Department of Molecular Biology and Genetics

Aarhus University Seal

Gilles Vanwalleghem
[Translate to English:] Legend: The six days old larval zebrafish expresses a fluorescent calcium reporter in all of its neurons, including in the enteric nervous system that regulates the gut. We use this transparent animal to image in vivo the activity of its neurons. Arrows indicate the rostral, dorsal, caudal, and ventral directions. Scale bar is 100 um.
Video legend: Live imaging of the activity of neurons in the guts of a six days old larval zebrafish, we can see the high motility of the guts driven by the waves of neuronal activity.

Featured articles

  • “Brain-wide mapping of water flow perception in zebrafish.” Vanwalleghem G, Schuster K, Taylor MA, Favre-Bulle IA, Scott EK. Journal of Neuroscience, doi: 10.1523/JNEUROSCI.0049-20.2020 (2020)
  • “Cellular resolution imaging of vestibular processing across the larval zebrafish brain” Favre-Bulle IA*, Vanwalleghem GC*, Taylor MA, Rubinsztein-Dunlop H, Scott EK. Current Biology. doi: 10.1016/j.cub.2018.09.060. (2018)
  • “Integrative whole-brain neuroscience in larval zebrafish" Vanwalleghem G, Ahrens MB and Scott EK. Current Opinion in Neurobiology. doi: 10.1016/j.conb.2018.02.004 (2018)

Peer-reviewed publications

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Mancienne, T., Marquez-Legorreta, E., Piber, M., Wilde, M., Vanwalleghem, G., Favre-Bulle, I. & Scott, E. K. (2026). Visual Threat Location Impacts Brain-Wide Visual Adaptation Networks. Journal of Comparative Neurology, 534(7), Article e70182. https://doi.org/10.1002/cne.70182
Machelart, A., Van Vyve, M., Potemberg, G., Demars, A., De Trez, C., Tima, H. G., Vanwalleghem, G., Romano, M., Truyens, C., Letesson, J. J. & Muraille, E. (2017). Trypanosoma infection favors Brucella elimination via IL-12/IFNγ-dependent pathways. Frontiers in Immunology, 8(JUL), Article 903. https://doi.org/10.3389/fimmu.2017.00903
Lecordier, L., Uzureau, S., Vanwalleghem, G., Deleu, M., Crowet, J. M., Barry, P., Moran, B., Voorheis, P., Dumitru, A. C., Yamaryo-Botté, Y., Dieu, M., Tebabi, P., Vanhollebeke, B., Lins, L., Botté, C. Y., Alsteens, D., Dufrêne, Y., Pérez-Morga, D., Nolan, D. P. & Pays, E. (2020). The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity. iScience, 23(9), Article 101476. https://doi.org/10.1016/j.isci.2020.101476
Hourez, R., Azdad, K., Vanwalleghem, G., Roussel, C., Gall, D. & Schiffmann, S. N. (2005). Activation of protein kinase C and inositol 1,4,5-triphosphate receptors antagonistically modulate voltage-gated sodium channels in striatal neurons. G E P, 1059(2), 189-196. https://doi.org/10.1016/j.brainres.2005.08.031
Heap, L. A. L., Vanwalleghem, G., Thompson, A. W., Favre-Bulle, I. A. & Scott, E. K. (2018). Luminance Changes Drive Directional Startle through a Thalamic Pathway. Neuron, 99(2), 293-301.e4. https://doi.org/10.1016/j.neuron.2018.06.013

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Revised 13.11.2025