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16.06.2020 | Nyhed

How to keep the nucleus clean

RNA turnover in the nuclei of eukaryotic cells is controlled by the RNA exosome aided by numerous cofactors. Researchers at Aarhus University and Copenhagen University now show how two major nuclear exosome cofactors recognize their RNA targets to keep a clean nuclear environment. This is important for the health of our cells – and thus humans.

16.06.2020 | Forskning

Regulering af RNA er afgørende for differentiering af stamceller

Nuclear RNA levels are kept in check by RNA decay factors. Now, researchers at Aarhus and Copenhagen Universities show that an excess of RNA in the nucleus can have negative effects on a crucial regulator of stem cell differentiation.