., Nielsen, M. M., Tjønnfjord, S. K., Grøntved, L., Madsen, G.
, Kjems, J., Bøtker, H. E., Schmidt, M. R., Krag, A. & Kjeldsen, J. (2020).
Remote ischemic conditioning in active ulcerative colitis: An explorative randomized clinical trial.
Scientific Reports,
10(1), Artikel 9537.
https://doi.org/10.1038/s41598-020-65692-9
Thoma, J., Abuillan, W., Furikado, I., Habe, T., Yamamoto, A.
, Gierlich, S., Kaufmann, S., Brandenburg, K., Gutsmann, T., Konovalov, O., Inoue, S. & Tanaka, M. (2020).
Specific localisation of ions in bacterial membranes unravels physical mechanism of effective bacteria killing by sanitiser.
Scientific Reports,
10(1), 12302. Artikel 12302.
https://doi.org/10.1038/s41598-020-69064-1
Andrzejczak, O. A., Sørensen, C. K., Wang, W.-Q., Kovalchuk, S., Hagensen, C. E., Jensen, O. N.
, Carciofi, M., Hovmøller, M. S., Rogowska-Wrzesinska, A.
, Møller, I. M. & Hebelstrup, K. (2020).
The effect of phytoglobin overexpresseion on the plant proteome during nonhost response of barley (Hordeum vulgare) to wheat powdery mildew (Blumeria graminis f. sp. tritici).
Scientific Reports,
10(1), Artikel 9192.
https://doi.org/10.1038/s41598-020-65907-z
Gotfryd, K.
, Boesen, T., Mortensen, J. S., Khelashvili, G., Quick, M., Terry, D. S., Missel, J. W., LeVine, M. V., Gourdon, P., Blanchard, S. C., Javitch, J. A., Weinstein, H., Loland, C. J.
, Nissen, P. & Gether, U. (2020).
X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release.
Nature Communications,
11(1), Artikel 1005.
https://doi.org/10.1038/s41467-020-14735-w
Cai, H.
, Holleufer, A., Simonsen, B., Schneider, J., Lemoine, A.
, Gad, H. H., Huang, J., Huang, J., Chen, D., Peng, T., Marques, J. T.
, Hartmann, R., Martins, N. E. & Imler, J. L. (2020).
2'3'-cGAMP triggers a STING- and NF-κB-dependent broad antiviral response in Drosophila.
Science Signaling,
13(660), Artikel eabc4537.
https://doi.org/10.1126/scisignal.abc4537
Das Mahapatra, K., Pasquali, L., Søndergaard, J. N., Lapins, J., Nemeth, I. B., Baltás, E., Kemény, L., Homey, B.
, Moldovan, L. I., Kjems, J., Kutter, C., Sonkoly, E.
, Kristensen, L. S. & Pivarcsi, A. (2020).
A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma.
Scientific Reports,
10, Artikel 3637.
https://doi.org/10.1038/s41598-020-59660-6
Hajipour, M. J.
, Mohammad-Beigi, H., Nabipour, I., Mahmoudi, N., Azhdarzadeh, M., Derakhshankhah, H., El Dawud, D., Mohammadinejad, R.
& Otzen, D. (2020).
Amyloid fibril inhibition, acceleration, or fragmentation: Are nano-based approaches advance in the right direction? Nano Today,
35(December), Artikel 100983.
https://doi.org/10.1016/j.nantod.2020.100983
Nordeen, S. A.
, Andersen, K. R., Knockenhauer, K. E., Ingram, J. R., Ploegh, H. L. & Schwartz, T. U. (2020).
A nanobody suite for yeast scaffold nucleoporins provides details of the nuclear pore complex structure.
Nature Communications,
11(1), Artikel 6179.
https://doi.org/10.1038/s41467-020-19884-6
Pedersen, H. S., Mazzoni, G., Pihl, M.
, Kadarmideen, H., Hyttel, P.
& Callesen, H. (2020).
Bovine in-vitro produced embryos: development of embryo proper and associated membranes from day 26 to 47 of gestation.
Reproductive Biology,
20(4), 595-599.
https://doi.org/10.1016/j.repbio.2020.10.001
Schytte, G. N., Christensen, B., Bregenov, I., Kjøge, K., Scavenius, C., Petersen, S. V., Enghild, J. J. & Sørensen, E. S. (2020).
FAM20C phosphorylation of the RGDSVVYGLR motif in osteopontin inhibits interaction with the αvβ3 integrin.
Journal of Cellular Biochemistry,
121(12), 4809-4818.
https://doi.org/10.1002/jcb.29708
Lee, Y. L., Takada, H., Moreira, G. C. M., Karim, L., GplusE Consortium, Bosse, M., Bouwman, A., Mullaart, E., Coppieters, W., Georges, M., Druet, T. & Charlier, C. (2020).
Fine resolution CNV catalogue from deeply sequenced cattle genomes. I
Book of Abstracts of the 71st Annual Meeting of the European Federation of Animal Science (Bind 26, s. 188). Wageningen Academic Publishers.
https://doi.org/10.3920/978-90-8686-900-8
Omer, M., Andersen, V. L., Nielsen, J. S., Wengel, J.
& Kjems, J. (2020).
Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds.
Molecular Therapy - Nucleic Acids,
22, 994-1003.
https://doi.org/10.1016/j.omtn.2020.10.013
Higashijima, Y., Nagai, N., Yamamoto, M.
, Kitazawa, T., Kawamura, Y. K., Taguchi, A., Nakada, N., Nangaku, M., Furukawa, T., Aburatani, H., Kurihara, H., Wada, Y. & Kanki, Y. (2020).
Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.
Communications Biology,
3(1), 725. Artikel 725.
https://doi.org/10.1038/s42003-020-01456-5
Dalskov, L., Møhlenberg, M., Thyrsted, J., Blay-Cadanet, J., Poulsen, E. T., Folkersen, B. H., Skaarup, S. H., Olagnier, D., Reinert, L., Enghild, J. J., Hoffmann, H. J., Holm, C. K. & Hartmann, R. (2020).
SARS-CoV-2 evades immune detection in alveolar macrophages.
EMBO Reports,
21(12), Artikel e51252.
https://doi.org/10.15252/embr.202051252
Favre-Bulle, I. A., Taylor, M. A., Marquez-Legorreta, E.
, Vanwalleghem, G., Poulsen, R. E., Rubinsztein-Dunlop, H. & Scott, E. K. (2020).
Sound generation in zebrafish with Bio-Opto-Acoustics.
Nature Communications,
11(1), Artikel 6120.
https://doi.org/10.1038/s41467-020-19982-5
Kristensen, L. S., Ebbesen, K. K., Sokol, M., Jakobsen, T., Korsgaard, U., Eriksen, A. C.
, Hansen, T. B., Kjems, J. & Hager, H. (2020).
Spatial expression analyses of the putative oncogene ciRS-7 in cancer reshape the microRNA sponge theory.
Nature Communications,
11, Artikel 4551.
https://doi.org/10.1038/s41467-020-18355-2
Manav, M. C., Van, L. B., Lin, J., Fuglsang, A., Peng, X.
& Brodersen, D. E. (2020).
Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein.
Nature Communications,
11(1), Artikel 5993.
https://doi.org/10.1038/s41467-020-19847-x
Bailey, S., Sroga, G. E., Hoac, B., Katsamenis, O. L., Wang, Z., Bouropoulos, N., McKee, M. D.
, Sørensen, E. S., Thurner, P. J. & Vashishth, D. (2020).
The role of extracellular matrix phosphorylation on energy dissipation in bone.
eLife,
9, 1-19. Artikel e58184.
https://doi.org/10.7554/eLife.58184
Okholm, T. L. H., Sathe, S., Park, S. S.
, Kamstrup, A. B., Rasmussen, A. M., Shankar, A., Chua, Z. M.
, Fristrup, N., Nielsen, M. M., Vang, S., Dyrskjøt, L., Aigner, S.
, Damgaard, C. K., Yeo, G. W.
& Pedersen, J. S. (2020).
Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression.
Genome Medicine,
12(112), Artikel 112.
https://doi.org/10.1186/s13073-020-00812-8
Árnadóttir, S. S., Mattesen, T. B., Vang, S., Madsen, M. R., Madsen, A. H., Birkbak, N. J., Bramsen, J. B. & Andersen, C. L. (2020).
Transcriptomic and proteomic intra-tumor heterogeneity of colorectal cancer varies depending on tumor location within the colorectum.
PLoS One,
15(12), Artikel e0241148.
https://doi.org/10.1371/journal.pone.0241148
Martins, P. M., Navarro, S., Silva, A., Pinto, M. F., Sárkány, Z., Figueiredo, F., Pereira, P. J. B., Pinheiro, F., Bednarikova, Z., Burdukiewicz, M., Galzitskaya, O. V., Gazova, Z., Gomes, C. M., Pastore, A., Serpell, L. C., Skrabana, R., Smirnovas, V., Ziaunys, M.
, Otzen, D. E. ... Macedo-Ribeiro, S. (2020).
MIRRAGGE - Minimum Information Required for Reproducible AGGregation Experiments.
Frontiers in Molecular Neuroscience,
13, Artikel 582488.
https://doi.org/10.3389/fnmol.2020.582488
Holt-Danborg, L., Skovbjerg, S., Goderum, K. W., Nonboe, A. W., Stankevic, E.
, Frost, Á. K., Vitved, L.
, Jensen, J. K. & Vogel, L. K. (2020).
Insights into the regulation of the matriptase-prostasin proteolytic system.
Biochemical Journal,
477(22), 4349-4365.
https://doi.org/10.1042/BCJ20200630
Moesgaard, L., Petersen, D., Szomek, M., Reinholdt, P.
, Winkler, M., Frain, K. M., Müller, P.
, Pedersen, B. P., Kongsted, J. & Wüstner, D. (2020).
Mechanistic Insight into Lipid Binding to Yeast Niemann Pick Type C2 Protein.
Biochemistry,
59(45), 4407–4420.
https://doi.org/10.1021/acs.biochem.0c00574
Wong, E. S., Zheng, D., Tan, S. Z., Bower, N. I., Garside, V.
, Vanwalleghem, G., Gaiti, F., Scott, E., Hogan, B. M., Kikuchi, K., McGlinn, E., Francois, M. & Degnan, B. M. (2020).
Deep conservation of the enhancer regulatory code in animals.
Science,
370(6517), Artikel eaax8137.
https://doi.org/10.1126/science.aax8137
Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M.
, McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, M.
, Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, T.
, Svenning, J.-C. & Horsdal, H. T. (2020).
Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia.
Schizophrenia Bulletin,
46(6), 1629-1637.
https://doi.org/10.1093/schbul/sbaa058
Dai, L., Hallmark, L.
, Bofill De Ros, X., Crouch, H., Chen, S., Shi, T., Yang, A., Lian, C., Zhao, Y., Tran, B. & Gu, S. (2020).
Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells.
RNA Biology,
17(11), 1603-1612.
https://doi.org/10.1080/15476286.2020.1813439
Stoll, L., Rodríguez-Trejo, A., Guay, C., Brozzi, F., Bayazit, M. B., Gattesco, S., Menoud, V., Sobel, J., Marques, A. C.
, Venø, M. T., Esguerra, J. L. S., Barghouth, M., Suleiman, M., Marselli, L.
, Kjems, J., Eliasson, L., Renström, E., Bouzakri, K., Pinget, M. ... Regazzi, R. (2020).
A circular RNA generated from an intron of the insulin gene controls insulin secretion.
Nature Communications,
11, Artikel 5611.
https://doi.org/10.1038/s41467-020-19381-w
Zhang, B.
, Nandakumar, R., Reinert, L. S., Huang, J., Laustsen, A., Gao, Z., Sun, C.
, Jensen, S. B., Troldborg, A., Assil, S., Berthelsen, M. F., Scavenius, C., Zhang, Y., Windross, S. J., Olagnier, D., Prabakaran, T., Bodda, C.
, Narita, R., Cai, Y. ... Paludan, S. R. (2020).
Author Correction: STEEP mediates STING ER exit and activation of signaling (Nature Immunology, (2020), 21, 8, (868-879), 10.1038/s41590-020-0730-5).
Nature Immunology,
21(11), 1468-1469.
https://doi.org/10.1038/s41590-020-0803-5
Dalskov, L., Narita, R., Andersen, L. L., Jensen, N., Assil, S., Kristensen, K. H., Mikkelsen, J. G., Fujita, T.
, Mogensen, T. H., Paludan, S. R. & Hartmann, R. (2020).
Characterization of distinct molecular interactions responsible for IRF3 and IRF7 phosphorylation and subsequent dimerization.
Nucleic Acids Research,
48(20), 11421-11433.
https://doi.org/10.1093/nar/gkaa873
Conrad, T., Ntini, E., Lang, B., Cozzuto, L., Andersen, J. B., Marquardt, J. U., Ponomarenko, J., Tartaglia, G. G.
& Ørom, U. A. V. (2020).
Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing.
RNA,
26(11), 1726-1730.
https://doi.org/10.1261/rna.076240.120
Aminzadeh, A., Tiwari, M. K., Mamah Mustapha, S. S., Navarrete, S. J., Henriksen, A. B.
, Møller, I. M., Krogfelt, K. A., Bjerrum, M. J. & Jørgensen, R. (2020).
Detoxification of toxin A and toxin B by copper ion-catalyzed oxidation in production of a toxoid-based vaccine against Clostridioides difficile.
Free Radical Biology and Medicine,
160, 433-446.
https://doi.org/10.1016/j.freeradbiomed.2020.08.021
Peltonen, J., Tuomainen, K., Sallinen, T.
, Faress, I., Suleymanova, I., Al-Samadi, A., Salo, T. & Åström, P. (2020).
Effect of sex steroid hormones on tongue cancer cells in vitro.
Anticancer Research,
40(11), 6029-6037.
https://doi.org/10.21873/anticanres.14624
Arora, D.
, Abel, N. B., Liu, C., van Damme, P., Yperman, K., Eeckhout, D., Vu, L. D.
, Wang, J., Tornkvist, A., Impens, F., Korbei, B., van Leene, J., Goossens, A., de Jaeger, G., Ott, T., Moschou, P. N. & van Damme, D. (2020).
Establishment of proximity-dependent biotinylation approaches in different plant model systems.
Plant Cell,
32(11), 3388-3407.
https://doi.org/10.1105/TPC.20.00235
Adams, M. J., Howard, D. M., Luciano, M., Clarke, T.-K., Davies, G., Hill, W. D., Smith, D., Deary, I. J., Porteous, D. J., McIntosh, A. M., 23andMe Research Team & Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium (2020).
Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition.
Psychological Medicine,
50(15), 2526–2535.
https://doi.org/10.1017/S0033291719002629
Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N.
, Kjems, J. ... LifeTime Community Working Groups (2020).
LifeTime and improving European healthcare through cell-based interceptive medicine.
Nature,
587, 377-386.
https://doi.org/10.1038/s41586-020-2715-9
Gonçalves, N. P., Yan, Y., Ulrichsen, M., Venø, M. T., Poulsen, E. T., Enghild, J. J., Kjems, J. & Vægter, C. B. (2020).
Modulation of Small RNA Signatures in Schwann-Cell-Derived Extracellular Vesicles by the p75 Neurotrophin Receptor and Sortilin.
Biomedicines,
8(11), 1-24. Artikel 450.
https://doi.org/10.3390/biomedicines8110450
Watkins, T. B. K., Lim, E. L., Petkovic, M., Elizalde, S.
, Birkbak, N. J., Wilson, G. A., Moore, D. A., Grönroos, E., Rowan, A., Dewhurst, S. M., Demeulemeester, J., Dentro, S. C., Horswell, S., Au, L., Haase, K., Escudero, M., Rosenthal, R., Bakir, M. A., Xu, H. ... Swanton, C. (2020).
Pervasive chromosomal instability and karyotype order in tumour evolution.
Nature,
587, 126-132.
https://doi.org/10.1038/s41586-020-2698-6
Lukassen, M. V., Poulsen, E. T., Donaghy, J.
, Mogensen, E. H., Christie, K. A., Roshanravan, H., DeDioniso, L., Nesbit, M. A., Moore, T.
& Enghild, J. J. (2020).
Protein Analysis of the TGFBIR124H Mouse Model Gives Insight into Phenotype Development of Granular Corneal Dystrophy.
Proteomics - Clinical Applications,
14(6), Artikel 1900072.
https://doi.org/10.1002/prca.201900072
Gokuldass, A., Draghi, A., Papp, K., Borch, T., Nielsen, M., Wulff Westergaard, M. C., Andersen, R., Schina, A., Bol, K. F., Chamberlain, C. A., Presti, M., Met, Ö., Harbst, K., Lauss, M.
, Soraggi, S., Csabai, I., Szallasi, Z., Jönsson, G., Svane, I. M. & Donia, M. (2020).
Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8+ T Cells in Non-Melanoma Cancers Compared to Melanoma.
Cancers,
12(11), 1-15. Artikel 3344.
https://doi.org/10.3390/cancers12113344
Bodó, K.
, Hayashi, Y., Gerencsér, G., László, Z., Kéri, A., Galbács, G., Telek, E., Mészáros, M., Deli, M. A., Kokhanyuk, B., Németh, P. & Engelmann, P. (2020).
Species-specific sensitivity of Eisenia earthworms towards noble metal nanoparticles: a multiparametric in vitro study.
Environmental Science: Nano,
7(11), 3509-3525.
https://doi.org/10.1039/c9en01405e
Stevenson, A. J.
, Vanwalleghem, G., Stewart, T. A., Condon, N. D., Lloyd-Lewis, B., Marino, N., Putney, J. W., Scott, E. K., Ewing, A. D.
& Davis, F. M. (2020).
Multiscale imaging of basal cell dynamics in the functionally mature mammary gland.
Proceedings of the National Academy of Sciences (PNAS),
117(43), 26822-26832.
https://doi.org/10.1073/pnas.2016905117
Peña-Díaz, S., Pujols, J.
, Pinheiro, F., Santos, J., Pallarés, I., Navarro, S., Conde-Gimenez, M., García, J., Salvatella, X., Dalfó, E., Sancho, J. & Ventura, S. (2020).
Inhibition of α-Synuclein Aggregation and Mature Fibril Disassembling With a Minimalistic Compound, ZPDm.
Frontiers in Bioengineering and Biotechnology,
8, Artikel 588947.
https://doi.org/10.3389/fbioe.2020.588947
Pedersen, H., Jensen, R. K., Jensen, J. M. B., Fox, R.
, Pedersen, D. V., Olesen, H. G., Hansen, A. G., Christiansen, D.
, Mazarakis, S. M. M., Lojek, N.
, Hansen, P., Gadeberg, T. A. F., Zarantonello, A., Laursen, N. S., Mollnes, T. E., Johnson, M. B., Stevens, B.
, Thiel, S. & Andersen, G. R. (2020).
A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
Journal of Immunology,
205(8), 2287-2300.
https://doi.org/10.4049/jimmunol.2000752
Felgenhauer, U., Schoen, A.
, Gad, H. H., Hartmann, R., Schaubmar, A. R., Failing, K., Drosten, C. & Weber, F. (2020).
Inhibition of SARS-CoV-2 by type I and type III interferons.
The Journal of Biological Chemistry,
295(41), 13958-13964.
https://doi.org/10.1074/jbc.AC120.013788