Institut for Molekylærbiologi og Genetik

Aarhus Universitets segl

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Publications

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Tan, C. L., Plotkin, J. L., Venø, M. T., von Schimmelmann, M., Feinberg, P., Mann, S., Handler, A., Kjems, J., Surmeier, D. J., O’Carroll, D., Greengard, P. & Schaefer, A. (2013). MicroRNA-128 governs neuronal excitability and motor behavior in mice. Science, 342(6163), 1254-1258. https://doi.org/10.1126/science.1244193
Dang, J., Bian, Y., Sun, J., Chen, F., Dong, G.-Y., Liu, Q., Wang, X.-W., Kjems, J., Gao, S. & Wang, Q.-T. (2013). MicroRNA-137 promoter methylation in oral lichen planus and oral squamous cell carcinoma. Journal of Oral Pathology & Medicine, 42(4), 315-321. https://doi.org/10.1111/jop.12012
Wu, K., Song, W., Zhao, L., Liu, M., Yan, J., Andersen, M. Ø., Kjems, J., Gao, S. & Zhang, Y. (2013). MicroRNA functionalized microporous titanium oxide surface by lyophilization with enhanced osteogenic activity. A C S Applied Materials and Interfaces, 5(7), 2733-44. https://doi.org/10.1021/am400374c
Hua, Y., Larsen, N., Kalyana-Sundaram, S., Kjems, J., Chinnaiyan, A. M. & Peter, M. E. (2013). miRConnect 2.0: identification of oncogenic, antagonistic miRNA families in three human cancers. BMC Genomics, 14(179), 1-18. https://doi.org/10.1186/1471-2164-14-179
Hansen, T. B., Jensen, T. I., Clausen, B. H., Bramsen, J. B., Finsen, B., Damgaard, C. K. & Kjems, J. (2013). Natural RNA circles function as efficient microRNA sponges. Nature, 495, 384-388. https://doi.org/10.1038/nature11993
Quinones, J. P., Gothelf, K. V., Kjems, J., Caballero, A. M. H., Schmidt, C. & Covas, C. P. (2013). N,O6-partially acetylated chitosan nanoparticles hydrophobically-modified for controlled release of steroids and vitamin E. Carbohydrate Polymers, 91(1), 143-151. https://doi.org/10.1016/j.carbpol.2012.07.080
Quinones, J. P., Gothelf, K. V., Kjems, J., Heras, A., Schmidt, C. & Peniche, C. (2013). Novel Self-Assembled Nanoparticles of Testosterone-Modified Glycol Chitosan and Fructose Chitosan for Controlled Release. Journal of Biomaterials and Tissue Engineering, 3(1), 164-172. https://doi.org/10.1166/jbt.2013.1071
Iversen, F., Yang, C., Dagnæs-Hansen, F., Schaffert, D. H., Kjems, J. & Gao, S. (2013). Optimized siRNA-PEG Conjugates for Extended Blood Circulation and Reduced Urine Excretion in Mice. Theranostics, 3(3), 201-209. https://doi.org/10.7150/thno.5743
Nawroth, I., Alsner, J., Deleuran, B. W., Dagnæs-Hansen, F., Yang, C., Horsman, M. R., Overgaard, J., Howard, K., Kjems, J. & Gao, S. (2013). Peritoneal macrophages mediated delivery of chitosan/siRNA nanoparticle to the lesion site in a murine radiation-induced fibrosis model. Acta Oncologica, 52(8), 1730-1738. https://doi.org/10.3109/0284186X.2012.726373
Gonzalez, B. B., Dagnæs-Hansen, F., Fenton, R. A., Gao, S., Hein, S., Dong, M., Kjems, J. & Howard, K. A. (2013). Protection and systemic translocation of siRNA following oral administration of chitosan/siRNA nanoparticles. Molecular Therapy - Nucleic Acids, 2(1), 1-8. Artikel e76. https://doi.org/10.1038/mtna.2013.2
Farjami, E., Campos, R., Nielsen, J. S., Gothelf, K. V., Kjems, J. & Ferapontova, E. (2013). RNA aptamer-based electrochemical biosensor for selective and label-free analysis of dopamine. Analytical Chemistry, 85(1), 121-128. https://doi.org/10.1021/ac302134s
Beerens, N., Jepsen, M. D. E., Nechyporuk-Zloy, V., Krüger, A. C., Darlix, J.-L., Kjems, J. & Birkedal, V. (2013). Role of the primer activation signal in tRNA annealing onto the HIV-1 genome studied by single-molecule FRET microscopy. RNA, 19(4), 517-26. https://doi.org/10.1261/rna.035733.112
Quinones, J. P., Gothelf, K. V., Kjems, J., Yang, C., Caballero, A. M. H., Schmidt, C. & Peniche Covas, C. (2013). Self-assembled nanoparticles of modified-chitosan conjugates for the sustained release of dl-α-tocopherol. Carbohydrate Polymers, 92(1), 856-864. https://doi.org/10.1016/j.carbpol.2012.10.005
Andersen, M. Ø., Le, D. Q. S., Chen, M., Nygaard, J. V., Kassem, M., Bünger, C. & Kjems, J. (2013). Spatially Controlled Delivery of siRNAs to Stem Cells in Implants Generated by Multi-Component Additive Manufacturing. Advanced Functional Materials, 23(45), 5599-5607. https://doi.org/10.1002/adfm.201300832
Hansen, L., Unmack Larsen, E. K., Nielsen, E. H., Iversen, F., Liu, Z., Thomsen, K., Pedersen, M., Skrydstrup, T., Nielsen, N. C., Ploug, M. & Kjems, J. (2013). Targeting of peptide conjugated magnetic nanoparticles to urokinase plasminogen activator receptor (uPAR) expressing cells. Nanoscale, 5, 8192-8201. https://doi.org/10.1039/c3nr32922d
Andersen, M. Ø., Dillschneider, P. & Kjems, J. (2013). The Role of MicroRNAs in Natural Tissue Development and Application in Regenerative Medicine. I K. A. Howard (red.), RNA Interference from Biology to Therapeutics (s. 57-78). Springer. https://doi.org/10.1007/978-1-4614-4744-3_3
Kaalund, S. S., Venø, M. T., Bak, M., Møller, R. S., Laursen, H., Madsen, F., Broholm, H., Quistorff, B., Uldall, P., Tommerup, N., Kauppinen, S., Sabers, A., Fluiter, K., Møller, L. B., Nossent, A. Y., Silahtaroglu, A., Kjems, J., Aronica, E. & Tümer, Z. (2014). Aberrant expression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal sclerosis-Convergence on axonal guidance. Epilepsia, 55(12), 2017-2027. https://doi.org/10.1111/epi.12839
Wittenborn, T. R., Larsen, E. K. U., Nielsen, T., Rydtoft, L. M., Hansen, L., Nygaard, J. V., Vorup-Jensen, T., Kjems, J., Horsman, M. R. & Nielsen, N. C. (2014). Accumulation of nano-sized particles in a murine model of angiogenesis. Biochemical and Biophysical Research Communications, 443(2), 470-6. https://doi.org/10.1016/j.bbrc.2013.11.127
Nielsen, C., Kjems, J., Sorensen, K. R., Engelholm, L. H. & Behrendt, N. (2014). Advances in targeted delivery of small interfering RNA using simple bioconjugates. Expert Opinion on Drug Delivery, 11(5), 791-822. https://doi.org/10.1517/17425247.2014.896898
Ma, Z., Yang, C., Song, W., Wang, Q., Kjems, J. & Gao, S. (2014). Chitosan Hydrogel as siRNA vector for prolonged gene silencing. Journal of Nanobiotechnology, 12(23), 1-9. https://doi.org/10.1186/1477-3155-12-23

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Revideret 01.07.2026
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Viktor Hauge Ladegaard