Institut for Molekylærbiologi og Genetik

Aarhus Universitets segl

List of Publications

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Nygaard, J. V., Andersen, M. Ø., Howard, K., Sasov, A., Kjems, J. & Besenbacher, F. (2004). Analysis of Nanoparticles in Scaffolds for Tissue Engineering by use of X-Ray Nano Tomography. Poster-session præsenteret på iNANO 4th annual meeting, Aarhus, Danmark.
Kjems, J., Liu, X., Howard, K. & Besenbacher, F. (2006). Nanoparticles for nuclear acid delivery.
Howard, K. A., Rahbek, U. L., Liu, X., Damgaard, C. K., Glud, S. Z., Andersen, M. Ø., Hovgaard, M. B., Schmitz, A., Nyengaard, J. R., Besenbacher, F. & Kjems, J. (2006). RNA interference in Vitro and in Vivo using a novel chitosan/siRNA nanoparticle system. Molecular Therapy, 14(4), 476-484. https://doi.org/10.1016/j.ymthe.2006.04.010
Xu, S., Dong, M., Liu, X., Howard, K. A., Kjems, J. & Besenbacher, F. (2007). Direct force measurements between siRNA and chitosan molecules using force spectroscopy. Biophysical Journal, 93(3), 952-9. https://doi.org/10.1529/biophysj.106.093229
Bak, R. O., Andersen, M. Ø., Howard, K. A. & Kjems, J. (2007). Localized Delivery of Lyophilized siRNA polyplexes. Poster-session præsenteret på INASCON, Aarhus, Danmark.
Howard, K. A., Dong, M., Oupicky, D., Bisht, H. S., Buss, C., Besenbacher, F. & Kjems, J. (2007). Nanocarrier stimuli-activated gene delivery. Small, 3(1), 54-7. https://doi.org/10.1002/smll.200600328
Howard, K. A. & Kjems, J. (2007). Polycation-based nanoparticle delivery for improved RNA interference therapeutics. Expert Opinion on Biological Therapy, 7(12), 1811-1822. https://doi.org/10.1517/14712598.7.12.1811
Howard, K. A. & Kjems, J. (2007). Polycation-based nanoparticle delivery for improved RNAi therapeutics. Expert Opin. Biol. Ther, 7, 1811-1822.
Andersen, M. Ø., Nygaard, J. V., Howard, K., Bak, R. O., Paludan, S. R., Raarup, M. K., Besenbacher, F. & Kjems, J. (2007). Surface delivery of siRNA for implants. European Cells & Materials, 14(3), 118.
Liu, X., Howard, K. A., Dong, M., Andersen, M. Ø., Rahbek, U. L., Johnsen, M. G., Hansen, O. C., Besenbacher, F. & Kjems, J. (2007). The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing. Biomaterials, 28(6), 1280-8. https://doi.org/10.1016/j.biomaterials.2006.11.004
Dong, M. D., Howard, K. A., Oupicky, D., Bisht, H., Kjems, J. & Besenbacher, F. (2007). Visualization of thermally activated nanocarriers using in situ atomic force microscopy: Nanotechnology. Nanotechnology, 18(18), Artikel 185501. https://doi.org/10.1088/0957-4484/18/18/185501
Howard, K. A., Paludan, S. R., Behlke, M. A., Besenbacher, F., Deleuran, B. W. & Kjems, J. (2008). Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model. Molecular Therapy, 17(1), 162-168. https://doi.org/10.1038/mt.2008.220
Andersen, M. Ø., Howard, K. A., Paludan, S. R., Besenbacher, F. & Kjems, J. (2008). Delivery of siRNA from lyophilized polymeric surfaces. Biomaterials, 29(4), 506-512. https://doi.org/10.1016/j.biomaterials.2007.10.003
Rahbek, U. L., Howard, K. A., Oupicky, D., Manickam, D. S., Dong, M., Nielsen, A. F., Hansen, T. B., Besenbacher, F. & Kjems, J. (2008). Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides. Journal of Gene Medicine, 10(1), 81-93. https://doi.org/10.1002/jgm.1120
Nygaard, J. V., Andersen, M. Ø., Howard, K. A., Foss, M., Bünger, C., Kjems, J. & Besenbacher, F. (2008). Investigation of particle-functionalized tissue engineering scaffolds using X-ray tomographic microscopy. Biotechnology and Bioengineering (Print), 100(4), 820-9. https://doi.org/10.1002/bit.21796
Hartmann, H., Lakner, U., Andersen, M. Ø., Kjems, J., Howard, K. A. & Schloßhauer, B. (2009). Carrier Matrix for siRNA-Mediated Gene Knock Down to Promote Neuronal Regeneration. Tissue Engineering. Part A. Tissue Engineering, (3), 718.
Mistry, A., Glud, S. Z., Kjems, J., Nyengaard, J. R., Howard, K. A., Stolnik, S. & Illum, L. (2009). Effect of physicochemical properties on intranasal nanoparticle transit into murine olfactory epithelium. Journal of Drug Evaluation, 17(7), 543-552. https://doi.org/10.1080/10611860903055470
Glud, S. Z., Bramsen, J. B., Dagnaes-Hansen, F., Wengel, J., Howard, K. A., Nyengaard, J. R. & Kjems, J. (2009). Naked siLNA-mediated gene silencing of lung bronchoepithelium EGFP expression after intravenous administration. Oligonucleotides, 19(2), 163-8. https://doi.org/10.1089/oli.2008.0175
Andersen, M. Ø., Howard, K. A. & Kjems, J. (2009). RNAi using a chitosan/siRNA nanoparticle system: in vitro and in vivo applications. I Methods in Molecular Biology (Bind 555, s. 77-86) https://doi.org/10.1007/978-1-60327-295-7_6
Larsen, E. K. U., Nielsen, T., Wittenborn, T., Birkedal, H., Vorup-Jensen, T., Jakobsen, M. H., Østergaard, L., Horsman, M. R., Besenbacher, F., Howard, K. A. & Kjems, J. (2009). Size-Dependent Accumulation of PEGylated Silane-Coated Magnetic Iron Oxide Nanoparticles in Murine Tumors. A C S Nano, 3(7), 1947-51. https://doi.org/10.1021/nn900330m

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Revideret 01.07.2026
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Viktor Hauge Ladegaard