The lab focuses on non-coding RNA in the nucleus of the cell. We are interested in how non-coding RNAs are processed and mediate its functions. Of particular interest is protein-RNA interactions.
We use molecular biology techniques, RNA sequencing and bioinformatics. We also develop state-of-the-art techniques to use for specific scientific questions within our core competences.
The main topics of the lab are processing and regulation of primary miRNA biogenesis and the role of long non-coding RNA in transcriptional regulation with emphasis on enhancers.
For some of our work on these topics see: