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Publikationer fra instituttet

Tidsskriftsforsider lavet af forskere fra MBG

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Chen, J., Bataillon, T., Glémin, S. & Lascoux, M. (2022). Hunting for Beneficial Mutations: Conditioning on SIFT Scores When Estimating the Distribution of Fitness Effect of New Mutations. Genome Biology and Evolution, 14(1), Artikel evab151. https://doi.org/10.1093/gbe/evab151

Nørgård, M., Steffensen, L. B., Hansen, D. R., Füchtbauer, E. M., Engelund, M. B., Dimke, H., Andersen, D. C. & Svenningsen, P. (2022). A new transgene mouse model using an extravesicular EGFP tag enables affinity isolation of cell-specific extracellular vesicles. Scientific Reports, 12, Artikel 496. https://doi.org/10.1038/s41598-021-04512-0

Mohammad-Beigi, H., Zanganeh, M., Scavenius, C., Eskandari, H., Farzadfard, A., Shojaosadati, S. A., Enghild, J. J., Otzen, D. E., Buell, A. K. & Sutherland, D. S. (2022). A Protein Corona Modulates Interactions of α-Synuclein with Nanoparticles and Alters the Rates of the Microscopic Steps of Amyloid Formation. ACS Nano, 16(1), 1102-1118. https://doi.org/10.1021/acsnano.1c08825

Nagaraj, M., Najarzadeh, Z., Pansieri, J., Biverstål, H., Musteikyte, G., Smirnovas, V., Matthews, S., Emanuelsson, C., Johansson, J., Buxbaum, J. N., Morozova-Roche, L. & Otzen, D. E. (2022). Chaperones mainly suppress primary nucleation during formation of functional amyloid required for bacterial biofilm formation. Chemical Science, 13(2), 536-553. https://doi.org/10.1039/d1sc05790a

Kitazawa, T., Minoux, M., Ducret, S. & Rijli, F. M. (2022). Different Ectopic Hoxa2 Expression Levels in Mouse Cranial Neural Crest Cells Result in Distinct Craniofacial Anomalies and Homeotic Phenotypes. Journal of Developmental Biology, 10(1), Artikel 9. https://doi.org/10.3390/jdb10010009

Wimberley, T., Brikell, I., Pedersen, E. M., Agerbo, E., Vilhjálmsson, B. J., Albiñana, C., Privé, F., Thapar, A., Langley, K., Riglin, L., Simonsen, M., Nielsen, H. S., Børglum, A. D., Nordentoft, M., Mortensen, P. B. & Dalsgaard, S. (2022). Early-Life Injuries and the Development of Attention-Deficit/Hyperactivity Disorder. Journal of Clinical Psychiatry, 83(1), Artikel 21m14033. https://doi.org/10.4088/JCP.21m14033

Schendel, D., Munk Laursen, T., Albiñana, C., Vilhjalmsson, B., Ladd-Acosta, C., Fallin, M. D., Benke, K., Lee, B., Grove, J., Kalkbrenner, A., Ejlskov, L., Hougaard, D., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Børglum, A. D., Werge, T., Nordentoft, M., Mortensen, P. B. & Agerbo, E. (2022). Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism. Autism Research, 15(1), 171-182. https://doi.org/10.1002/aur.2629

Larsen, K., Christensen, T. B., Højberg, O. & Sørensen, M. T. (2022). Exposure of pigs to glyphosate affects gene-specific DNA methylation and gene expression. Toxicology reports, 9, 298-310. https://doi.org/10.1016/j.toxrep.2022.02.007

Dahl, M., Husby, S., Eskelund, C. W., Besenbacher, S., Fjelstrup, S., Côme, C., Ek, S., Kolstad, A., Räty, R., Jerkeman, M., Geisler, C. H., Kjems, J., Kristensen, L. S. & Grønbæk, K. (2022). Expression patterns and prognostic potential of circular RNAs in mantle cell lymphoma: a study of younger patients from the MCL2 and MCL3 clinical trials. Leukemia, 36(1), 177-188. https://doi.org/10.1038/s41375-021-01311-4

Sønderby, T. V., Rasmussen, H. Ø., Frank, S. A., Skov Pedersen, J. & Otzen, D. E. (2022). Folding steps in the fibrillation of functional amyloid: denaturant sensitivity reveals common features in nucleation and elongation. Journal of Molecular Biology, 434(2), Artikel 167337. https://doi.org/10.1016/j.jmb.2021.167337

Petersen, G., Shyama Prasad Rao, R., Anderson, B., Zervas, A., Seberg, O., Rasmusson, A. G. & Max Møller, I. (2022). Genes from oxidative phosphorylation complexes II-V and two dual-function subunits of complex I are transcribed in Viscum album despite absence of the entire mitochondrial holo-complex I. Mitochondrion, 62, 1-12. https://doi.org/10.1016/j.mito.2021.10.006

Aminzadeh, A., Larsen, C. E., Boesen, T. & Jørgensen, R. (2022). High-resolution structure of native toxin A from Clostridioides difficile. EMBO Reports, 23(1), Artikel e53597. https://doi.org/10.15252/embr.202153597

Najarzadeh, Z., Mohammad-Beigi, H., Pedersen, J. N., Christiansen, G., Pedersen, J. S., Nielsen, J. & Otzen, D. E. (2022). Interaction of membrane vesicles with the Pseudomonas functional amyloid protein FapC facilitates amyloid formation. BBA advances, 2, Artikel 100055. https://doi.org/10.1016/j.bbadva.2022.100055

Ding, Y., Hou, K., Burch, K. S., Lapinska, S., Privé, F., Vilhjálmsson, B., Sankararaman, S. & Pasaniuc, B. (2022). Large uncertainty in individual polygenic risk score estimation impacts PRS-based risk stratification. Nature Genetics, 54(1), 30–39 . https://doi.org/10.1038/s41588-021-00961-5

Moeskjær, S., Skovbjerg, C. K., Tausen, M., Wind, R., Roulund, N., Janss, L. & Andersen, S. U. (2022). Major effect loci for plant size before onset of nitrogen fixation allow accurate prediction of yield in white clover. Theoretical and Applied Genetics, 135(1), 125-143. https://doi.org/10.1007/s00122-021-03955-3

Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J. A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B. H., Ermolaeva, M., Ewald, C. Y., Ferrucci, L., Florian, M. C. ... Scheibye-Knudsen, M. (2022). Meeting Report: Aging Research and Drug Discovery. Aging, 14(2), 532-543. https://doi.org/10.18632/aging.203859

Privé, F., Aschard, H., Carmi, S., Folkersen, L., Hoggart, C., O'Reilly, P. F. & Vilhjálmsson, B. J. (2022). Portability of 245 polygenic scores when derived from the UK Biobank and applied to 9 ancestry groups from the same cohort. American Journal of Human Genetics, 109(1), 12-23. https://doi.org/10.1016/j.ajhg.2021.11.008

Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium & iPSYCH (2022). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry, 91(1), 102-117. https://doi.org/10.1016/j.biopsych.2021.02.972

Winkler, M. B. L., Nel, L., Frain, K. M., Dedic, E., Olesen, E. & Pedersen, B. P. (2022). Sterol uptake by the NPC system in eukaryotes: a Saccharomyces cerevisiae perspective. FEBS Letters, 596(2), 160-179. https://doi.org/10.1002/1873-3468.14253

Braunger, K., Ahn, J., Jore, M. M., Johnson, S., Tang, T. T. L., Pedersen, D. V., Andersen, G. R. & Lea, S. M. (2022). Structure and function of a family of tick-derived complement inhibitors targeting properdin. Nature Communications, 13, Artikel 317. https://doi.org/10.1038/s41467-021-27920-2

Thodberg, K., Foldager, L., Fogsgaard, K. K., Gaillard, C. & Herskin, M. S. (2022). Temperature conditions during commercial transportation of cull sows to slaughter. Computers and Electronics in Agriculture, 192, Artikel 106626. https://doi.org/10.1016/j.compag.2021.106626

Bergeron, L. A., Besenbacher, S., Turner, T. N., Versoza, C. J., Wang, R. J., Price, A. L., Armstrong, E., Riera, M., Carlson, J., Chen, H. Y., Hahn, M. W., Harris, K., Kleppe, A. S., López-Nandam, E. H., Moorjani, P., Pfeifer, S. P., Tiley, G. P., Yoder, A. D., Zhang, G. & Schierup, M. H. (2022). The mutationathon highlights the importance of reaching standardization in estimates of pedigree-based germline mutation rates. eLife, 11, Artikel e73577. https://doi.org/10.7554/eLife.73577

Hansen, E. K. B., Fredsøe, J. H., Okholm, T. L. H., Ulhøi, B. P., Klingenberg, S., Jensen, J. B., Kjems, J., Bouchelouche, K., Borre, M., Damgaard, C. K., Pedersen, J. S., Kristensen, L. S. & Sørensen, K. D. (2022). The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer. Genome Medicine, 14(1), Artikel 8. https://doi.org/10.1186/s13073-021-01009-3

Pierre-Ferre, S., Collins, B., Lukacsovich, D., Wen, SA., Chai, Y., Winterer, J., Auerbach, B., Li, M., Yan, J., Pedersen, L., Földy, C. & Brown, S. A. (2022). A single atypical phosphoswitch in specific SCN neurons gates winter seasonality in mice. Poster session præsenteret på Society for Research on Biological Rhythms Biennial Conference, Amelia Island, Florida, USA.

Rasmusson, A. G., Møller, I. M. & Widell, S. (2022). Assessment of Respiratory Enzymes in Intact Cells by Permeabilization with Alamethicin. I O. Van Aken & A. G. Rasmusson (red.), Plant Mitochondria (s. 77-84). Humana Press. https://doi.org/10.1007/978-1-0716-1653-6_7

Larsen, K. E. (2022). Balaena mysticetus Nei-like DNA glycosylase 3 (NEIL3) mRNA, partial cds. GenBank Access No. OL770101. Datasæt

Nayeri, Z., Aliakbari, F., Afzali, F., Parsafar, S., Gharib, E., Otzen, D. E. & Morshedi, D. (2022). Characterization of exogenous αSN response genes and their relation to Parkinson's disease using network analyses. Frontiers in Pharmacology, 13, Artikel 966760. https://doi.org/10.3389/fphar.2022.966760

Bofill-De Ros, X., Hong, Z., Birkenfeld, B., Alamo-Ortiz, S., Yang, A., Dai, L. & Gu, S. (2022). Flexible pri-miRNA structures enable tunable production of 5' isomiRs. RNA Biology, 19(1), 279-289. https://doi.org/10.1080/15476286.2022.2025680, https://doi.org/10.1080/15476286.2022.2025680

Bataillon, T., Gauthier, P., Villesen, P., Santoni, S., Thompson, J. D. & Ehlers, B. (2022). From genotype to phenotype: Genetic redundancy and the maintenance of an adaptive polymorphism in the context of high gene flow. Evolution Letters, 6(189-202). https://doi.org/10.1002/evl3.277

Rasmusson, A. G., Hao, M. & Møller, I. M. (2022). Integrity Assessment of Isolated Plant Mitochondria. I O. Van Aken & A. G. Rasmusson (red.), Plant Mitochondria (s. 51-62). Humana Press. https://doi.org/10.1007/978-1-0716-1653-6_5

Hansen, S. B. & Andersen, K. R. (2022). Introducing Cysteines into Nanobodies for Site-Specific Labeling. I G. Hussack & K. A. Henry (red.), Single-Domain Antibodies: Methods and Protocols (s. 327-343). Humana Press. https://doi.org/10.1007/978-1-0716-2075-5_16

Rasmusson, A. G., Møller, I. M. & Widell, S. (2022). Isolation of Highly Purified, Intact, and Functional Mitochondria from Potato Tubers Using a Two-in-One Percoll Density Gradient. I O. Van Aken & A. G. Rasmusson (red.), Plant Mitochondria (s. 39-50). Humana Press. https://doi.org/10.1007/978-1-0716-1653-6_4

Ferrando, B., Møller, I. M. & Stevnsner, T. (2022). Measuring the Activity of DNA Repair Enzymes in Isolated Mitochondria. I Plant Mitochondria (s. 321-334). Humana Press. https://doi.org/10.1007/978-1-0716-1653-6_21

Sanchez-Roman, I., Ferrando, B., Holst, C. M., Mengel-From, J., Rasmussen, S. H., Thinggaard, M., Bohr, V. A., Christensen, K. & Stevnsner, T. (2022). Molecular markers of DNA repair and brain metabolism correlate with cognition in centenarians. GeroScience, 44(1), 103-125. https://doi.org/10.1007/s11357-021-00502-2

Gobet, A., Jaxel, C., Magnard, S., Garrigos, M., Orlowski, S., Jamin, N., Falson, P. & Chaptal, V. (2022). Overexpression of the ABC Transporter BmrA Within Intracellular Caveolae in Escherichia coli. I Heterologous Expression of Membrane Proteins (Bind 2507, s. 79-89). Springer. https://doi.org/10.1007/978-1-0716-2368-8_5

Alam, P., Holst, M. R., Lauritsen, L., Nielsen, J., Nielsen, S. S. E., Jensen, P. H., Brewer, J. R., Otzen, D. E. & Nielsen, M. S. (2022). Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers. Fluids and Barriers of the CNS, 19(1), Artikel 37. https://doi.org/10.1186/s12987-022-00334-y

Keller-Socin, J. G., Petersen, K. V., Knudsen, B. R. & Tesauro, C. (2022). Simple and Fast DNA-Based Tool to Investigate Topoisomerase 1 Activity, a Biomarker for Drug Susceptibility in Colorectal Cancer. I Simple and Fast DNA-Based Tool to Investigate Topoisomerase 1 Activity, a Biomarker for Drug Susceptibility in Colorectal Cancer InTechOpen. https://doi.org/10.5772/intechopen.105758

Tesch-Römer, C., Wahl, H.-W., Rattan, S. & Ayalon, L. (2022). Successful Ageing: Ambition and Ambivalence. Oxford University Press. https://doi.org/10.1093/med/9780192897534.001.0001

Larsen, K. E. (2022). Sus scrofa domesticus cerebral dopamine neurotrophic factor (CDNF) mRNA, complete cds. GenBank Access No. OK268246. Datasæt

Larsen, K. E. (2022). Sus scrofa domesticus mesenecephalic astrocyte-derived neurotrophic factor (MANF) gene, promoter region and partial cds. GenBank Access No. OK337617. Datasæt

Fruergaard, M. U., Dach, I., Andersen, J. L., Ozol, M., Shasavar, A., Quistgaard, E. M. H., Poulsen, H., Fedosova, N. & Nissen, P. (2022). The Na,K-ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state. Journal of Biological Chemistry, 298(9), Artikel 102317. https://doi.org/10.1016/j.jbc.2022.102317

Tapia-Galisteo, A., Sánchez Rodríguez, Í., Aguilar-Sopeña, O., Harwood, S. L., Narbona, J., Ferreras Gutierrez, M., Navarro, R., Martín-García, L., Corbacho, C., Compte, M., Lacadena, J., Blanco, F. J., Chames, P., Roda-Navarro, P., Álvarez-Vallina, L. & Sanz, L. (2022). Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer. OncoImmunology, 11(1), Artikel 2034355. https://doi.org/10.1080/2162402X.2022.2034355

Eating Disorders Working Group of the Psychiatric Genomics Consortium (2021). Anorexia nervosa and inflammatory bowel diseases-Diagnostic and genetic associations. JCCP Advances, 1(4), e12036. Artikel e12036. https://doi.org/10.1002/jcv2.12036

Choong, F. X., Huzell, S., Rosenberg, M., Eckert, J. A., Nagaraj, M., Zhang, T., Melican, K., Otzen, D. E. & Richter-Dahlfors, A. (2021). A semi high-throughput method for real-time monitoring of curli producing Salmonella biofilms on air-solid interfaces. Biofilm, 3, Artikel 100060. https://doi.org/10.1016/j.bioflm.2021.100060

Valero, J., Civit, L., Dupont, D. M., Selnihhin, D., Reinert, L. S., Idorn, M., Israels, B. A., Bednarz, A. M., Bus, C., Asbach, B., Peterhoff, D., Pedersen, F. S., Birkedal, V., Wagner, R., Paludan, S. R. & Kjems, J. (2021). A serum-stable RNA aptamer specific for SARS-CoV-2 neutralizes viral entry. Proceedings of the National Academy of Sciences (PNAS), 118(50), Artikel e2112942118. https://doi.org/10.1073/pnas.2112942118

Green, K., Wittenborn, T. R., Fahlquist-Hagert, C., Terczynska-Dyla, E., van Campen, N., Jensen, L., Reinert, L., Hartmann, R., Paludan, S. R. & Degn, S. E. (2021). B Cell Intrinsic STING Signaling Is Not Required for Autoreactive Germinal Center Participation. Frontiers in Immunology, 12, Artikel 782558. https://doi.org/10.3389/fimmu.2021.782558

Brulefert, A., Kraemer, M., Cumin, M., Selle, A., Hoste, A., Gad, H.-H., Rühl, J., Madinier, J.-B., Chaloin, O., Münz, C., Desprès, P., Mueller, C. G. & Flacher, V. (2021). Chikungunya Virus Envelope Protein E2 Provides a Vector for Targeted Antigen Delivery to Human Dermal CD14⁺ Dendritic Cells. The Journal of Investigative Dermatology, 141(12), 2985-2989.e5. https://doi.org/10.1016/j.jid.2021.04.027

Buggiotti, L., Cheng, Z., Salavati, M., Wathes, D. C. & GplusE Consortium (2021). Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes. BMC Genomics, 22(1), 1-17. Artikel 693. https://doi.org/10.1186/s12864-021-07977-5

Larsen, K. & Heide-Jørgensen, M. P. (2021). Conservation of A-to-I RNA editing in bowhead whale and pig. PLOS ONE, 16(12 ), Artikel e0260081. https://doi.org/10.1371/journal.pone.0260081

Fujito, S., Akyol, T. Y., Mukae, T., Wako, T., Yamashita, K. I., Tsukazaki, H., Hirakawa, H., Tanaka, K., Mine, Y., Sato, S. & Shigyo, M. (2021). Construction of a high-density linkage map and graphical representation of the arrangement of transcriptome-based unigene markers on the chromosomes of onion, Allium cepa L. BMC Genomics, 22(1), Artikel 481. https://doi.org/10.1186/s12864-021-07803-y

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Lisbeth Heilesen