Nielsen, J., Brandt, J.
, Boesen, T., Hummelshøj, T., Slaaby, R., Schluckebier, G.
& Nissen, P. (2022).
Structural investigations of full-length insulin receptor dynamics and signalling.
Journal of Molecular Biology,
434(5), Artikel 167458.
https://doi.org/10.1016/j.jmb.2022.167458
Bisiak, F., Chrenková, A., Zhang, S. D.
, Pedersen, J. N., Otzen, D. E., Zhang, Y. E.
& Brodersen, D. E. (2022).
Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response.
Journal of Biological Chemistry,
298(7), Artikel 102142.
https://doi.org/10.1016/j.jbc.2022.102142
Braunger, K., Ahn, J., Jore, M. M., Johnson, S., Tang, T. T. L.
, Pedersen, D. V., Andersen, G. R. & Lea, S. M. (2022).
Structure and function of a family of tick-derived complement inhibitors targeting properdin.
Nature Communications,
13, Artikel 317.
https://doi.org/10.1038/s41467-021-27920-2
Hartmann, S.
, Ling, M., Dreyer, L. S. A., Zipori, A.
, Finster, K., Grawe, S.
, Jensen, L. Z., Borck, S., Reicher, N., Niedermeier, D.
, Jones, N. C., Hoffmann, S. V., Wex, H., Rudich, Y.
, Boesen, T. & Santl-Temkiv, T. (2022).
Structure and Protein-Protein Interactions of Ice Nucleation Proteins Drive Their Activity.
Frontiers in Microbiology,
13, Artikel 872306.
https://doi.org/10.3389/fmicb.2022.872306
Gerlach, P.
, Garland, W., Lingaraju, M., Salerno-Kochan, A., Bonneau, F., Basquin, J.
, Jensen, T. H. & Conti, E. (2022).
Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Molecular Cell,
82(13), 2505-2518.e7.
https://doi.org/10.1016/j.molcel.2022.04.011
Pedersen, H., Jensen, R. K., Hansen, A. G., Petersen, S. V., Thiel, S., Laursen, N. S. & Andersen, G. R. (2022).
Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity.
Frontiers in Immunology,
13, Artikel 872536.
https://doi.org/10.3389/fimmu.2022.872536
Langousis, G., Cavadini, S.
, Boegholm, N., Lorentzen, E., Kempf, G. & Matthias, P. (2022).
Structure of the ciliogenesis-associated CPLANE complex.
Science Advances,
8(15), Artikel eabn0832.
https://doi.org/10.1126/sciadv.abn0832
Kobberø, S. D., Gajhede, M., Mirza, O. A.
, Kløverpris, S., Kjær, T. R., Mikkelsen, J. H., Boesen, T. & Oxvig, C. (2022).
Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism.
Nature Communications,
13(1), Artikel 6084.
https://doi.org/10.1038/s41467-022-33698-8
Ung, K. L., Winkler, M., Schulz, L., Kolb, M., Janacek, D. P.
, Dedic, E., Stokes, D. L., Hammes, U. Z.
& Pedersen, B. P. (2022).
Structures and mechanism of the plant PIN-FORMED auxin transporter.
Nature,
609(7927), 605-610.
https://doi.org/10.1038/s41586-022-04883-y
Fuertes, M., Selas, A., Trejo, A.
, Knudsen, B. R., Palacios, F. & Alonso, C. (2022).
Synthesis of hybrid phosphorated indenoquinolines and biological evaluation as topoisomerase I inhibitors and antiproliferative agents.
Bioorganic and Medicinal Chemistry Letters,
57, Artikel 128517.
https://doi.org/10.1016/j.bmcl.2021.128517
Jakobsen, A. K., Yuusufi, S., Madsen, L. B., Meldgaard, P., Knudsen, B. R. & Stougaard, M. (2022).
TDP1 and TOP1 as targets in anticancer treatment of NSCLC: Activity and protein level in normal and tumor tissue from 150 NSCLC patients correlated to clinical data.
Lung Cancer,
164, 23-32.
https://doi.org/10.1016/j.lungcan.2021.12.010,
https://doi.org/10.1016/j.lungcan.2021.12.010
Thodberg, K., Foldager, L., Fogsgaard, K. K., Gaillard, C. & Herskin, M. S. (2022).
Temperature conditions during commercial transportation of cull sows to slaughter.
Computers and Electronics in Agriculture,
192, Artikel 106626.
https://doi.org/10.1016/j.compag.2021.106626
Yang, A.
, Bofill-De Ros, X., Stanton, R., Shao, T. J., Villanueva, P. & Gu, S. (2022).
TENT2, TUT4, and TUT7 selectively regulate miRNA sequence and abundance.
Nature Communications,
13(1), Artikel 5260.
https://doi.org/10.1038/s41467-022-32969-8
Rasmussen, H. Ø., Wollenberg, D. T. W.
, Wang, H., Andersen, K. K., Oliveira, C. L. P., Jørgensen, C. I., Jørgensen, T. J. D.
, Otzen, D. E. & Pedersen, J. S. (2022).
The changing face of SDS denaturation: Complexes of Thermomyces lanuginosus lipase with SDS at pH 4.0, 6.0 and 8.0.
Journal of Colloid and Interface Science,
614, 214-232.
https://doi.org/10.1016/j.jcis.2021.12.188
Harwood, S. L., Diep, K., Nielsen, N. S., Jensen, K. T. & Enghild, J. J. (2022).
The conformational change of the protease inhibitor α2-macroglobulin is triggered by the retraction of the cleaved bait region from a central channel.
Journal of Biological Chemistry,
298(8), Artikel 102230.
https://doi.org/10.1016/j.jbc.2022.102230
Farzadfard, A., Pedersen, J. N., Meisl, G.
, Somavarapu, A. K., Alam, P., Goksøyr, L., Nielsen, M. A., Sander, A. F., Knowles, T. P. J.
, Pedersen, J. S. & Otzen, D. E. (2022).
The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization.
Communications Biology,
5(1), Artikel 123.
https://doi.org/10.1038/s42003-022-03059-8
Wigdor, E. M., Weiner, D. J.
, Grove, J., Fu, J. M.
, Thompson, W. K., Carey, C. E., Baya, N., van der Merwe, C., Walters, R. K., Satterstrom, F. K., Palmer, D. S., Rosengren, A., Bybjerg-Grauholm, J., Hougaard, D. M.
, Mortensen, P. B., Daly, M. J., Talkowski, M. E., Sanders, S. J., Bishop, S. L. ... iPSYCH Consortium (2022).
The female protective effect against autism spectrum disorder.
Cell Genomics,
2(6), Artikel 100134.
https://doi.org/10.1016/j.xgen.2022.100134
Mogensen, E. H., Poulsen, E. T., Thøgersen, I. B., Yamamoto, K.
, Brüel, A. & Enghild, J. J. (2022).
The low-density lipoprotein receptor-related protein 1 (LRP1) interactome in the human cornea.
Experimental Eye Research,
219, Artikel 109081.
https://doi.org/10.1016/j.exer.2022.109081
Bergeron, L. A.
, Besenbacher, S., Turner, T. N., Versoza, C. J., Wang, R. J., Price, A. L., Armstrong, E.
, Riera, M., Carlson, J., Chen, H. Y., Hahn, M. W., Harris, K.
, Kleppe, A. S., López-Nandam, E. H., Moorjani, P., Pfeifer, S. P., Tiley, G. P., Yoder, A. D., Zhang, G.
& Schierup, M. H. (2022).
The mutationathon highlights the importance of reaching standardization in estimates of pedigree-based germline mutation rates.
eLife,
11, Artikel e73577.
https://doi.org/10.7554/eLife.73577
Fruergaard, M. U., Dach, I., Andersen, J. L., Ozol, M., Shasavar, A., Quistgaard, E. M. H., Poulsen, H., Fedosova, N. & Nissen, P. (2022).
The Na,K-ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state. Journal of Biological Chemistry,
298(9), Artikel 102317.
https://doi.org/10.1016/j.jbc.2022.102317
Salimi, M., Tabasi, F.
, Nazari, M., Ghazvineh, S. & Raoufy, M. R. (2022).
The olfactory bulb coordinates the ventral hippocampus–medial prefrontal cortex circuit during spatial working memory performance.
Journal of Physiological Sciences,
72(1), Artikel 9.
https://doi.org/10.1186/s12576-022-00833-5
Frank, M., Cortleven, A., Pěnčík, A., Novak, O. & Schmülling, T. (2022).
The Photoperiod Stress Response in Arabidopsis thaliana Depends on Auxin Acting as an Antagonist to the Protectant Cytokinin.
International Journal of Molecular Sciences ,
23(6), Artikel 2936.
https://doi.org/10.3390/ijms23062936
Møhlenberg, M., Eriksen, P. L., Laursen, T. L., Nielsen, M. B., Hamilton-Dutoit, S. J., Grønbæk, H., Hartmann, R. & Thomsen, K. L. (2022).
The presence of interferon affects the progression of non-alcoholic fatty liver disease.
Genes and Immunity,
23(5), 157–165.
https://doi.org/10.1038/s41435-022-00176-6
Khateb, H., Sørensen, R. S., Cramer, K., Eklund, A. S.
, Kjems, J., Meyer, R. L., Jungmann, R.
& Sutherland, D. S. (2022).
The Role of Nanoscale Distribution of Fibronectin in the Adhesion of Staphylococcus aureus Studied by Protein Patterning and DNA-PAINT.
ACS Nano,
16(7), 10392-10403.
https://doi.org/10.1021/acsnano.2c00630
Gu, T., Just, J., Stenz, K. T., Yan, Y., Sieljacks, P., Wang, J., Groennebaek, T. S., Jakobsgaard, J. E., Rindom, E., Herskind, J., Gravholt, A.
, Lassen, T. R., Jørgensen, M., Bæk, R.
, Gutiérrez-Jiménez, E., Iversen, N. K., Rasmussen, P. M., Nyengaard, J. R., Jørgensen, M. M.
... Drasbek, K. R. (2022).
The Role of Plasma Extracellular Vesicles in Remote Ischemic Conditioning and Exercise-Induced Ischemic Tolerance.
International Journal of Molecular Sciences ,
23(6), Artikel 3334.
https://doi.org/10.3390/ijms23063334
Hansen, E. K. B., Fredsøe, J. H., Okholm, T. L. H., Ulhøi, B. P., Klingenberg, S., Jensen, J. B., Kjems, J., Bouchelouche, K., Borre, M., Damgaard, C. K., Pedersen, J. S., Kristensen, L. S. & Sørensen, K. D. (2022).
The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer.
Genome Medicine,
14(1), Artikel 8.
https://doi.org/10.1186/s13073-021-01009-3
Keller, J. G., Hymøller, K. M., Thorsager, M. E., Hansen, N. Y., Erlandsen, J. U., Tesauro, C., Simonsen, A. K. W., Andersen, A. B., Vandsø Petersen, K., Holm, L. L.
, Stougaard, M., Andresen, B. S., Kristensen, P., Frøhlich, R.
& Knudsen, B. R. (2022).
Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation.
Nucleic Acids Research,
50(11), 6332-6342.
https://doi.org/10.1093/nar/gkac482
Cheng, Z., Palma-Vera, S., Buggiotti, L., Salavati, M., Becker, F., Werling, D., Wathes, D. C. & GplusE Consortium (2022).
Transcriptomic analysis of circulating leukocytes obtained during the recovery from clinical mastitis caused by escherichia coli in Holstein dairy cows.
Animals,
12(16), 1-22. Artikel 2146.
https://doi.org/10.3390/ani12162146
Greve, A. N., Jepsen, J. R. M., Mortensen, E. L., Uher, R., Mackenzie, L.
, Foldager, L., Gantriis, D., Burton, B. K., Ellersgaard, D., Christiani, C. J., Spang, K. S., Hemager, N., Uddin, J., Henriksen, M. T.
, Zahle, K. K., Stadsgaard, H., Plessen, K. J., Thorup, A. A. E., Nordentoft, M.
... Bliksted, V. (2022).
Transmission of intelligence, working memory, and processing speed from parents to their seven-year-old offspring is function specific in families with schizophrenia or bipolar disorder.
Schizophrenia Research,
246, 195-201.
https://doi.org/10.1016/j.schres.2022.06.032
Tapia-Galisteo, A., Sánchez Rodríguez, Í., Aguilar-Sopeña, O.
, Harwood, S. L., Narbona, J., Ferreras Gutierrez, M., Navarro, R., Martín-García, L., Corbacho, C., Compte, M., Lacadena, J., Blanco, F. J., Chames, P., Roda-Navarro, P., Álvarez-Vallina, L. & Sanz, L. (2022).
Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer.
OncoImmunology,
11(1), Artikel 2034355.
https://doi.org/10.1080/2162402X.2022.2034355
Hangiu, O., Compte, M.
, Dinesen, A., Navarro, R., Tapia-Galisteo, A.
, Mandrup, O. A., Erce-Llamazares, A., Lázaro-Gorines, R., Nehme-Álvarez, D., Domínguez-Alonso, C.
, Harwood, S. L., Alfonso, C., Blanco, B., Rubio-Pérez, L., Jiménez-Reinoso, A., Díez-Alonso, L., Blanco, F. J., Sanz, L.
, Howard, K. A. & Álvarez-Vallina, L. (2022).
Tumor targeted 4-1BB agonist antibody-albumin fusions with high affinity to FcRn induce anti-tumor immunity without toxicity.
iScience,
25(9), Artikel 104958.
https://doi.org/10.1016/j.isci.2022.104958
Verzelli, P., Nold, A.
, Sun, C., Heilemann, M., Schuman, E. M. & Tchumatchenko, T. (2022).
Unbiased choice of global clustering parameters for single-molecule localization microscopy.
Scientific Reports,
12(1), 22561. Artikel 22561.
https://doi.org/10.1038/s41598-022-27074-1
Meisl, G., Xu, C. K., Taylor, J. D., Michaels, T. C. T., Levin, A.
, Otzen, D., Klenerman, D., Matthews, S., Linse, S.
, Andreasen, M. & Knowles, T. P. J. (2022).
Uncovering the universality of self-replication in protein aggregation and its link to disease.
Science Advances,
8(32), Artikel eabn6831.
https://doi.org/10.1126/sciadv.abn6831
Kobek-Kjeldager, C., Jensen, L. D., Foldager, L., Kaiser, M., Thodberg, K. & Herskin, M. S. (2022).
Validation of behavioural sampling techniques for 20-25 kg pigs during 23-hour transport. I M. Kjosevski, S. Waiblinger & V. Ilieski (red.),
Proceedings of the 55th Congress of the ISAE: Animal Behaviour and Beyond (s. 167-167).
https://www.applied-ethology.org/res/ISAE_2022_PROCEEDINGS_e-version.pdf
Neumann, C., Focht, D., Trampari, S., Lyons, J. A. & Nissen, P. (2022).
Variations on a theme: Crystal forms of the amino-acid transporter MhsT.
Acta Crystallographica Section F: Structural Biology Communications,
78(Part 8), 297-305.
https://doi.org/10.1107/S2053230X22007154
Fukai, E., Yoshikawa, M.
, Shah, N., Sandal, N., Miyao, A., Ono, S., Hirakawa, H.
, Akyol, T. Y., Umehara, Y., Nonomura, K.-I.
, Stougaard, J., Hirochika, H., Hayashi, M., Sato, S.
, Andersen, S. U. & Okazaki, K. (2022).
Widespread and transgenerational retrotransposon activation in inter- and intra-species recombinant inbred populations of Lotus japonicus.
The Plant Journal,
111(5), 1397-1410.
https://doi.org/10.1111/tpj.15896