Yu, Z., Centola, M.
, Valero, J., Matthies, M., Šulc, P. & Famulok, M. (2021).
A Self-Regulating DNA Rotaxane Linear Actuator Driven by Chemical Energy.
Journal of the American Chemical Society,
143(33), 13292-13298.
https://doi.org/10.1021/jacs.1c06226Moldovan, L. I., Tsoi, L. C., Ranjitha, U., Hager, H., Weidinger, S., Gudjonsson, J. E.
, Kjems, J. & Kristensen, L. S. (2021).
Characterization of Circular RNA Transcriptomes in Psoriasis and Atopic Dermatitis Reveals Disease-specific Expression Profiles.
Experimental Dermatology,
30(8), 1187-1196.
https://doi.org/10.1111/exd.14227
Mendoza-Suárez, M., Andersen, S. U., Poole, P. S. & Sánchez-Cañizares, C. (2021).
Competition, Nodule Occupancy, and Persistence of Inoculant Strains: Key Factors in the Rhizobium-Legume Symbioses.
Frontiers in Plant Science,
12, Artikel 690567.
https://doi.org/10.3389/fpls.2021.690567
Najarzadeh, Z., Nielsen, J., Farzadfard, A., Sereikaite, V., Strømgaard, K.
, Meyer, R. L. & Otzen, D. E. (2021).
Human Fibrinogen Inhibits Amyloid Assembly of Most Phenol-Soluble Modulins from Staphylococcus aureus.
ACS Omega,
6(34), 21960-21970.
https://doi.org/10.1021/acsomega.1c02333
Selas, A., Fuertes, M., Melcón-Fernández, E., Pérez-Pertejo, Y., Reguera, R. M., Balaña-Fouce, R.
, Knudsen, B. R., Palacios, F. & Alonso, C. (2021).
Hybrid quinolinyl phosphonates as heterocyclic carboxylate isosteres: Synthesis and biological evaluation against topoisomerase 1B (TOP1B).
Pharmaceuticals,
14(8), Artikel 784.
https://doi.org/10.3390/ph14080784
Taschner, M., Basquin, J., Steigenberger, B., Schäfer, I. B., Soh, Y. M., Basquin, C.
, Lorentzen, E., Räschle, M., Scheltema, R. A. & Gruber, S. (2021).
Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding.
EMBO Journal,
40(15), Artikel e107807.
https://doi.org/10.15252/embj.2021107807Strom, N. I., Grove, J., Meier, S. M., Bækvad-Hansen, M.
, Becker Nissen, J., Damm Als, T., Halvorsen, M., Nordentoft, M.
, Mortensen, P. B., Hougaard, D. M., Werge, T.
, Mors, O., Børglum, A. D., Crowley, J. J., Bybjerg-Grauholm, J.
& Mattheisen, M. (2021).
Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis.
Frontiers in Genetics,
12, Artikel 711624.
https://doi.org/10.3389/fgene.2021.711624
Winters, J., Kobek-Kjeldager, C., Foldager, L. & Pedersen, L. J. (2021).
Preliminary results on the effect of keeping pigs in home environment post weaning. I E. Strandberg, L. Pinotti, S. Messori, D. Kenny, M. Lee, J. F. Hocquette, V. A. P. Cadavez, S. Millet, R. Evans, T. Veldkamp, M. Pastell & G. Pollott (red.),
Book of Abstracts of the 72nd Annual Meeting of the European Federation of Animal Science (s. 356-356). Wageningen Academic Publishers.
https://doi.org/10.3920/978-90-8686-918-3
Christensen, M., Petersen, J. L., Sivanandam, P., Kronborg, C. S., Knudsen, U. B. & Martensen, P. M. (2021).
Reduction of serum-induced endothelial STAT3(Y705) activation is associated with preeclampsia.
Pregnancy Hypertension,
25, 103-109.
https://doi.org/10.1016/j.preghy.2021.05.012
Vandestadt, C.
, Vanwalleghem, G. C., Khabooshan, M. A., Douek, A. M., Castillo, H. A., Li, M., Schulze, K., Don, E., Stamatis, S. A., Ratnadiwakara, M., Änkö, M. L., Scott, E. K. & Kaslin, J. (2021).
RNA-induced inflammation and migration of precursor neurons initiates neuronal circuit regeneration in zebrafish.
Developmental Cell,
56(16), 2364-2380.e8.
https://doi.org/10.1016/j.devcel.2021.07.021Shemesh, M., Aktepe, T. E., Deerain, J. M., McAuley, J. L., Audsley, M. D., David, C. T., Purcell, D. F. J., Urin, V.
, Hartmann, R., Moseley, G. W., Mackenzie, J. M., Schreiber, G. & Harari, D. (2021).
SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon.
PLoS Pathogens,
17(8), Artikel e1009800.
https://doi.org/10.1371/journal.ppat.1009800Petersen, K. V., Selas, A.
, Hymøller, K. M., Mizielinski, K.
, Thorsager, M., Stougaard, M., Alonso, C., Palacios, F., Pérez-Pertejo, Y., Reguera, R. M., Balaña-Fouce, R.
, Knudsen, B. R. & Tesauro, C. (2021).
Simple and fast DNA based sensor system for screening of small-molecule compounds targeting eukaryotic topoisomerase 1.
Pharmaceutics,
13(8), Artikel 1255.
https://doi.org/10.3390/pharmaceutics13081255
Zhang, N.
, Kisiswa, L., Ramanujan, A., Li, Z., Sim, E. W., Tian, X., Yuan, W., Ibáñez, C. F. & Lin, Z. (2021).
Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains.
Journal of Biological Chemistry,
297(2), Artikel 100916.
https://doi.org/10.1016/j.jbc.2021.100916Timcenko, M., Dieudonné, T., Montigny, C.
, Boesen, T., Lyons, J. A., Lenoir, G.
& Nissen, P. (2021).
Structural Basis of Substrate-Independent Phosphorylation in a P4-ATPase Lipid Flippase.
Journal of Molecular Biology,
433(16), Artikel 167062.
https://doi.org/10.1016/j.jmb.2021.167062
Hansen, S. B., Dyla, M., Neumann, C., Quistgaard, E. M. H., Andersen, J. L., Kjaergaard, M. & Nissen, P. (2021).
The Crystal Structure of the Ca2+-ATPase 1 from Listeria monocytogenes reveals a Pump Primed for Dephosphorylation.
Journal of Molecular Biology,
433(16), Artikel 167015.
https://doi.org/10.1016/j.jmb.2021.167015
Rogato, A., Valkov, V. T.
, Nadzieja, M., Stougaard, J. & Chiurazzi, M. (2021).
The lotus japonicus AFB6 gene is involved in the auxin dependent root developmental program.
International Journal of Molecular Sciences ,
22(16), Artikel 8495.
https://doi.org/10.3390/ijms22168495Lee, Y.-L., Takeda, H., Moreira, G. C. M., Karim, L., Mullaart, E., Coppieters, W., GplusE Consortium, Appeltant, R., Veerkamp, R. F., Groenen, M. A. M., Georges, M., Bosse, M., Druet, T., Bouwman, A. C. & Charlier, C. (2021).
A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle.
PLoS Genetics,
17(7), Artikel e1009331.
https://doi.org/10.1371/journal.pgen.1009331Jakobsen, A.-K., Keller-Socin, J. G., Gonzales, M., Martín-Encinas, E., Palacios, F., Alonso, C.
, Knudsen, B. R. & Stougaard, M. (2021).
A Dual-Sensor-Based Screening System for In Vitro Selection of TDP1 Inhibitors.
Sensors,
21(14), Artikel 4832.
https://doi.org/10.3390/s21144832
Fernandez-Cantos, M. V.
, Garcia-Morena, D., Iannone, V., El-Nezami, H., Kolehmainen, M. & Kuipers, O. P. (2021).
Role of microbiota and related metabolites in gastrointestinal tract barrier function in NAFLD.
Tissue Barriers,
9(3), 1879719. Artikel 1879719.
https://doi.org/10.1080/21688370.2021.1879719Christensen, K. J.
, Dreier, J. W., Skotte, L., Feenstra, B.
, Grove, J., Børglum, A., Mitrovic, M., Cotsapas, C.
& Christensen, J. (2021).
Birth characteristics and risk of febrile seizures.
Acta Neurologica Scandinavica,
144(1), 51-57.
https://doi.org/10.1111/ane.13420Harwood, S. L., Nielsen, N. S., Diep, K., Jensen, K. T., Nielsen, P. K., Yamamoto, K.
& Enghild, J. J. (2021).
Development of selective protease inhibitors via engineering of the bait region of human α2-macroglobulin.
The Journal of Biological Chemistry,
297(1), Artikel 100879.
https://doi.org/10.1016/j.jbc.2021.100879
Ferreira, N., Gram, H., Sorrentino, Z. A.
, Gregersen, E., Schmidt, S. I.
, Reimer, L., Betzer, C., Perez-Gozalbo, C.
, Beltoja, M., Nagaraj, M., Wang, J., Nowak, J. S., Dong, M., Willén, K., Cholak, E.
, Bjerregaard-Andersen, K., Mendez, N., Rabadia, P., Shahnawaz, M.
... Jensen, P. H. (2021).
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.
Acta Neuropathologica,
142, 87-115.
https://doi.org/10.1007/s00401-021-02316-0
Nielsen, N. S., Gadeberg, T. A. F., Poulsen, E. T., Harwood, S. L., Weberskov, C. E., Pedersen, J. S., Andersen, G. R. & Enghild, J. J. (2021).
Mutation-induced dimerization of transforming growth factor-β-induced protein may drive protein aggregation in granular corneal dystrophy.
The Journal of Biological Chemistry,
297(1), Artikel 100858.
https://doi.org/10.1016/j.jbc.2021.100858
Walther, R., Monge, P., Pedersen, A., Benderoth, A., Pedersen, J., Farzadfard, A., Mandrup, O., Howard, K., Otzen, D. & Zelikin, A. N. (2021).
Per-glycosylation of the Surface-Accessible Lysines: One-Pot Aqueous Route to Stabilized Proteins with Native Activity.
ChemBioChem,
22(14), 2478-2485.
https://doi.org/10.1002/cbic.202100228
Monrad, I., Sahlertz, S. R.
, Nielsen, S. S. F., Pedersen, L. Ø.
, Petersen, M. S., Kobel, C. M., Tarpgaard, I. H., Storgaard, M., Mortensen, K. L., Schleimann, M. H., Tolstrup, M. & Vibholm, L. K. (2021).
Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Host Displaying Treatment Induced Viral Evolution.
Open Forum Infectious Diseases,
8(7), Artikel ofab295.
https://doi.org/10.1093/ofid/ofab295
Sweet, M. E.
, Larsen, C., Zhang, X., Schlame, M.
, Pedersen, B. P. & Stokes, D. L. (2021).
Structural basis for potassium transport in prokaryotes by KdpFABC.
Proceedings of the National Academy of Sciences (PNAS),
118(29), Artikel e2105195118.
https://doi.org/10.1073/pnas.2105195118Björnsdotter, E.
, Nadzieja, M., Chang, W.
, Escobar-Herrera, L., Mancinotti, D., Angra, D., Xia, X., Tacke, R., Khazaei, H., Crocoll, C., Vandenberg, A., Link, W., Stoddard, F. L., O'Sullivan, D. M.
, Stougaard, J., Schulman, A. H.
, Andersen, S. U. & Geu-Flores, F. (2021).
VC1 catalyses a key step in the biosynthesis of vicine in faba bean.
Nature Plants,
7(7), 923-931.
https://doi.org/10.1038/s41477-021-00950-wDel Amo-Maestro, L., Sagar, A., Pompach, P., Goulas, T.
, Scavenius, C., Ferrero, D. S., Castrillo-Briceño, M., Taulés, M.
, Enghild, J. J., Bernadó, P. & Gomis-Rüth, F. X. (2021).
An Integrative Structural Biology Analysis of Von Willebrand Factor Binding and Processing by ADAMTS-13 in Solution.
Journal of Molecular Biology,
433(13), Artikel 166954.
https://doi.org/10.1016/j.jmb.2021.166954Prokhorova, E., Agnew, T., Wondisford, A. R., Tellier, M., Kaminski, N., Beijer, D., Holder, J., Groslambert, J., Suskiewicz, M. J., Zhu, K., Reber, J. M., Krassnig, S. C., Palazzo, L., Murphy, S.
, Nielsen, M. L., Mangerich, A., Ahel, D., Baets, J., O'Sullivan, R. J. & Ahel, I. (2021).
Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease.
Molecular Cell,
81(12), 2640-2655.e8.
https://doi.org/10.1016/j.molcel.2021.04.028Olivieri, D., Castelli, E.
, Kawamura, Y. K., Papasaikas, P., Lukonin, I., Rittirsch, M., Hess, D., Smallwood, S. A., Stadler, M. B., Peters, A. H. F. M. & Betschinger, J. (2021).
Cooperation between HDAC3 and DAX1 mediates lineage restriction of embryonic stem cells.
EMBO Journal,
40(12), e106818. Artikel e106818.
https://doi.org/10.15252/embj.2020106818Jensen, R. K., Bajic, G., Sen, M., Springer, T. A.
, Vorup-Jensen, T. & Andersen, G. R. (2021).
Complement receptor 3 forms a compact high-affinity complex with iC3b.
Journal of Immunology,
206(12), 3032-3042.
https://doi.org/10.4049/jimmunol.2001208
Yang, C., Zhou, Y., Marcus, S., Formenti, G., Bergeron, L. A., Song, Z., Bi, X.
, Bergman, J., Rousselle, M. M. C., Zhou, C., Zhou, L., Deng, Y., Fang, M., Xie, D., Zhu, Y., Tan, S., Mountcastle, J., Haase, B., Balacco, J. ... Zhang, G. (2021).
Evolutionary and biomedical insights from a marmoset diploid genome assembly.
Nature,
594(7862), 227-233.
https://doi.org/10.1038/s41586-021-03535-xMartin, J., Khramtsova, E. A., Goleva, S. B., Blokland, G. A. M., Traglia, M., Walters, R. K.
, Hübel, C., Coleman, J. R. I., Breen, G.
, Børglum, A. D., Demontis, D., Grove, J., Werge, T., Bralten, J., Bulik, C. M., Lee, P. H., Mathews, C. A., Peterson, R. E., Winham, S. J. ... Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium (2021).
Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits.
Biological Psychiatry,
89(12), 1127-1137.
https://doi.org/10.1016/j.biopsych.2020.12.024Martín-Encinas, E., Rubiales, G.
, Knudsen, B. R., Palacios, F. & Alonso, C. (2021).
Fused chromeno and quinolino[1,8]naphthyridines: Synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents.
Bioorganic and Medicinal Chemistry,
40, Artikel 116177.
https://doi.org/10.1016/j.bmc.2021.116177Mullins, N., Forstner, A. J., O'Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z.
, Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., Charney, A. W., Drange, O. K., Gandal, M. J., Hagenaars, S. P., Ikeda, M., Kamitaki, N., Kim, M., Krebs, K., Panagiotaropoulou, G. ... HUNT All-In Psychiatry (2021).
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
Nature Genetics,
53(6), 817-829.
https://doi.org/10.1038/s41588-021-00857-4Cheng, Z., Buggiotti, L., Salavati, M., Marchitelli, C., Palma-Vera, S., Wylie, A., Takeda, H., Tang, L., Crowe, M. A., Wathes, D. C. & GplusE Consortium (2021).
Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis.
Molecular Biology Reports,
48, 4611-4623.
https://doi.org/10.1007/s11033-021-06494-8Milanetti, E., Miotto, M., Di Rienzo, L.
, Nagaraj, M., Monti, M.
, Golbek, T. W., Gosti, G.
, Roeters, S. J., Weidner, T., Otzen, D. E. & Ruocco, G. (2021).
In-Silico Evidence for a Two Receptor Based Strategy of SARS-CoV-2.
Frontiers in Molecular Biosciences,
8, Artikel 690655.
https://doi.org/10.3389/fmolb.2021.690655Otzen, D. E., Dueholm, M. S.
, Najarzadeh, Z., Knowles, T. P. J. & Ruggeri, F. S. (2021).
In situ Sub-Cellular Identification of Functional Amyloids in Bacteria and Archaea by Infrared Nanospectroscopy.
Small Methods,
5(6), Artikel 2001002.
https://doi.org/10.1002/smtd.202001002
Albiñana, C., Grove, J., McGrath, J. J., Agerbo, E., Wray, N. R., Bulik, C. M., Nordentoft, M., Hougaard, D. M., Werge, T.
, Børglum, A. D., Mortensen, P. B., Privé, F. & Vilhjálmsson, B. J. (2021).
Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction.
American Journal of Human Genetics,
108(6), 1001-1011.
https://doi.org/10.1016/j.ajhg.2021.04.014
Krissanaprasit, A., Key, C. M., Froehlich, K., Pontula, S., Mihalko, E.
, Dupont, D. M., Andersen, E. S., Kjems, J., Brown, A. C. & LaBean, T. H. (2021).
Multivalent Aptamer-Functionalized Single-Strand RNA Origami as Effective, Target-Specific Anticoagulants with Corresponding Reversal Agents.
Advanced Healthcare Materials,
10(11), Artikel 2001826.
https://doi.org/10.1002/adhm.202001826Li, R. Q., Jiang, M., Huang, J. Z.
, Møller, I. M. & Shu, Q. Y. (2021).
Mutations of the Genomes Uncoupled 4 Gene Cause ROS Accumulation and Repress Expression of Peroxidase Genes in Rice.
Frontiers in Plant Science,
12, Artikel 682453.
https://doi.org/10.3389/fpls.2021.682453
